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Simulation study of BESⅢwith stitched CMOS pixel detector using AcTs

Nuclear Science and Techniques 2023年第12期34卷 264-270页

作者： Yi Liu xiao‑Cong Ai guang‑yan xiao Ya‑Xuan Li Ling‑Hui Wu Liang‑Liang Wang Jia‑Ning Dong Ming‑Yi Dong Qing‑Lin Geng Min Luo yan Niu An‑Qing Wang Chen‑Xu Wang Meng Wang Lei Zhang Liang Zhang Rui‑Kai Zhang Yao Zhang Ming‑Gang Zhao yang Zhou School of Physics and Microelectronics Zhengzhou UniversityZhengzhou 450001China School of Physics Nanjing UniversityNanjing 210093China School of Physics Nankai UniversityTianjin 300071China Institute of High Energy Physics Chinese Academy of Sciences19B Yuquan RoadShijingshan DistrictBeijing 100049China Research Center for Particle Science and Technology Institute of Frontier and Interdisciplinary ScienceShandong UniversityQingdao 266237China University of Chinese Academy of Sciences 19A Yuquan RoadShijingshan DistrictBeijing 100049China School of Information Science and Engineering Harbin Institute of TechnologyWeihai 264209China

The reconstruction of the tracks of charged particles with high precision is crucial for HEP experiments to achieve their physics *** BESⅢdrift chamber,which is used as the tracking detector of the BESⅢexperiment,has suffered from aging effects resulting in degraded tracking performance after operation for approximately 15 *** preserve and enhance the tracking performance of BESⅢ,one of the proposals is to add one layer of a thin cylindrical CMOS pixel sensor based on state-of-the-art stitching technology between the beam pipe and the drift *** improvement in the tracking performance of BESⅢwith such an additional pixel detector compared to that with only the existing drift chamber was studied using the modern common tracking software Acts,which provides a set of detector-agnostic and highly performant tracking algorithms that have demonstrated promising performance for a few high-energy physics and nuclear physics experiments.

关键词： BESⅢtracking detector CMOS pixel sensor Track reconstruction Common tracking software

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Infrared and MAS NMR Spectroscopic Studies of Al_(18)B_4O_(33)

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Chemical Research in Chinese Universities 2000年第4期16卷 301-305页

作者： YOU Hong-peng, HONG guang-yan and ZENG xiao-qing (Laboratory of Rare Earth Chemistry and Physics, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China) DENG Feeng and YE Zhao-hui (Laboratory of Magnetic Reso Chinese Acad of Sciences Changchun China

The IR spectrum and 11B and 27Al MAS NMR spectra of Al18B4O33 are presented and discussed in relation to the possible existence of boron atoms substituting for aluminum atoms. The IR spectrum shows that the strong vibrations of the BO3 groups are present in the 1 500-1 200 cm-1 region, and very weak bands of BO4 units are present in the region from 1 000 to 1 100 cm-1. 11B MAS NMR spectrum indicates that the strong signal for BO3 units appears in the region from δ+5 to δ+20, and the very weak signal for BO4 units is at about δ- 1, while 27Al MAS NMR spectrum shows five peaks at about δ+62, +42. 1, +14, -4. 7 and -6. 4, originating from AlO4, AlO4, AlO5, AlO6 and AlO6, respectively. These results reveal that there are minor BO4 units in Al18B4O33, indicating that a small amount of B atoms substitute for Al atoms in the 4-fold coordination.

关键词： Al-18B_4O_33 IR spectrum,^(11)B,^(27)Al MAS NMR spectrum

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In vitro spermatogenesis from embryonic stem cells in a chemical defined serum-free and feeder-free culture system

In vitro spermatogenesis from embryonic stem cells in a chem...

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2012全国发育生物学大会

作者： Hua-Lin Yi,guang-yan Kan,Sa xiao,Jun-Jiu Huang,yan Zhang School of Life Sciences,Sun Yat-sen University,guangzhou 510006

