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The relationship between dNA fragmentation and the intensity of morphologically abnormal human spermatozoa

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Asian pacific Journal of Reproduction 2024年第1期13卷 22-27页

作者： Merced.s.González-Martínez Pascual sánchez-Martín Carmen López-Fernández stephen d.Johnston Jaime Gosálvez Clínica Ginemed Unidad de ReproducciónSevillaSpain department of Biology Universidad Autónoma de MadridCantoblancoMadridSpain school of Environment The University of QueenslandGattonAustralia school of Veterinary science The University of QueenslandGattonAustralia

Objective:To determine the relationship between teratozoospermia and.s.erm dNA fragmentation(sdF)in the human ***:This retrospective study included 100 normozoospermic men as a control cohort(abnormal forms>14%),210 patients with a high level of abnormal forms(≤4%)and 65 patients presenting with a moderate level of abnormal forms(>4%to≤14%)based on the World Health Organization *** morphology was assessed using bright field *** dNA fragmentation was assessed using the sperm chromatin d.s.ersion ***-parametric analyses were conducted to examine the relationship between abnormal sperm morphology and.s.erm dNA fragmentation;receiver operating characteristic(ROC)analyses were conducted to assess sensitivity and.s.ecificity of this ***:A correlation analysis revealed that the higher the proportion of abnormal spermatozoa in the ejaculate,the higher the level of sdF(spearman's Rho=-0.230;Psignificant differences in the proportion of sdF were found when all cohorts were compared(Pse significant differences were also retained when the different cohorts were compared *** analysis showed a moderate but significant predictive value for sdF to differentiate patients with different levels of ***:Although analysis of a more continuous range of values for teratozoospermia would help further clarify any causal relationship with sdF,there is clearly a synergistic or coincident affiliation between these variables that needs to be acknowledged by the clinician when interpreting the spermiogram.

关键词： Teratozoospermia sperm morphology sperm dNA fragmentation Male factor Human reproduction Human fertility

On the calibration of a shear stress criterion for rock joints to represent the full stress-strain profile

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第2期16卷 379-392页

作者： Akram deiminiat Jonathan d.Aubertin Yannic Ethier department of Construction Engineering École de Technologie Supérieure(ÉTS)MontréalCanada

Conventional numerical solutions developed to d.s.ribe the geomechanical behavior of rock interfaces subjected to differential load emphasize peak and residual shear *** detailed analysis of preand post-peak shear stress-d.s.lacement behavior is central to various time-dependent and dynamic rock mechanic problems such as rockbursts and.s.ructural instabilities in highly stressed *** complete stress-d.s.lacement surface(Csds)model was developed to d.s.ribe analytically the pre-and post-peak behavior of rock interfaces under differential *** formulations of the Csds model required extensive curve-fitting iterations which limited its practical applicability and transparent integration into engineering *** present work proposes modifications to the Csds model aimed at developing a comprehensive and modern calibration protocol to d.s.ribe the complete shear stressd.s.lacement behavior of rock interfaces under differential *** proposed update to the Csds model incorporates the concept of mobilized.s.ear strength to enhance the post-peak ***’s concepts of joint roughness coefficient(JRC)and joint compressive strength(JCs)are incorporated to facilitate empirical estimations for peak shear stress and normal closure ***/uniaxial compression test and direct shear test results are used to validate the updated model and exemplify the proposed calibration *** results illustrate that the revised model successfully predicts the post-peak and complete axial stressestrain and.s.ear stressed.s.lacement curves for rock joints.

关键词： Full shear profile Post-peak shear behavior Rock joint Joint roughness coefficient(JRC) Axial stress-strain curve

Impact of Paenibacillus elgii supernatant on screening bacterial strains with potential for biotechnological applications

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Engineering Microbiology 2024年第3期4卷 1-15页

作者： I.C.Cunha-Ferreira C.s.Vizzotto T.d.Frederico J.Peixoto L.s Carvalho M.R.Tótola R.H.Krüger Laboratory of Enzymology Department of Cellular BiologyUniversity of Brasília(UNB)Brasília70910-900Brazil Laboratory of Environmental sanitation Department of Civil and Environmental EngineeringUniversity of Brasília(UNB)Brasília70910-900Brazil Laboratório de Biotecnologia e Biodiversidade para o Meio Ambiente Universidade Federal de Viçosa(UFV)Viçosa36570-900Brazil

