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Predicting the outcome of closed-loop small bowel obstruction by preoperative characteristics

World journal of Gastrointestinal Surgery 2022年第6期14卷 556-566页

作者： Masja K Toneman Bente M de Kok Frank M Zijta Stanley Oei gijs j d van acker Marinke Westerterp Anne E M van der Pool department of Surgery Haaglanden Medical CentreThe Hague 2512 VANetherlands department of Radiology Haaglanden Medical CentreThe Hague 2512 VANetherlands

BACKGROUNd Closed-loop small bowel obstruction(CL-SBO)can threaten the viability of the intestine by obstructing a bowel segment at two adjacent *** recognition and surgery are *** To analyze the outcomes of patients who underwent surgery for CL-SBO and to evaluate clinical *** Patients who underwent surgery for suspected CL-BSO on computed tomography(CT)at a single center between 2013 and 2019 were evaluated *** were divided into three groups by perioperative outcome,including viable bowel,reversible ischemia,and irreversible *** and laboratorial variables at presentation were compared and postoperative outcomes were *** Of 148 patients with CL-SBO,28(19%)had a perioperative viable small bowel,86(58%)had reversible ischemia,and 34(23%)had irreversible *** with a higher age had higher risk for perioperative irreversible ischemia[odds ratio(OR):1.03,95%confidence interval(CI):0.99-1.06].Patients with American Society of Anaesthesiologists(ASA)classification≥3 had higher risk of perioperative irreversible ischemia compared to lower ASA classifications(OR:3.76,95%CI:1.31-10.81).Eighty-six patients(58%)did not have elevated C-reactive protein(>10 mg/L),and between-group differences were *** in-hospital stay was significantly longer for patients with irreversible ischemia(median 8 d,P=0.001)than for those with reversible ischemia(median 6 d)or a viable bowel(median 5 d).Postoperative morbidity was significantly higher in patients with perioperative irreversible ischemia(45%,P=0.043)compared with reversible ischemia(20%)and viable bowel(4%).CONCLUSION Older patients or those with higher ASA classification had an increased risk of irreversible ischemia in case of *** irreversible ischemia,postoperative morbidity was increased.

关键词： General surgery Laparoscopy Laparotomy Critical care Intestinal obstruction Morbidity

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Increasing the dry Matter And Energy Yield Potential of Poplar Biomass in Flanders

Increasing the Dry Matter And Energy Yield Potential of Popl...

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The 18th European Biomass Conference and Exhibition

作者： vansteenkiste d. Prins W. van acker j.

Merely 2% of the gross energy consumption in Flanders（Belgium） is covered by biomass. Key questions to be addressed are（1） how the future regional biomass supply for renewable energy production will be ensured, and（2） how this feedstock can be converted most intelligently into energy. We propose selecting and deploying highly productive poplars-in terms of both yield and quality-in short-rotation cultures（SRC） on marginal arable land. These poplars should provide readily accessible biomass that is adapted to thermochemical conversion technologies and for combined heat and power generation. Based on a theoretical scenario analysis with different yield options, it was estimated that pyrolytic intermediate products from poplar may allow significant displacements of various sources and sinks of primary energy. To evaluate the feasibility of the more ambitious scenarios, we envisage advanced comparative structural research of poplar cultivars and detailed study of the decomposition behavior of poplars in thermochemical experiments. Feedstock and intermediary product characterization will be carried out at various scale levels（submicron to cm, in 2d and 3d） and processing stages by using a top-notch computer-tomographic scanning installation（UGCT Nanoscan） and advanced dynamic and static thermal analysis equipment（dSC-TGA）. Some preliminary results are presented.

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diagnostic value of drain amylase for detecting intrathoracic leakage after esophagectomy

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World journal of Gastroenterology 2015年第30期21卷 9118-9125页

作者： gijs HK Berkelmans Ewout A Kouwenhoven Boudewijn jj Smeets Teus j Weijs Luis C Silva Corten Marc j van det Grard AP Nieuwenhuijzen Misha dP Luyer department of Surgery Catharina Hospital department of Surgery ZGT Hospital group Twente

