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Clinical Research Communications 2023年第1期6卷 1-4页

作者： Larissa de Andrade Defendi giuliano ferreira morgantetti Guilherme Alencar de Medeiros Marcelo Balancin Department of Radiology Escola Paulista de MedicinaSão Paulo/SP 04024-002Brazil Department of Dermatopathology NORDD PathologyFortaleza/CE 60140-110Brazil Department of Pathology FOSPOncocentro FoundationSão Paulo/SP 04024-002Brazil

Chromoblastomycosis(CBM)is a fungal disease,distributed in tropical and subtropical regions,affecting mainly rural *** is characterized by chronic skin lesions that may vary from nodular,tumorous,verrucous or plaque *** constitutional symptoms are rarely *** histological presentation may yield a pathognomonic feature,the Medlar(sclerotic)bodies,in which a typical brown to black pigment is depicted,explaining“copper pennies”as its *** this article,the case of a 56-year-old woman in the countryside of Brazil is reported,whose main complaint was a chronic leg ulcer for the past 8 *** left leg had a large,partially ulcerated plaque lesion was *** cultures were positive for the *** analysis demonstrated pseudoepitheliomatous hyperplasia,lymphohistiocytic infiltrate and sclerotic bodies(“copper pennies”).CBM’s epidemiological panorama,once established uniquely by geographical distribution,is transitioning to a global health issue,influenced by immunosuppressive conditions,global warming and *** scenario demands CBM to be widely considered as a differential diagnosis and may represent a clinical challenge in regions whose professionals have little expertise in infectious tropical diseases.

关键词： chromoblastomycosis fungal infection histopathology global health

Robot-assisted endoscopic inguinal lymphadenectomy:A review of current outcomes

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Asian Journal of Urology 2021年第1期8卷 20-26页

作者： Gilberto Jose´Rodrigues giuliano Betoni Guglielmetti Marcelo Orvieto Kulthe Ramesh Seetharam Bhat Vipul R.Patel Rafael ferreira Coelho Sao Paulo State Cancer Institute University of Sao Paulo School of MedicineSao PauloBrazil Clı´nica Alemana SantiagoChile Department of Urology AdventHealth Global Robotics InstituteCelebrationFLUnited States

Objective:To review the role of robot-assisted endoscopic inguinal lymphadenectomy(RAIL)in the management of penile ***:A PubMed search for all relevant publications regarding RAIL series up until August 2019 was performed using the keyword“robotic”,“inguinal lymph node dissection”,and“penile cancer”.Weighted mean was calculated in the largest series for all outcomes using the number of patients included in each study as the weighting ***:We identified 23 articles,of note the three largest series that included 102,27,and 20 RAIL in 51,14,and 10 patients,*** vein was spared in 88.93%of RAIL cases in these series and node yield was 11.42 per groin;35.28%of patients had positive pathological *** weighted mean of operative time was 87.98 min per RAIL and the estimated blood loss was 37.08 mL per *** mean length of hospital stay was 1.29 days and the drain was kept in place for 17.02 days;the major complication rate was only 5.31%in these *** mean follow-up was 33.46 months with a recurrence-free survival of 96.33%.Conclusion:The literature regarding RAIL describes promising results,although it has shorter follow-up and higher costs when compared to historically series from the open *** series reported lower cutaneous complications compared to conventional approach,without compromising oncological ***,long-term results and larger trials are crucial to validate those findings.

关键词： Penile tumor Minimally invasive surgery Robotic-assisted inguinal lymphadenectomy

ENERGY ESTIMATES FOR DELAY DIFFUSION-REACTION EQUATIONS

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Journal of Computational Mathematics 2008年第4期26卷 536-553页

作者： J.A.ferreira P.M.daSilva CMUC-Departamento Departamento

In this paper we consider nonlinear delay diffusion-reaction equations with initial and Dirichlet boundary conditions. The behaviour and the stability of the solution of such initial boundary value problems （IBVPs） are studied using the energy method. Simple numerical methods are considered for the computation of numerical approximations to the solution of the nonlinear IBVPs. Using the discrete energy method we study the stability and convergence of the numerical approximations. Numerical experiments are carried out to illustrate our theoretical results.

关键词： Delay diffusion reaction equation Energy method Stability Convergence.

A Rapid Parameter of Enzyme-Treated Cellulosic Material Revealed by Reducing Sugar Release

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Journal of Renewable Materials 2024年第3期12卷 539-551页

作者： Verônica Távilla ferreira Silva Adriane Maria ferreira Milagres Departamento de Biotecnologia Escola de Engenharia de LorenaUniversidade de São PauloLorenaSP12602-810Brazil

This study was conducted to evaluate the effectiveness of enzymes in purifying and reducing the degree of polymerization of cellulose for the production of dissolving *** goal was to determine the contributions of xylanase(X)and endoglucanase(EG)in the treatment of pulp,specifically by quantifying the formation of soluble and insoluble reducing sugars using the dinitrosalycilic acid(DNS)***,the release of soluble reducing sugars(RSSol)was enhanced after xylanase treatment,while endoglucanase(EG)treatment led to changes in insoluble reducing sugars(RSIns).The maximum synergism was observed for RSIns when a high ratio of endoglucanase to xylanase(320EG:5X/g pulp)was *** relative contribution of endoglucanase to RSins was determined to be 15.6%of the total reducing *** viscosity of pulps treated with xylanase decreased only by 7%,whereas endoglucanase treatment significantly reduced viscosity by 45%.Modifications in the particle size were observed after pulp treatment with the combination of endoglucanase and *** summary,the DNS test is a rapid and effective method for evaluating the efficiency of enzyme treatments on *** measurement of RSIns correlates with changes in pulp viscosity to different extents,providing valuable insights into the effectiveness of enzyme treatments.