The biotechnological ind.s.ry faces a crucial demand for novel bioactive compounds,particularly antimicrobial agents,to address the rising challenge of bacterial resistance to current available *** strate-gies for cultivating naturally occurring microorganisms often limit the d.s.overy of novel antimicrobial *** study presents a protocol for targeted.s.lection of bacterial strains using the supernatant of Paenibacillus el-gii,which produces abundant signal molecules and antimicrobial *** samples were inoculated in these enriched culture media to selectively cultivate bacteria resistant to the supernatant,indicating their potential to produce similar *** bacterial strains isolated through this method were assessed for their antibac-terial *** addition,the functional annotation of the genome of one of these strains revealed.s.veral gene clusters of biotechnological *** study highlights the effectiveness of using this approach for selective cultivation of microorganisms with potential for biotechnological applications.

关键词： Prospecting supernatant Antibacterial activity

Prevalence of Gender-Based Violence among sex Workers in Bangui, Central African Republic (CAR)

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Advances in sexual Medicine 2024年第2期14卷 13-20页

作者： d. Mossoro-Kpinde Hermione s. C. diemer Henri R. Tende Nzengou Richard.s. siki Francis J. d. d. Tekpa Bertrand Ministry of Labor Employment Social Protection and Vocational Training Bangui Central African Republic department of Public Health Faculty of Health Sciences University of Bangui Bangui Central African Republic Community of the Tree of Life Bangui Central African Republic Traumatology department The Central African Republic RCA Community Hospital Bangui Central African Republic

Background: Violence against women has become an international public health and human rights issue in recent decad.s. The violence suffered by sex workers is of little interest for research, yet it constitutes a major health and.s.fety problem. We propose to assess the extent of the phenomenon of gender-based violence (GBV) among sex workers (sWs) in the city of Bangui in the CAR. Methodology: This is a d.s.riptive cross-sectional epidemiological study covering the period from July to October 2021 carried out among sWs in Bangui, the capital of the CAR. Given that the sWs association had only 159 members in Bangui, an exhaustive sampling was retained. Were included in the study, any sW present during the data collection period and having given their written consent. The parameters studied were socio-demographic characteristics: age, sex, residence, level of education, marital status, and characteristics linked to violence: the notion of violence during their professional activity, the type of violence, the declaration and the declaration if necessary, the response and management of this violence. The data collected was analyzed using Epi info version 7 software. Results: Of the 159 sWs that counted the association, 108 had been included. The average age was 27.0 years with extremes of 14 and 46 years. The age groups of 25 to 34 years were the most represented (43.5%). Fifty-six sWs (51.9%) had reached the secondary level. Unemployed.s.s were in the majority at 74.1%;sixty-six (66) sWs in our sample (61.1%) had already been victims of violence during the exercise of their activity sexual violence was the most represented (28.5%) followed by verbal violence (22.4%). sixty-eight (62.9%) wanted to stop the professional activity of sWs and 93.1% would accept another income-generating activity in place of sex work. Conclusion: It is necessary to supervise sWs and protect them within the framework of respect for human rights, rather than criminalizing them and the exploit

关键词： Female sex Workers Gender-Based Violence Central African Republic

Photometric and.s.ectroscopic study of Ten Low Mass Ratio Contact Binary systems:Orbital stability,O'Connell Effect and Infrared Calcium Line Filling

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Research in Astronomy and Astrophysics 2024年第8期24卷 212-222页

作者： surjit s.Wadhwa Adam Popowicz Raúl Michel Petar Kostić Oliver Vince Nick F.H.Tothill Ain Y.de Horta Miroslav d.Filipović school of science Western Sydney UniversityLocked Bag 1797PenrithNSW 2751Australia department of Electronics Electrical Engineering and MicroelectronicsSilesian University of TechnologyAkademicka 1644120 GliwicePoland Instituto de Astronomía UNAM.A.P.87722800 EnsenadaBCMéxico Astronomical Observatory Volgina 711060 BelgradeSerbia

Low mass ratio contact binary systems are more likely to have unstable orbits and potentially *** addition,such systems exhibit characteristics such as starspots and high energy emissions(UV)suggestive of chromospheric and magnetic *** curve modeling of ten contact binary systems is *** were found to be of extreme low mass ratio ranging from 0.122 to 0.24 and three were found to be potentially unstable and possible merger *** of the infrared calcium absorption lines is a marker of increased chromospheric *** use the available Large sky Area Multi-Object Fiber spectroscopic Telescope spectra along with matched.s.andard.s.ectra(broadened for rotation)to measure the excess filling of the central core depression flux of the two main infrared calcium absorption linesλ8542 andλ*** find that all reported contact binaries have excess filling of the core flux in the infrared calcium *** of the systems reported were also observed by the Galaxy Evolution Explorer mission and we find that all three have features of excess ultraviolet emissions further adding evidence for increased chromospheric activity in low mass ratio contact *** of both orbital stability and absorption line filling is dependent on the determination of geometric and absolute parameters from light curve *** an insignificant number of contact binary light curves exhibit the O’Connell effect,usually attributed to *** d.s.uss the inclusion of starspots in light curve solutions and how they influence the geometric and absolute parameters.

