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Applied Mathematics(A Journal of Chinese Universities) 2024年第1期39卷 181-190页

作者： REN guang-zhen SHI Yun KANG qian-qian Department of Mathematics Zhejiang International Studies UniversityHangzhou 310023China Department of Mathematics Zhejiang University of Science and TechnologyHangzhou 310023China

The tangential k-Cauchy-Fueter operator and k-CF functions are counterparts of the tangential Cauchy–Riemann operator and CR functions on the Heisenberg group in the theory of several complex variables,*** this paper,we introduce a Lie group that the Heisenberg group can be imbedded into and call it generalized complex *** investigate quaternionic analysis on the generalized complex *** also give the Penrose integral formula for k-CF functions and construct the tangential k-Cauchy-Fueter complex.

关键词： the generalized complex Heisenberg group the tangential k-Cauchy-Fueter type operator Penrose-type integral formula

A Novel Method for Forecasting Freak Wave Occurrence in A Short Crested Coastal Sea

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China Ocean Engineering 2024年第1期38卷 104-116页

作者： wang Ying-guang State Key Laboratory of Ocean Engineering Shanghai Jiao Tong UniversityShanghai 200240China School of Ocean and Civil Engineering Shanghai Jiao Tong UniversityShanghai 200240China

In order to forecast the distribution of crest amplitudes and the occurrence of freak waves in a short crested coastal sea,a novel transformed linear simulation method is initially proposed in this paper.A Hermite transformation model expressed as a monotonic cubic polynomial serves as the foundation for the novel simulation *** wave crest amplitude exceedance probabilities of two sea states-one with a directional wave spectrum based on the measured wave elevation data at the Yura coast and the other with a typical directional JONSWAP wave spectrum-have been predicted using the novel simulation method that has been *** likelihood that a particular critical wave crest amplitude will be exceeded is directly correlated with the probability that freak waves will *** is shown that the novel simulation approach suggested can provide predictions that are more precise than those obtained from the Rayleigh crest amplitude distribution model,the Jahns and Wheeler crest amplitude distribution model,or the conventional linear simulation *** study also demonstrated that the nonlinear simulation method is less effective than the novel simulation method in terms of efficiency.

关键词： wave crest amplitude freak waves short crested sea transformed linear simulation

Derivatives of Intersection Local Time for Two Independent Symmetricα-stable Processes

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Acta Mathematica Sinica,English Series 2024年第5期40卷 1273-1292页

作者： Huan ZHOU guang Jun SHEN qian YU Department of Mathematics Anhui Normal UniversityWuhu 241002P.R.China Department of Mathematics Nanjing University of Aeronautics and AstronauticsNanjing 211106P.R.China Key Laboratory of Mathematical Modelling and High Performance Computing of Air Vehicles(NUAA) MIITNanjing 211106P.R.China

In this paper,we consider the derivatives of intersection local time for two independent d-dimensional symmetricα-stable processes X^(α) and X^(α)with respective indices α and α.We first study the sufficient condition for the existence of the derivatives,which makes us obtain the exponential integrability and H?lder *** we show that this condition is also necessary for the existence of derivatives of intersection local time at the ***,we also study the power variation of the derivatives.

关键词： Symmetric stable processes intersection local time exponential integrability power variation

The study of intelligent algorithm in particle identification of heavy-ion collisions at low and intermediate energies

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Nuclear Science and Techniques 2024年第2期35卷 170-182页

作者： Gao-Yi Cheng qian-Min Su Xi-guang Cao Guo-qiang Zhang School of Electronic and Electrical Engineering Shanghai University of Engineering ScienceShanghai 201620China Shanghai Advanced Research Institute Chinese Academy of SciencesShanghai 201210China Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China

Traditional particle identification methods face timeconsuming,experience-dependent,and poor repeatability challenges in heavy-ion collisions at low and intermediate *** urgently need solutions to the dilemma of traditional particle identification *** study explores the possibility of applying intelligent learning algorithms to the particle identification of heavy-ion collisions at low and intermediate *** intelligent algorithms,including XgBoost and TabNet,were selected to test datasets from the neutron ion multi-detector for reaction-oriented dynamics(NIMROD-ISiS)and Geant4 ***-based machine learning algorithms and deep learning algorithms *** show excellent performance and generalization *** additional data features besides energy deposition can improve the algorithm’s performance when the data distribution is *** learning algorithms can be applied to solve the particle identification problem in heavy-ion collisions at low and intermediate energies.

