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Physico-Chemical and Nutritional Properties of a Food Broth Based on Nere (Parkia biglobosa)

Food and Nutrition Sciences 2024年第5期15卷 377-389页

作者： Lassana Bamba Gervais Melaine M’Boh N’Gbésso Amos Ekissi Kipré Laurent Séri gnogbo alexis.bahi Koffi Pierre Valery Niaba Allico Joseph Djaman Grah Avit Maxwell Beugre Laboratory of Agro-Valorization Department of Agroforesterie Jean Lorougnon Gu&#233d&#233 University Daloa C&#244te d&#8217Ivoire Medical and Fundamental Biochemistry Department Institut Pasteur of C&#244te d&#8217Ivoire Abidjan C&#244te d&#8217Ivoire Laboratory of Biotechnology Agriculture and Valorization of Biological Resources Department of Biosciences Felix Houphouet-Boigny University Abidjan Cote d&#8217Ivoire Biology and Health Laboratory Department of Biosciences Felix Houphouet-Boigny University Abidjan C&#244te d&#8217Ivoire

Purpose: Diet and eating habits are major risk factors for the health and the development of disease, such as, for example, metabolic disorder leading to cardiovascular pathology and cancer, decreased immunity exposing to infections. This study of the physico-chemical and nutritional properties of a soumara-based food broth was carried out with the aim of promoting the consumption of organic broth made from nere seeds (soumara). That is to alleviate certain metabolic diseases, which is a matter of food safety, and also to limit the risk for the health about the consumption of some cooking stocks on the market. Methods: Several natural ingredients such as nere seeds (soumara), ginger, black pepper, parsley and garlic were used to create a nere-based stock. All these ingredients were freeze-dried and the powder obtained was used to make the broth, regarding their physical and chemical properties. Results: The broth had a good protein content of 17.41 ± 0.367 g/100g, a lipid content of 16.80 ± 0.08 g/100g and a fiber content of 8.66 ± 0.04 g/100g. In terms of nutritional values, the broth showed good levels of calcium 184.21 ± 0.09 mg/100g, potassium 50.04 ± 1.45 mg/100g and iron and zinc. In terms of antioxidant activity, the broth also showed good antioxidant activity. Conclusion: Regarding the properties of our food broth, whose composition is based on natural ingredients, could be recommended for consumption and, its properties, could play an important role in preventing and combating certain metabolic diseases.

关键词： Food Broth Nere Physico-Chemical Properties Nutrition Food Safety

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Persistently High Glycated Hemoglobin in a Subgroup of Type 2 Diabetic Patients Who Failed Usual Oral Antihyperglycemics and Insulin in Côte d’Ivoire

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Advances in Biological Chemistry 2023年第3期13卷 100-109页

作者： Louise Odile Moke-Bedji Assieoussou Jean-Luc N’Guessan Lydie Boyvin Colombe Lohore gnogbo alexis.bahi Allico Joseph Djaman Amos Ankotche Diabetes and Hypertension Clinic Treichville University Hospital Abidjan C&#244te d’Ivoire Faculty of Biosciences Felix Houphou&#235t-Boigny University (UFHB) Abidjan C&#244te d’Ivoire Department of Fundamental and Medical Biochemistry Institute Pasteur of C&#244te d’Ivoire (IPCI) Abidjan C&#244te d’Ivoire

Background: Type II diabetes mellitus is associated with multiple metabolic derangements which can cause secondary pathophysiological changes in multiple organ systems. This in turn can impose a heavy burden of morbidity and mortality from micro‑ and macro‑vascular complications. This study aimed to describe the metabolic and therapeutic profile of a subgroup of type 2 diabetic patients who have treatment failure with oral anti-hyperglycemic agents with persistent hyperglycemia despite insulin treatment. Methods: 60 type 2 diabetic patients in treatment failure with oral antidiabetics and under insulin treatment, aged 35 to 70 years, were recruited at the Diabetes Clinic of the University Teaching Hospital of Treichville in Abidjan, Côte d’Ivoire. Blood samples were collected in tubes containing Ethylenediaminetetraacetic Acid (EDTA) to determine glycated hemoglobin (HbA1c). Results: The average age of the population was 54 ± 9.38 years with a sex ratio (M/F) of 0.3, an average BMI of 30.25 ± 5 kg/m2, and an average HbA1c of 10.1% ± 1.6% for an average diabetes duration of 11.8 ± 5.8 years. The average insulin dose was 74.556 ± 16.21 UI/day, and the average duration of insulin treatment was 5.4 ± 3.1 years. The average HbA1c value was 10.1% ± 1.87% in men against 10.03% ± 1.53% in women with no significant difference (p = 0.1). The mean HbA1c values according to patient weight were 10.08% ± 2.05% for normal weight, 9.55% ± 2.26% for overweight, and 10.57% for obese, with no significant difference between the three groups of patients (p = 0.1). Conclusion: This study showed a persistence increase in glycated hemoglobin regardless of the treatment regimen, duration, and dose of insulin treatment in the subpopulation of type 2 diabetic patients.

