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Body mass index and serum lipid profile influence serum prostate-specific antigen in Chinese men younger than 50 years of age

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Asian Journal of Andrology 2011年第4期13卷 640-643页

作者： Ming Liu Jian-Ye wang Ling Zhu gang wan Department of Urology Beijing Hospital No. 1 Dahua Road Dongcheng District Beijing 100730 China Health Assessment Center Beijing Hospital NO.1 Dahua Road Dongcheng District Beijing 100730 China Medical Statistics Department Ditan Hospital No. 13 Ditan Street Dongcheng District Beijing 100015 China

This study is to assess the potential factors that could affect the serum prostate-specific antigen （PSA） level in healthy younger men. We evaluated the associations of age, body mass index （BMI） and serum lipid profile with serum PSA level in 6774 Chinese men （aged 20-49 years） who received a routine health examination. Eligible men were classified into 10-year age groups, BMI was categorized as underweight （〈18.5）, normal （18.5-22.9）, overweight （23.0-24.9）, obese （25.0-29,9） and very obese （〉30） according to the redefined World Health Organization （WHO） criteria for the Asia-Pacific region. PSA levels were compared among groups as well, In multiple linear regression analysis, PSA was positively correlated with age （P〈0.0001）. Negative correlations existed between PSA and BMI （P〈0.0001） and triglyceride level （P=0.01）. No relationship could be found between PSA and serum cholesterol （P=0.711） or high-density lipoprotein （HDL; P =0.665）. In addition, we found that serum PSA levels increased with age and decreased with BMI. Our study demonstrates that age, BMI and triglyceride levels influence the PSA level in men 〈50 years of age.

关键词： age body mass index prostate-specific antigen serum lipid profile

Spontaneous emission fromΛ-type three-level atom driven by bichromatic field in anisotropic double-band photonic crystals

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Chinese Physics B 2023年第4期32卷 389-396页

作者：凌凯姜丽万仁刚姚治海 Changchun University of Science and Technology Changchun 130000China School of Physics and Information Technology Shaanxi Normal UniversityXi’an 710062China

The spontaneous emission property ofΛ-type three-level atom driven by the bichromatic field in the anisotropic double-band photonic crystal is calculated by n-times iteration *** influence of different parameters on atomic spontaneous emission is studied,and the phenomena of atomic spontaneous emission are explained in the dressed state *** is found that the spontaneous emission spectra of the atom driven by the bichromatic field presents a multi-peak comb *** position of the emission peak is determined by the initial state of the atom,and the interval between the neighboring emission peaks is the detuningδof the bichromatic *** the ratio between Rabi frequency intensity and the detuningδof the bichromatic field remains unchanged,the intensity of each emitted peak remains *** spontaneously emitted peak can be annihilated in the band gap and enhanced near the band edge in the anisotropic photonic ***,we also observe the fluorescence quenching phenomenon in the spontaneous emission *** research in this paper provides the theoretical guidance for the control of atomic spontaneous emission.

关键词： photonic crystal bichromatic field spontaneous emission spectra dressed state

Performance analysis of BDS-3 Klobuchar model

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Performance analysis of BDS-3 Klobuchar model

Production and Characterization of Monoclonal Antibodies of Shrimp White Spot Syndrome Virus Envelope Protein VP28

第十四届中国卫星导航年会

作者： Yongxing Zhu gang wan Xianggao Yan State Key Laboratory of Geo-information Engineering Xi'an Research Institute of Survey and Mapping National Space Science Center Chinese Academy of Sciences School of Space Information Space Engineering University College of Geological Engineering and Geomatics Chang'an University

Since July 2020, the global Beidou Navigation Satellite System(BDS-3) satellites provide new B1C and B2a public navigation service signals,as well as the legacy B1I and B3I signals. With the opening of BDS-3 system global service, the service area of the broadcast Klobuchar model(BDSKlob)parameters expanded from China and parts of the Asia-Pacific region to the whole world. In this study, the differences between the GPS Klobuchar model(GPSKlob) and the BDSKlob is comprehensively analyzed. The data since the opening of the BDS-3 is collected, and the results show that:(1) the average correction accuracy of the BDSKlob model in global-scale is about 4.61-5.75TECU;(2) the correction abnormalities of the modifed BDSKlob model in high latitude region has been improved significantly;(3) the interchangeability between the BDSKlob and the GPSKlob model algorithm has been verified, is initially verified.

