检索结果-南通市图书馆

A concomitant review of the effects of diabetes mellitus and hypothyroidism in wound healing

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2006年第17期12卷 2721-2729页

作者： Konstantinos A Ekmektzoglou georgios C Zografos Laboratory of Experimental Surgery and Surgical Research Athens School of Medicine AthensGreece 1st University Department of General Surgery Athens School of Medicine Hippocration HospitalAthensGreece

This paper reviews the negative impact of diabetes mellitus or hypothyroidism on wound healing, both in experimental and clinical settings. Since both are metabolic disorders of great clinical importance, special attention is given, not only to their pathophysiology, but also to their biochemical and histological effects on tissue integrity and regeneration. Also, special focus is awarded on wound healing of the gastrointestinal tract, i.e. in intestinal anastomosis, and how these disorders can lead to wound dehiscence. Since diabetes mellitus and hypothyroidism can coexist in clinical settings, more research must be directed on their influence on wound healing, considering them as one clinical entity.

关键词： Diabetes mellitus Hypothyroidism Wound healing Anastomosis

prediction of severe acute pancreatitis:Current knowledge and novel insights

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2008年第41期14卷 6273-6275页

作者： georgios I papachristou Department of Medicine Division of Gastroenterology Hepatology and Nutrition University of Pittsburgh Medical Center

Acute pancreatitis (Ap) is a common and potentially lethal acute inflammatory process with a highly variable clinical course. It is still unclear why some patients progress to organ failure and others do not. physicians, ability to predict which patients will develop severe disease is limited. Routine clinical and laboratory data and multi-factorial clinical scores measured on admission and during the first 48 h of hospitalization are currently the standards of care used to estimate the magnitude of the inflammatory response to injury. Current literature highlights several common environmental, metabolic and genetic factors that increase the risk of Ap development and subsequent adverse sequelae. Several cytokines have been found to play a critical role in the pathogenesis of Ap by driving the subsequent inflammatory response, to include tumor necrosis factor-α (TNF-α), Interleukin-1 (IL-1), IL-6 and monocyte chemotactic protein-1 (MCp-1). Large, prospective studies are still needed to address these questions by identifying Ap risk factors and serum biomarkers of severe disease.

关键词： Acute pancreatitis prediction Severity Monocyte chemotactic protein-1

A genome-wide scan for pleiotropy between bone mineral density and nonbone phenotypes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bone Research 2020年第3期8卷 356-364页

作者： Maria A.Christou georgios Ntritsos georgios Markozannes Fotis Koskeridis Spyros N.Nikas David Karasik Douglas p.Kiel Evangelos Evangelou Evangelia E.Ntzani Department of Hygiene and Epidemiology Clinical and Molecular Epidemiology UnitSchool of MedicineUniversity of loanninaloanninaGreece Department of Medicine Beth Israel Deaconess Medical CenterHarvard Medical SchoolHinda and Arthur Marcus Institute for Aging ResearchHebrew SeniorLifeand the Broad Institute of MIT&HarvardCambridgeMAUSA Azrieli Faculty of Medicine Bar llan UniversitySafedIsrael Department of Epidemiology and Biostatistics Imperial College LondonLondonUK Department of Health Services Policy and PracticeCenter for Research Synthesis in HealthSchool of Public HealthBrown UniversityProvidenceRlUSA

Osteoporosis is the most common metabolic bone disorder globally and is characterized by skeletal fragility and microarchitectural *** pleiotropy occurs when a single genetic element is associated with more than one *** aimed to identify pleiotropic loci associated with bone mineral density(BMD)and nonbone phenotypes in genome-wide association *** the discovery stage,the NHGRI-EBI Catalog was searched for genome-wide significant associations(p valueproxies of the significantly associated single nucleotide polymorphisms(SNps)(r2=1).We then assessed putative genetic associations of this set of SNps with femoral neck(FN)and lumbar spine(LS)BMD data from the GEFOS *** variants were claimed at a false discovery rateperformed among more than 400000 UK Biobank participants of European ancestry with available genetic and heel bone ultrasound *** the discovery stage,72 BMD-related pleiotropic SNps were identified,and 12 SNps located in 11 loci on 8 chromosomes were replicated in the UK *** SNps were associated,in addition to BMD,with 14 different *** pleiotropic associations were exhibited by rs479844(Ap5B1,O V O L 1 genes),which was associated with dermatological and allergic diseases,and rs4072037(M U C 1 gene),which was associated with magnesium levels and gastroenterological *** conclusion,12 BMD-related genome-wide significant SNps showed pleiotropy with nonbone *** associations can deepen the genetic understanding of bone-related diseases by identifying shared biological mechanisms with other diseases or traits.

