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Chronic effects of stretching on range of motion with consideration of potential moderating variables:A systematic review with meta-analysis

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Journal of Sport and Health Science 2024年第2期13卷 186-194页

作者： Andreas Konrad Shahab Alizadeh Abdolhamid Daneshjoo Saman Hadjizadeh Anvar Andrew Graham Ali Zahiri Reza Goudini Chris Edwards Carina Scharf david george Behm Institute of Human Movement Science Sport and HealthGraz UniversityGraz A-8010Austria School of Human Kinetics and Recreation Memorial University of NewfoundlandSt.John’sNL A1C 5S7Canada Department of Sport Injuries and Corrective Exercises Faculty of Sport SciencesShahid Bahonar University of KermanKerman 76169-13439Iran

Background:It is well known that stretch training can induce prolonged increases in joint range of motion(ROM).However,to date more information is needed regarding which training variables might have greater influence on improvements in ***,the purpose of this metaanalysis was to investigate the effects of stretch training on ROM in healthy participants by considering potential moderating variables,such as stretching technique,intensity,duration,frequency,and muscles stretched,as well as sex-specific,age-specific,and/or trained state-specific adaptations to stretch ***:We searched through PubMed,Scopus,Web of Science,and SportDiscus to find eligible studies and,finally,assessed the results from 77 studies and 186 effect sizes by applying a random-effect ***,by applying a mixed-effect model,we performed the respective subgroup *** find potential relationships between stretch duration or age and effect sizes,we performed a ***:We found a significant overall effect,indicating that stretch training can increase ROM with a moderate effect compared to the controls(effect size=-1.002;Z=-12.074;95%confidence interval:-1.165 to-0.840;p<0.001;I^(2)=74.97).Subgroup analysis showed a significant difference between the stretching techniques(p=0.01)indicating that proprioceptive neuromuscular facilitation and static stretching produced greater ROM than did ballistic/dynamic ***,there was a significant effect between the sexes(p=0.04),indicating that females showed higher gains in ROM compared to ***,further moderating analysis showed no significant relation or ***:When the goal is to maximize ROM in the long term,proprioceptive neuromuscular facilitation or static stretching,rather than ballistic/dynamic stretching,should be *** to consider in future research as well as sports practice is that neither volume,intensity,nor frequency of stretching were

关键词： Flexibility Long-term stretching Stretch training

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The Crities of Globalization are Wrong

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技术经济与管理研究 1998年第3期 12-15页

作者： george david (Chairman and CEO of United Technologies, U. S. A)

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Predicting lower limb periprosthetic joint infections: A review of risk factors and their classification

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世界骨科杂志：英文版 2017年第5期8卷 400-411页

作者： david A george Lorenzo Drago Sara Scarponi Enrico Gallazzi Fares S Haddad Carlo L Romano Department of Trauma and Orthopaedics University College London Hospitals Microbiological Laboratory Orthopaedic Re-search Institute Galeazzi Centre for Reconstructive Surgery and Osteoarticular Infections Orthopaedic Research Institute Galeazzi

AIM To undertook a systematic review to determine factors that increase a patient's risk of developing lower limb periprosthetic joint infections(PJI).METHODS This systematic review included full-text studies that reviewed risk factors of developing either a hip or knee PJI following a primary arthroplasty published from January 1998 to November 2016. A variety of keywords were used to identify studies through international databases referencing hip arthroplasty, knee arthroplasty, infection, and risk factors. Studies were only included if they included greater than 20 patients in their study cohort, and there was clear documentation of the statistical parameter used; specifically P-value, hazard ratio, relative risk, or/and odds ratio(OR). Furthermore a quality assessment criteria for the individual studies was undertaken to evaluate the presence of record and reporting bias. RESULTS Twenty-seven original studies reviewing risk factors relating to primary total hip and knee arthroplasty infections were included. Four studies(14.8%) reviewed PJI of the hip, 3(11.21%) of the knee, and 20(74.1%) reviewed both joints. Nineteen studies(70.4%) were retrospective and 8(29.6%) prospective. Record bias was identified in the majority of studies(66.7%). The definition of PJI varied amongst the studies but there was a general consensus to define infection by previously validated methods. The most significant risks were the use of preoperative high dose steroids(OR = 21.0, 95%CI: 3.5-127.2, P < 0.001), a BMI above 50(OR = 18.3, P < 0.001), tobacco use(OR = 12.76, 95%CI: 2.47-66.16, P= 0.017), body mass index below 20(OR = 6.00, 95%CI: 1.2-30.9, P = 0.033), diabetes(OR = 5.47, 95%CI: 1.77-16.97, P = 0.003), and coronary artery disease(OR = 5.10, 95%CI: 1.3-19.8, P = 0.017).CONCLUSION We have highlighted the need for the provider to optimise modifiable risk factors, and develop strategies to limit the impact of non-modifiable factors.