Embryonic stem cells(ESCs),which derived from the inner cell mass in the blastocyst,show the totipotent characteristics to differentiate into all three germ layers,containing the gametes as sperms and *** of functional sperms from ESCs in vitro could offer an important technical platform for the research on fertilization and individual *** researches focused on generating sperms from ESC clones,embryonic bodies(EBs) or primordial germ cells(PGCs) by endogenous control of gene expression or exogenous control of defined ***, low efficiency of the introduction process from ESCs or EBs and unrepeatable performance have hampered progress with this *** the present study,we modified the culture system for the induced differentiation from ESCs or EBs to PGCs,then the haploid gametes via *** to conventional maintenance and differentiation conditions basically using serum and feeder cells,we devoted to introduce a thoroughly serum-free and feeder-free system as monolayer and 3-D culture *** two different systems,we prepared ESC clones adhered to the dishes and suspended EB spheres at modest size ***-defined medium containing definite cytokines were used for *** on this serum-free and feeder-free culture system,we paid close attention to the spermatogenesis procedure at pivotal points, such as PGC initiation,transformation across meiosis,even the maturation of elongated sperm cells responding to each chemical-defined *** addition,we tracked out the expression profile and communication networks of hallmark genes and proteins represented typical features of different developmental stages of *** results provide an important cue for understanding the contributing molecular networks in the progress of spermatogenesis,and stimulate further research in this area as well. Conclusions:Our data showed that ESCs or EBs could be maintained and induced to form

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过冷水滴凝固特性的计算与实验研究

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工程热物理学报 2017年第10期38卷 2196-2201页

作者：肖光明杜雁霞李伟斌王桥易贤桂业伟中国空气动力研究与发展中心空气动力学国家重点实验室绵阳621000

针对飞机结冰的特殊凝固过程,基于Enthalpy-porosity模型,发展了改进的结冰特性预测模型及数值计算方法,并基于凝固实验开展了所建模型及预测方法的验证。研究表明,相对于传统Enthalpy-porosity方法,所发展的方法可有效表征非平衡凝固过... 详细信息

针对飞机结冰的特殊凝固过程,基于Enthalpy-porosity模型,发展了改进的结冰特性预测模型及数值计算方法,并基于凝固实验开展了所建模型及预测方法的验证。研究表明,相对于传统Enthalpy-porosity方法,所发展的方法可有效表征非平衡凝固过程,因而对冷水滴凝固特性的表征具有较好的改进。基于所建方法,开展了水滴凝固特性的影响因素分析,获得了不同过冷条件下水滴凝固过程的温度分布及相界面变化特征。相关研究可为结冰热力学模型的改进,以及结冰特性的精细化预测提供重要参考。

关键词：过冷水滴飞机结冰凝固相变

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飞秒激光刻写FBG在电极放电下的光谱特性

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激光与红外 2017年第1期47卷 103-107页

作者：辛璟焘庄炜闫光娄小平祝连庆北京信息科技大学光电信息与仪器北京市工程研究中心光电测试技术北京市重点实验室北京100016 北京信息科技大学生物医学检测技术及仪器北京实验室北京100192

采用电极脉冲电弧放电对紫外激光和飞秒激光刻写的光纤布拉格光栅(FBG)进行高温激励的研究,实验发现,紫外激光刻写的FBG,光栅透射谱大幅下降,光谱蓝移0.38 nm,飞秒激光刻写的FBG透射谱基本保持不变,光谱红移0.022 nm。特别是当电极在栅... 详细信息

采用电极脉冲电弧放电对紫外激光和飞秒激光刻写的光纤布拉格光栅(FBG)进行高温激励的研究,实验发现,紫外激光刻写的FBG,光栅透射谱大幅下降,光谱蓝移0.38 nm,飞秒激光刻写的FBG透射谱基本保持不变,光谱红移0.022 nm。特别是当电极在栅区中心位置放电时,光栅透射率上升达到最大,比无电极放电时大8 d B,表现出开关量特性。该特性在光纤开关量器件、光纤调Q激光器、新型光纤光栅解调与局部放电检测等领域具有潜在的应用前景。

关键词：光纤布拉格光栅飞秒激光电极放电开关量传感器

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miRNA-21-5p is an important contributor to the promotion of injured peripheral nerve regeneration using hypoxia-pretreated bone marrow-derived neural crest cells

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Neural Regeneration Research 2025年第1期20卷 277-290页

作者： Meng Cong Jing-Jing Hu yan Yu xiao-Li Li xiao-Ting Sun Li-Ting Wang Xia Wu Ling-Jie Zhu xiao-Jia yang Qian-Ru He Fei Ding Hai-yan Shi School of Medicine Nantong UniversityNantongJiangsu ProvinceChina Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education and Coinnovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Physiology Jiangsu Health Vocational CollegeNanjingJiangsu ProvinceChina Department of Pathology Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina Jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury Repair Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina

