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Highly compliant planar Hall effect sensor with sub 200 nT sensitivity

npj Flexible Electronics 2019年第1期3卷 25-30页

作者： Pablo Nicolás Granell Guoliang Wang gilbert santiago cañon bermudez Tobias Kosub Federico Golmar Laura Steren Jürgen Fassbender Denys Makarov Helmholtz-Zentrum Dresden-Rossendorf e.V. Institute of Ion Beam Physics and Materials ResearchBautzner Landstrasse 40001328 DresdenGermany Instituto Nacional de Tecnología Industrial(INTI) Centro de Micro-y Nanoelectrónica del Bicentenario(CMNB)Av.Gral Paz 5445B1650KNA San MartínBuenos AiresArgentina Escuela de Ciencia y Tecnología UNSAMCampus MigueleteB1650KNA San MartínBuenos AiresArgentina Consejo Nacional de Investigaciones Científicas y Técnicas C1425FQB Ciudad Autónoma de Buenos AiresArgentina Instituto de Nanociencia y Nanotecnología B1650KNA San MartínBuenos AiresArgentina Dpto.Materia Condensada Centro Atómico ConstituyentesB1650 San MartínBuenos AiresArgentina

Being a facet of flexible electronics,mechanically reshapeable magnetic field sensorics enable novel device ideas for soft robotics,interactive devices for virtual-and augmented reality and point of care *** applications demand mechanically compliant yet robust sensor devices revealing high sensitivity to small magnetic *** push the detection limit of highly compliant and linear magnetic field sensors to be in the sub-µT range,we explore a new fundamental concept for magnetic field sensing,namely the planar Hall effect in magnetic thin *** their remarkable bendability down to 1 mm,these compliant planar Hall effect sensors allow for an efficient detection of magnetic fields as small as 200 nT with a limit of detection of 20 *** demonstrate the application potential of these devices as a direction(angle)as well as proximity(distance)sensors of tiny magnetic fields emanating from magnetically functionalized *** their intrinsic linearity and simplicity of fabrication,these compliant planar Hall effect sensors have the potential to become a standard solution for low field applications of shapeable magnetoelectronics in point of care applications and on-skin interactive electronics.

关键词： interactive planar limit

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Identification of Prophages within the Mycobacterium avium 104 Genome and the Link of Their Function Regarding to Environment Survival

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Advances in Microbiology 2016年第13期6卷 927-941页

作者： Miao Zhao Kerrigan gilbert Lia Danelishvili Brendan Jeffrey Luiz E. bermudez Program of Biology Oregon State University Corvallis OR USA Department of Biomedical Sciences College of Veterinary Medicine Oregon State University Corvallis OR USA Department of Microbiology Oregon State University Corvallis OR USA

Mycobacterium avium is an opportunistic bacterium associated with pathogenic behavior in both humans and animals. M. avium has evolved as a pathogen by having an environmental component in its life style. Prophages are the integrated viral forms in bacterium genome. They constitute about 10% - 20% of genome of many bacteria and they contribute to pathogenicity of microbes. We investigated whether the M. avium 104 genome contained prophages and evaluated the genes/proteins for putative functions. Three prophage genes were identified in the M. avium 104 database, and sequences were analyzed for specific motifs. The prophage sequences were then cloned in Mycobacterium smegmatis and the bacterial phenotype was evaluated in gain of function assays for environmental stresses, such as tolerance to extreme temperatures, UV light, biofilm formation and resistance to acid as well as macrophage survival. The results indicate that two of the prophage genes, MAV_0696 and MAV_2265, confer M. smegmatis with enhanced ability to produce biofilm. Using a Real-Time PCR, it was determined that MAV_0696 and MAV_2265 transcripts were upregulated upon biofilm formation by M. avium. The expression of MAV_2265 gene was significantly higher at all selected time points. In addition, the expression of MAV_2265 in M. smegmatis also led to significantly greater survival rate at pH 5.0 compared to the wild-type control. None of the other physical abilities were altered by overexpressing the prophage genes in M. smegmatis. In summary, we identified three prophage sequences in M. avium 104, from which two of them were found to be associated with biofilm formation and one with resistance to the acidic environment. Future studies will identify the mechanisms involved in the prophages function.

