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Chinese Journal of Aeronautics 2021年第4期34卷 253-264页

作者： Hao CHEN Hui WANG Ali ABD el-ATY Yao QIN Jiang LI Yong ZHANG Tao LI Xunzhong GUO college of Material Science and Technology Nanjing University of Aeronautics and AstronauticsNanjing 211100China college of Mechanical and electrical Engineering Nanjing University of Aeronautics and AstronauticsNanjing 210016China Jiangsu Key Laboratory of Nuclear Energy Equipment Materials Engineering Nanjing University of Aeronautics and AstronauticsNanjing 211100China Mechanical Engineering Department Faculty of Engineering-HelwanHelwan UniversityCairoEgypt Nanjing Golden Dragon Bus co. LtdNanjing 210012China

In the 3 D free bending forming system,the bending die can be designed either in a sliding type or rolling friction *** die-based sliding friction type is often called normal bending dies;however,the bending dies-based rolling friction type includes bending die-based roller type and ball type in *** the current study,the impact of three bending dies on the forming force,and the bent tube quality was *** obtained results showed that the tangential stresses and strains of the tubes formed by the bending die-based roller type were the smallest among the three bending ***,the spherical bearing force PUwas reduced drastically after using the roller type and ball type compared to the sliding friction ***,the uniformity of the wall thickness distribution of the tubes formed by the roller type and ball type was better than those obtained from the sliding friction *** addition,the cross-section distortion rate was reduced by 2.8%using the roller type,and 1.8%using ball-type compared to the sliding friction type.

关键词： Bending die Cross-section distortion Rolling friction Sliding friction Spherical bearing force Wall thickness

Biological and molecular studies on specific immune cells treated with checkpoint inhibitors for the thera-personal approach of breast cancer patients(ex-vivo study)

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Oncology Research 2021年第5期29卷 319-330页

作者： MOTAWA E.el-HOUSEINI MOSTAFA S.ARAFAT AHMED M.el-HUSSEINY ISLAM M.KASEM MAHMOUD M.KAMel AHMED H.el-HABASHY MEDHAT M.KHAFAGY ENAS M.RADWAN MAHA H.HelAL MONA S.ABDelLATEIF Medical Biochemistry and Molecular Biology Cancer Biology DepartmentNational Cancer InstituteCairo UniversityCairo11976Egypt Biotechnology Department Faculty of ScienceCairo UniversityGiza12613Egypt Zoology department Faculty of ScienceCairo UniversityGiza12613Egypt Clinical Pathology Department National Cancer InstituteCairo UniversityCairo11976Egypt Department of Pathology National Cancer InstituteCairo UniversityCairo11976Egypt Surgical Oncology Department National Cancer InstituteCairo UniversityCairo11976Egypt Radio-Diagnosis Department National Cancer InstituteCairo UniversityCairo11976Egypt

Immunotherapy becomes a promising line of treatment for breast cancer(BC)however,its success rate is still ***:The study was designed to optimize the condition for producing an effective dendritic cell(DCs)based immunotherapy by using DCs and T lymphocytes together with tumor-inﬁltrating lymphocytes(TILs)and tumor-inﬁltrating DCs(TIDCs),treated with anti-PD1 and anti-CTLA4 monoclonal *** mixture of immune cells was co-cultured with autologous breast cancer cells(BCCs)isolated from 26 BC ***:There was a signiﬁcant upregulation of CD86 and CD83 on DCs(p=0.001 and 0.017,respectively),similarly upregulation of CD8,CD4 and CD103 on T cells(p=0.031,0.027,and 0.011,respectively).While there was a signiﬁcant downregulation of FOXP3 and combined ***8 expression on regulatory T cells(p=0.014 for both).Increased CD8/Foxp3 ratio(pely).There was a signiﬁcant increase in interferon-γ(IFN-γ,pelial growth factor(VEGF,pell death ligand 1(PDL-1)were downregulated in BCCs(pell death 1(PD-1,pells(DCs,T cells,TIDCs,and TILs)with immune checkpoint inhibitors could produce a potent and effective BC ***,these data should be validated on an experimental animal model to be transferred to the clinical setting.

