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Frontiers of Structural and Civil Engineering 2024年第3期18卷 411-427页

作者： gowtham.padm.nabhan Ganesh Kumar SHANMUGAM Department of Earthquake Engineering Indian Institute of Technology RoorkeeUttarakhand 247667India Geotechnical Engineering Division CSIR-Central Building Research Institute Academy of Scientific and Innovative Research(AcSIR)Uttarakhand 247667India

The use of prefabricated vertical drains(PVD)in liquefiable deposits is gaining attention due to enhanced ***,investigations on PVD in mitigating re-liquefaction during repeated shaking events are not *** study performed a series of shaking table experiments on untreated and PVD-treated specimens prepared with 40%and 60%relative *** sinusoidal loading was applied with an incremental peak acceleration of 0.1g,0.2g,0.3g,and 0.4g,at 5 Hz shaking frequency with 40 s *** performance of treated ground was evaluated based on the generation and dissipation of excess pore water pressure(EPWP),induced sand densification,subsidence,and cyclic stress *** addition,the strain accumulated in fresh and exhumed PVD was investigated using geotextile tensile testing apparatus aided with digital image *** evidence of pore pressure was reported up to 0.2g peak acceleration for 40%and 60%relative density *** continuous occurrence of soil densification and drainage medium restrained and delayed the generation of EPWP and expedited the dissipation *** study demonstrates PVD can mitigate re-liquefaction,without suffering from deterioration,when subjected to medium to high intense repeated shaking events.

关键词： prefabricated vertical drains drainage re-liquefaction shaking table digital image correlation

Experimental studies on liquefaction and reliquefaction potential of saturated ground subjected to repeated incremental acceleration loading with varying shaking duration

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Earthquake Engineering and Engineering Vibration 2023年第4期22卷 909-920页

作者： gowtham.padm.nabhan Ganesh Kumar Shanmugam Department of Earthquake Engineering Indian Institute of Technology RoorkeeRoorkeeUttarakhand 247667India Geotechnical Engineering Division CSIR-Central Building Research InstituteAcademy of Scientific and Innovative Research(AcSIR)RoorkeeUttarakhand 247667India

Past research has focused on the factors that influence liquefaction under normal shaking ***,studies on parameters that influence the reliquefaction potential of saturated deposits during repeated shaking events are *** this study,an attempt has been made to examine the influence of acceleration amplitude and shaking duration on liquefaction and reliquefaction potential under repeated shaking conditions is conducted.1-g uni-axial shaking table experiments were performed on saturated ground prepared with 40%and 60%relative *** prepared ground was subjected to alternate longer and shorter shaking durations(40 and 20 s)of repeated incremental 0.1 g,0.2 g,0.3 g and 0.4 g acceleration loading,*** variation in density,excess pore water pressure(EPWP),cyclic resistance ratio(CRR)and surface settlement were *** results showed that due to repeated incremental shaking events,reliquefaction was observed on the prepared *** longer shaking duration,the post-liquefied soil showed density improvement with improved soil ***,the application of shorter duration loading followed by longer shaking reduced the beneficial effect of density improvement by disturbing the densified *** to this,the ground was found to be more susceptible to reliquefaction in the subsequent incremental longer shaking event.

关键词： 1g–shaking table reliquefaction acceleration amplitude shaking duration relative density

A digital assistant for shading paper sketches

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Visual Computing for Industry,Biomedicine,and Art 2020年第1期3卷 152-167页

作者： Amal Dev Parakkat Hari Hara gowtham Sarang Joshi Ramanathan Muthuganapathy Indian Institute of Technology Madras Chennai 600036India Indian Institute of Technology Guwahati Assam 781039India

We present a mixed reality-based assistive system for shading paper *** a paper sketch made by an artist,our interface helps inexperienced users to shade it ***,using a simple Delaunaytriangulation based inflation algorithm,an approximate depth map is *** system then highlights areas(to assist shading)based on a rendering of the 2.5-dimensional inflated model of the input *** the help of a mixed reality system,we project the highlighted areas back to aid *** hints given by the system are used for shading and are smudged appropriately to apply an artistic shading to the *** user is given flexibility at various levels to simulate conditions such as height and light *** show that the proposed system aids novice users in creating sketches with impressive shading.

关键词： Shading Paper sketch Mixed reality Iso-contours Delaunay triangulation Digital art

Design, Thermodynamic Performance Comparison and Cost Analysis of Photovoltaic (PV), Concentrated Solar Power (CSP), Wind Turbine, Natural Gas Combined Cycle (NGCC), and Integrated Solar Combined Cycle (ISCC) Power Plants

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Energy and Power Engineering 2020年第6期12卷 288-313页

作者： Peter Jenkins gowtham Ramamoorthy Department of Mechanical Engineering University of Colorado Denver USA

This paper evaluates and discusses ways to use five energy resources more efficiently for generating electric power. An analysis of five different 10 MW powerplants was made: a photovoltaic system, a concentrated solar power system, wind turbines, a natural gas combined cycle and an integrated solar combined cycle. Also, each power plant’s operating principle, thermodynamic analysis, economic analysis, and simulation evaluation were made using the System Advisor Model (SAM), Engineering Equation Solver (EES), and the Thermoflow Power Plant Simulation program. From the analysis, the power plant capacity factor, grid availability, levelized cost of electricity, and annual energy production are compared and analyzed to determine a suitable power plant for a given location.

