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小学生时代（大嘴英语） 2024年第7期 66-67页

作者： Maggie Murphy gina Lorena Maldonado(图) 不详

RSPSSL:A novel high-fidelity Raman spectral preprocessing scheme to enhance biomedical applications and chemical resolution visualization

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Light(Science & Applications) 2024年第2期13卷 366-386页

作者： Jiaqi Hu gina Jinna chen chenlong Xue Pei Liang Yanqun Xiang chuanlun Zhang Xiaokeng chi Guoying Liu Yanfang Ye Dongyu cui De Zhang Xiaojun yu Hong Dang Wen Zhang Junfan chen Quan Tang Penglai Guo Ho-Pui Ho Yuchao Li Longqing cong Perry Ping Shum State Key Laboratory of Optical Fiber and cable Manufacture Technology Guangdong Key Laboratory of Integrated Optoelectronics IntellisenseDepartment of EEESouthern University of Science and TechnologyShenzhen 518055China college of Optical and Electronic Technology China Jiliang UniversityHangzhou 310018China Department of Nasopharyngeal carcinoma Sun Yat-sen University Cancer CenterState Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineGuangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and TherapyGuangzhou 510060China Department of Ocean Science and Engineering Southern University of Science and TechnologyShenzhen 518055China Department of Nephrology Chaozhou People’s HospitalChaozhou 521011China clinical Research Design Division Sun Yatsen Memorial HospitalGuangzhouGuangdong 510120China School of Automation Northwestern Polytechnical UniversityXi’anShaanxi 710072China Department of Biomedical Engineering The Chinese University of Hong KongHong KongChina Guangdong Provincial Key Laboratory of Nanophotonic Manipulation Institute of NanophotonicsJinan UniversityGuangzhou 511443China

Raman spectroscopy has tremendous potential for material analysis with its molecular fingerprinting capability in many branches of science and *** is also an emerging omics technique for metabolic profiling to shape precision ***,precisely attributing vibration peaks coupled with specific environmental,instrumental,and specimen noise is *** Raman spectral preprocessing to remove statistical bias noise and sample-related errors should provide a powerful tool for valuable information ***,we propose a novel Raman spectral preprocessing scheme based on self-supervised learning(RSPSSL)with high capacity and spectral *** can preprocess arbitrary Raman spectra without further training at a speed of~1900 spectra per second without human *** experimental data preprocessing trial demonstrated its excellent capacity and signal fidelity with an 88%reduction in root mean square error and a 60%reduction in infinite norm(L__(∞))compared to established *** this advantage,it remarkably enhanced various biomedical applications with a 400%accuracy elevation(ΔAUc)in cancer diagnosis,an average 38%(few-shot)and 242%accuracy improvement in paraquat concentration prediction,and unsealed the chemical resolution of biomedical hyperspectral images,especially in the spectral fingerprint *** precisely preprocessed various Raman spectra from different spectroscopy devices,laboratories,and diverse *** scheme will enable biomedical mechanism screening with the label-free volumetric molecular imaging tool on organism and disease metabolomics profiling with a scenario of high throughput,cross-device,various analyte complexity,and diverse applications.

关键词： spectral scheme resolution

Obstetric Emergencies at the Kara University Hospital Maternity Ward: Sociodemographic, Etiological and Prognostic Aspects

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Open Journal of Obstetrics and Gynecology 2024年第1期14卷 69-76页

作者： Logbo-Akey Kossi Edem Bassowa Akila Ketevi Tina Kambote Yendoubé Patchidi Kibandou Amewouho Kofi Ajavon Dédé Régina Aboubakari Abdoul-Samadou Service de Gynécologie-Obstétrique CHU Kara Université de Kara Kara Togo Service de Gynécologie-Obstétrique CHU Campus Université de Lomé Lomé Togo Service de Gynécologie-Obstétrique CHU Sylvanus Olympio Université de Lomé Togo Faculté des sciences de la santé Université de Lomé Lomé Togo Service de Gynécologie-Obstétrique CHR Tomdé Université de Kara Togo

Introduction: Obstetric emergencies are common throughout the world and more particularly in developing countries where they are responsible for high maternal-fetal mortality and morbidity. Objective: Study obstetric emergencies in the maternity ward of Kara University Hospital. Method: Retrospective and descriptive study from April 1, 2022 to March 30, 2023, carried out in the Obstetrics and Gynecology Department of Kara University Hospital. Results: Eight hundred and thirty-five (835) obstetric emergencies were recorded out of 2215 admissions, i.e. a frequency of 37.7%. The average age of the patients was 26.7 with a range of 14 and 45 years. They were primigravidas (36.7%) and nulliparous (38.7%), referred (84.7%) and came from rural areas (72%). Emergencies occurred in the 3rd trimester in 74.1% and in parturients (54.1%). Preeclampsia (27%), cessation of progression of labor due to feto-pelvic disproportion (12.4%), postpartum hemorrhage (7.5%) constituted the main obstetric emergencies. In 44.8%, the delivery was carried out vaginally. Magnesium sulfate was the most used drug, i.e. 30.1%;followed by antihypertensive medications in 28.1%. Blood transfusion was performed in 24.3%. The evolution was simple in 90.9%. The maternal fatality rate was 1.6%. The perinatal case fatality rate was 12.3%. conclusion: Obstetric emergencies are common, dominated by preeclampsia, stopping progress of labor and postpartum hemorrhages. They are responsible for high morbidity and mortality.