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中国病毒学 2007年第1期22卷 21-25页

作者： wan-gang GU Jun-fa YUAN Ge-lin XU Li-juan LI Ni LIU Cong ZHANG Jian-hong ZHANG Zheng-li SHI State Key Laboratory of Virology Wuhan Institute of Virology Chinese Academy of Sciences Wuhan 430071 China Wuhan Institute of Biological Products Ministry of Health Wuhan 430060 China College of Life Science Central China Normal University Wuhan 430079 China

BALB/c 老鼠与净化的白点症候群病毒(WSSV ) 被使免疫。六根 monoclonal 抗体房间线被 ELISA 选择， VP28 蛋白质在 E 表示了。coli。在 vitro 中立化，实验证明他们中的 4 个能在喇蛄禁止病毒感染。西方污点建议所有这些 monoclonal ... 详细信息

BALB/c 老鼠与净化的白点症候群病毒(WSSV ) 被使免疫。六根 monoclonal 抗体房间线被 ELISA 选择， VP28 蛋白质在 E 表示了。coli。在 vitro 中立化，实验证明他们中的 4 个能在喇蛄禁止病毒感染。西方污点建议所有这些 monoclonal 抗体对 VP28 的 conformational 结构。monoclonal 抗体 7B4 用胶体的金粒子被标记并且过去常由标记的 immunogold 在病毒信封上定位 VP28。这些 monoclonal 抗体能被用来为 WSSV 感染开发免疫学的诊断方法。关键词怀特点症候群病毒(WSSV )- Mab - 信封 - 本地化 - 中立化 CLC 数字 S945.

关键词： White spot syndrome virus (WSSV) Mab Envelope Localization Neutralization

A Study on Measurement of Forest Soil Redox Potential

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Journal of Analytical Sciences, Methods and Instrumentation 2013年第3期3卷 137-151页

作者： Mu Liu Chengde Luo Xiaoyun Liu gang wan Bin Dai College of Forestry Sichuan Agricultural University Ya’an China College of Forestry Sichuan Agricultural University Ya’an China&Promotion Center of Forestry Technology Forestry Bureau of Fushun County Fushun China. Promotion Center of Forestry Technology Forestry Bureau of Fushun County Fushun China.

Redox potential has principal influences on formation and attribute of soils and it is necessary to research the measurement of soil redox potential. The self-made potentiometer and two indigenous FJA-5 potentiometers were employed to measure the Eh values of fir forest soils in situ, which lied in Savage Sea Beauty Spot in Sichuan Province. Simultaneously fresh soils in situ were collected and made into suspensions with various soil-water ratios and standing time to measure Eh values. The results demonstrated that the total tendency of Eh values measured by the self-made potentiometer was gradually falling with soil-water ratios increasing and standing time prolonging. There is a great difference between Eh values measured in laboratory and in situ. Only in situ may the measured Eh values show realistic oxidation-reduction conditions and formation characteristics of forest soil. The self-made potentiometer has a preferable performance than indigenous FJA-5 potentiometers and it can be applied to measuring forest soil Eh in situ.

关键词： The Self-Made Potentiometer Redox Conditions Suspensions Soil-Water Ratios and Standing Time

Mutual regulation of microglia and astrocytes after Gas6 inhibits spinal cord injury

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Neural Regeneration Research 2025年第2期20卷 557-573页

作者： Jiewen Chen Xiaolin Zeng Le wang Wenwu Zhang gang Li Xing Cheng Peiqiang Su Yong wan Xiang Li Department of Spine Surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Guangdong Province Key Laboratory of Orthopedics and Traumatology GuangzhouGuangdong ProvinceChina

Invasive inflammation and excessive scar formation are the main reasons for the difficulty in repairing nervous tissue after spinal cord *** and astrocytes play key roles in the spinal cord injury micro-environment and share a close ***,the mechanisms involved remain *** this study,we found that after spinal cord injury,resting microglia(M0)were polarized into pro-inflammatory phenotypes(MG1 and MG3),while resting astrocytes were polarized into reactive and scar-forming *** expression of growth arrest-specific 6(Gas6)and its receptor Axl were significantly down-regulated in microglia and astrocytes after spinal cord *** vitro experiments showed that Gas6 had negative effects on the polarization of reactive astrocytes and pro-inflammatory microglia,and even inhibited the cross-regulation between *** further demonstrated that Gas6 can inhibit the polarization of reactive astrocytes by suppressing the activation of the Yes-associated protein signaling ***,in turn,inhibited the polarization of pro-inflammatory microglia by suppressing the activation of the nuclear factor-κB/p65 and Janus kinase/signal transducer and activator of transcription signaling *** vivo experiments showed that Gas6 inhibited the polarization of pro-inflammatory microglia and reactive astrocytes in the injured spinal cord,thereby promoting tissue repair and motor function ***,Gas6 may play a role in the treatment of spinal cord *** can inhibit the inflammatory pathway of microglia and polarization of astrocytes,attenuate the interaction between microglia and astrocytes in the inflammatory microenvironment,and thereby alleviate local inflammation and reduce scar formation in the spinal cord.