关键词： Renewable Energy PV CSP Wind Turbine NGCC ISCC

Solar Desalination with Latent Heat Storage Materials and Solar Collector

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Journal of Mechanics Engineering and Automation 2011年第2期1卷 126-134页

作者： gowtham Mohan Hari Narayanan Soundararajan Department of Mechanical Engineering Thiagarajar College of Engineering Madurai Tamil Nadu 625015 India

Availability of clean water is going to become one of biggest demands of the country. Even though there arc various technologies available for purification of water harnessing solar energy fits the purpose for future problems. Distillation is one of many processes available for water purification, and solar energy is one of several forms of heat energy that can be used to energize this process. In this review a study is made to enhance the productivity of the solar stills by connecting solar still with latent heat storage and solar air heater in series and other factors like improving evaporation rate by maintaining Low depth, more exposure area, heat addition by solar collector and presence of latent heat storage material, which is a paraffin wax as a integral part of still. Latent heat storage is one of the most efficient ways of storing thermal energy. Unlike the sensible heat storage method, the latent heat storage method provides much higher storage density, with a smaller temperature difference between storing and releasing heat. Further augmentation of the yield by scraps, pebble, and sand are added.

关键词： Distillation latent heat storage solar still paraffin wax solar collector.

Multidimensional QSAR Modeling of Amprenavir Derivatives as HIV-Protease Inhibitors

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Open Journal of Medicinal Chemistry 2011年第1期1卷 1-15页

作者： Sonal Dubey G. gowtham KLE University"s College of Pharmacy

A computational study has been performed on a series of 55 compounds having (S)-N-(3-(N-(cyclopean- tylmethyl)substituted-phenylsulfonamido)-2-hydroxypropyl)acetamide backbone as HIV-1 protease inhibitors. Various combinations of these specific inhibitors fragments were formed by breaking them at central alicyclic single bonds, while retaining the core. Standard Topomer 3D models were automatically constructed for each fragment, and a set of steric and electrostatic fields was generated for each set of topomers. The models generated showed r2 of 0.811 and crossvalidated r2 (q2) of 0.608. The other method used were Quasar and Raptor based on receptor-modelling concept (6D-QSAR) and this explicitly allows for the simulation of the induced fit, that yielded r2 of 0.574, cross-validated r2 (q2) of 0.504 and predictive r2 (q2) of 0.895 averaged over 200 models. This study has suggested the various type of substituent that can be attached to the core. The information obtained from these 3-D contour maps can be used for the design of amprenavir analogs possessing better protease inhibitory activity.

关键词： 3D-QSAR 5D-QSAR 6D-QSAR Topmer CoMFA Quasar Raptor

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极地船舶结构设计思考

中国舰船研究 2022年第5期17卷 212-219页

作者： Bernt J.LEIRA 柴威 gowtham RADHAKRISNAN 挪威科技大学海洋技术系挪威特隆赫姆7491 武汉理工大学船海与能源动力工程学院湖北武汉430063

冰脊和冰山与极地船体发生碰撞将影响船体结构安全,并决定船体结构设计载荷。船体结构设计应遵循基于风险的设计原则,通常涉及以下极限状态设计准则:1)服务极限状态(SLS);2)最终极限状态(ULS);3)疲劳极限状态(FLS);4)事故极限状态(ALS)... 详细信息

冰脊和冰山与极地船体发生碰撞将影响船体结构安全,并决定船体结构设计载荷。船体结构设计应遵循基于风险的设计原则,通常涉及以下极限状态设计准则:1)服务极限状态(SLS);2)最终极限状态(ULS);3)疲劳极限状态(FLS);4)事故极限状态(ALS)。最终极限状态和事故极限状态对应于发生概率极低的船与冰脊作用以及冰山撞击事件,旨在确保船体结构不会完全损毁。然而,对于较低概率水平的冰载荷分析,需进行较大数据量的工况分析,计算耗时无法承受。为此,引入环境等值轮廓方法,来大幅减少冰载荷分析所需工况数量,并给出设计工况最有可能的冰体参数组合方式。结合最终极限状态和事故极限状态,举例说明这一方法的运用方式。环境等值轮廓方法可为现有极地船舶船体结构设计方法提供有效补充。

关键词：极地船舶船–冰作用环境等值轮廓法船舶结构设计冰载荷

TiNiHf/SiO_(2)/Si shape memory film composites for bidirectional micro actuation

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International Journal of Smart and Nano Materials 2022年第2期13卷 293-314页