关键词： Obstetric Emergency Kara University Hospital

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Interactome Analysis of Microtubule-targeting Agents Reveals cytotoxicity Bases in Normal cells

商业评论 2024年第5期 154-163页

作者：吕文晶吉娜·科拉雷利·奥康纳尼尔·汤普森陈媛熙麻省理工学院数字经济研究中心百森学院麻省理工学院FutureTech研究项目

加速度传感器芯片是一项微小而激进的创新.如今它已广泛应用于各种数字设备中.这种速度和方向传感器能告诉手机它是处于竖屏还是横屏模式,在汽车发生碰撞时及时弹出安全气囊,在我们玩虚拟网球时跟踪我们的正手击球动作.

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Genomics, Proteomics & Bioinformatics 2017年第6期15卷 352-360页

作者： Andres Julian Gutierrez-Escobar gina mendez-c.llejas Grupo de Investigaciones Biomedicas y Genetica Aplicada-GIBGA Universidad de Ciencias Aplicadas y Ambientales U.D.C.A.Bogota 111166Colombia

cancer causes millions of deaths annually and microtubule-targeting agents （MTAs） are the most commonly-used anti-cancer drugs. However, the high toxicity of MTAs on normal cells raises great concern. Due to the non-selectivity of MTA targets, we analyzed the interaction net- work in a non-cancerous human cell. Subnetworks of fourteen MTAs were reconstructed and the merged network was compared against a randomized network to evaluate the functional rich- ness. We found that 71.4% of the MTA interactome nodes are shared, which affects cellular pro- cesses such as apoptosis, cell differentiation, cell cycle control, stress response, and regulation of energy metabolism. Additionally, possible secondary targets were identified as client proteins of interphase microtubules. MTAs affect apoptosis signaling pathways by interacting with client pro- teins of interphase microtubules, suggesting that their primary targets are non-tumor cells. The paclitaxel and doxorubicin networks share essential topological axes, suggesting synergistic effects. This may explain the exacerbated toxicity observed when paclitaxel and doxorubicin are used in combination for cancer treatment.

关键词： cancer treatment Microtubule-targeting agentInteractome analysis cancer biology Apoptosis

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飓风改变舆论风向

环球科学 2024年第5期 16-17页

作者：吉娜·希门尼斯赵欢(译) 不详

去年夏天,野火烟雾笼罩了美国东海岸,突如其来的一场飓风摧毁了墨西哥的一个城镇,美国亚利桑那州菲尼克斯城数十人死于中暑,这些都让人们无法忽视气候变化的威力。最近,一项发表于《公共科学图书馆·气候》(PLOS climate)的新研究证实,... 详细信息

去年夏天,野火烟雾笼罩了美国东海岸,突如其来的一场飓风摧毁了墨西哥的一个城镇,美国亚利桑那州菲尼克斯城数十人死于中暑,这些都让人们无法忽视气候变化的威力。最近,一项发表于《公共科学图书馆·气候》(PLOS climate)的新研究证实,极端事件会影响公众对气候的讨论:每当飓风来袭,社交媒体上关于气候变化的推文数量就会激增。

关键词：社交媒体美国东海岸菲尼克斯极端事件气候变化科学图书馆飓风

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企业家信息 2024年第9期 77-81页

作者：吕文晶吉娜·科拉雷利·奥康纳尼尔·汤普森陈媛熙(译) 麻省理工学院数字经济研究中心百森学院麻省理工学院不详

加速度传感器芯片是一项微小而激进的创新。如今它已广泛应用于各种数字设备中。这种速度和方向传感器能告诉手机它是处于竖屏还是横屏模式,在汽车发生碰撞时及时弹出安全气囊,在我们玩虚拟网球时跟踪我们的正手击球动作。此外,它还能... 详细信息

加速度传感器芯片是一项微小而激进的创新。如今它已广泛应用于各种数字设备中。这种速度和方向传感器能告诉手机它是处于竖屏还是横屏模式,在汽车发生碰撞时及时弹出安全气囊,在我们玩虚拟网球时跟踪我们的正手击球动作。此外,它还能在地震或火山爆发之前,感知到地面刚刚开始颤动的那一瞬间。

关键词：正手击球火山爆发数字设备安全气囊方向传感器突破式创新

Domestic Wastewater Treatment through the Application of corchuros olitorius L. as Bio-coagulant in cagayan de Oro city, Philippines

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Journal of Environmental & Earth Sciences 2023年第1期5卷 108-120页