Our previous study found that rat bone marrow–derived neural crest cells(acting as Schwann cell progenitors)have the potential to promote long-distance nerve ***-based therapy can enhance peripheral nerve repair and regeneration through paracrine bioactive factors and intercellular ***,the complex contributions of various types of soluble cytokines and extracellular vesicle cargos to the secretome remain *** investigate the role of the secretome and extracellular vesicles in repairing damaged peripheral nerves,we collected conditioned culture medium from hypoxia-pretreated neural crest cells,and found that it significantly promoted the repair of sensory neurons damaged by oxygen-glucose *** mRNA expression of trophic factors was highly expressed in hypoxia-pretreated neural crest *** performed RNA sequencing and bioinformatics analysis and found that miR-21-5p was enriched in hypoxia-pretreated extracellular vesicles of neural crest ***,to further clarify the role of hypoxia-pretreated neural crest cell extracellular vesicles rich in miR-21-5p in axonal growth and regeneration of sensory neurons,we used a microfluidic axonal dissociation model of sensory neurons in vitro,and found that hypoxia-pretreated neural crest cell extracellular vesicles promoted axonal growth and regeneration of sensory neurons,which was greatly dependent on loaded ***,we constructed a miR-21-5p-loaded neural conduit to repair the sciatic nerve defect in rats and found that the motor and sensory functions of injured rat hind limb,as well as muscle tissue morphology of the hind limbs,were obviously *** findings suggest that hypoxia-pretreated neural crest extracellular vesicles are natural nanoparticles rich in ***-21-5p is one of the main contributors to promoting nerve regeneration by the neural crest cell *** helps to explain the mechanism of action of the secretome and e

关键词： axotomy cell-free therapy conditioned medium extracellular vesicles hypoxic preconditioning microRNA oxygen-glucose deprivation peripheral nerve injury Schwann cell precursors

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Metal nanoparticles decorated CoFe-(oxy)hydroxysulfides nanosheets fabricated by a general strategy for electrocatalytic water splitting

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Journal of Energy Chemistry 2025年第1期100卷 26-38页

作者： xiaodong yang Haochen Shen xiaoming xiao Zhichao Li Qi Zhou Wei yang Bin Jiang Yongli Sun Luhong Zhang Zhenhua yan School of Chemical Engineering and Technology Tianjin University Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education) Nankai University

This study presents a novel method to fabricate metal-decorated,sulfur-doped layered double hydroxides （M/SLDH） through spontaneous redox and sulfurization *** developed Ag/SLDH and Pt/SLDH catalysts with abundant heterogeneous interfaces and hierarchical nanostructures demonstrated outstanding oxygen evolution reaction （OER） and hydrogen evolution reaction （HER） performance,achieving low overpotentials of 212 and 35 mV at 10 mA cm-2in 1 M KOH,*** both anode and cathode in water splitting,they required only 1.47 V to reach 10 mA cm-2and exhibited high structural robustness,maintaining stability at 1000 mA cm-2for 300 ***-situ Raman analysis revealed that the synergistic effects of metal nanoparticles and S doping significantly promote the transformation into the S-Co1-xFexOOH layer,which serves as the active phase for water ***,ultraviolet photoelectron spectroscopy （UPS） and density functional theory （DFT） analyses indicated that incorporating metal nanoparticles and S doping increase electron density near the Fermi level and reduce reaction energy barriers,thus enhancing intrinsic OER and HER *** study provides a scalable strategy for synthesizing high-performance electrocatalysts for water splitting,with promising potential for broader applications.

关键词： LDH Spontaneous reaction Metal nanoparticles Water splitting

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Endoplasmic reticulum stress and autophagy in cerebral ischemia/reperfusion injury:PERK as a potential target for intervention

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Neural Regeneration Research 2025年第5期20卷 1455-1466页

作者： Ju Zheng Yixin Li Ting Zhang yanlin Fu Peiyan Long xiao Gao Zhengwei Wang Zhizhong Guan xiaolan Qi Wei Hong yan xiao Key Laboratory of Endemic and Ethnic Diseases Ministry of Education&Key Laboratory of Medical Molecular Biology of Guizhou ProvinceGuizhou Medical UniversityGuiyangGuizhou ProvinceChina Guizhou Center for Disease Control and Prevention GuiyangGuizhou ProvinceChina Department of Histology and Embryology Guizhou Medical UniversityGuiyangGuizhou ProvinceChina Collaborative Innovation Center for Prevention and Control of Endemic and Ethnic Regional Diseases Co-constructed by the Province and Ministry GuiyangGuizhou ProvinceChina

