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Variations of OCT measurements corrected for the magnification effect according to axial length and refractive error in children

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journal of Innovative Optical Health Sciences 2018年第1期11卷 123-137页

作者： Inmaculada Bueno-gimeno Enrique España-Gregori Andres Gene-Sampedro juan Carlos Ondategui-Parra Carlos j.Zapata-rodriguez Department of Optics and Optometry and Vision Science University of Valencia Spain Department of Surgery University of Valencia University Hospital La FeSpain Faculty of Optics and Optometry University Vision Centre Polytechnic University of CataloniaSpain

Purpose:The aim of this paper was to examine the distribution of macular,retinal nerve fiber layer(rNFL)thickness and optic disc parameters of myopic and hyperopic eyes in comparison withemmetropic control eyes and to investigate their variation according to axial length(AL)andspherical equivalent(SE)in healthy ***:This study included 293 pairs of eyes of 293children(145 boys and 148 girks),ranging in age from 6 to 17 years,Subjects were dividedaccording to SE in control(emmetropia,99 children),myopia(100 children)and hyperopia(94children)groups and according to axial AL in 68 short(rom≥22.00 mmto 25.00 mm,189)and long eyes(>25.00 mm,36).Macular parameters,rNFL thickness and opticdisc morphology were assessed by the Cirrus^(TM) *** was measured using the ***'s formula was used for calculating the corrected AL-related ocular *** Mean age(±SD)was 10.84±3.05 years;mean(±SD)SE was+0.14±0.51 D(range from8.75 to+8.25 D)and mean AL(±SD)was 23.12±*** rNFL thickness,averagemacular thickness and macular volume decreased as AL and myopia *** correlationsbetween AL/SE and optic disc parameters were found after correcting for magnification ***:AL and refractive error affect measurements of macular and rNFL thickness inhealthy *** make a correct interpretation of ocT measurements,ocular magnificationeffect should be taken into account by clinicians or OCT manufacturers.

关键词： Axial length refractive error children OCT measurements magnification fect

Estimation of mean water vapour residence time during tropical cyclones using a Lagrangian approach

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Tropical Cyclone research and review 2022年第2期11卷 76-87页

作者： Albenis Perez-Alarcon Patricia Coll-Hidalgo jose C.Fernandez-Alvarez raquel Nieto Luis gimeno Centro de Investigacion Marina Universidade de VigoEnvironmental Physics Laboratory(EPhysLab)OurenseSpain Departamento de Meteorología Instituto Superior de Tecnologías y Ciencias AplicadasUniversidad de La HabanaLa HabanaCuba Departamento de Meteorología Empresa Cubana de Navegacion AereaLa HabanaCuba

Tropical cyclone(TC)-related rainfall mostly depends on the atmospheric moisture uptake from local and remote *** this study,the mean water vapour residence time(MWVrT)was computed for precipitation related to TCs in each basin and on a global scale by applying a Lagrangian moisture source diagnostic *** to our results,the highest MWVrT was found for the TCs over the South Indian Ocean and South Pacific Ocean basins(~3.08 days),followed by the Western North Pacific Ocean,Central and East North Pacific Ocean,North Indian Ocean,and North Atlantic Ocean basins(which exhibited values of 2.98,2.94,2.85,and 2.72 days,respectively).We also found a statistically significant(prease in MWVrT,at a rate of~2.4 h/decade in the North Indian Ocean and~1.0 h/decade in the remaining *** average,the MWVrT decreased during the 24 h before TCs made landfall,and the atmospheric parcels precipitated faster after evaporation when TCs moved over land than over the *** research should focus on the relationship between global warming and MWVrT of atmospheric parcels that precipitate over TC positions.

关键词： Tropical cyclones Water vapour residence time Lagrangian approach Tropical cyclones precipitation

Insights into the origin of precipitation moisture for tropical cyclones during rapid intensification process

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Tropical Cyclone research and review 2024年第2期13卷 72-87页

作者： Albenis Perez-Alarcon jose C.Fernandez-Alvarez ricardo M.Trigo raquel Nieto Luis gimeno Centro de Investigacion Mari~na Universidade de VigoEnvironmental Physics Laboratory(EPhysLab)Campus As Lagoas s/nOurenseSpain Departamento de Meteorología Instituto Superior de Tecnologías y Ciencias AplicadasUniversidad de La HabanaLa HabanaCuba Instituto Dom Luiz(IDL) Facultade de Ci^enciasUniversidade de LisboaLisboaPortugal Departamento de Meteorologia Universidade Federal do Rio de JaneiroRio de JaneiroBrazil