关键词： Heavy-ion collisions at low and intermediate energies Machine learning Ensemble learning algorithm Particle identification Data imbalance

Two missense STK11 gene variations impaired LKB1/adenosine monophosphate-activated protein kinase signaling in Peutz-Jeghers syndrome

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1532-1546页

作者： Jin Liu Si-Cong Zeng An wang Hai-Ying Cheng qian-Jun Zhang guang-Xiu Lu Hunan guangxiu Hospital Hunan Normal UniversityChangsha 410000Hunan ProvinceChina Scientific Research Department Reproductive and Genetic Hospital of Citic-XiangyaChangsha 410000Hunan ProvinceChina

BACKGROUND Peutz-Jeghers syndrome(PJS)is a rare hereditary neoplastic disorder mainly associated with serine/threonine kinase 11(STK11/LKB1)gene *** genetic testing can protect a patient’s offspring from mutated genes;however,some variations in this gene have been interpreted as variants of uncertain significance(VUS),which complicate reproductive decision-making in genetic *** To identify the pathogenicity of two missense variants and provide clinical *** Whole exome gene sequencing and Sanger sequencing were performed on the peripheral blood of patients with PJS treated at the Reproductive and Genetic Hospital of *** was employed to predict the protein structure,conservation,and pathogenicity of the two missense variation sites in patients with ***,plasmids were constructed and transfected into HeLa cells to observe cell *** differences in signal pathway expression between the variant group and the wild-type group were compared using western blot and *** analysis was performed using one-way analysis of variance.PG(***297Gly)and c.733C>T(***245Phe)]in 9 unrelated PJS families who were seeking reproductive *** two missense VUS were located in the catalytic domain of serine/threonine kinase,which is a key structure of the liver kinase B1(LKB1)*** vitro experiments showed that the phosphorylation levels of adenosine monophosphate-activated protein kinase(AMPK)at Thr172 and LKB1 at Ser428 were significantly higher in transfected variation-type cells than in wild-type *** addition,the two missense STK11 variants promoted the proliferation of HeLa *** immunohistochemical analysis showed that phosphorylated-AMPK(Thr172)expression was significantly lower in gastric,colonic,and uterine polyps from PJS patients with misse

关键词： Missense STK11 Peutz-Jeghers syndrome Rare disease Genetic counseling Assisted reproductive technique

Spatial Distribution Pattern and Influencing Factors of Bed-and-breakfasts(B&Bs)from the Perspective of Urban-rural Differences:A Case Study of Jiaodong Peninsula,China

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Chinese Geographical Science 2024年第4期34卷 752-763页

作者： wang Xinyue MA qian Management College Ocean University of ChinaQingdao 266100China

There are significant differences between urban and rural bed-and-breakfasts(B&Bs)in terms of customer positioning,economic strength and spatial *** identifying the differences in spatial characteristics and influencing factors of each type,is essential for creating urban and rural B&B agglomeration *** study used density-based spatial clustering of applications with noise(DBSCAN)and the multi-scale geographically weighted regression(MGWR)model to explore similarities and differences in the spatial distribution patterns and influencing factors for urban and rural B&Bs on the Jiaodong Peninsula of China from 2010 to *** results showed that:1)both urban and rural B&Bs in Jiaodong Peninsula went through three stages:a slow start from 2010 to 2015,rapid development from 2015 to 2019,and hindered development from 2019 to ***,urban B&Bs demonstrated a higher development speed and agglomeration intensity,leading to an increasingly evident trend of uneven development between the two sectors.2)The clustering scale of both urban and rural B&Bs continued to expand in terms of quantity and *** B&B clusters characterized by a limited number,but a higher likelihood of transitioning from low-level to high-level *** the number of rural B&B clusters steadily increased over time,their clustering scale was comparatively lower than that of urban B&Bs,and they lacked the presence of high-level clustering.3)In terms of development direction,urban B&B clusters exhibited a relatively stable pattern and evolved into high-level clustering centers within the main urban ***,rural B&Bs exhibited a more pronounced spatial diffusion effect,with clusters showing a trend of multi-center development along the coastline.4)Transport emerged as a common influencing factor for both urban and rural B&Bs,with the density of road network having the strongest explanatory power for their spatial *** terms of differences,populati

关键词： urban-rural bed-and-breakfasts(B&Bs) spatiotemporal evolution density-based spatial clustering of applications with noise(DBSCAN)model multi-scale geographically weighted regression(MGWR) Jiaodong Peninsula China

A Bed-load function based on kinetic theory

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International Journal of Sediment Research 2012年第4期27卷 460-472页

作者： De-yu ZHONG guang-qian wang Lei ZHANG State key laboratory of Hydroscience and Engineering Tsinghua Univ.