关键词： Endoglucanase xylanase cellulose fiber pulp synergism

Analysis of the impact of large scale seismic retrofitting strategies through the application of a vulnerability-based approach on traditional masonry buildings

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Earthquake Engineering and Engineering Vibration 2017年第2期16卷 329-348页

作者： Tiago Miguel ferreira Rui Maio Romeu Vicente ISISE Department of Civil EngineeringUniversity of MinhoCampus de Azurém RISCO Department of Civil EngineeringUniversity of AveiroCampus Universitário de Santiago

The buildings＇ capacity to maintain minimum structural safety levels during natural disasters, such as earthquakes, is recognisably one of the aspects that most influence urban resilience. Moreover, the public investment in risk mitigation strategies is fimdamental, not only to promote social and urban and resilience, but also to limit consequent material, human and environmental losses. Despite the growing awareness of this issue, there is still a vast number of traditional masonry buildings spread throughout many European old city centres that lacks of adequate seismic resistance, requiring therefore urgent retrofitting interventions in order to both reduce their seismic vulnerability and to cope with the increased seismic requirements of recent code standards. Thus, this paper aims at contributing to mitigate the social and economic impacts of earthquake damage scenarios through the development of vulnerability-based comparative analysis of some of the most popularretrofitting techniques applied after the 1998 Azores earthquake. The influence of each technique individually and globally studied resorting to a seismic vulnerability index methodology integrated into a GIS tool and damage and loss scenarios are constructed and critically discussed. Finally, the economic balance resulting from the implementation of that techniques are also examined.

关键词： urban resilience masonry buildings retrofitting strategies vulnerability-based approach loss estimation

The role of culture for coastal disaster risk reduction measures:Empirical evidence from northern and southern Europe

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Advances in Climate Change Research 2020年第4期11卷 297-309页

作者： Grit MARTINEZ Susana COSTAS Oscar ferreira Ecologic Institute Berlin10717Germany Centro de Investigacao Marinha e Ambiental(CIMA) Universidade do AlgarveFaro8005-139Portugal Centro de Investigacao Marinha e Ambiental(CIMA) Faculty of Sciences and TechnologyUniversidade do AlgarveFaro8005-139Portugal

Recent and historic high-impact events have demonstrated significant flood risks to many coastal areas in Europe and across the *** the behavior of humans in relation to risk management poses grand challenges for both natural and social sciences and *** study analyzes the cultural aspects of coastal risk management and illustrates path-dependencies of concrete disaster risk reduction measures in relation to local contexts in European coastal regions in Northern and South Western *** adopts a comparative approach by targeting risk perception and risk management related to coastal floods and erosion,induced by storms and sea level rise,in two contrasting coastal areas:German coastal state SchleswigeHolstein at the Baltic Sea(especially the communities Eckernf€orde and Timmendorfer Strand)and the Portuguese barrier island system of Ria Formosa(especially the community of Faro Beach).Both regions are very low lying with only a few meters above sea level and exposed to similar hazards such as erosion and floods induced by coastal storms,and while they are both attractive touristic destinations,they are culturally,socio-economically and politically very *** geographical and the socio-cultural contexts of the case study regions are assessed first using an explorative approach,followed by an analysis of the relevance of cultural aspects for the implementation of disaster risk reduction *** study addresses both first responders(city authorities,citizens)and *** is found that the choice of risk reduction measures hinges on the values underlying people's perspectives about the desired outcomes of specific measures and that the role of identity and meaning making are still undervalued in decision making *** concludes that subjective capacities formed by cultural identities,knowledge,trust coupled with a variety of factors of socio-economic and political texture are important to understand local decision making

关键词： Culture Values Knowledge Risk perception Disaster risk reduction measures Coastal zones Baltic Sea Atlantic

Communicating with the non-dominant hemisphere:Implications for neurological rehabilitation

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Neural Regeneration Research 2013年第13期8卷 1236-1246页

作者： Fabricio ferreira de Oliveira Sheilla de Medeiros Correia Marin Paulo Henrique ferreira Bertolucci Department of Neurology and Neurosurgery Escola Paulista de Medicina Federal University of So Paulo (UNIFESP) So Paulo SP

