Unusual Presentation of Endometrial Cancer: A Clinicopathological Study of One Case
Unusual Presentation of Endometrial Cancer: A Clinicopathological Study of One Case作者机构：Department of Pathology Hospital del Mar Barcelona Spain Universitat Autonoma de Barcelona Barcelona Spain Department of Obstetrics and Gynecology Hospital del Mar Barcelona Spain Department of Oncology Hospital del Mar Barcelona Spain
出 版 物：《Open Journal of Obstetrics and Gynecology》 (妇产科期刊（英文）)
年 卷 期：2015年第5卷第1期
页 面：23-27页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Osseous Metastasis Endometrial Carcinoma Immunohistochemistry
摘 要：Endometrial carcinoma is the most frequent genital tract malignancy. The first symptom (guide-symptom) is usually metrorrhagia;however, in around 10% of cases it is not. In contrast, osseous metastases are infrequent in endometrial cancer. The bones of the pelvis and lower extremities are those most frequently involved in disseminated metastatic diseases. In these cases, endometrial cancer is usually high grade (Grade III). Case report: 56-year-old woman who presented right inguinal pain. The X-ray showed a lithic lesion in the right ischium. A histopathological study demonstrated a metastatic lesion, suspected to be endometrial cancer. The computer tomography scan revealed a uterine mass and a second lithic lesion in the right tibia. The patient received chemotherapy (carboplatin and paclitaxel), and the bone lesions were irradiated. The patient is still alive 18 months after the diagnosis. This case emphasizes the importance of considering an endometrial primary tumor when evaluating bone metastasis of unknown primary cancer.
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