AIM:To investigate the value of elevated drain amylase concentrations for detecting anastomotic leakage(AL) after minimally invasive Ivor-Lewis esophagectomy(MIILE).METHOdS:This was a retrospective analysis of prospectively collected data in two hospitals in the Netherlands. Consecutive patients undergoing MI-ILE were included. A jackson-Pratt drain next to the dorsal side of the anastomosis and bilateral chest drains were placed at the end of the thoracoscopic procedure. Amylase levels in drain fluid were determined in all patients during at least the first four postoperative days. Contrast computed tomography scans and/or endoscopic imaging were performed in cases of a clinically suspected AL. Anastomotic leakage was defined as any sign of leakage of the esophago-gastric anastomosis on endoscopy,re-operation,radiographic investigations,post mortal examination or when gastro-intestinal contents were found in drain fluid. Receiver operator characteristic curves were used to determine the cut-off values. Sensitivity,specificity,positive predictive value,negative predictive value,risk ratio and overall test accuracy were calculated for elevated drain amylase ***:A t o t a l o f 8 9 p a t ie n t s w e re in c lu d e d between March 2013 and August 2014. No differences in group characteristics were observed between patients with and without AL,except for age. Patients with AL were older than were patients without AL(P = 0.01). One patient(1.1%) without AL died within 30 d after surgery due to pneumonia and acute respiratory distress syndrome. Anastomotic leakage that required any intervention occurred in 15 patients(16.9%). Patients with proven anastomotic leakage had higher drain amylase levels than patients without anastomotic leakage [median 384 IU/L(IQR 34-6263) vs median 37 IU/L(IQR 26-66),P = 0.003]. Optimal cut-off values on postoperative days 1,2,and 3 were 350 IU/L,200 IU/L and 160 IU/L,respectively. An elevated amylase level was found in 9 o

关键词： Esophageal cancer Esophageal surgery Anastomotic leakage Amylase drain fluid

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3d对称采样的理论和实践

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石油物探译丛 1999年第3期 47-52页

作者： gijs j.O.Vermeer 吴龙丽胜利石油管理局地球物理勘探开发公司研究所山东东营257100

简单地说,3d对称采样的标准是:1)炮点间隔位置=接收点间隔位置;2)炮线间隔=接收线间隔;3)最大纵测线炮检距=最大横测线炮检距;4)炮点和接收点的中心排列数据采集;5)所需的炮点组合和检波器组合相等。把这些标准应用于正交观测系统中可... 详细信息

简单地说,3d对称采样的标准是:1)炮点间隔位置=接收点间隔位置;2)炮线间隔=接收线间隔;3)最大纵测线炮检距=最大横测线炮检距;4)炮点和接收点的中心排列数据采集;5)所需的炮点组合和检波器组合相等。把这些标准应用于正交观测系统中可得到(a)正方形形状的十字排列;(b)共接收点道集与共炮点道集相似;(c)横测线方向的地震特征与纵测线方向上的相同。

关键词： 3d对称采样地震勘探炮检距采样

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3-d对称采样

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国外油气勘探 1999年第4期11卷 455-478页

作者： gijs j.O.Vermeer 郎克让朱衍镛物探局地调二处对外合作部

3-d地震勘探技术作为获得详细地下资料的方法,在工业上已得到了认可。但3-d地震数据采集的成本现在是将来也永远是相当高的。因此选择正确的观测系统显得特别重要。直到目前,还没有一套完整的理论能够告诉我们是什么构成一个优秀的3-d... 详细信息