关键词： Mycobacterum avium Prophage Virulence Environment

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Trends in Corporate Social Responsibility Among Public Service Media in Europe

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Economics World 2017年第6期5卷 560-565页

作者： Tania Femandez-Lombao Andrea Valencia-bermudez Francisco campos-Freire University of santiago de Compostela Santiago Spain

Corporate Social Responsibility （CSR） is the voluntary commitment taken over by companies in social, economic, and environmental terms. The aim is to counteract impacts generated by their activity. While the concept is genuinely linked to the private sector, this self-regulated system has been steadily introduced in some European public service media. Indeed, CSR is one of the mechanisms to face the challenges of the sector, both the financial crisis and the lack of trust. Seven public service media from the European Union are reporting--via their websites--on their CSR strategies. Annual reports on their performance are issued by the German ZDF, the Spanish RTVE, the Portuguese RTP, the British BBC, the Irish RTI~, the Finnish YLE, and the Italian RAI. Also, four other corporations--VRT and RTBF from Belgium, FT from France, and DR from Denmark include a section on corporate social responsibility on their annual reports. The aim of this paper is to know which of the trends in CSR are dominant among public service media in Europe, namely economy, environment, and society. The content analysis of corporate reports is the method used for the research.

关键词： corporate social responsibility public service media accountability European Union

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Labat法坐骨神经阻滞下局部麻醉药低容量高浓度较高容量低浓度更有效：一项前瞻性随机对照研究

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麻醉与镇痛 2010年第2期6卷 83-86页

作者： Manuel Taboada Muniz, MD, PhD Jaime Rodriguez, MD, PhD Maria bermudez, MD Cristina Valino, MD Noemi Blanco, MD Marcos Amor, MD Pilar, Aguirre, MD Ana Masid, MD Joaquin Cortes, MD, Ph Julian Alvarez, MD, PhD Peter G. Atanassoff, MD 杨光(译) 崔苏扬(校) Department of Anesthesiology University of Santiago de Compostela Hospital Clfnico Universitario de Santiago Spain Department of Anesthesiology Hospital Meixoeiro CHUVI Vigo Spain Department of Anesthesiology Yale University School of Medicine New Haven Connecticut 不详

背景有很多因素可以明显影响外周神经阻滞的起效时间和成功率，本项前瞻、随机、双盲研究比较了Labat后路法行坐骨神经阻滞时，单剂量的甲哌卡因300mg分别稀释至20和30ml注射后的阻滞效果差异。方法90例行足部手术的患者，随机分为2组... 详细信息

背景有很多因素可以明显影响外周神经阻滞的起效时间和成功率，本项前瞻、随机、双盲研究比较了Labat后路法行坐骨神经阻滞时，单剂量的甲哌卡因300mg分别稀释至20和30ml注射后的阻滞效果差异。方法90例行足部手术的患者，随机分为2组接受坐骨神经阻滞，一组给予1．5％甲哌卡因20m1（45例），另一组给予1％甲哌卡因30m1（45例），所有阻滞均在神经刺激仪定位下进行（参数为刺激频率2Hz；刺激电流为1．5～0．5mA）。两组中，神经刺激反应在〈0．5mA时引出，亦可以定向诱发足部肌肉向跖侧屈曲，分别记录胫神经和腓总神经的运动感觉功能被阻滞的起效时间。而坐骨神经支配区域的针刺感觉消失，同时足部跖曲及背曲运动消失为阻滞成功的标准。结果用20ml的1．5％甲哌卡因组阻滞成功率（96．6％）显著高于30ml的1％甲哌卡因组（68．9％，P〈0．05）。而前者达到感觉与运动完全阻滞所需要的时间（11±6分钟，13±7分钟）也短于后者（17±8分钟，19±8分钟，P〈0．05）。结论Labat法行坐骨神经阻滞时，与高容量低浓度的局部麻醉药（1％甲哌卡因）比较，使用低容量高浓度的局部麻醉药（1．5％甲哌卡因）能够获得更高的阻滞成功率及更短的起效时间。

关键词：前瞻性随机对照研究坐骨神经阻滞局部麻醉药低浓度高容量低容量运动感觉功能甲哌卡因

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