关键词： magnesium globally Replication

An accurate model for the thin film flow

在线全文

学校读者我要写书评

暂无评论

Acta Mechanica Sinica 2008年第4期24卷 375-380页

作者： Hamid Ait Abderahmane georgios H.Vatistas Department of Mechanical and Industrial Engineering Concordia University 1455 de Maisonneuve Blvd West Montreal OC H3G 1M8 Canada

This paper deals with the linear stability of a liquid film flowing down an inclined plane. The Navier-Stokes equations were reduced into four evolution equations that describe the development of the film depth, the flow rate, the free surface velocity, and the wall shear stress, using the Karman-polhausen boundary layer integral method. Thus, we were able to determine the stability threshold and approach well the critical wave number for long waves. The obtained results were found to be in good agreement with the experiments of Liu et al.

关键词： Liquid film Linear stability Flow model

On the refracted patterns produced by liquid vortices

在线全文

学校读者我要写书评

暂无评论

Acta Mechanica Sinica 2007年第1期23卷 11-15页

作者： Yasser Aboelkassem georgios H.Vatistas McGill University MontrealQCH3A-2K6Canada Concordia University MontrealQCH3G 1M8Canada

A theoretical analysis of the refracted shadows produced by steady and time-decaying liquid vortices under uniform illumination from above is given in this article. An expression for the induced shadow intensity is derived and found to be a function of the vortex＇s free surface profile, i.e., function of the static pressure distribution. The patterns for different focusing depth are given and compared with previous visualization results from the literature. The phenomenon is examined and illustrated as a bench mark case by using both steady and time-decaying algebraic vortex models. However, this study can be extended to check the feasibility of recovering the main flow properties by analyzing the luminous image intensity of the refracted patterns. The present analysis is valid only when the swirl velocity is order of magnitude higher than the meridional flow components and the vorticity is concentrated within the core region and of intense conditions.

关键词： Fluid dynamics - Vortices - Dark shadows Intensity - Time decay

Strength, deformability and permeability of kakiritic rocks from the Gotthard base tunnel

在线全文

学校读者我要写书评

暂无评论

Journal of Rock Mechanics and Geotechnical Engineering 2023年第9期15卷 2224-2237页

作者： Martin Vogelhuber Erich pimentel georgios Anagnostou ETH Zurich ZurichSwitzerland

The 57-km long,new Gotthard Base Tunnel(GBT)crosses over a 1.1-km long stretch containing kakirites,*** rocks which,depending on the degree of tectonisation,may exhibit severe squeezing behaviour upon tunnel *** tunnel stretch was already identified as a key problem in the early planning phase,necessitating intensive geological exploration and laboratory investigations over a 14-year period,including research and development in experimental *** laboratory investigations for the GBT provided not only a considerable amount of data about the geotechnical parameters of the kakirites,but also valuable information about their basic behaviour and the adequacy of various testing techniques for this type of ***,by using specially designed testing equipment and procedures,it was shown that,(1)conventional rock mechanics triaxial tests cannot provide reliable results for kakirites;(2)the kakirites obey the principle of effective stress in Terzaghi’s classical form and consequently it is indispensable to measure the pore pressure during triaxial testing,analogously to the consolidated drained(CD)and consolidated undrained(CU)tests in soil mechanics;(3)the effects of a possible loss of water and desaturation during sampling,transport,storage and preparation of specimens can be successfully mitigated by subjecting the specimens to flow-through before the actual triaxial testing;and,(4)CD tests on partially saturated specimens that are obtained by means of flow-through can provide reliable and reproducible *** saves a significant amount of time,allows a greater number of tests to be performed,and allows results to be obtained more quickly,which is particularly important for decision-making during tunnel advance.

