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电力建设 2007年第6期28卷 96-97页

作者： gary l.gbur Wane Wier Torsten Bark 马明

监测磨煤机的振动值对电厂安全可靠的运行是至关重要的。美国Dynegy电厂在以往在线监测基础上选用无线方式监测,这样可以免除常规以太网或光纤电缆的安装费用,而最主要目的是加强设备的可靠性和保证人员的安全。

关键词：磨煤机振动无线振动监测

Complement-dependent neuroinflammation in spinal cord injury:from pathology to therapeutic implications

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Neural Regeneration Research 2025年第5期20卷 1324-1335页

作者： Hassan Saad Bachar El Baba Ali Tfaily Firas Kobeissy Juanmarco Gutierrez Gonzalez Daniel Refai Gerald R.Rodts Christian Mustroph David Gimbel Jonathan Grossberg Daniel l.Barrow Matthew F.gary Ali M.Alawieh Department of Neurosurgery Emory University School of MedicineAtlantaGAUSA Department of Neurology Yale UniversityNew HavenCTUSA Center for Neurotrauma Multiomics&Biomarkers(CNMB)Morehouse School of MedicineAtlantaGAUSA

Spinal cord injury remains a major cause of disability in young adults,and beyond acute decompression and rehabilitation,there are no pharmacological treatments to limit the progression of injury and optimize recovery in this *** the thorough investigation of the complement system in triggering and propagating cerebral neuroinflammation,a similar role for complement in spinal neuroinflammation is a focus of ongoing *** this work,we survey the current literature investigating the role of complement in spinal cord injury including the sources of complement proteins,triggers of complement activation,and role of effector functions in the *** study relevant data demonstrating the different triggers of complement activation after spinal cord injury including direct binding to cellular debris,and or activation via antibody binding to damage-associated molecular *** effector functions of complement have been implicated in spinal cord injury,and we critically evaluate recent studies on the dual role of complement anaphylatoxins in spinal cord injury while emphasizing the lack of pathophysiological understanding of the role of opsonins in spinal cord *** this pathophysiological review,we systematically review the different translational approaches used in preclinical models of spinal cord injury and discuss the challenges for future translation into human *** review emphasizes the need for future studies to dissect the roles of different complement pathways in the pathology of spinal cord injury,to evaluate the phases of involvement of opsonins and anaphylatoxins,and to study the role of complement in white matter degeneration and regeneration using translational strategies to supplement genetic models.

关键词： complement neuroinflammation neuroplasticity regeneration spinal cord injury targeted therapy

Chromosomal disorders and male infertility

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Asian Journal of Andrology 2012年第1期14卷 32-39,175页

作者： gary l Harton Helen G Tempest Reprogenetics Livingston NJ 07039 USA Department of Human and Molecular Genetics Herbert Wertheim College of Medicine Florida International University Miami FL 33132 USA

Infertility in humans is surprisingly common occurring in approximately 15% of the population wishing to start a family. Despite this, the molecular and genetic factors underlying the cause of infertility remain largely undiscovered. Nevertheless, more and more genetic factors associated with infertility are being identified. This review will focus on our current understanding of the chromosomal basis of male infertility specifically： chromosomal aneuploidy, structural and numerical karyotype abnormalities and Y chromosomal microdeletions. Chromosomal aneuploidy is the leading cause of pregnancy loss and developmental disabilities in humans. Aneuploidy is predominantly maternal in origin, but concerns have been raised regarding the safety of intracytoplasmic sperm injection as infertile men have significantly higher levels of sperm aneuploidy compared to their fertile counterparts. Males with numerical or structural karyotype abnormalities are also at an increased risk of producing aneuploid sperm. Our current understanding of how sperm aneuploidy translates to embryo aneuploidy will be reviewed, as well as the application of preimplantation genetic diagnosis （PGD） in such cases. Clinical recommendations where possible will be made, as well as discussion of the use of emerging array technology in PGD and its potential applications in male infertility.

关键词： chromosomal aneuploidy chromosomal translocation intracytoplasmic sperm injection in vitro fertilization male infertility non-disjunction preimplantation genetic diagnosis Y-chromosome microdeletion

Dickson Polynomials Over Finite Fields

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数学进展 1991年第1期 24-32页

作者： gary l.Mullen The Pennsylvania State University U.S.A

In this paper we will study Dickson polynomials of the first and second kinds over finite fields. For these polynomials we will discuss some known properties, point out some similarities and differences between the tw... 详细信息

关键词： Dickson Polynomials Over Finite Fields DPSK

Current understanding of the molecular mechanisms in Parkinson's disease:Targets for potential treatments

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Translational Neurodegeneration 2017年第1期6卷 256-290页

作者： Panchanan Maiti Jayeeta Manna gary l.Dunbar Field Neurosciences Institute laboratory for Restorative Neurology Mt.PleasantMI 48859USA Program in Neuroscience Mt.PleasantMI 48859USA Department of Psychology Central Michigan UniversityMt.PleasantMI 48859USA Field Neurosciences Institute St.Mary’s of MichiganSaginawMI 48604USA Department of Biology Saginaw Valley State UniversitySaginawMI 48604USA Department of Physiology University of Tennessee Health Science CenterMemphisTN 38105USA