In this study,we identiﬁed the moisture sources for the precipitation associated with tropical cyclones(TCs)during the rapid intensiﬁcation(rI)process from 1980 to 2018 by applying a Lagrangian moisture source diagnostic *** detected sixteen regions on a global scale for rI events distributed as follows:four in the North Atlantic(NATL),two in the Central and East Paciﬁc Ocean(NEPAC),the North Indian Ocean(NIO)and South Indian Ocean(SIO),and three in the South Paciﬁc Ocean(SPO)and the Western North Paciﬁc Ocean(WNP).The moisture uptake(MU)mostly was from the regions where TCs underwent *** Western NATL,tropical NATL,Caribbean Sea,the Gulf of Mexico and the Central America and Mexico landmass supported~85.4%of the precipitating moisture in the NATL,while the latter source and the eastern North Paciﬁc Ocean provided the higher amount of moisture in NEPAC(~84.3%).The Arabian Sea,the Bay of Bengal and the Indian Peninsula were the maj.r.moisture sources in NIO,contributing approximately 81.3%.The eastern and western parts of the Indian Ocean supplied most of the atmospheric humidity in SIO(~83.8%).The combined contributions(~87.9%)from the western and central SPO and the Coral Sea were notably higher in ***,TCs in the WNP basin mostly received moisture from the western North Paciﬁc Ocean,the Philippine Sea and the China Sea,accounting for 80.1%.The remaining moisture support in each basin came from the summed contributions of the remote ***,rI TCs gained more moisture up to 2500 km from the cyclone centre than those slow intensiﬁcation(SI)and the total MU was approximately three times higher during rI than ***,the patterns of the MU differences respond to the typical pathways of moisture transport in each basin.

关键词： Tropical cyclones rapid intensiﬁcation Moisture sources Precipitation Lagrangian moisture tracking

Unusual Presentation of Endometrial Cancer: A Clinicopathological Study of One Case

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Open journal of Obstetrics and Gynecology 2015年第1期5卷 23-27页

作者： j. Munné F. Alameda A. Bergueiro G. Mancebo L. Garrigós T. Baró B. Lloveras j. gimeno r. Carreras S. Serrano Department of Pathology Hospital del Mar Barcelona Spain Universitat Autonoma de Barcelona Barcelona Spain Department of Obstetrics and Gynecology Hospital del Mar Barcelona Spain Department of Oncology Hospital del Mar Barcelona Spain

Endometrial carcinoma is the most frequent genital tract malignancy. The first symptom (guide-symptom) is usually metrorrhagia;however, in around 10% of cases it is not. In contrast, osseous metastases are infrequent in endometrial cancer. The bones of the pelvis and lower extremities are those most frequently involved in disseminated metastatic diseases. In these cases, endometrial cancer is usually high grade (Grade III). Case report: 56-year-old woman who presented right inguinal pain. The X-ray showed a lithic lesion in the right ischium. A histopathological study demonstrated a metastatic lesion, suspected to be endometrial cancer. The computer tomography scan revealed a uterine mass and a second lithic lesion in the right tibia. The patient received chemotherapy (carboplatin and paclitaxel), and the bone lesions were irradiated. The patient is still alive 18 months after the diagnosis. This case emphasizes the importance of considering an endometrial primary tumor when evaluating bone metastasis of unknown primary cancer.

关键词： Osseous Metastasis Endometrial Carcinoma Immunohistochemistry

The Physiopathological Crossroads of Aging

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journal of Biosciences and Medicines 2019年第6期7卷 102-128页

作者： j.Lasierra-Cirujeda P.Coronel M.j.aza pascual-salcedo M.gimeno M.M.Aza Pascual Salcedo A.Lasierra-Ibanez C.Lasala-Aza logrono(la rioja) spain tedec-meji farma saalcala de henaresmadridspain pharmacy service la rioja health departmentla riojaspain pharmacy service aragon health servicezaragozaspain sciences faculty grade biochemistryuniversity of navarranavarraspain pharmacy faculty university of valenciavalenciaspain

Stress, inflammation and Plasminogen activator inhibitor 1 (PAI-1) are key mechanisms throughout the development of aging, constituting a crossroad in the most frequent pathologies that accompany it. Among metabolic processes, obesity, metabolic syndrome and type 2 diabetes mellitus are included and Alzheimer’s disease among the neurodegenerative processes. Stress is a mechanism of defense of the organism against exogenous and endogenous actions called stressors. In the case of low intensity stimuli, the organism responds with actions aimed at a physiological adaptation (Homeostasis). On the other hand, when a high intensity (experimental level) or chronic stimulus (oxidative stress) is repeated, structural and functional changes are observed in different organs with activation of the hypothalamus-pituitary-adrenal axis, the renin angiotensin system and the sympathetic nervous system, stimulating the production of hormones that release cytokines with proin-flammatory/antiinflammatory properties that play an important role in the previously mentioned pathologies, as well as a marked increase in PAI-1, a gene regulated by stress and by cytokines, with manifest action at the origin of thromboembolic disease, so frequent in aging. The objective of this review is to highlight the importance of the binomial stress and PAI-1 in aging and in the pathologies that accompany it. Because PAI-1 is part of the pathology and complications in aging, some authors suggest the study of PAI-1 inhibitors to achieve its physiological levels, as part of the treatment of these diseases.