Aphasic syndromes usually result from injuries to the dominant hemisphere of the brain. Despite the fact that localization of language functions shows little interindividual variability, several brain areas are simultaneously activated when language tasks are undertaken. Mechanisms of language recovery after brain injury to the dominant hemisphere seem to be relatively stereotyped, including activations of perilesional areas in the acute phase and of homologues of language areas in the non-dominant hemisphere in the subacute phase, later returning to dominant hemisphere activation in the chronic phase. Plasticity mechanisms reopen the critical period of language development, more specifically in what leads to disinhibition of the non-dominant hemisphere when brain lesions affect the dominant hemisphere. The non-dominant hemisphere plays an important role during recovery from aphasia, but currently available rehabilitation therapies have shown limited results for efficient language improvement. Large-scale randomized controlled trials that evaluate well-defined interventions in patients with aphasia are needed for stimulation of neuroplasticity mechanisms that enhance the role of the non-dominant hemisphere for language recovery. Ineffective treatment approaches should be replaced by more promising ones and the latter should be evaluated for proper application. The data generated by such studies could substantiate evidence-based rehabilitation strategies for patients with aphasia.

关键词： neural regeneration reviews linguistics aphasia language speech non-dominant hemisphere disability evaluation prognosis cerebrum function grants-supported paper neuroregeneration

Evidence-based Practice of Chinese Medicine in Physical Rehabilitation Science

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Chinese Journal of Integrative Medicine 2013年第10期19卷 723-729页

作者： Arthur de Sá ferreira Laboratory of Computational Simulation and Modeling in Rehabilitation Program of Rehabilitation ScienceCentro Universitario Augusto MottaRio de JaneiroRJBrazil(21041-021) Department of Physical Therapy UniversidadeSalgado de OliveiraNiteróiRJBrazil(21041-021)

Chinese medicine is among other traditional medical systems practiced either as a coadjutant intervention to Greek medicine or as the unique therapeutic intervention for illness prevention, treatment or rehabilitation. The complete spectrum from that traditional system includes acupuncture and moxibustion, herbal and food therapy, massage therapy （tuina）, physical exercises （taijiquan）, and breathing exercises （qigong）. In this article, it is presented several randomized controlled trials and systematic reviews on the application of all therapeutic modalities from Chinese medicine in the physical rehabilitation scenario. The discussed studies encompasses both ＂positive＂ and ＂negative＂ results of Chinese medicine intervention for disabilities due to illnesses of the nervous, musculoskeletal or cardiovascular systems. Additionally, the importance of the personalized approach for Chinese medicineand rehabilitation is emphasized together with the need for reproducible methods for pattern differentiation and intervention selection. Chinese medicine resources are recognized as promising methods for therapeutic rehabilitation and can be incorporated into the rehabilitation science. The wide variety of therapeutic resources explains why Chinese medicine is currently a multidisciplinary practice for health protection and promotion, early diagnosis and treatment as well as rehabilitation with roles in the public health care system.

关键词： rehabilitation physical therapy Chinese medicine

Unsupervised learning of load signatures to estimate energy-related building features using surrogate modelling techniques

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Building Simulation 2023年第7期16卷 1273-1286页

作者： Shane ferreira Burak Gunay Araz Ashouri Scott Shillinglaw Carleton University OttawaK1S 5B6Canada National Research Council Canada OttawaK1A 0R6Canada

Characterization of an existing building’s energy-related features is critical to inform maintenance and retrofit ***,existing field-scale characterization methods tend to be labour intensive,invasive,and require high fidelity longitudinal data gathered through tightly regulated *** highlights the need for a low cost,scalable,and efficient screening *** paper puts forward a surrogate model-based approach to rapidly estimate energy-related building *** this end,EnergyPlus models for 12 midrise office archetypes,all with a rectangular footprint,are *** thousand variants of each archetype are generated by altering envelope,causal heat gain,and heating,ventilation,and air conditioning operation features.A unique load signature is derived for each variant’s heating and cooling energy *** parameters of the load signatures are clustered,then each cluster is associated with a set of plausible energy-related *** accuracy of the results was evaluated using five test buildings not seen by the *** method could effectively identify building features with reasonable accuracy and no significant degradation in performance across all 12 archetypes.

关键词： remote characterization energy-related building features surrogate modelling cluster analysis

Conflictive management of small mammals considered as pests： A long way to evidence-based policy making

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Current Zoology 2012年第2期58卷 353-357页

作者： Catarina ferreira Miguel DELIBES-MATEOS Instituto de Investigacion en Recursos Cinegeicos IREC （CSIC-UCLM-JCCM） Ronda de Toledo s/n E-13071 Ciudad Real SPAIN CIBIO Centro de Investigacao em Biodiversidade e Recursos Geneticos Campus Agrario de Vairao 4485-661 Vairao PORTUGAL

This paper discusses the controversial management decisions made by policy-makers worldwide regarding poisoning campaigns aimed to control small mammal populations, often considered harmful economic pests. Aside from considerations re- garding the biological consequences of these campaigns, we argue that when society rejects all values of science and expertise then only badly supported and negligent decisions will be made about conservation and management issues. The extermination of small mammal species, some of which play crucial ecological roles in several regions of the world, is just an example of such discredit and misinformation. Without a strong commitment towards evidence-based policy-making, economic investments in re- search and development could be entirely compromised

关键词： Evidence-based policy Pest management Poisoning campaigns Small mammals