Gradual degeneration and loss of dopaminergic neurons in the substantia nigra,pars compacta and subsequent reduction of dopamine levels in striatum are associated with motor deficits that characterize Parkinson’s disease(PD).In addition,half of the PD patients also exhibit frontostriatal-mediated executive dysfunction,including deficits in attention,short-term working memory,speed of mental processing,and *** most commonly used treatments for PD are only partially or transiently effective and are available or applicable to a minority of ***,these therapies neither restore the lost or degenerated dopaminergic neurons,nor prevent or delay the disease progression,the need for more effective therapeutics is *** this review,we provide a comprehensive overview of the current understanding of the molecular signaling pathways involved in PD,particularly within the context of how genetic and environmental factors contribute to the initiation and progression of this *** involvement of molecular chaperones,autophagy-lysosomal pathways,and proteasome systems in PD are also *** addition,emerging therapies,including pharmacological manipulations,surgical procedures,stem cell transplantation,gene therapy,as well as complementary,supportive and rehabilitation therapies to prevent or delay the progression of this complex disease are reviewed.

关键词： Parkinson’s disease Neurodegeneration Protein misfolding Molecular chaperones Cell therapy

Mitochondria as a therapeutic:a potential new frontier in driving the shift from tissue repair to regeneration

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Regenerative Biomaterials 2023年第1期10卷 1332-1355页

作者： Evan N.Main Thaiz M.Cruz gary l.Bowlin Department of Biomedical Engineering University of Memphis330 Engineering Technology BuildingMemphisTN 38152USA

Fibrosis,or scar tissue development,is associated with numerous pathologies and is often considered a worst-case scenario in terms of wound healing or the implantation of a *** that remains is a disorganized,densely packed and poorly vascularized bundle of connective tissue,which was once functional *** creates a significant obstacle to the restoration of tissue function or integration with any ***,it is of paramount importance in tissue engineering and regenerative medicine to emphasize regeneration,the successful recovery of native tissue function,as opposed to repair,the replacement of the native tissue(often with scar tissue).A technique dubbed‘mitochondrial transplantation’is a burgeoning field of research that shows promise in in vitro,in vivo and various clinical applications in preventing cell death,reducing inflammation,restoring cell metabolism and proper oxidative balance,among other reported ***,there is currently a lack of research regarding the potential for mitochondrial therapies within tissue engineering and regenerative ***,this review explores these promising findings and outlines the potential for mitochondrial transplantation-based therapies as a new frontier of scientific research with respect to driving regeneration in wound healing and host-biomaterial interactions,the current successes of mitochondrial transplantation that warrant this potential and the critical questions and remaining obstacles that remain in the field.

关键词： mitochondrial transplantation host-biomaterial integration biomaterials wound healing fibrosis

Creating a Research Enterprise Framework for Transdisciplinary Networking to Address the Food-Energy-Water Nexus

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Engineering 2022年第4期8卷 95-100页

作者： Jie Zhuang Frank E.löffler gary S.Sayler Department of Biosystems Engineering and Soil Science The University of TennesseeKnoxvilleTN 37996USA Center for Environmental Biotechnology The University of TennesseeKnoxvilleTN 37996USA Institute for a Secure and Sustainable Environment The University of TennesseeKnoxvilleTN 37996USA Department of Microbiology The University of TennesseeKnoxvilleTN 37996USA Department of Civil and Environmental Engineering The University of TennesseeKnoxvilleTN 37996USA Biosciences Division Oak Ridge National LaboratoryOak RidgeTN 37831USA

Urbanization,population growth,and the accelerating consumption of food,energy,and water(FEW)resources bring unprecedented challenges for economic,environmental,and social(EES)*** is imperative to understand the potential impacts of FEW systems on the realization of the United Nation’s Sustainable Development Goals(SDGs)as the world transitions from natural ecosystems to managed ecosystems at an accelerating rate.A major obstacle is the complexity and emergent behavior of FEW systems and associated networks,for which no single discipline can generate a holistic understanding or meaningful *** propose a research enterprise framework for promoting transdisciplinarity and top-down quantification of the interrelationships between FEW and EES *** enterprise efforts would emphasize increasing FEW resource accessibility by improving coordinated interplays across sectors and scales,expanding and diversifying supply-chain networks,and innovating technologies for efficient resource *** framework can guide the development of strategic solutions for diminishing the competition among FEW-consuming sectors in a region or country,and for minimizing existing inequalities in FEW availability when a sustainable development agenda is implemented.

