检索结果-南通市图书馆

A Double Assessment of Privacy Risks Aboard Top‑Selling Cars

在线全文

学校读者我要写书评

暂无评论

Automotive Innovation 2023年第2期6卷 146-163页

作者： giampaolo Bella Pietro Biondi Giuseppe Tudisco Dipartimento di Matematica e Informatica Universitàdegli Studi di CataniaCataniaItaly Osservatorio Astrofisico di Catania Istituto Nazionale di AstrofisicaCataniaItaly

The advanced and personalised experience that modern cars offer makes them more and more *** example,the cabin preferences of the possible drivers must be recorded and associated to some identity,while such data could be exploited to deduce sensitive information about the driver’s ***,drivers’privacy must be taken seriously,requiring a dedicated risk assessment framework,as presented in this paper through a double assessment combining the asset-oriented ISO approach with the threat-oriented STRIDE *** framework is tailored to the level of specific car brand and demonstrated on the ten top-selling brands as well as,due to its innovative character,*** two approaches yield different,but complementary findings,demonstrating the additional insights gained through their parallel adoption.

关键词： Automotive Cyber physical systems Risk management ISO 27005 STRIDE

Morbidity and psychological impact of prostate biopsy： the future calls for a change

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2014年第3期16卷 415-417页

作者： Andrea Minervini Gianni Vittori giampaolo Siena Marco Carini Department of Urology University of FlorenceCareggi Hospital Florence Italy.

Currently transrectal ultrasound-guided prostate biopsy （TRUS-Bx） is one of the most common urological procedures, with more than 1 million performed per year in Europe and the United States. Among patients undergoing TRUS-Bx, approximately one-third will receive a diagnosis of prostate cancer （PCa）, while two-thirds receive a negative result on initial biopsy. Negative biopsy patients maintain an estimated risk of repeated biopsy of 12% at I year and 38% at 5 years. 2 Standard TRUS-Bx is likely to systematically miss significant tumors, particularly in the anterior and apical parts of the gland.3 A crucial aim of urologists in the next decade is to increase the accuracy of the procedure and avoid the use of inappropriate biopsies.

关键词： Morbidity psychological impact prostate biopsy

Embedded fuzzing:a review of challenges,tools,and solutions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cybersecurity 2022年第4期5卷 1-18页

作者： Max Eisele Marcello Maugeri Rachna Shriwas Christopher Huth giampaolo Bella Safety Security and PrivacyRobert Bosch GmbHRenningenGermany Dept.of Math and Computer Science Universita degli Studi di CataniaCataniaItaly RBEl Robert Bosch GmbHBangaloreIndia.

Fuzzing has become one of the best-established methods to uncover software ***,the market of embedded systems,which binds the software execution tightly to the very hardware architecture,has grown at a steady pace,and that pace is anticipated to become yet more sustained in the near *** systems also beneft from fuzzing,but the innumerable existing architectures and hardware peripherals complicate the development of general and usable approaches,hence a plethora of tools have recently *** comes a stringent need for a systematic review in the area of fuzzing approaches for embedded systems,which we term'embedded fuzzing"for *** inclusion criteria chosen in this article are semi-objective in their coverage of the most relevant publication venues as well as of our personal *** review rests on a formal definition we develop to represent the realm of embedded *** continues by discussing the approaches that satisfy the inclusion criteria,then defines the relevant elements of comparison and groups the approaches according to how the execution environment is served to the system under *** resulting review produces a table with 42 entries,which in turn supports discussion suggesting vast room for future research due to the limitations noted.

关键词： Embedded systems Dynamic analysis Vulnerability mining Embedded security Software security

Personalized surgical management of colorectal cancer in elderly population

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2014年第14期20卷 3762-3777页

作者： giampaolo Ugolini Federico Ghignone Davide Zattoni Giacomo Veronese Isacco Montroni Department of Medical and Surgical Sciences University of BolognaPoliclinico S. OrsolaMalpighi

Colorectal cancer(CRC)in the elderly is extremely common but only a few clinicians are familiar with the complexity of issues which present in the geriatric *** this phase of the life cycle,treatment is frequently *** the fact that,nowadays,older people tend to be healthier than in previous generations,surgical undertreatment is frequently *** the other hand,surgical overtreatment in the vulnerable or frail patient can lead to unacceptable postoperative outcomes with high mortality or persistent ***,due to the geriatric patient being traditionally excluded from randomized controlled trials for a variety of factors(heterogeneity,frailty,etc.),there is a dearth of evidence-based clinical guidelines for the management of these *** objective of this review was to summarize the most relevant clinical studies available in order to assist clinicians in the management of CRC in the *** than in any other patient group,both surgical and non-surgical management strategies should be carefully individualized in the elderly population affected by *** cure and sphincter preservation are the primary goals,many other variables need to be taken into account,such as maintenance of cognitive status,independence,life expectancy and quality of life.