关键词： Aging. Oxidative Stress Plasminogen Activator Inhibitor 1 Transforming Growth Factor Beta 1 Glutathione Alzheimer’s Disease

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地中海不同林火强度影响下的水蚀趋势

中国水土保持 2002年第7期 29-29页

作者： V.Andreu j.L.rubio E.gimeno-Garcia r.Cerni Centro de Investigaciones sobre Desertificación-CIDE CSICUniversitat de ValnciaGeneralitatValencianaCamèdelaMarjals/nCentro de Investigaciones sobre Desertificación-CIDECSICUniversitat de ValnciaGeneralitatValencianaCamèdelaMarjals/nCentro de

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地中海不同林火强度影响下的水蚀趋势

中国水土保持 2002年第7期 33-33页

作者： V.Andreu,j.L.rubio,E.gimeno-Garcia,r.Cerni Centro de Investigaciones sobre Desertificación-CIDE CSIC Universitat de Valncia GeneralitatValencianaCamèdelaMarjal s/n Centro de Investigaciones sobre Desertificación-CIDE CSIC Universitat de Valncia GeneralitatValencianaCamèdelaMarjal s/n Centro de

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霉菌毒素对奶牛的不良影响

中国乳业 2010年第7期 34-37页

作者： Alberto gimeno 王琦任东东卫麦霞郭万库美国特殊营养品公司深圳市赛斯特农业发展有限公司

霉菌毒素是由一些产毒霉菌菌株产生的有毒次级代谢产物。具体来说,霉菌毒素是在特定的物理、化学及生物条件下产生于缩合反应的多酮化合物,这个过程由霉菌来完成,它发生在当脂肪酸生物合成过程中酮组不再减少时。这些脂肪酸是一种被霉... 详细信息

霉菌毒素是由一些产毒霉菌菌株产生的有毒次级代谢产物。具体来说,霉菌毒素是在特定的物理、化学及生物条件下产生于缩合反应的多酮化合物,这个过程由霉菌来完成,它发生在当脂肪酸生物合成过程中酮组不再减少时。这些脂肪酸是一种被霉菌用作能源的初级代谢物。霉菌毒素通常形成于霉菌生长的对数生长阶段后期或平稳增长阶段的初期。霉菌毒素引起人类和动物的疾病和紊乱,被称为霉菌毒素中毒症。

关键词：霉菌毒素奶牛次级代谢产物对数生长阶段缩合反应合成过程霉菌生长脂肪酸

Influence of the Type of Circulatory/Ventricular Assistance in the Primary Graft Failure and Heart Transplantation Mortality

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World journal of Cardiovascular Diseases 2019年第8期9卷 545-552页

作者： raquel López-Vilella Ignacio j.Sánchez-Lázaro María Paz Fuset Cabanes Azucena Paj.r.s Moncho Lucía Donate Bertolín ricardo gimeno Costa Ignacio Moreno Puigdollers Luis Martínez Dolz Iratxe Zarragoikoetxea jauregui Salvador Torregrosa Puerta Luis Almenar Bonet Heart Failure and Transplant Unit Hospital Universitario y Politécnico La FeValenciaSpain Intensive Care Department Hospital Universitario y Politécnico La FeValenciaSpain Anesthesiology Department Hospital Universitario y Politécnico La FeValenciaSpain Cardiovascular Surgery Department Hospital Universitario y Politécnico La FeValenciaSpain

OBjECTIVES: In recent years, the percentage of heart transplantation (HT) with short/medium-term assistance devices has increased. This study aims at analyzing primary graft failure and in-hospital mortality according to the type of care. MATErIAL AND METHODS: From january 2013 to December?2017 all patients undergoing urgent HT with circulatory/ventricular assistance?were retrospectively and consecutively recruited. Combined transplants, retransplantations and pediatric transplants were excluded. The sample was divided in 10 groups according to the type of shot/medium term assistance devices. rESULTS: A total of 53 patients were recruited, 79% men, average age 49 ± 13 years. 26 patients (51%) had mechanical ventilation at the time of the HT. Primary graft failure occurred in 20 patients (38.5%), whilst it was more frequent in patients assisted with ECMO (8 patients in group 1 (45%) and 7 in group 2 (54%), p 0.5). 14 deaths (27%) were registered, whereas a higher mortality was observed in the group assisted with ECMO (6 patients in group 1 (34%) and 4 in group 2 (31%), p 0.6). Mortality was 17% in the group of non-urgent Levitronix. CONCLUSIONS: Despite not showing statistical significance due to the low number of patients in some subgroups, hospital?mortality was high in HT patients with circulatory assistance. A trend towards a higher incidence of primary graft failure and mortality in patients assisted with ECMO was observed. The direct implantation of a centrifugal pump as a bridge to urgent transplantation could identify a subgroup with a better prognosis.

关键词： Urgent Heart Transplantation Short-Medium Term Circulatory/Ventricular Assistance Primary Graft Failure