关键词： astrocytes Axl cell polarization Gas6 Hippo signal inflammatory micro-environment intercellular interaction microglia single-cell sequencing spinal cord injury

Effects of 1,2,4-Trichlorobenzene and Mercury Ion Stress on Ca^2+ Fluxion and Protein Phosphorylation in Rice

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Rice science 2007年第4期14卷 272-282页

作者： GE Cai-lin wanG Ze-gang wan Ding-zhen DING Yan wanG Yu-long SHANG Qi LUO Shi-shi MA Fei Jiangsu Provincial Key Laboratory of Crop Genetics and Physiology Yangzhou University Yangzhou 225009 China

The effects of 5 mg/L 1,2,4-trichlorobenzene （TCB） and 0.1 mmol/L mercury ion （Hg^2＋） stresses on Ca^2＋ fluxion and protein phosphorylation in rice seedlings were investigated by isotope exchange kinetics and in vitro phosphorylation assay. The Ca^2＋ absorption in rice leaves and Ca^2＋ transportation from roots to leaves were promoted significantly in response to Hg^2＋ and TCB treatments for 4-48 h. The Ca^2＋ absorption peaks presented in the leaves when the rice seedlings were exposed to Hg^2＋ for 8-12 h or to TCB for 12-24 h. Several Ca^2＋ absorption peaks presented in the roots during rice seedlings being exposed to Hg^2＋ and TCB, and the first Ca^2＋ absorption peak was at 8 h after being exposed to Hg^2＋ and TCB The result of isotope exchange kinetic analysis confirmed that short-term （8 h） Hg^2＋ and TCB stresses caused Ca^2＋ channels or pumps located on plasmalemma to open transiently. The phosphorylation assay showed that short-term TCB stress enhanced protein phosphorylation in rice roots （TCB treatment for 4-8 h） and leaves （TCB treatment for 4-24 h）, and short-term （4-8 h） Hg^2＋ stress also enhanced protein phosphorylation in rice leaves. The enhancement of protein phosphorylation in both roots and leaves corresponded with the first Ca^2＋ absorption peak, which confirmed that the enhancement of protein phosphorylation caused by TCB or Hg^2＋ stress might be partly triggered by the increases of cytosolic calcium. TCB treatment over 12 h inhibited protein phosphorylation in rice roots, which might be partly due to that TCB stress suppressed the protein kinase activity. Whereas, Hg^2＋ treatment inhibited protein phosphorylation in rice roots, and Hg^2＋ treatment over 12 h inhibited protein phosphorylation in rice leaves. This might be attributed to that not only the protein kinase activity, but also the expressions of phosphorylation proteins were restrained by Hg^2＋ stress.

关键词： rice mercury ion 1,2,4-trichlorobenzene calcium ion fluxion protein phosphorylation

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地图空间认知的数学基础

测绘学报 2021年第6期50卷 726-738页

作者：万刚武易天航天工程大学航天信息学院北京101416 航天工程大学研究生院北京101416

地图作为人类认知客观世界的重要工具,它的出现和发展极大提升了人们获取地理空间知识的效率。地图设计、虚拟地理环境、地理信息系统及新型智能化地图的研究都离不开地图空间认知理论的指导。本文提出地图空间认知应基于数学基础进行... 详细信息

地图作为人类认知客观世界的重要工具,它的出现和发展极大提升了人们获取地理空间知识的效率。地图设计、虚拟地理环境、地理信息系统及新型智能化地图的研究都离不开地图空间认知理论的指导。本文提出地图空间认知应基于数学基础进行研究的观点,并对多种地图空间认知数学模型进行归纳和总结,为地图空间认知研究提供了新视角。

关键词：地图空间认知数学基础认知计算

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地理空间信息网格的历史演变与思考

测绘学报 2016年第B12期45卷 15-22页

作者：万刚曹雪峰信息工程大学地理空间信息学院河南郑州450052

网格的概念随着科学技术和社会实践的发展而不断演变,在不同行业中的内涵既有区别又有联系。本文首先分析了地理空间网格的基本特征,提出了地理空间网格的广义和狭义概念。然后,回顾分析了地理空间网格的发展历史,认为地理空间网格是一... 详细信息

网格的概念随着科学技术和社会实践的发展而不断演变,在不同行业中的内涵既有区别又有联系。本文首先分析了地理空间网格的基本特征,提出了地理空间网格的广义和狭义概念。然后,回顾分析了地理空间网格的发展历史,认为地理空间网格是一种人类空间认知的重要思想和理论、方法,地理空间信息网格是信息化条件下的地理空间网格。最后,分析指出了地理空间信息网格以信息化的地球系统为研究对象,以模型理论为基础理论,未来将发展出现代地理空间网格的标准体系和服务体系,不仅服务于人,还将服务于智能化平台,具有广阔发展前景。

关键词：地理空间信息网格空间认知地图投影地理信息系统虚拟地理环境数字地球