关键词： Squeezing pore pressure Triaxial testing

Surgical treatment of hepatic metastases from colorectal cancer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2011年第1期3卷 1-9页

作者： georgios Tsoulfas Manousos georgios pramateftakis Ioannis Kanellos Department of Surgery Aristoteleion University of ThessalonikiThessaloniki 54622Greece

Colorectal carcinoma is one of the most frequent cancers in Western societies with an incidence of around 700 per million *** half of the patients develop metastases from the primary tumor and liver is the primary metastatic *** survival rates after hepatectomy for metastatic colorectal cancer have been reported in the last few years and these may be the result of a variety of factors,such as advances in systemic chemotherapy,radiographic imaging techniques that permit more accurate determination of the extent and location of the metastatic burden,local ablation methods,and in surgical techniques of hepatic *** have led to a more aggressive approach towards liver metastatic disease,resulting in longer *** goal of this paper is to review the role of various forms of surgery in the treatment of hepatic metastases from colorectal cancer.

关键词： Hepatic metastases Colorectal cancer Liver resection

An integrated multi-criteria analysis for assessing sustainability of agricultural production at regional level

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Information processing in Agriculture 2020年第2期7卷 223-232页

作者： georgios Bartzas Kostas Komnitsas School of Mining and Metallurgical Engineering National Technical University of AthensZografos CampusAthens 15780Greece School of Mineral Resources Engineering Technical University of CreteChaniaCrete 73100Greece

Assessment of agricultural production sustainability is a multi-dimensional task that involves the quantification of various economic,social and environmental indicators at different scales and uncertainty *** this context,a particularly challenging approach is proposed involving the appropriate selection of the most representative criteria that ensure economic viability,eco-friendliness and social development,in order to overcome the limitations of other methodological approaches that are often vague and *** this study,a holistic methodology that integrates life cycle analysis(LCA),environmental risk assessment(ERA)along with on-site farm and regional surveys using the multi-criteria environment of the Analytical Hierarchy process(AHp)is designed for the identification of the most sustainable agricultural management practices at regional *** on a set of 13 representative sub-criteria,the proposed approach was applied to pistacia vera *** in Aegina island,Greece,where narrow range of resources is available,groundwater supply is scarce and of poor ***,three alternative scenarios,*** scenario representing the current production(BL)as well as Composting(CO)and Biochar Use(BU)scenarios aiming at sustainability improvement were *** of multi-criteria and sensitivity analyses suggest that the optimal sustainable management scenario is CΟ,which involves on-site composting of organic solid waste,mainly produced at farm site,and subsequent application in the *** proposed methodology shows significant potential as a valuable multi-criteria tool that can be easily adapted at regional level to assist decision makers such as farmers and their associations,policy makers,local and regional authorities to efficiently explore a range of alternative farm management practices and thus identify pathways toward sustainability.

关键词： Sustainability Multi-criteria analysis LCA AHp pistacia vera L. Sensitivity analysis

A highly concentrated vanadium protic ionic liquid electrolyte for the vanadium redox flow battery

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2021年第6期30卷 238-246,I0007页

作者： georgios Nikiforidis Amal Belhcen Mérièm Anouti Laboratoire pCM2E Universitéde ToursParc de Grandmont37200 ToursFrance LE STUDIUM Institute for Advanced Studies 45000 OrléansFrance

A protic ionic liquid is designed and implemented for the first time as a solvent for a high energy density vanadium redox flow *** being less conductive than standa rd aqueous electrolytes,it is thermally stable on a 100 ℃ temperature window,chemically stable for at least 60 days,equally viscous and dense with typical aqueous solvents and most importantly able to solubilize to 6 mol L^(-1) vanadium sulfate,thus increasing the VRFB energy density by a factor of *** measurements revealed quasi-reversible redox transitions for both catholyte and anolyte at 25 ℃ while a proof-of-concept redox flow cell with the proposed electrolyte was tested for a total of 150 cycles at 25 ℃,showing an open circuit potential of 1.39 V and energy and coulombic efficiencies of 65% and 93%,***’s more,the battery can be equally cycled at 45℃ showing good thermal *** study underlines a new route to improve the energy-to-volume ratio of energy storage system.

关键词： protic ionic liquids Redox flow battery Electrolyte High energy density