3-d地震勘探技术作为获得详细地下资料的方法,在工业上已得到了认可。但3-d地震数据采集的成本现在是将来也永远是相当高的。因此选择正确的观测系统显得特别重要。直到目前,还没有一套完整的理论能够告诉我们是什么构成一个优秀的3-d观测系统,这样一个系统如何去设计。本文提出的3-d对称采样理论的目的是填补这项空白,可以作为3-d观测系统设计和分析的坚实基础。从80代起,有关设计2-d勘探的理论和方法就开始发展起来。Anstey提出了叠加组合的方法,Ongkiehong和Askin提出了自动采集技术,Vermeer提出了对称采样技术。在本文中,2-d观测系统的对称采样理论扩展到目前正在使用的最重要的3-d观测系统中。在3-d对称采样中,观测系统的空间特征是基本要素,空间特征重要是因为大部分地震处理程序是在把相邻道合并到新输出道上的某个空间域进行的,而且解释人员必须把3-d地震数据体的空间特征成图。一段时间以来,曾出现了各式各样的测量观测系统来进行3-d地震数据采集。所有这些观测系统都是与5-d叠前波场(4个空间坐标轴描述了震源和检波点的位置,第5个坐标轴表示了旅行时)的全采样有关的折衷方法。因此得出,大多数观测系统可以被认为是5-d波场的3-d子集的集合,每一个子集仅有两个变化的空间坐标。每个子集的地震道的空间分布变化是缓慢而有规律的。该性质使3-d勘探具有空间连续性,如果子集的采样合适,并可延伸到最大范围时,就可以充分利用空间连续性。 2-d对称采样标准——等炮距和接收距及等炮检组合同样也用于3-d对称采样,但对不同的观测系统要附加不同的标准。正交观测系统(平行炮线与平行接收线正交的观测系统)的附加标准就是为了保证最大横测线炮检距等于最大纵测线炮检距。 3-d对称采样观测系统简化了3-d观测系统的设计。一张简单的地球物理要求清单(空间连续性、分辨率、浅目的层和深目的层的可绘图性、信噪比)限制了勘探参数的选取。在以上所考虑的因素中,也已隐含地照顾到了炮检距和方位角分布。在野外具体实施时,要求认真计划以防失去空间连续性。

关键词：三维对称采样观测系统 3-d 地震勘探

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Microfluidics-enabled phenotyping of a whole population of *** worms over their embryonic and post-embryonic development at single-organism resolution

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Microsystems & Nanoengineering 2018年第1期4卷 345-355页

作者： Maria Cristina Letizia Matteo Cornaglia Raphaël Trouillon Vincenzo Sorrentino Laurent Mouchiroud Maroun S.Bou Sleiman johan Auwerx Martin A.M.gijs Ecole Polytechnique Fédérale de Lausanne Laboratory of MicrosystemsLausanneSwitzerland Ecole Polytechnique Fédérale de Lausanne Laboratory of Integrative Systems PhysiologyLausanneSwitzerland

The organism Caenorhabditis elegans is a performant model system for studying human biological processes and diseases,but until now all phenome data are produced as population-averaged *** of individual responses to drug treatments would however be more ***,a new strategy to track different phenotypic traits of individual *** nematodes throughout their full life-cycle-i.e.,embryonic and post-embryonic development,until adulthood onset,differently from life-span-is *** an automated fashion,single worms were synchronized,isolated,and cultured from egg to adulthood in a microfluidic device,where their identity was preserved during their whole *** phenotypes were monitored and quantified for each animal,resulting in high-content phenome ***,the method was validated by analyzing the response of *** to doxycycline,an antibiotic fairly well-known to prolong the development and activate mitochondrial stress-response pathways in different ***,the obtained extensive single-worm phenome not only confirmed the dramatic doxycycline effect on the worm developmental delay,but more importantly revealed subtle yet severe treatment-dependent phenotypes that are representative of minority subgroups and would have otherwise stayed hidden in an averaged *** heterogeneous response started during the embryonic development,which makes essential having a dedicated chip that allows including this early developmental stage in the drug *** approach would therefore allow elucidating pharmaceutical or therapeutic responses that so far were still being overlooked.

关键词： fluid treatment otherwise

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建立卒中医疗体系的建议美国卒中协会特别工作组关于建立卒中体系的建议

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国际脑血管病杂志 2005年第12期13卷 883-894页

作者： Lee H. Schwamm Arthur Pancioli joe E. acker Ⅲ Larry B. Goldstein Richard d. Zorowitz Timothy j. Shephard Peter Moyer Mark Gorman S. Claiborne johnston Pamela W. duncan Phil Gorelick jeffery Frank Steven K. Stranne Renee Smith William Federspiel Katie B. Horton Ellen Magnis Robert j. Adams 林豪杰董继宏金丽蓉彭伟锋汪昕复旦大学附属中山医院神经内科

在美国,卒中一直是残疾和死亡的重要原因.每年约有70万例美国人新发或复发卒中,在与其他心血管病分开评价时,卒中在美国仍是第三位死亡原因.在美国卒中还是严重和长期残疾的第一位原因[1].

关键词：初级卒中中心二级预防患者医务人员医务工作者急性卒中防治体系医疗体系美国卒中协会医疗亚急性期工作组

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