关键词： Food Energy Water Stakeholder Policy Environmental sustainability

Deadly oasis:Recurrent annihilation of Cretaceous desert bryophyte colonies;the role of solar,climate and lithospheric forcing

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Geoscience Frontiers 2021年第1期12卷 1-12页

作者： Juan Pedro Rodríguez-lópeza Eduardo Barrón Daniel Peyrot gary B.Hughes Department of Geology.Faculty of Science.United Arab Emirates University.50009.Al Ain Abu DhabiUnited Arab Emirates Instituto Geológico y Minero de Espana(IGME) Ríos Rosas 23E-28003MadridSpain School of Earth and Environment University of Western Australia.6101CrawleyWestern AustraliaAustralia Centre for Energy Geosciences University of Western Australia.6101CrawleyWestern AustraliaAustralia Physics Department University of CaliforniaSanta BarbaraCA93106USA

Many oases(wet interdunes)are sedimentary systems characterized by high-frequency water-level oscillations,marked changes in salinity and intense biological activity at their *** are considered to be one of the most challenging environments on Earth for ecosystem *** dynamic,depositional settings are usually unfavourable for fossilization and subsequent preservation of vegetal *** paper describes bryophyte(liverwort)assemblages occurring in three successive horizons interpreted to represent(i)recurrent early successional phases of biological soil crust colonization of wet interdune margins or(ii)exceptional preservation of floating or riparian liverworts in oasis pond waters associated with a progressive fall of the interdune water *** record of in situ colonization surfaces characterized by delicate(***-free)three-dimensional structures represents an exceptional type of preservation herein associated with a rapid variation in phreatic interdune water level and the subsequent establishment of anoxic and reducing *** occurrence of exceptionally preserved liverwort colonies coincides with the sedimentary record of,at least,three seismite levels in the *** gathered from the site suggests that the water table of the oasis was controlled by a combination of(i)a positive creation of accommodation space due to subsidence associated with movement on syn-sedimentary extensional faults,and(ii)the rise and fall of the oasis water table controlled by the oscillations of the groundwater system due to orbital changes which appear to drive the variability of the climate *** groundwater levels flooded the oasis soil crusts and lead to the exceptional recurrent preservation of liverwort colonies at the oasis ***,considering the hypothesis of floating or riparian liverworts in the oasis pond waters,the fall in the level of the oasis water table placed the floating liverworts in contact with the

关键词： Oasis Cretaceous liverworts Colonies Extensional tectonics Solar cyclicity

Electrospun silk fibroin/poly(l-lactide-ecaplacton)graft with platelet-rich growth factor for inducing smooth muscle cell growth and infiltration

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Regenerative Biomaterials 2016年第4期3卷 239-245页

作者： Anlin Yin gary l.Bowlin Rifang luo Xingdong Zhang Yunbing Wang Xiumei Mo National Engineering Research Center for Biomaterials Sichuan UniversityChengdu 610064China Department of Biomedical Engineering University of MemphisMemphisTN 38152USA College of Chemistry Chemical Engineering and BiotechnologyDonghua UniversityShanghai 201620China

The construction of a smooth muscle layer for blood vessel through electrospinning method plays a key role in vascular tissue ***,smooth muscle cells(SMCs)penetration into the electrospun graft to form a smooth muscle layer is limited due to the dense packing of fibers and lack of inducing *** this paper,silk fibroin/poly(l-lactide-e-caplacton)(SF/PllA-Cl)vascular graft loaded with platelet-rich growth factor(PRGF)was fabricated by *** in vitro results showed that SMCs cultured in the graft grew fast,and the incorporation of PRGF could induce deeper SMCs infiltrating compared to the SF/PllA-Cl graft *** properties measurement showed that PRGF-incorporated graft had proper tensile stress,suture retention strength,burst pressure and compliance which could match the demand of native blood *** success in the fabrication of PRGF-incorporated SF/PllA-Cl graft to induce fast SMCs growth and their strong penetration into graft has important application for tissue-engineered blood vessels.

关键词： vascular graft PRGF smooth muscle cell infiltration electrospinning

电位质子滴定与NEXAFS和XPS表征功能化多壁碳纳米管比较(英文)

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催化学报 2014年第6期35卷 856-863页

作者： Zhiteng Zhang lisa Pfefferle gary l.Haller Department of Chemical and Environmental Engineering School of Engineering and Applied Science Yale University New Haven CT 06520-8286 USA

Since the discovery of carbon nanotubes (CNT), this material has been recognized as an attractive catalyst support. CNT must be functionalized before use as a catalyst support and typically this involves oxidation. However, the functional group distribution on the CNT is very complex mixture of groups and varies with oxidation agent used. Here a simple acid-base titration is introduced to characterize the oxygen functionalized CNT. By comparing characterization with near-edge X-ray absorption fine structure (NEXAFS) and X-ray photoelectron spectroscopy (XPS) for both at the C and O K-edges, it can be demonstrated that potentiometric proton titration can be a fast and quantitative analysis for Brnsted acid functional groups on CNT.

关键词：多壁碳纳米管 NEXAFS 电位滴定官能化 XPS 表征近边X射线吸收精细结构质子