Several studies have shown that activation of unfolded protein response and endoplasmic reticulum(ER)stress plays a crucial role in severe cerebral ischemia/reperfusion *** occurs within hours after cerebral ischemia,but the relationship between ER stress and autophagy remains *** this study,we established experimental models using oxygen-glucose deprivation/reoxygenation in PC12 cells and primary neurons to simulate cerebral ischemia/reperfusion *** found that prolongation of oxygen-glucose deprivation activated the ER stress pathway protein kinase-like endoplasmic reticulum kinase(PERK)/eukaryotic translation initiation factor 2 subunit alpha(e IF2α)-activating transcription factor 4(ATF4)-C/EBP homologous protein(CHOP),increased neuronal apoptosis,and induced ***,inhibition of ER stress using inhibitors or by si RNA knockdown of the PERK gene significantly attenuated excessive autophagy and neuronal apoptosis,indicating an interaction between autophagy and ER stress and suggesting PERK as an essential target for regulating *** autophagy with chloroquine exacerbated ER stress-induced apoptosis,indicating that normal levels of autophagy play a protective role in neuronal injury following cerebral ischemia/reperfusion *** from this study indicate that cerebral ischemia/reperfusion injury can trigger neuronal ER stress and promote autophagy,and suggest that PERK is a possible target for inhibiting excessive autophagy in cerebral ischemia/reperfusion injury.

关键词： apoptosis ATF4 autophagy C/EBP homologous protein cerebral ischemia/reperfusion injury eIF2α endoplasmic reticulum stress PERK

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宫颈妊娠保守治疗12例临床分析

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河北医学 2007年第12期13卷 1273-1274页

作者：梁轶珩光晓燕北京大学深圳医院妇产科广东深圳518000

目的:分析宫颈妊娠的临床特征及探讨保守治疗疗效。方法:回顾性分析我院2002年至2006年12例宫颈妊娠的临床特征及采取保守治疗的效果。结果:12例宫颈妊娠皆采用保守治疗,其中7例行子宫动脉栓塞治疗,其余予米非司酮及MTX、中药保守治疗,... 详细信息

目的:分析宫颈妊娠的临床特征及探讨保守治疗疗效。方法:回顾性分析我院2002年至2006年12例宫颈妊娠的临床特征及采取保守治疗的效果。结果:12例宫颈妊娠皆采用保守治疗,其中7例行子宫动脉栓塞治疗,其余予米非司酮及MTX、中药保守治疗,治疗后定期随访,β-HCG下降满意。结论:宫颈妊娠可采取子宫动脉栓塞、药物等保守治疗。

关键词：宫颈妊娠保守治疗 11名床分析

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卵巢过度刺激综合征并发深静脉血栓临床研究并文献复习

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医学综述 2013年第10期19卷 1910-1912页

作者：光晓燕于琳李璟北京大学深圳医院妇产科深圳518036

目的分析卵巢过度刺激综合征(OHSS)并发深静脉血栓(DVT)的临床特征、诊疗方法及预防措施,以提高临床医师对该疾病的认识。方法回顾性分析北京大学深圳医院收治的2例OHSS并发DVT的临床资料,并检索相关文献,总结诊治经验。结果国内外文献... 详细信息

目的分析卵巢过度刺激综合征(OHSS)并发深静脉血栓(DVT)的临床特征、诊疗方法及预防措施,以提高临床医师对该疾病的认识。方法回顾性分析北京大学深圳医院收治的2例OHSS并发DVT的临床资料,并检索相关文献,总结诊治经验。结果国内外文献报道OHSS并发DVT 31例,27例报道其发病与辅助生殖技术(ART)有关,所有患者均使用低分子肝素治疗,效果良好,合并妊娠者可获得良好的妊娠结局。栓塞部位多发于上肢头颈部位。结论 OHSS并发DVT是ART相关的致命性并发症,虽然低分子肝素治疗有效,但积极预防OHSS发生是减少血栓发病的关键,对于高危人群尤其要提高警惕,必要时可进行易栓症筛查。

关键词：卵巢过度刺激综合征深静脉血栓辅助生殖技术低分子肝素

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