关键词： Periprosthetic joint infection Risk factor Predictive Hip arthroplasty Knee arthroplasty

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海豚10酷

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疯狂英语（初中天地） 2006年第4期 50-53页

作者： david george Gordon 芥子

超级英雄海豚让4个幸运的人相信它们可以是海洋里的最佳保护者。当时,救生员罗布·豪斯、女儿尼基还有两个朋友正在海中游泳。突然, 一家宽吻海豚围住了这些游泳者,它们用尾巴拍打着水。

关键词：海豚渔夫海洋脊椎动物

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Field Size Evaluation with a High Resolution 2D Diode Array for Variable-Aperture Collimators Used in Robotic Radiosurgery

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2023年第3期12卷 84-97页

作者： Xiaofeng Zhu Wei Nie James david george Qianyi Xu Dandan Zheng Jiajin Fan Inova Schar Cancer Institute Fairfax Virginia USA University of Rochester Medical Center Rochester NY USA

Robotic radiosurgery/Radiotherapy is increasingly adopted in clinics, and quality assurance (QA) of CyberKnife’s variable-aperture IrisTM collimators requires sub-millimeter precision. Conventional film-based QA for the 12 IrisTM cone sizes (ranging from 5 to 60 mm) is both time consuming (120 minutes for all or 30 minutes for 3 cone sizes) and highly experience dependent. To improve the efficiency, a high-resolution 2D diode detector array, sampling every 2.5 mm, was evaluated for IrisTM aperture size QA. This study focused on a spatial frequency analysis, a dose profile reconstruction, and a sensitivity study to beam size variances. Dose profiles of the 12 cones scanned with a high-resolution diode in a water tank were utilized as the gold standard for comparison. Spatial Fourier transform of these profiles were analyzed to explore applicable sampling frequency. Next, the dose profiles were artificially sampled with a 2.5 mm gap, and then interpolated using a Python-based cubic B-spline. Finally, sensitivity of the diode array system to various field sizes was measured by changing source to detector distance. We found, utilizing the diodes system, QA time was reduced to less than 10 minutes. Spatial frequency of the dose profile showed little contribution beyond 0.2 mm-1, so a Nyquist sampling of 0.4 mm-1 is appropriate for dose verification, corresponding to a 2.5 mm gap. Dose profiles were reconstructed using Cubic B-spline with good agreements to nominal for cones 7.5 mm and larger. The measured IrisTM size using the SRS MapCheck had a standard error of ±0.12 mm. Primarily, the 2D Diode array with a spatial resolution 0.4 mm-1 is appropriate for dose verification for these cones above 7.5 mm, and its application would substantially improve IrisTM QA efficiency.

关键词： CyberKnife Diode Array QA FFT

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Randomised controlled trial of triclosan coated vs uncoated sutures in primary hip and knee arthroplasty

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World Journal of Orthopedics 2019年第7期10卷 268-277页

作者： Mohamed Sukeik david george Ayman Gabr Rami Kallala Peter Wilson Fares Sami Haddad Department of Trauma and Orthopaedics University College London HospitalLondon NW1 2BUUnited Kingdom Department of Trauma and Orthopaedics Dr.Sulaiman Al-Habib Hospital–Al KhobarKing Salman Bin Abdulaziz RdAl BandariyahAl Khobar 34423Saudi Arabia Department of Clinical Microbiology UCLHLondon NW1 2PGUnited Kingdom

