Body mass index and serum lipid profile influence serum prostate-specific antigen in Chinese men younger than 50 years of age
Body mass index and serum lipid profile influence serum prostate-specific antigen in Chinese men younger than 50 years of age作者机构：Department of Urology Beijing Hospital No. 1 Dahua Road Dongcheng District Beijing 100730 China Health Assessment Center Beijing Hospital NO.1 Dahua Road Dongcheng District Beijing 100730 China Medical Statistics Department Ditan Hospital No. 13 Ditan Street Dongcheng District Beijing 100015 China
出 版 物：《Asian Journal of Andrology》 (亚洲男性学杂志（英文版）)
年 卷 期：2011年第13卷第4期
页 面：640-643页
核心收录：
学科分类：090603[农学-临床兽医学] 090502[农学-动物营养与饲料科学] 1002[医学-临床医学] 0905[农学-畜牧学] 09[农学] 0906[农学-兽医学]
基 金：a grant from Capital Key Clinical Technology Research China
主 题：age body mass index prostate-specific antigen serum lipid profile
摘 要：This study is to assess the potential factors that could affect the serum prostate-specific antigen （PSA） level in healthy younger men. We evaluated the associations of age, body mass index （BMI） and serum lipid profile with serum PSA level in 6774 Chinese men （aged 20-49 years） who received a routine health examination. Eligible men were classified into 10-year age groups, BMI was categorized as underweight （〈18.5）, normal （18.5-22.9）, overweight （23.0-24.9）, obese （25.0-29,9） and very obese （〉30） according to the redefined World Health Organization （WHO） criteria for the Asia-Pacific region. PSA levels were compared among groups as well, In multiple linear regression analysis, PSA was positively correlated with age （P〈0.0001）. Negative correlations existed between PSA and BMI （P〈0.0001） and triglyceride level （P=0.01）. No relationship could be found between PSA and serum cholesterol （P=0.711） or high-density lipoprotein （HDL; P =0.665）. In addition, we found that serum PSA levels increased with age and decreased with BMI. Our study demonstrates that age, BMI and triglyceride levels influence the PSA level in men 〈50 years of age.
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