作者： Sabrina M.Curtis Marian Sielenkamper gowtham Arivanandhan Duygu Dengiz Zixiong Li Justin Jetter Lisa Hanke Lars Bumke Eckhard Quandt Stephan Wulfinghoff Manfred Kohl Institute for Materials Science Kiel University(CAU)KielGermany Materials Science and Engineering University of MarylandCollege ParkMDUnited States Institute of Microstructure Technology Karlsruhe Institute of Technology(KIT)KarlsruheGermany

The martensitic phase transformation in Ti_(40.4)Ni_(48)Hf_(11.6) shape memory alloys is leveraged for bi-directional actuation with TiNiHf/SiO_(2)/Si *** shape memory properties of magnetron sputtered Ti_(40.4)Ni_(48)Hf_(11.6) films annealed at 635℃-5 min are influenced by film thickness and the underlying *** TiNiHf film thick-ness from 21μm to 110 nm results in the reduction of all characteristic transformation temperatures until a critical thickness is ***,Ti_(40.4)Ni_(48)Hf_(11.6) thin films as low as 220 nm show transfor-mations above room temperature when deposited on SiO_(2) buffer layer,which is of great interest in *** comparison,220 nm films on Si substrates are austenitic at room temperature,and thus not suitable for *** fatigue tests on TiNiHf/SiO_(2)/Si bimorphs demonstrate better functional fatigue characteristics than freestanding films,with an average reduction of 15℃ after 125 cycles,with tempera-ture stabilization *** bi-directional actuation results are promising in the development of bistable actuators within a PMMA/TiNiHf/Si trimorph composite,whereby the additional PMMA layer undergoes a glass transition at 105℃.With the aid of constitutive modeling,a route is elaborated on how bistable actuation can be achieved at micro-to nanoscales by showing favorable thickness combinations of PMMA/TiNiHf/Si composite.

关键词： Bimorph microactuator NiTiHf bistable actuator shape memory alloy thin films

Investigation of FOXP3 (rs3761548) polymorphism with the risk of preeclampsia and recurrent spontaneous abortion: A systemic review and meta-analysis

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Asian pacific Journal of Reproduction 2022年第3期11卷 117-124页

作者： Govinda Sri Varshini Sivakumar Harshini Muhammed Ali Siham Govindaraj Krishnamurthy Tejaswini Yasam Santhosh Kumar Langeswaran Kulanthaivel gowtham Kumar Subbaraj Faculty of Allied Health Sciences Chettinad Hospital and Research InstituteChettinad Academy of Research and Education(Deemed to be University)KelambakkamTamil Nadu 603103India Department of Bioinformatics Alagappa UniversityKaraikudi-630003Tamil NaduIndia

Objective:To investigate the association between forkhead box P3(FOXP3)(rs3761548)polymorphism and the risk of preeclampsia and recurrent spontaneous ***:Literature on the association of FOXP3 gene polymorphisms and susceptibility to preeclampsia and unexplained recurrent spontaneous abortion was retrieved by searching databases such as PubMed,Science Direct,Google Scholar and Embase from 2000 to *** association measure was analyzed using an odds ratio(OR)and 95%confidence interval(CI).All the statistical analyses were executed using RevMan 5.4 ***:In the present meta-analysis,11 articles were *** pooled results showed no association between FOXP3 gene polymorphism(rs3761548)and preeclampsia risk in allelic,recessive,dominant and over dominant contrast ***3 gene polymorphism(rs3761548)showed an association with recurrent abortion in allelic,recessive and dominant models(OR 1.85,CI 1.59-2.14;OR 2.02,95%CI 1.56-2.62;OR 2.69,95%CI 1.50-4.83,respectively),while no association in the over dominant contrast model(OR 1.35,CI 0.87-2.10).Conclusions:In the present study,FOXP3 gene(rs3761548)polymorphism is associated with risk of recurrent spontaneous abortion but not ***,larger sample size and multiracial studies are needed in the future to confirm the findings.

关键词： Preeclampsia FOXP3 gene Single nucleotide polymorphism rs3761548 Unexplained recurrent spontaneous abortion

A case on hemiballismus due to uncontrolled diabetes

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Journal of Acute Disease 2019年第2期8卷 84-85页

作者： Mandla gowtham Chandrasekar Supriya Dudekula Seetharambabu Gopineni Divya Sri padmavathi School of Pharmacy Vyshnavi NagarMohan GardensTiruchanoorTirupati ***India

Uncontrolled diabetes gives rise to severe systemic complications that affect different systems of our body. Among those complications, hemiballismus is a rare manifestation that occurs due to hyperglycemia and can be reversible in most cases by decreasing elevated sugar levels to normal range. Here, we present a case of a patient with diabetic history since 10 years ago, who presented with uncontrolled jerky movements on one side of his body since 15 d, and he recovered after appropriate therapy. Medication adherence in diabetic patients and regular monitoring of blood sugar levels are important.

关键词： Hemiballismus Jerking movements Medication adherence Corpus striatum Basal ganglia