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Nonreciprocal generation of Schrodinger cat state induced by topology

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Science China(Physics,Mechanics & Astronomy) 2024年第4期67卷 23-30页

作者： Zi-Hao li li-li Zheng Ying Wu Xin-You lü School of Physics and Institute for Quantum Science and engineering Huazhong University of Science and Technologyand Wuhan Institute of Quantum TechnologyWuhan 430074China Key laboratory of Optoelectronic Chemical Materials and Devices of Ministry of education Jianghan UniversityWuhan 430074China

The Schrodinger cat state produced differently in two directions is anticipated to be a critical quantum resource in quantum information *** exploring the interplay between quantum nonreciprocity and topology in a one-dimensional microcavity array,we obtain the Schrodinger cat state(a pure quantum state)in a chosen direction at the edge cavity,whereas a classical state in the other *** nonreciprocal generation of the cat state originates from the topologically protected chiralitymode excitation in the nontrivial phase,but in the trivial phase,the nonreciprocal generation of cat state ***,our proposal is switchable by tuning the parameters so that a topological phase transition ***,the obtained cat state has nonreciprocal high fidelity,nonclassicality,and quantum coherence,which are sufficient to be used in various one-way quantum technologies,e.g.,invisible quantum sensing,noise-tolerant quantum computing,and chiral quantum *** work provides a general approach to control quantum nonreciprocities with the topological.effect,which substantially broadens the fields of nonreciprocal photonics and topological physics.

关键词： Schr?dinger cat state nonreciprocity topology

A Method for evaluating the Maximum Bending Degree of Flexural Toppling Rock Masses Based on the Rock Tensile Strain-Softening Model

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Journal of earth Science 2024年第4期35卷 1243-1253页

作者： Jiongchao Wang Jun Zheng Jichao Guo Qing lü Jianhui Deng Department of Civil.engineering Zhejiang UniversityHangzhou310058China Center for Balance Architecture Zhejiang UniversityHangzhou310007China State Key laboratory of Hydraulics and Mountain River engineering College of Water Resource and HydropowerSichuan UniversityChengdu610065China

Flexural toppling occurs when a series of layered rock masses bend towards their free *** is important to evaluate the maximum bending degree and the requirement of supports of flexural toppling rock mass to prevent rock mass cracking and even failure leading to a *** on the rock tensile strain-softening model,this study proposes a method for calculating the maximum curvature(C_(ppmax))of flexural toppling rock *** applying this method to calculate Cppmax of 9 types of rock masses with different hardness and rock layer thickness,some conclusions are drawn:(1)the internal key factors affecting C_(ppmax)are e^(⋆)(e^(⋆)=e_(ss)/e_(0),where e_(0)and e_(ss)are the mean deformation moduli of the rock before and after reaching its peak tensile strength,respectively),the strainεt corresponding to the tensile strength of rock,and the thickness(h)of rock layers;(2)hard rock layers are more likely to develop into block toppling than soft rock layers;and(3)thin rock layers are more likely to remain in flexural toppling state than thick rock *** addition,it is found that C_(ppmax)for flexural toppling rock masses composed of bedded rocks such as gneiss is related to the tensile direction.

关键词： flexural toppling rock mass maximum bending degree strain-softening model curvature rock mechanics

Mogroside IIe,an in vivo metabolite of sweet agent,al.eviates acute lung injury via Pla2g2a-eGFR inhibition

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Food Science and Human Well.ess 2024年第1期13卷 299-312页

作者： Weichao lü Guoqing Ren Kuniyoshi Shimizu Renshi li Chaofeng Zhang State Key laboratory of Natural Medicines School of Traditional Chinese PharmacyChina Pharmaceutical UniversityNanjing 211198China Sino-Jan Joint lab of Natural Health Products Research School of Traditional Chinese PharmacyChina Pharmaceutical UniversityNanjing 211198China Faculty of Agriculture Kyushu UniversityFukuoka 819-0395Japan

In the face of increasingly serious environmental pollution,the health of human lung tissues is also facing serious *** IIe(M2e)is the main metabolite of sweetening agents mogrosides from the anti-tussive Chinese herbal Siraitia *** study elucidated the anti-inflammatory action and molecular mechanism of M2e against acute lung injury(AlI).A lipopolysaccharide(lPS)-induced AlI model was established in mice and MH-S cells were employed to explore the protective mechanism of M2e through the western blotting,co-immunoprecipitation,and quantitative real time-PCR *** results indicated that M2e al.eviated lPS-induced lung injury through restraining the activation of secreted phospholipase A2 type IIA(Pla2g2a)-epidermal growth factor receptor(eGFR).The interaction of Pla2g2a and eGFR was identified by *** addition,M2e protected AlI induced with lPS against inflammatory and damage which were significantly dependent upon the downregulation of AKT and m TOR via the inhibition of ***2g2a may represent a potential target for M2e in the improvement of lPS-induced lung injury,which may represent a promising strategy to treat AlI.