关键词： High Glycated Hemoglobin Type 2 Diabetic Insulin Côte d’Ivoire

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Vitamin D and Parathyroid Hormone Profiles in Living Kidney Failure Patients in Côte d’Ivoire

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Advances in Biological Chemistry 2022年第2期12卷 39-47页

作者： Maxime Roméo Kouadio Lydie Boyvin gnogbo alexis.bahi Assieoussou Jean-Luc N’Guessan Cackouoh Carole Constance Koudou Souleymane Méité Allico Joseph Djaman Department of Clinical and Fundamental Biochemistry Institute Pasteur of C&ocirc te d’Ivoire (IPCI) Abidjan C&ocirc te d’Ivoire Health Biology Laboratory University Félix Houphou&euml t-Boigny (UFHB) Abidjan C&ocirc te d’Ivoire

Introduction: Abnormalities in mineral and bone metabolism, particularly phosphocalcic metabolism, are common in renal failure and are associated with a significant morbidity and mortality. The regulation of phosphocalcic metabolism is subject to a particularly precise and complex control of parathormone (PTH) and vitamin D. Assessment of vitamin D and parathyroid hormone concentrations would help to improve the medical management of patients with chronic kidney disease and ensure a better quality of life. Methods: The study population consisted of 138 individuals including 46 non- dialysis renal failure patients, 46 chronic hemodialysis patients and 46 non- renal failure volunteers to serve as controls. Serum Parathyroid hormone and Vitamin D concentrations were measured using the Vidas automated system. Results: 25-hydroxyvitamin D concentrations in controls (65 ± 2.41 nmol/L) and dialysis patients (70 ± 3.03 nmol/L) were significantly higher than those in CKD patients (48 ± 3.34 nmol/L). On the other hand, the mean values of Parathyroid hormone in dialysis patients (312 ± 36.22 pg/mL) and CKD patients (117 ± 10.68 pg/mL) were very high compared to that in controls (25 ± 2.34 pg/mL). Conclusion: Secondary hyperparathyroidism is common in renal failure. Parathyroid hormone and 25-hydroxyvitamin D assays would be adequate for better management of chronic renal failure.

关键词： 25-Hydroxyvitamin D Chronic Renal Failure Côte d’Ivoire Secondary Hyperparathyroidism Parathyroid Hormone

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SARS-CoV-2 Infection Is Associated with Vitamin D Deficiency in Côte d’Ivoire

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Advances in Microbiology 2022年第2期12卷 43-52页

作者： Lydie Boyvin Yapi Guillaume Yayé gnogbo alexis.bahi Aya Jeanne Armande Aké Kipré Laurent Séri Daouda Sévédé Serge Eholié Mireille Dosso Allico Joseph Djaman Department of Fundamental & Medical Biochemistry Institut Pasteur of C&ocirc te d’Ivoire (IPCI) Abidjan C&ocirc te d’Ivoire Biology and Health Laboratory University Félix Houphou&euml t-Boygny (UFHB) Abidjan C&ocirc te d’Ivoire Department of Biochemistry-Microbiology University of Jean Lorougnon Guédé Daloa C&ocirc te d’Ivoire Department of Bacteriology-Virology Institut Pasteur of C&ocirc te d’Ivoire (IPCI) Abidjan C&ocirc te d’Ivoire Department of Infectious Diseases of the Treichville University Hospital Center Abidjan C&ocirc te d’Ivoire

