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Frontiers of physics 2023年第3期18卷 59-69页

作者： gaoyang li Fuming Xu Jian Wang College of Physics and Optoelectronic Engineering Shenzhen UniversityShenzhen 518060China Department of Physics The University of Hong KongPokfulam RoadHong KongChina

We numerically investigate magnon-mediated spin transport through nonmagnetic metal/ferromagnetic insulator(NM/FI)heterostructures in the presence of Anderson disorder,and discover universal behaviors of the spin conductance in both one-dimensional(1D)and 2D *** the localized regime,the variance of logarithmic spin conductanceσ2(lnGγ)shows a universal linear scaling with its average(lnGγ),independent of Fermi energy,temperature,and system size in both 1D and 2D *** 2D,the competition between disorder-enhanced density of states at the NM/FI interface and disorder-suppressed spin transport leads to a non-monotonic dependence of average spin conductance on the disorder *** a result,in the metallic regime,average spin conductance is enhanced by disorder,and a new linear scaling between spin conductance fluctuation rms(GT)and average spin conductance GT is revealed which is universal at large system *** universal scaling behaviors suggest that spin transport mediated by magnon in disordered 2D NM/FI systems belongs to a new universality class,different from that of charge conductance in 2D normal metal systems.

关键词： universal statistical behaviors magnon-mediated spin transport disorder-enhanced spin conductance

Research on Arterial Stiffness Status in Type 2 Diabetic Patients Based on Pulse Waveform Characteristics

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Computer Modeling in Engineering & Sciences 2018年第11期117卷 143-155页

作者： gaoyang li Xiaorui Song Aike Qiao Makoto Ohta Graduate School of Biomedical Engineering Tohoku UniversitySendaiMiyagiJapan. Department of Radiology Taishan Medical UniversityNo.619 Greatwall RoadDaiyue DistrictTaianShandong271000China College of life Science and Bioengineering Beijing University of TechnologyNo.100PingleyuanChaoyang DistrictBeijing100022China Institute of Fluid Science Tohoku UniversitySendai980-8577MiyagiJapan ELyTMaX UMI 3757 CNRS-Universitéde Lyon-Tohoku UniversityJapan

For patients with type 2 diabetes,the evaluation of pulse waveform characteristics is helpful to understand changes in arterial ***,there is a lack of comprehensive analysis of pulse waveform ***,we aimed to investigate the changes in pulse waveform characteristics in patients with type 2 diabetes due to increased arterial *** this study,25 patients with type 2 diabetes and 50 healthy subjects were selected based on their clinical ***,height,weight,blood pressure,and pulse pressure were collected as the subjects’basic *** brachial-ankle pulse wave velocity(baPWV)was collected as an index of arterial *** of time[the pulse wave period(T),the relative positions of peak point(T1)and notch point(T2),and pulse wave time difference between upper and lower limbs(T3)]and area[the total waveform area(A),and the areas of the waveform before(A1)and after(A2)the notch point]were extracted from the pulse wave signals as pulse waveform *** independent sample t-test was performed to determine whether there were significant differences between ***’s correlation analysis was performed to determine the correlations between pulse waveform parameters and *** were significant differences in T3,A,A1,and A2 between the groups(p<0.05).For patients with type 2 diabetes,there were statistically significant correlations between baPWV and T3,A,A1,and A2(p<0.05).This study quantitatively assessed changes in arterial pulse waveform parameters in patients with type 2 *** was demonstrated that pulse waveform characteristics(T3,A,A1,and A2)could be used as indices of arterial stiffness in patients with type 2 diabetes.

关键词： Type 2 diabetes pulse waveform arterial stiffness.