关键词： Mogroside IIe Acute lung injury Secreted phospholipase A2 type IIA(Pla2g2a) epidermal growth factor receptor(eGFR)

Artificial intelligence meets body sense: task-driven neural networks reveal computational principles of the proprioceptive pathway

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Signal Transduction and Targeted Therapy 2024年第8期9卷 3147-3149页

作者： leonard e.van Dyck Frank Bremmer Katharina Dobs Department of Psychology Justus Liebig University GiessenGiessenGermany Max Planck Institute for Human Cognitive and Brain Sciences LeipzigGermany Center for Mind Brain and BehaviorUniversities of MarburgGiessenand DarmstadtMarburgGermany Department of Neurophysics Philipps-Universitat MarburgMarburgGermany

In a recent study published in Cell,Marin Vargas and Bisi et al.1 present an innovative approach to unravel the computational principles underlying proprioceptive processing in non-human *** findings showcase the utility of task-driven modeling in advancing neuroscience and offer translational potential by providing seminal insights into the goals and mechanisms by which the brain encodes body position and movements.

关键词： networks neural principles

Consequences of early life stress on the structure and function of the adult mouse retina

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Neural Regeneration Research 2024年第1期19卷 150-151页

作者： Juan S.Calanni Ruth e.Rosenstein laboratory of Retinal Neurochemistry and experimental Ophthalmology Department of Human BiochemistrySchool of Medicine/CEFyBOUniversity of Buenos Aires/CONICETBuenos AiresArgentina

early-life stress(elS)refers to a period of environmental/social deprivation,physica l,sexual or emotional abuse,neglect,severe and/or chronic trauma in the prenatal.early postnatal stage,which is closely related to many adverse psychiatric disorders later in life,such as depressive disorder,substance abuse,dysthymia,panic,anxiety,and suicidal behavior in adulthood(Waters and Gould,2022).

关键词： stress life Gould

Item-level Analysis of the Revised Occupational Therapy Fieldwork Performance evaluation Appl.ed in Practice

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Open Journal of Therapy and Rehabilitation 2024年第2期12卷 145-159页

作者： Cynthia l. Sears Brad e. egan Patricia F. Tomsic Craig A. Velozo Graduate Col.ege of Health Professions Occupational Therapy Program Hawai&#8217i Pacific University Honolulu HI USA Col.ege of Science and Health Occupational Therapy Program DePaul University Chicago IL USA Department of Occupational Therapy Wingate University Wingate NC USA Col.ege of Health Professions Department of Rehabilitation Sciences Division of Occupational Therapy Medical University of South Carolina Charleston SC USA

Competency-based assessments for healthcare professionals are critical for safe and effective cl.ent outcomes. Rehabilitation clinical skill competency assessments must be validated and revised to produce safe and skil.ed practitioners. The revised American Occupational Therapy Association (AOTA) Fieldwork Performance evaluation (FWPe) instrument measures occupational therapy student performance to determine readiness for practice. The assessment includes thirty-seven competencies that address both profession specific clinical skills and general professional behavior skills. The objective of this study was to use Rasch methods to explore the use of the revised FWPe in actual fieldwork practice and to determine the instrument’s psychometric properties when separating the item components into two distinct subdomains: General Health Professions Competences and Occupational Therapy-Specific Competencies. Internal construct validity and test reliability were analyzed using data from 149 occupational therapy students after completing their initial level II A fieldwork clinical internship. This study examined the item difficulty hierarchy, item fit, person-fit to model, person separation index, person separation reliability coefficient, strata, ceiling and floor effect, and unidimensionality of the FWPe instrument as a whole and as two separate domains. With the exception of not meeting the criteria for unidimensionality, the full FWPe instrument and the Occupational Therapy-Specific Competencies subdomain showed acceptable item-level psychometrics for reliability and precision. While the General Health Professions Competencies subdomain showed good item-level psychometrics, it was below the criterion for reliability and only separated the sample into two strata. Results support the validity, reliability, and clinical use of the revised FWPe full instrument and the Occupational Therapy-Specific Competencies subdomain to measure entry-level clinical skill competencies in pr

关键词： Rehabilitation Competency-Based Assessments Occupational Therapy Measurement Rasch Analysis

In search of a pan-coronavirus vaccine:next-generation vaccine design and immune mechanisms

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Cellular & Molecular Immunology 2024年第2期21卷 103-118页

作者： S.Cankat M.U.Demael l.Swadling Division of Infection and Immunity Institute of Immunity and TransplantationUniversity College LondonPears BuildingLondon NW32PPUK

Members of the coronaviridae family are endemic to human populations and have caused several.epidemics and pandemics in recent *** this review,we will discuss the feasibility of and progress toward the ultimate goal of creating a pan-coronavirus vaccine that can protect against infection and disease by all members of the coronavirus *** will detail the unmet clinical need associated with the continued transmission of SARS-CoV-2,MeRS-CoV and the four seasonal coronaviruses(HCoV-OC43,Nl63,HKU1 and 229e)in humans and the potential for future zoonotic *** will highlight how first-generation SARS-CoV-2 vaccines and natural history studies have greatly increased our understanding of effective antiviral immunity to coronaviruses and have informed next-generation vaccine *** will then consider the ideal properties of a pan-coronavirus vaccine and propose a bl.eprint for the type of immunity that may offer ***,we will describe a subset of the diverse technologies and novel approaches being pursued with the goal of developing broadly or universally protective vaccines for coronaviruses.