关键词： (stars)binaries eclipsing-techniques photometric-stars chromospheres

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Excellent photoluminescence and electrochemical properties of sm^(3+) doped Ca_(2)Mgsi_(2)O_(7) nanophosphor:d.s.lay and electrochemical sensor applications

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Journal of Rare Earths 2024年第6期42卷 1046-1055,I0002页

作者： R.B.Basavaraj K.sureshkumar d.P.Aarti M.B.Madhusudana Reddy G.Nagaraju T.Ramakrishnappa G.R.Navyashree K.R.Venkatesha Babu K.s.Hemalatha department of Physics BMS Institute of Technology and ManagementBangalore560064India department of Chemistry BMS Institute of Technology and ManagementBangalore560064India department of Chemistry School of Applied SciencesREVA UniversityBangalore560064India Energy Materials ResearchLaboratory Department of ChemistrySiddaganga Institute of TechnologyTumakuru57203KarnatakaIndia school of Physical sciences REVA UniversityBangalore560057Indi department of Physics Govt.Science CollegeBengaluru560001India department of Physics Maharani Science College for WomenMaharani Cluster UniversityBengaluru560001India

A series of orange-red light emitting Ca_(2)Mgsi_(2)O_(7):sm^(3+)nanopowders were fabricated via low-cost ecofriendly green combustion technique using Aloe vera gel as *** phase purity of the samples were confirmed by the powder X-ray diffraction(PXRd)*** single-phase tetragonal structure is observed from the PXRd results with no additional impurity *** band gap energy of the fabricated powders was estimated by diffuse reflectance spectra(d.s.and is found to be in the range of 4.01-5.98 eV.A high resolution scanning electron microscope(sEM)was used to study the morphological behaviour of the ***-like structures are observed from the sEM *** particle size was evaluated by transmission electron microscopy(TEM)and is found to be~50 *** interplanar d.s.ance is found to be 0.53 *** properties were systematically studied in *** phosphors are successfully excited at 403 nm NUV light,producing redd.s.-orange characteristic *** emission peaks are centered at 558(^(4)G_(5/2)→^(6)H_(5/2)),607(^(4)G_(5/2)→^(6)H_(7/2))and 645 nm(^(4)G_(5/2)→^(6)H_(9/2)),*** the observed peaks the red emanation(^(4)G_(5/2)→^(6)H_(7/2))is stronger than the orange emission(^(4)G_(5/2)→^(6)H_(5/2))in the current *** photoluminescent concentration quenching is noticed above 5 mol%sm^(3+)ion doping *** dipole-dipole interaction resulting in cross relaxation is found to be the principal cause of concentration quenching *** color features such as Commission Internationale de I’Eclairage(CIE)and correlated color temperature(CCT)were studied in *** optimized chromaticity coordinates were estimated to be(0.6363,0.3632),which fall in the redd.s.-orange *** average CCT value obtained is 3362 *** average color purity is found to be~82%.sm^(3+)incorporated Ca_(2)Mgsi_(2)O_(7) samples are possible contender for single white light generation commercial candidates owing to

关键词： Green combustion Photoluminescence Orange-red emission Color purity sensors Rare earths

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Connecting cellular mechanisms and extracellular vesicle cargo in traumatic brain injury

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Neural Regeneration Research 2024年第10期19卷 2119-2131页

作者： Nikita Ollen-Bittle Austyn d.Roseborough Wenxuan Wang Jeng-liang d.Wu shawn N.Whitehead department of Anatomy and Cell Biology Western UniversityLondonONCanada schulich school of Medicine and dentistry Western UniversityLondonONCanada deparment of Clinical Neurological sciences Western UniversityLondonONCanada