Effect of Plaque Composition on Biomechanical Performance of a Carotid Stent: Computational Study

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Computer Modeling in Engineering & Sciences 2018年第9期116卷 455-469页

作者： Xinyang Cui Qingshuai Ren Zihao li Kun Peng gaoyang li ZhaoyongGu Aike Qiao College of life Science and Bioengineering Beijing University of TechnologyNo.100PingleyuanChaoyang DistrictBeijing100022China Institute of Mechanics Chinese Academy of ScienceNo.15BeiSiHuanWest RoadBeijing100190China Graduate School of Biomedical Engineering Tohoku UniversitySendaiMiyagiJapan

Clinical application of bare metal stents is constrained by the occurrence of instent restenosis,mainly due to the complex biomechanical environment in the *** simulation method was used to evaluate the effect of plaque composition on stent performance in a carotid *** angiography(CTA)data were used as a reference,and zero-load state of the carotid artery was used to establish a 3D stenotic artery *** plaque compositions,calcified and hypo-cellular were defined in Model 1 and Model 2,*** between the stents and arterial tissues within the stent crimping-expansion process were analyzed to explore the effects of plaque composition on the mechanical parameters of carotid *** diagram and fatigue safety factor(FSF)were analyzed to explore the effects of plaque composition on fatigue performance of a carotid stent in the stent service *** the stent crimping-expansion process,the von Mises stress in the stent and the dog-boning ratio in Model 1 were higher than that in Model *** calcified plaque prevented the stent from expanding the stenotic vessel to a pre-set ***,the risk of rupture in the calcified plaque was higher than that in the hypo-cellular *** also affected the stress/strain in the vessel wall,which was observed to be lower in Model 1 than in Model *** indicated that calcified plaque could decrease the stress-induced injury of arterial *** the stent service process,the stents used in these two models were predicted to not fail under fatigue rupture as calculated by the Goodman ***,the points closer to the fatigue limit were generally observed at the inner bend of the stent *** FSF of the stent in Model 1 was lower than that in Model *** stent operating in the presence of calcified plaques suffered high risk of *** and fatigue performance of the stent were found to be associated with plaque ***,this stud

关键词： Plaque composition biomechanical carotid stent

Visible-light-induced regioselective cross-dehydrogenative coupling of 2-isothiocyanatonaphthalenes with amines using molecular oxygen

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Science China Chemistry 2020年第11期63卷 1652-1658页

作者： Ziyu Gan Guoqing li Xiaobo Yang Qiuli Yan Guiyun Xu gaoyang li Yuan-Ye Jiang Daoshan Yang Key Laboratory of Optic-electric Sensing and Analytical Chemistry for life Science Ministry of EducationShandong KeyLaboratory of Biochemical AnalysisCollege of Chemistry and Molecular EngineeringQingdao University of Science and TechnologyQingdao 266042China School of Chemistry and Chemical Engineering Qufu Normal UniversityQufu 273165China Institute of Catalysis for Energy and Environment College of Chemistry&Chemical EngineeringShenyang Normal UniversityShenyang 110034China Qingdao West Coast New Area Poli Junior Middle School Qingdao 266409China

An efficient and eco-friendly protocol for the construction of naphtho[2,1-d]thiazol-2-amines through visible-light photoredox-catalyzed C(sp2)–H/S–H cross-dehydrogenative coupling reactions between 2-isothiocyanatonaphthalenes and amines was *** this reaction,the new C–N and C–S bonds are formed simultaneously in a single *** new method provides a straightforward approach for constructing valuable sulfur-containing compounds.

关键词： visible light cross-dehydrogenative coupling C-S bond synthetic methods metal-free

The LA-ICP-MS zircons U-Pb ages and geochemistry of the Baihua basic igneous complexes in Tianshui area of West Qinling

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Science China Earth Sciences 2007年第z2期50卷 264-276页

作者： PEI XianZhi DING SaPing ZHANG GuoWei liU HuiBin li ZuoChen li gaoyang liU ZhanQing MENG Yong Key Laboratory of Western China's Mineral Resources and Geological Engineering Ministry of Education Faculty of Earth Science and Land Resources Chang'an University Xi'an 710054 China Key Laboratory of Western China's Mineral Resources and Geological Engineering Ministry of Education Faculty of Earth Science and Land Resources Chang'an University Xi'an 710054 China State Key Laboratory of Continental Dynamics Department of Geology Northwest University Xi'an 710069 China Key Laboratory of Western China's Mineral Resources and Geological Engineering Ministry of Education Faculty of Earth Science and Land Resources Chang'an University Xi'an 710054 China