关键词： Elderly Colorectal cancer Surgery Personalized treatment Geriatric assessment

B cell development is critically dependent on NFATc1 activity

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2019年第5期16卷 508-520页

作者： Sabrina giampaolo Gabriela Wojcik Stefan Klein-Hessling Edgar Serfling Amiya K.Patra Department of Molecular Pathology Institute of PathologyUniversity of WürzburgJosef Schneider-Str.297080 WürzburgGermany Institute of Translational and Stratified Medicine Faculty of Medicine and DentistryUniversity of PlymouthPlymouth PL68BUUK Comprehensive Cancer Center Mainfranken University of WürzburgJosef Schneider-Str.697080 WürzburgGermany

B cell development in bone marrow is a precisely regulated complex *** successive stages of differentiation,which are regulated by a multitude of signaling pathways and an array of lineage-specific transcription factors,the common lymphoid progenitors ultimately give rise to mature B *** to early thymocyte development in the thymus,early B cell development in bone marrow is critically dependent on IL-7 *** this IL-7-dependent stage of differentiation,several transcription factors,such as E2A,EBF1,and Pax5,among others,play indispensable roles in B lineage specification and *** recent studies have implicated several other transcription factors in B cell development,the role of NFATc1 in early B cell developmental stages is not ***,using multiple gene-manipulated mouse models and applying various experimental methods,we show that NFATc1 activity is vital for early B cell *** of NFATc1 activity in pro-B cells suppresses EBF1 expression,impairs immunoglobulin gene rearrangement,and thereby preBCR formation,resulting in defective B cell ***,deficiency in NFATc1 activity arrested the pro-B cell transition to the pre-B cell stage,leading to severe B cell *** findings suggest that,along with other transcription factors,NFATc1 is a critical component of the signaling mechanism that facilitates early B cell differentiation.

关键词： Differentiation EBF1 NFATc1 Pro-B Pre-B

The reuse of abandoned Acquaresi mine voids for storage of the Masua flotation tailings

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Coal Science & Technology 2014年第2期1卷 213-220页

作者： Pier Paolo Manca Paolo Desogus giampaolo Orru DICAAR Department of Civil EngineeringEnvironmental and ArchitectureUniversity of CagliariCagliariItaly

Often in abandoned mine sites are present both underground voids produced by mining and the tailings of treatment *** interesting solution for the rehabilitation of the sites would be to place the tailings of the process in the underground mining voids,thus obtaining the reclamation of surface areas and the stabilization of abandoned voids to prevent the dangerous phenomena of ***,these operations require inert waste,which must not be source of pollution,and the choice of a water/solid optimum to ensure good conditions of pumpability.

关键词： Acquaresi mine Mine voids Masua Flotation tailings

Exocrine pancreatic function assessed by secretin cholangio-Wirsung magnetic resonance imaging

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2008年第2期7卷 192-195页

作者： Lucia Calculli Raffaele Pezzilli Marta Fiscaletti Riccardo Casadei Carla Brindisi giampaolo Gavelli Departments of Radiology Digestive Diseases and Internal Medicineand General SurgerySant'Orsola-Malpighi Hospital Bologna Italy

BACKGROUND:Magnetic resonance cholangiopancreato-graphy (MRCP) is useful to assess exocrine pancreatic function by combining rapid imaging acquisition with the administration of secretin, a gastrointestinal hormone that stimulates the secretion of bile and pancreatic juice. However, extensive data on this method are lacking. This study aimed to determine whether MRCP with secretin administration is able to simultaneously detect alterations of both the pancreatic ducts and exocrine pancreatic function. METHODS:All subjects older than 18 years who underwent magnetic resonance imaging (MRI) and cholangio-Wirsung magnetic resonance imaging (CWMRI) for suspicion of benign or malignant pancreatic diseases from January 2006 to December 2006 were enrolled in the study. MRI and CWMRI were carried out using a dedicated apparatus. RESULTS:Eighty-seven patients (46 males, 41 females, mean age 59.7±14.6, range 27-87 years) were enrolled. Of the 87 patients, 39 had a normal pancreas on imaging, 20 had an intrapapillary mucinous tumor (IPMT), and the rest had chronic pancreatitis (7), serous cystadenoma (6), a previous attack of acute biliary pancreatitis (5), congenital ductal abnormalities (5), mucinous cystadenoma (3), previous pancreatic head resection for autoimmune pancreatitis (1), or cholangiocarcinoma (1). Morphologically, we found two pseudocysts (one of the 7 patients with chronic pancreatitis, and one of the 5 patients after an attack of acute pancreatitis;the latter pseudocyst communicated with the main pancreatic duct). Calcifications were found in 3 of the 7 patients with chronic pancreatitis. All patients with IPMT and mucinous cystadenoma and 3 patients with serous cystadenoma were histologically confirmed. The remaining patients were followed up adequately to confirm the diagnosis by imaging. According to the Matos criteria, 73 patients (83.9%) were of grade 3, 8 grade 2, 4 grade 1, and 2 grade 0. The only pancreatic diseases which impaired the exocrine pancreati

