Personalized surgical management of colorectal cancer in elderly population

作     者：Giampaolo Ugolini Federico Ghignone Davide Zattoni Giacomo Veronese Isacco Montroni 

作者机构：Department of Medical and Surgical SciencesUniversity of BolognaPoliclinico S. OrsolaMalpighi 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2014年第20卷第14期

页      面：3762-3777页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Elderly Colorectal cancer Surgery Personalized treatment Geriatric assessment 

摘      要：Colorectal cancer(CRC)in the elderly is extremely common but only a few clinicians are familiar with the complexity of issues which present in the geriatric *** this phase of the life cycle,treatment is frequently *** the fact that,nowadays,older people tend to be healthier than in previous generations,surgical undertreatment is frequently *** the other hand,surgical overtreatment in the vulnerable or frail patient can lead to unacceptable postoperative outcomes with high mortality or persistent ***,due to the geriatric patient being traditionally excluded from randomized controlled trials for a variety of factors(heterogeneity,frailty,etc.),there is a dearth of evidence-based clinical guidelines for the management of these *** objective of this review was to summarize the most relevant clinical studies available in order to assist clinicians in the management of CRC in the *** than in any other patient group,both surgical and non-surgical management strategies should be carefully individualized in the elderly population affected by *** cure and sphincter preservation are the primary goals,many other variables need to be taken into account,such as maintenance of cognitive status,independence,life expectancy and quality of life.