Baihua meta-igneous complex consists mainly of pyroxenite-gabbro(diorite)-diorite-quartz diorite. They form a complete comagmatic evolutionary series. The geochemical characteristics of basic-interme- diate basic igneous rocks indicate that they belong to a tholeiite suite. The REE distribution pattern is nearly flat type and LREE is slightly enriched type, and their primitive mantle-normalized and MORB-normalized trace element spider diagrams are generally similar; the liL elements (liLE) Cs, Ba, Sr, Th and U are enriched, but Rb, K and the HFSEs Nb, P, Zr, Sm, Ti and Y are relatively depleted. All these show comagmatic evolution and origin characteristics. The tectonics environment discrimination of trace element reveals that these igneous complexes formed in an island-arc setting. The LA-ICP-MS single-zircons U-Pb age of Baihua basic igneous complex is 434.6±1.5 Ma (MSWD = 1.3), which proves that the formation time of the island-arc type magmatite in the northern zone of West Qinling is Late Ordovician or Early Silurian, also reveals that the timing of subduction of paleo-ocean basin represented by the Guanzizhen ophiolite and resulting island-arc-type magmatic activities is probably Middle-Late Ordovician to Early Silurian.

关键词： basic igneous complex, island-arc setting, LA-ICP-MS, zircons U-Pb isotopic ages, Tianshui area, West Qinling

Safety evaluation and whole genome sequencing for revealing the ability of Penicillium oxalicum WX-209 to safely and effectively degrade citrus segments

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Food Science and Human Wellness 2023年第6期12卷 2369-2380页

作者： Xiao Hu Yujiao Qian Zhipeng Gao gaoyang li Fuhua Fu Jiajing Guo Yang Shan Hunan Agriculture Product Processing Institute International Joint Lab on Fruits&Vegetables ProcessingQuality and SafetyHunan Key Lab of Fruits&Vegetables StorageProcessingQuality and SafetyHunan Academy of Agricultural SciencesChangsha 410125China College of Animal Science and Technology Hunan Agricultural UniversityChangsha 410128China

The microbial potential of Penicillium has received critical *** present research aimed to elucidate the efficacy of crude enzyme secreted from Penicillium oxalicum WX-209 in degrading citrus segments and evaluate the safety of the *** showed that citrus segment membranes gradually dissolved after treatment with the crude enzyme solution,indicating good degradation *** significant differences in body weight,food ingestion rate,hematology,blood biochemistry,and weight changes of different organs were found between the enzyme intake and control *** experiments showed that the crude enzyme had high biological ***,the whole genome of *** WX-209 was sequenced by PacBio and Illumina ***-five scaffolds were assembled to generate 36 Mbp size of genome sequence comprising 11369 predicted genes modeled with a GC content of 48.33%.A total of 592 genes were annotated to encode enzymes related to carbohydrates,and some degradation enzyme genes were identified in strain *** WX-209.

关键词： Penicillium oxalicum WX-209 Crude enzyme Degradation Safety evaluation Genome sequencing

Citrus aurantium L. extract alleviate depression by inhibiting gut microbiota-mediated inflammation in mice

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Food Science and Human Wellness 2024年第6期13卷 3403-3414页

作者： Tao li Guirong Zeng lingfeng Zhu Yanyang Wu Qun Zhang Fuhua Fu Donglin Su gaoyang li Qili li Yang Shan Hunan Agricultural Product Processing Institute Hunan Academy of Agricultural SciencesChangsha 410125China Hunan Key Laboratory of Pharmacodynamics and Safety Evaluation of New Drugs Hunan Provincial Research Drugs Safety Evaluation Research CenterChangsha 410331China College of Food Science and Technology Hunan Agricultural UniversityChangsha 410128China