Bed-load transport plays a fundamental role in morphological processes of natural rivers and human-made *** paper presents bed-load function derived on the basis of kinetic theory. The bed-load function is obtained by integrating the pick-up rate of bed sediment with respect to its longitudinal travel distance,following the basic concept on bed-load put forward by *** pick-up rate is expressed as an upwards flux of bed sediment and determined by invoking the particle velocity distribution function derived by solving the Boltzmann equation of kinetic theory. Comparisons of the present formula with six other bed-load formulas and the experimental data are also made in this *** results show that the present bed-load formula agrees well with the experimental *** addition,the influences due to collision between particles on bed-load is discussed which shows that an appreciable damping of the intensities of bed-load is observed only when the shear acting on particles is large enough to increase the concentration and intensity of random motion of bed load particles so that the collisions between sediment particles can occur.

关键词： Bed load Sediment transport Open channel flow Turbulence Two phase flow

Differentially private SGD with random features

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Applied Mathematics(A Journal of Chinese Universities) 2024年第1期39卷 1-23页

作者： wang Yi-guang GUO Zheng-chu Polytechnic Institute of Zhejiang University Zhejiang UniversityHangzhou 310015China School of Mathematical Sciences Zhejiang UniversityHangzhou 310058China

In the realm of large-scale machine learning,it is crucial to explore methods for reducing computational complexity and memory demands while maintaining generalization ***,since the collected data may contain some sensitive information,it is also of great significance to study privacy-preserving machine learning *** paper focuses on the performance of the differentially private stochastic gradient descent(SGD)algorithm based on random *** begin,the algorithm maps the original data into a lowdimensional space,thereby avoiding the traditional kernel method for large-scale data storage ***,the algorithm iteratively optimizes parameters using the stochastic gradient descent ***,the output perturbation mechanism is employed to introduce random noise,ensuring algorithmic *** prove that the proposed algorithm satisfies the differential privacy while achieving fast convergence rates under some mild conditions.

关键词： learning theory differential privacy stochastic gradient descent random features reproducing kernel Hilbert spaces

Molecular Mechanism of Rice Necrotic Lesion for Optimized Yield and Disease Resistance

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Rice science 2024年第3期31卷 285-299页

作者： HOU Xinyue wang Yuping qian qian REN Deyong State Key Laboratory of Rice Biology and Breeding China National Rice Research InstituteHangzhou 310006China State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China Rice Research InstituteSichuan Agricultural UniversityChengdu 611130China

How to balance rice resistance and yield is an important issue in rice *** with mutated necrotic lesion genes often have persistent broad-spectrum resistance,but this broad-spectrum resistance usually comes at the expense of ***,many necrotic lesion mutants in rice have been identified,and these genes are involved in disease resistance *** review provides a detailed introduction to the characteristics,classification,and molecular mechanisms of necrotic lesion ***,we review the molecular regulatory pathways of genes involved in rice disease ***,we summarize the relationship between resistance and yield in rice using newly developed gene editing *** discuss a rational and precise breeding strategy to better utilize molecular design technology for breeding disease-resistant and high-yield rice varieties.

关键词： rice necrotic lesion regulation mechanism high yield high resistance

Sodium Sulfite as a Novel Hypoxia Revulsant Involved in Hypoxic Regulation in Escherichia coli

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Biomedical and Environmental Sciences 2024年第2期37卷 228-232页

作者： YE Qiao HUO Jia Nan LUO Yuan MEI Zhu Song FANG Long Mei GUO Bing qian wang guang Yun Laboratory of clinical medicine Air Force Medical CenterAir Force Medical UniversityBeijing 100142China

As a reducing salt,sodium sulfite could deprive oxygen in solution,which could mimic hypoxic stress in Caenorhabditis *** this study,the wildtype Escherichia coli strain MG1655 was used to examine the inhibition of so... 详细信息

关键词： hypoxic Sodium observing