Traumatic brain injury is followed by a cascade of dynamic and complex events occurring at the cellular level. These events include: diffuse axonal injury, neuronal cell death, blood-brain barrier break down, glial activation and neuroinflammation, edema, ischemia, vascular injury, energy failure, and peripheral immune cell infiltration. The timing of these events post injury has been linked to injury severity and functional outcome. Extracellular vesicles are membrane bound.s.cretory vesicles that contain markers and cargo pertaining to their cell of origin and can cross the blood-brain barrier. These qualities make extracellular vesicles intriguing candidates for a liquid biopsy into the pathophysiologic changes occurring at the cellular level post traumatic brain injury. Herein, we review the most commonly reported cargo changes in extracellular vesicles from clinical traumatic brain injury samples. We then use knowledge from animal and in vitro models to help infer what these changes may indicate regrading cellular responses post traumatic brain injury. Future research should prioritize labeling extracellular vesicles with markers for d.s.inct cell types across a range of timepoints post traumatic brain injury.

关键词： axonal injury biomarkers blood-brain barrier chronic traumatic encephalopathy extracellular vesicles glial activation neuroinflammation traumatic brain injury

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Localized.s.ates quantum confinement induced by roughness in CdMnTe/CdTe heterostructures grown on si(111) substrates

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Journal of semiconductors 2024年第9期 34-42页

作者： Leonarde do Nascimento Rodrigues Wesley Fiorio lnoch Marcos L.F.Gomes Odilon d.d.Couto Jr. Bráulio s.Archanjo sukarno Olavo Ferreira Physics department Federal University of Vi?osa Instituto de Física Gleb Wataghin Universidade Estadual de Campinas National Institute of Metrology Quality and Technology (Inmetro) Materials Metrology Division (DIMAT)

This work shows that d.s.ite a lattice mismatch of almost 20%, CdMnTe/CdTe/CdMnTe heterostructures grown directly on si(111) have surprisingly good optical emission properties. The investigated.s.ructures were grown by molecular beam epitaxy and characterized by scanning transmission electron microscopy, macro-and micro-photoluminescence. Low temperature macro-photoluminescence experiments indicate three emission bands which depend on the CdTe layer thickness and have different confinement characteristics. Temperature measurements reveal that the lower energy emission band (at 1.48 eV)is associated to defects and bound exciton states, while the main emission at 1.61 eV has a weak 2d character and the higher energy one at 1.71 eV has a well-defined (zero-dimensional, 0d) 0d nature. Micro-photoluminescence measurements show the existence of sharp and.s.rongly circularly polarized (up to 40%) emission lines which can be related to the presence of Mn in the heterostructure. This result opens the possibility of producing photon sources with the typical spin control of the diluted magnetic semiconductors using the low-cost silicon technology.

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Two-dimensional atomically thin Pt layers on MXenes: The role of electronic effects during catalytic dehydrogenation of ethane and propane

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Nano Research 2024年第3期17卷 1251-1258页

作者： Zhe Li Tobias K.Misicko Fan Yang Xiaopeng Liu Zhenwei Wu Xiaoyang Gao Tao Ma Jeffrey T.Miller daniela s.Mainardi Collin d.Wick Zhenhua Zeng Yang Xiao Yue Wu department of Chemical and Biological Engineering Iowa State University618 Bissell RoadAmesIA 50011USA Institute for Micromanufacturing Louisiana Tech University505 Tech DriveRustonLA 71272USA davidson school of Chemical Engineering Purdue University480 Stadium Mall DriveWest LafayetteIN 47907USA Michigan Center for Materials Characterization University of Michigan2800 Plymouth RdAnn Arbor MI 48109USA College of Engineering and.s.ience Louisiana Tech UniversityRustonLA 71272USA

Atomically thin Pt nanolayers were synthesized on the surface of Mo2TiC2 MXenes and used for the catalytic dehydrogenation of ethane and propane into ethylene and propylene,two important chemicals for the petrochemical *** compared with Pt nanoparticles,the atomically thin Pt nanolayer catalyst showed.s.perior coke-resistance(no deactivation for 24 h),high activity(turnover frequencies(TOFs)of 0.4–1.2 s^(-1)),and.s.lectivity(>95%)toward ethylene and *** unique Pt nanolayer has a similar geometric surface to Pt nanoparticles,enabling the investigations of the electronic effect on the catalytic performance,where the geometric effect is *** is found that the electronic effect plays a critical role in dehydrogenative product selectivity and catalyst *** metal–support interaction is found dependent on the substrate and metal components,providing wide opportunities to explore high-performance MXene-supported metallic catalysts.

关键词： MXene catalysis alkane dehydrogenation nanolayers