关键词： Vaccine Coronavirus Cross-reactive immunity Cross-protection Universal

Study on the dynamic mechanical properties of winding-block axial structure considering short circuit strain rate effect

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High Voltage 2024年第2期9卷 380-390页

作者： Xinyu Wang Ping Wang Jianghai Geng Zikang Zhang Fangcheng lü Shuguo Gao Hebei Provincial Key laboratory of Power Transmission equipment Security Defense North China Electric Power UniversityBaodingChina State Grid Hebei electric Power Research Institute ShijiazhuangChina

Transformers may suffer multiple short-circuit impacts during long-term operation,and axial instability is one of the typical types of serious accidents caused by short-circuit *** axial instability form of the winding-block structure is analysed,and the dynamic solution of the winding short-circuit electromagnetic force is obtained by estab-lishing the three-dimensional magnetic-circuit-force multi-physical field coupling simulation *** infl.ence of strain rate on the cushion block constitutive equation is corrected,and the modified model is verified by short-circuit impact test and quasi-static *** research results show that for 110 kV 31.5 MVA transformers,the maximum electromagnetic axial resultant force of winding is 363.16 kN,and the ultimate tilt force is 1214.2 *** pre-tightening force configuration is accordingly recom-mended to range from 363.16 to 608.28 kN,which is narrowed by 18.49%compared with the static calculation method;Meanwhile,adding a logarithmic strain rate correction term to the classical constitutive equation of the cushion block can achieve a good correction of the stress-strain relationship with the coefficient of determination above 0.99,and the cushion block has a larger elastic modulus under high strain rate *** research results provide an important theoretical reference for the axial stability structure of transformers.

关键词： axial correction structure

evaluation of Growth Rate of Invasive Aquatic Macrophytes and Contribution to Its Use in Organic Fertilizer Production: A Case of eicchornia crassipes (Mart.) Solms, 1883 in the lobé Creek (littoral-Cameroon)

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Open Journal of ecology 2024年第7期14卷 571-583页

作者： Roland Didier Nwamo gordon Nwutih Ajonina Tapite Chanel Yamkou Kopmou Thomas efole ewoukem Minette Tomedi eyango Department of Aquatic ecosystems Management Institute of Fisheries and Aquatic Sciences at Yabassi University of Douala Douala Cameroon Cameroon Wildlife Conservation Society Mangrove & Coastal Wetlands Research Centre Mouanko Cameroon Department of Forestry Faculty of Agronomy and Agricultural Sciences University of Dschang Dschang Cameroon Department of Aquaculture Institute of Fisheries and Aquatic Sciences at Yabassi University of Douala Douala Cameroon

From 20 January to 20 July 2023, a study was carried out on the lobé Creek, a waterway subject to considerable natural and man-made pressures, with a negative impact on its biodiversity and habitats. The aim was to evaluate the growth rate of invasive aquatic macrophytes and their contribution to the use of organic fertilisers: a case of eicchornia crassipes (Mart.) Solms, 1883 in the lobé Creek (littoral-Cameroon) with a view to its appropriate use in agronomy. The specific objective was to examine the impact of anthropogenic actions on lobé Creek, characterise physico-chemical.environment of the study area, and evaluate the growth rate of e. crassipes and its chemical composition with a view to producing an organic biofertiliser. The results show that e. crassipes represents a considerable threat to the populations of these localities. As for the physico-chemical parameters, the temperature val.es vary from 24 ± 1.41˚C to 26.5 ± 1.13˚C;pH from 6.3 ± 0.1 to 7.2 ± 0.07;conductivity and dissol.ed oxygen vary respectively from 40.7 ± 1.83 µS/cm to 19.6 ± 3.11 µS/cm and from 7.3 ± 0.14 mg/l to 5.8 ± 1.55 mg/l. Its average growth rate varies from 0.69 feet/day to 0.63 feet/day. With regard to the nitrogen, phosphorus and potassium content of water hyacinth plants, the results show that the average total nitrogen content ranges from 6.11 ± 1.59 g/kg to 5.2 ± 2.03 g/kg;total phosphorus, from 0.52 ± 0.54 g/kg to 0.88 ± 0.38 g/kg;and potassium, from 1.43 ± 0.45 g/kg to 2.61 ± 0.89 g/kg.

关键词： eichhornia crassipes lobé Creek Anthropogenic Actions Physico-Chemical.environment Growth Rate Chemical Composition