作者： gina cLacang corazon V.Ligaray Department of Environmental Science and Technology College of Science and MathematicsUniversity of Science and Technology of Southern PhilippinesCagayan de Oro9000Philippines Department of chemical Engineering and Technology College of Engineering and TechnologyMindanao State University-Iligan Institute of TechnologyIligan9200Philippines

This research paper presented the potential of corchuros olitorius *** a natural coagulant in the removal of turbidity,total suspended solids,and biochemical oxygen demand from the domestic wastewater of the University of Science and Technology of Southern *** of the natural coagulant and synthetic coagulant was employed prior to the treatment *** jar test method was used in the optimization and lab analysis including the gravimetric method,dilution technique,and digital *** optimization results of corchuros olitorius *** the jar test method revealed better removal at a lower dosage of 50 mg/L and a higher settling time of 90 *** characterization using FTIR analysis also suggests a functional group that influences coagulation *** the optimum dose and optimum settling time,results with the different treatment designs showed the highest removal at pH 7 showed%BOD removal of 89.78%(A75c25);85.98%(A25c75);88.76%(A50c50).TSS removal measured values of 88.50%(A75c25),85.56%(A25c75),and 87.16%(A50c50),while turbidity removal of 83.47%(A75c25),80.27%(A25c75),and 80.27%(A50c50).Statistically,measured values differ between treatment *** is suggested to investigate removal efficiency in more varied pH conditions,different settling times,stirring speed,and other variables for future studies.

关键词： corchorus olitorius L. Jar test Optimization Removal efficiency Wastewater

The Benefits of Pulmonary Rehabilitation Program on Post-Tuberculosis Bronchiectasis

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International Journal of clinical Medicine 2022年第12期13卷 561-570页

作者： Lenora c. Fernandez gina B. cairme Division of Pulmonary Medicine Philippine General Hospital University of the Philippines Manila Philippines Dominic Medical center Bacoor Philippines

Pulmonary rehabilitation has emerged as a recommended standard of care for patients with chronic lung disease. As in chronic obstructive pulmonary disease (cOPD), persons with other forms of chronic respiratory disease commonly experience deconditioning and decreased quality of life. The aim of this prospective study is to determine the effect of a 4-week pulmonary rehabilitation program (PRP) on patients diagnosed with post-pulmonary tuberculosis bronchiectasis in the Philippines. The participants were above 18 years of age, diagnosed to have stable Post-Pulmonary tuberculosis bronchiectasis with chest computerized tomography (cT) scan or chest radiograph showing bronchiectatic changes, consented to attend the PRP sessions and be included in the study. The subjects underwent PRP for 4 weeks with a total of 8 sessions and determination of Forced expiratory volume at 1 second (FEV1), forced vital capacity (FVc), quality of life determination using the Saint George Respiratory Disease Questionnaire (SGRQ), and exercise endurance using the 6-minute walking test (6 MWT), before and after the PRP. A total of fourteen patients, six males and eight females, aged from 28 - 72 years old, completed the 4-week pulmonary rehabilitation program. There were four ex-smokers and ten non-smokers with concomitant asthma and cOPD in some patients. There was significant improvement in the 6-minute walk test and quality of life after 4 weeks of rehabilitation program among the subjects with p value for 6 MWT at p = 0.0001 and p = 0.008 for SGRQ. conclusion: Pulmonary rehabilitation program led to a significant improvement in exercise capacity and health related quality of life among patients with post-pulmonary tuberculosis bronchiectasis.

关键词： Pulmonary Rehabilitation Post-Tuberculosis Bronchiectasis Post-Tuberculous Lung Disease

Optimized stateful material implication logic for three- dimensional data manipulation

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Nano Research 2016年第12期9卷 3914-3923页

作者： gina c. Adam Brian D. Hoskins Mirko Prezioso Dmitri B. Strukov Electrical and computer Engineering Department University of California Santa Barbara Santa Barbara CA 93106 USA Materials Department University of California Santa Barbara Santa Barbara CA 93106 USA

The monolithic three-dimensional integration of memory and logic circuits could dramatically improve the performance and energy efficiency of computing systems. Some conventional and emerging memories are suitable for vertical integration, including highly scalable metal-oxide resistive switching devices （＂memristors＂）. However, the integration of logic circuits has proven to be much more challenging than expected. In this study, we demonstrated memory and logic functionality in a monolithic three-dimensional circuit by adapting the recently proposed memristor-based stateful material implication logic. By modifying the original circuit to increase its robustness to device imperfections, we experimentally showed, for the first time, a reliable multi-cycle multi-gate material implication logic operation and half-adder circuit within a three- dimensional stack of monolithically integrated memristors. Direct data manipulation in three dimensions enables extremely compact and high-throughput logic- in-memory computing and, remarkably, presents a viable solution for the Feynman Grand challenge of implementing an 8-bit adder at the nanoscale.

关键词： material implication logic memristor resistive random-accessmemory (ReRAM) three-dimensionalintegration