Gut microbiota plays a crucial role in the pathophysiology of *** study aimed to explore the antidepressant effect of mature whole Citrus aurantium fruit extract(FEMC)in the chronic unpredictable mild stress(CUMS)*** behavioral tests were applied to assess antidepressant effect and 16S rRNA sequencing was used to analyze the changes of gut *** results showed that the major components of FEMC were naringin and neohesperidin and significantly increased the sucrose preference index of the *** also could reduce the feeding latency in an open field test and the rest time in a novelty suppressed feeding *** addition,FEMC could increase CUMS-induced reduction in the levels of BDNF,PSD95,and SYN in the ***,FEMC intervention slightly decreased the ratio of Firmicutes to ***,FEMC reduced the abundance of the Prevotellaceae_Ga6A1_group,[Ruminococcus]_torques_group,which have been reported to be closely related to *** analysis revealed that mitogen-activated protein kinase(MAPK)signaling pathway and lipopolysaccharide biosynthesis were involved in the anti-inflammatory effect of FEMC in the CUMS animal ***,the EliSA results showed that FEMC could significantly reduce the expression of pro-inflammatory cytokines IL-6 and TNF-αin the serum of depressive *** results suggest FEMC can am eliorate depressive behavior by i nhibiting gut microbiota-mediated inflammation in mice.

关键词： Citrus aurantium L. Chronic unpredictable mild stress Depression Flavonoids Gut microbiota

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柑橘工业国际标准体系建设研究

中国食品学报 2014年第6期14卷 1-8页

作者：单杨刘伟李高阳湖南省农业科学院湖南省农产品加工研究所长沙410125 柑橘资源综合利用国家地方联合工程实验室长沙410125 国家柑橘加工产业技术创新战略联盟长沙410125 中南大学隆平分院长沙410125

本文系统分析了世界主要国际组织(CAC、ISO)、主要贸易国家和地区(美国、日本、欧盟)的柑橘及制品标准、法规体系构成及现状,并与我国标准进行对比分析,对我国柑橘工业标准体系建设提出建议。

关键词：柑橘标准体系建设

西方遇见东方——斯洛特、蒙培元情感价值体系比较

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社会科学 2014年第5期 124-130页

作者：李高阳浙江大学哲学系迈阿密大学哲学系

在当代哲学中,中西哲学均有某种"情感的转向"。其最新进展,斯洛特是西方哲学中最重要的代表之一,而蒙培元则是中国哲学中最重要的代表。第一,他们分别从西方内部和东方外部反思西方(启蒙)理性主义哲学那种割裂情感与理性的传统,共同主... 详细信息

在当代哲学中,中西哲学均有某种"情感的转向"。其最新进展,斯洛特是西方哲学中最重要的代表之一,而蒙培元则是中国哲学中最重要的代表。第一,他们分别从西方内部和东方外部反思西方(启蒙)理性主义哲学那种割裂情感与理性的传统,共同主张情感与理性的统一。第二,他们都站在情感价值观立场上,分别采取重新阐释哲学、构建情感价值体系的方法:斯洛特基于生活本身有价值假定,以"容生心"超越、融合、平衡启蒙理性价值;蒙培元则回归中国哲学"生生之道、生生之理—良心"的形而上传统。其中,"容生心"和"良心"作为最基本的价值"相遇",双方价值体系可相互借鉴。第三,他们将这种情感主义价值理性体系应用于社会政治领域和自然环境领域形成了各自新的情感型正义观和生态观。

关键词：反思启蒙理性浮士德情感价值容生心良心

用正己烷-乙醇-水三元双液相从亚麻籽提油脱氰苷

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农业工程学报 2006年第12期22卷 205-210页

作者：李高阳丁霄霖江南大学食品学院

采用正己烷-乙醇-水三元双液相体系进行同时提取亚麻籽中油脂和脱除氰苷的研究,通过单因素试验和响应面分析进行优化,确定的优化提取条件为:料醇比为1∶3.4;料烷比为1∶5.4;提取时间为78.5 m in;N aOH浓度为0.12%;温度为55℃;乙醇浓度为... 详细信息

采用正己烷-乙醇-水三元双液相体系进行同时提取亚麻籽中油脂和脱除氰苷的研究,通过单因素试验和响应面分析进行优化,确定的优化提取条件为:料醇比为1∶3.4;料烷比为1∶5.4;提取时间为78.5 m in;N aOH浓度为0.12%;温度为55℃;乙醇浓度为85%。结果表明:正己烷-乙醇-水双液相体系对亚麻籽具有很好的提油和脱氰苷的作用,在优化条件下亚麻籽油提取率达45.1%,亚麻氰苷脱除率96.8%。

关键词：亚麻籽双液相萃油脱氰苷响应面