BACKGROUND Triclosan-coated vicryl plus suture(Ethicon, Inc.) was developed to reduce microbial colonisation during surgical procedures. However, its effect on wound healing and surgical site infections remain unclear after hip and knee arthroplasty *** To determine the effect of triclosan-coated sutures(TCS) vs non-coated sutures on wound healing, following primary hip and knee *** A single-centred, double-blind randomised controlled trial(RCT) was undertaken. We randomly allocated patients to receive either the triclosan-coated sutures(TCS vicryl plus) or non-coated sutures(NCS vicryl) during the closure of unilateral primary hip and knee arthroplasties. We utilised the ASEPSIS wound scoring system to evaluate wound healing for the first 6 weeks *** One hundred and fifty patients undergoing primary total hip or knee arthroplasty over a one-year period were included. Eighty-one were randomised to the TCS group and 69 to the NCS group. Despite no statistically significant difference in the ASEPSIS scores among the study groups(P = 0.75), sensitivity analysis using the Mann Whitney test(P = 0.036) as well as assessment of the wound complications at 6 weeks follow up, demonstrated significantly higher wound complication rates in the TCS group(8 vs 1, P = 0.03).CONCLUSION No clear advantage was demonstrated for using the TCS. However, larger multicentred RCTs are required to validate their use in hip and knee arthroplasty surgery.

关键词： Triclosan Hip Knee Replacement Arthroplasty Wound healing Complications

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用边界扫描工具检测FPGA芯片

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电子设计技术 1994年第11期 51-54+57页

作者： david george

对系统或线路板的诊断,用边界扫描检测逻辑对基于sRAM的FPGA编程,诊断结束后可重新程序化,不影响系统正常工作。

关键词：边界扫描线路板电路板 FPGA 芯片

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如果没有MiCrosoft

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中国计算机用户 1997年第6期 12-13页

作者： david＆george 王松 ObjectSoft公司 ObjectSoft公司

*** ***和*** ***是ObjeetSoft公司的两位总裁。他们同时是美国两家著名杂志《PCMagazine》和《Datamation》的资深专栏撰稿人。1997年，david和george先生将作为本刊特约海外撰稿人，为读者提供来自信息技术前沿阵地的第一手稿件。

关键词： Microsoft公司 Windows OS/2 网络操作系统 NOS 操作平台数据库管理系统 Internet服务器

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食虫者的自白

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英语沙龙（初级版） 2005年第12期 30-31页

作者： david george Gordon 马宁

大千世界,无奇不有。世界各地都有把各种虫子当作地方风味小吃的习俗,如炸知了、炸野蜂和炸蚱蜢等。不过,尽管虫子是新奇的高蛋白特色食品,在没有专家的指导或不懂得怎么吃的情况下,最好不要自己尝试烹饪虫子吃。

关键词：特色食品地方风味苹果沙司 dinner 苹果泥 eating 大黄粉虫 behind 狼蛛 lo

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当归芍药散治疗阿尔茨海默病的作用机制实验研究进展

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中国实验方剂学杂志 2022年第24期28卷 1-7页

作者：陈云慧夏军刘丹刘兴隆张天娥 david BAXTER george LIU Lizhou 游宇谢永美龚圆渊彭伟成都中医药大学成都611137 四川大学成都610041 奥塔哥大学新西兰达尼丁9054

阿尔茨海默病(AD)是一种起病隐匿并呈进行性发展的神经系统退行性疾病,已成为全球重大健康和社会经济问题。AD发病机制十分复杂,存在β淀粉样蛋白过度沉积、Tau蛋白过度磷酸化、氧化应激、炎症等多种假说,因此迫切需要多途径、多环节、... 详细信息

阿尔茨海默病(AD)是一种起病隐匿并呈进行性发展的神经系统退行性疾病,已成为全球重大健康和社会经济问题。AD发病机制十分复杂,存在β淀粉样蛋白过度沉积、Tau蛋白过度磷酸化、氧化应激、炎症等多种假说,因此迫切需要多途径、多环节、多靶点的整体综合调治措施的干预。这正是中医药的特色与优势。开展和加强中医药治疗本病的研究,具有重大意义。当归芍药散出自《金匮要略》,该方肝脾同调、血水并治,原为疗妇人之疾而设,自20世纪80年代末首次被日本学者用于治疗AD获效后,逐渐被广泛用于临床,疗效确切。阐明此方作用机理有助于其治疗优势的发挥。该文综述近年来相关实验研究进展,就其减少β-淀粉样蛋白过度沉积、抑制Tau蛋白异常磷酸化、改善氧化应激损伤、抑制炎症反应、调节乙酰胆碱相关酶类、增加α7烟碱样乙酰胆碱受体、调节脂质代谢、改善肠道菌群、拮抗神经细胞凋亡、降低胞内Ca2+超载并提高雌二醇激素水平等机制进行论述,以期为阐明此方治疗AD的科学内涵提供文献支持,并为进一步研究奠定基础。

关键词：当归芍药散阿尔茨海默病作用机制实验研究综述

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