In 2019, the coronavirus pandemic broke out as a serious public health issue worldwide. In Côte d’Ivoire, the number of cases of COVID-19 has increased rapidly. The Severe Acute Respiratory Syndrome virus (SARS-CoV-2) binds to angiotensin converting enzyme 2 (ACE2) receptors in the respiratory tracts and enters the respiratory and alveolar cells of infected patients. Deficiency of fat-soluble vitamin D3 is associated with respiratory distress syndrome and pulmonary fibrosis by activation of the renin-angiotensin system. In Côte d’Ivoire, very little research is being done on SARS-CoV-2 and vitamin D. The objective of this study was to assess the vitamin D status of people infected and suffering from COVID-19 in order to contribute to their medical treatment. The study involved 100 adults infected with SARS-CoV-2 (24 women and 76 men). After confirmation of the patient’s SARS-CoV-2 status by RT-PCR, the 25 (OH) vitamin D assay was performed on the Cobas 6000 device and compared to control subjects, the non-COVID-19 positive. A significant decrease in 25-hydroxy vitamin D3 concentrations (44 ± 1.29 nmole/L) was observed in patients infected with SARS-CoV-2, compared to control (78 ± 0.68 nmole/L) (p 3 deficiency requires vitamin D supplementation in the management of hospitalized patients infected with SARS-CoV-2.

关键词： Côte d’Ivoire SARS-CoV-2 Vitamin D Deficiency

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Nutrient Intake and Impact of the Consumption of Two Street Foods (Garba and Rice Eggplant Sauce) in Humans

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Food and Nutrition Sciences 2022年第3期13卷 195-210页

作者： N’Gbésso Amos Ekissi Yadé Réné Soro gnogbo alexis.bahi Ahou Bénédicte Nina Kouassi N’Guessan Jean-Eugène Parfait Kouadio Kouassi Benjamin Yao Allico Joseph Djaman Laboratory of Biotechnology Agriculture and Valorization of Biological Resources Department Biosciences University Félix Hou-phouet-Boigny Abidjan C&#244 te d’Ivoire Department of Clinical and Fundamental Biochemistry Institute Pasteur in C&#244 te d’Ivoire Abidjan C&#244 te d’Ivoire Laboratory of Biochemistry Microbiology and Valorization of Agricultural Resources Institute of Agropastoral Management Univer-sity Péléforo Gon Coulibaly Korhogo C&#244 te d’Ivoire Department Communication Environment and Society University Alassane Ouattara Bouake C&#244 te d’Ivoire Laboratory of Biocatalysis and Bioprocessing Department of Food Science and Technology University Nangui Abrogoua Abidjan C&#244 te d’Ivoire Laboratory of Industrial Processes Synthesis Environment and New Energies Institute National Polytechnique Felix Houphouet-Boigny Yamoussoukro C&#244 te d’Ivoire

Many lifestyle factors can affect health, but nutrition is an important, modifiable, and powerful factor in promoting health, preventing and treating disease, and improving quality of life. Inadequate dietary intake, regardless of the cause, can have negative effects on human growth and development. Analysis of tuna “Garba” and rice with eggplant sauce consumed in Abidjan (Côte d’Ivoire) revealed low levels of water-soluble B vitamins. Also, the analysis of these dishes observed the presence of histidine, leucine, valine, glutamine, arginine, cysteine and alanine. The tuna “Garba” (Gab) dish showed levels in amino acids ranging from 69.8 ± 1.33 to 764 ± 2.08 mg/kg and 77.1 ± 1.95 to 754.67 ± 2.8 mg/kg in the eggplant sauce rice (Risa) dish. During 15 days of consumption of these dishes by the wistar rats, anthropometric parameters, namely body length and abdominal circumference, showed a significant increase in the rats consuming the rice eggplant sauce. The rats showed BMI, Lee’s Index and Adipocyte Index ranged from 0.27 ± 0.01 to 0.31 ± 0.01 g/cm2;0.25 ± 0.01 to 0.26 ± 0.00 cm and 1.67% ± 0.25% to 1.96% ± 0.21% respectively. The nutritional profiling of these two street foods by LIM and SAIN score presented poor profiles.

关键词： Nutritional Values Tuna Garba Rice Eggplant Sauce Nutritional Profiling Abidjan (Côte d’Ivoire)

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