关键词： chronic pancreatitis magnetic resonance cholangiopancreatography pancreatic neoplasms pancreatic insufficiency

How to select elderly colorectal cancer patients for surgery: a pilot study in an Italian academic medical center

在线全文

学校读者我要写书评

暂无评论

Cancer Biology & Medicine 2015年第4期12卷 302-307页

作者： giampaolo Ugolini Francesco Pasini Federico Ghignone Davide Zattoni Maria Letizia Bacchi Reggiani Daniele Parlanti Isacco Montroni Department of Medical and Surgical Sciences University of Bologna S.Orsola Malpighi Hospital

Objective: Cancer is one of the most common diagnoses in elderly patients. Of all types of abdominal cancer, colorectal cancer(CRC) is undoubtedly the most frequent. Median age at diagnosis is approximately 70 years old worldwide. Due to the multiple comorbidities affecting elderly people, frailty evaluation is very important in order to avoid over- or undertreatment. This pilot study was designed to investigate the variables capable of predicting the long-term risk of mortality and living situation after surgery for ***: Patients with 70 years old and older undergoing elective surgery for CRC were prospectively enrolled in the study. The patients were preoperatively screened using 11 internationally-validated-frailty-assessment tests. The endpoints of the study were long-term mortality and living situation. The data were analyzed using univariate Cox proportional-hazard regression analysis to verify the predictive value of score indices in order to identify possible risk ***: Forty-six patients were studied. The median follow-up time after surgery was 4.6 years(range, 2.9-5.7 years) and no patients were lost to follow-up. The overall mortality rate was 39%. Four of the patients who survived(4/28, 14%) lost their functional autonomy. The preoperative impaired Timed Up and Go(TUG), Eastern Cooperative Group Performance Status(ECOG PS), Instrumental Activities of Daily Living(IADLs), Vulnerable Elders Survey(VES-13) scoring systems were significantly associated with increased long term mortality ***: Simplified frailty-assessing tools should be routinely used in elderly cancer patients before treatment in order to stratify patient risk. The TUG, ECOG-PS, IADLs and VES-13 scoring systems are potentially able to predict long-term mortality and disability. Additional studies will be needed to confirm the preliminary data in order to improve management strategies for oncogeriatric surgical patients.

关键词： Elderly geriatric assessment surgical oncology risk assessment screening tools colorectal cancer(CRC)

RICERCHE NEL SITO TARDOPALEOLITICO-MESOLITICO DI TERLAGO (Trentino) TRACCE DI STRUTTURE D'ABITATO

在线全文

学校读者我要写书评

暂无评论

Natural Disaster Reduction in China 1992年第1期 433-461页

作者： giampaolo DALMERI Museo Tridentino di Scienze Naturali

A Terlago, nel sito tardopaleolitico-mesolitico ancora in corso di scavo, sono emersedelle 《strutture》 che rispecchiano con ogni probabilità tratti dell’originario assetto abitativo. L’industrialitica riflette condizioni di giacitura sostanzialmente indisturbate. Indizi sulle modalità, insediative sonostati ricavati da resti effettivamente rilevati in situ e mediante una procedura d’indagine topografica theriguarda essenziahnente la ripartizione spaziale dell’industria, nello scavo ed in fase di elaborazione *** base alle ricerche relative all’area ispezionata, sono stati riconoscinti due importanti spazi d’uso, pro-babilmente contemporanei: A (《officina litica》) e B (《unità abitativa a grattatoi》). Sono probabilmentefrutto di uno o più intensivi momenti di frequentazione. In questo senso Terlago riproduce un modelloiusediativo a carattere semipermanente, tipo 《campo base》. A sostegno di ciò, può essere determinanteil rinvenimento di un’《impronta》, anche se piuttosto labile, di una 《paleosuperficie》 connessa ad un《margine》 di rondo capanna ed a due probabili pali. Elementi the proverebbero I’esistenza di una struttu-ra di protezione sostenuta da pall, pertinente all’《unità abitativa B》. Excavations at the Late Paleolithic-Mesolithic site of Terlago (Trento, Northern Italy).Evidence of settlement structures. Some archaeological structures have recently been discovered at thesite of Terlago still in course of excavation. The flint assemblage comes from an undisturbed *** of settlement structures derives from many flint tools recorded in situ thanks to a topographicreconstruction of the spacial distribution of the assemblages, both during the excavation and the laborato-ry study of the artefacts. Two main areas have been identified, namely: A (workshop) and B (settlementstructure with end scrapers). They both probably originated from one or more intensive period of settle-ment. According to the available data, Terlago can be interpreted as a 《base ca

关键词：排淤口布人理刀刃井段