关键词： Immunotherapy breast cancer PD1 CTLA4 TIDCs TILs

Development of Cd-doped co Nanoparticles Encapsulated in Graphite Shell as Novel electrode Material for the Capacitive Deionization Technology

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Nano-Micro Letters 2013年第4期5卷 303-313页

作者： Nasser A.M.Barakat Khalil Abdelrazek Khalil Ahmad G.el-Deen Hak yong kim Organic Materials and Fiber Engineering Department Chonbuk National University Chemical Engineering Department Minia University Mechanical Engineering Department (NPST) King Saud University Dept of Bionano System Engineering College of Engineering Chonbuk National University

Because of the low energy requirement and the environmentally safe byproducts, the capacitive deionization water desalination technology has attracted the attention of many researchers. The important requirements for electrode materials are good electrical conductivity, high surface area, good chemical stability and high specific capacitance. In this study, metallic nanoparticles that are encapsulated in a graphite shell(Cd doped co/C NPs) are introduced as the new electrode material for the capacitive deionization process because they have higher specific capacitance than the pristine carbonaceous materials. Cd doped co/C NPs perform better than graphene and the activated carbon. The introduced nanoparticles were synthesized using a simple sol gel technique. A typical sol gel composed of cadmium acetate, cobalt acetate and poly(vinyl alcohol)was prepared based on the polycondensation property of the acetates. The physiochemical characterizations that were used confirmed that the drying, grinding and calcination in an Ar atmosphere of the prepared gel produced the Cd doped co nanoparticles, which were encapsulated in a thin graphite layer. Overall, the present study suggests a new method to effectively use the encapsulated bimetallic nanostructures in the capacitive deionization technology.

关键词： Capacitive deionization Water desalination Bimetallic nanoparticles Specific capacitance

The REMO Ocean Data Assimilation System into HYcoM(RODAS_H):General Description and Preliminary Results

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Atmospheric and Oceanic Science Letters 2014年第5期7卷 464-470页

作者： Clemente Augusto Souza TANAJURA Alex Novaes SANTANA Davi MIGNAC Leonardo Nascimento lima Konstantin BelYAEV XIE Ji-Ping Physics Institute Federal University of Bahia (UFBA) Salvador 40170-280 Brazil Oceanographic Modeling and Observation Network (REMO) Center for Research in Geophysics and Geology Federal University of Bahia (UFBA) Salvador 40170-280 Brazil Ocean Sciences Department University of California Santa Cruz (UCSC) USA Graduate Program in Geophysics Federal University of Bahia (UFBA) Salvador Brazil Shirshov Institute of Oceanology Russian Academy of Sciences (SHIRSHOV/RAS) Moscow Russia Institute of Atmospheric Physics(IAP) Chinese Academy of Sciences (CAS)

The first version of the Brazilian Oceano- graphic Modeling and Observation Network （REMO） ocean data assimilation system into the Hybrid coordi- nate Ocean Model （HYcoM）（RODAS H） has recently been constructed for research and operational purposes. The system is based on a multivariate Ensemble Optimal Interpolation （EnOI） scheme and considers the high fre- quency variability of the model error co-variance matrix. The EnOl can assimilate sea surface temperature （SST）, satellite along-track and gridded sea level anomalies （SLA）, and vertical profiles of temperature （T） and salinity （S） from Argo. The first observing system experiment was carried out over the Atlantic Ocean （78°S-50°N, 100°W-20°E） with HYcoM forced with atmospheric reanalysis from 1 January to 30 June 2010. Five integra- tions were performed, including the control run without assimilation. In the other four, different observations were assimilated： SST only （A SST）; Argo T-S profiles only （AArgo）; along-track SLA only （A_SLA）; and all data employed in the previous runs （A_All）. The A_SST, A_Argo, and A_SLA runs were very effective in improv- ing the representation of the assimilated variables, but they had relatively little impact on the variables that were not assimilated. In particular, only the assimilation of S was able to reduce the deviation of S with respect to ob- servations. Overall, the A_All run produced a good analy- sis by reducing the deviation of SST, T, and S with respect to the control run by 39%, 18%, and 30%, respectively, and by increasing the correlation of SLA by 81%.

关键词： ocean data assimilation ensemble optimalinterpolation observing system experiment HYcoM Atlantic Ocean

Multi‑Functional Fibrous Dressings for Burn Injury Treatment with Pain and Swelling Relief and Scarless Wound Healing

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Advanced Fiber Materials 2023年第6期5卷 1963-1985页

作者： Zhengchao Yuan Yue Zhao Muhammad Shafiq Jiahui Song Jing Hou Yuqing Liang Xiao Yu Yujie Chen Fan Yu Mohamed el‑Newehy Hany el‑Hamshary Yosry Morsi Shichao Jiang Hui Zheng Xiumei Mo State Key Laboratory for Modification of Chemical Fibers and Polymer Materials Shanghai Engineering Research Center of Nano‑Biomaterials and Regenerative MedicineCollege of Biological Science and Medical EngineeringDonghua UniversityShanghai 201620People’s Republic of China Department of Chemical Engineering Faculty of EngineeringGraduate SchoolKyushu UniversityFukuoka 819‑0395Japan United Graduate School of Drug Discovery and Medical Information Sciences Gifu University1‑1 YanagidoGifu 501‑1193Japan Department of Orthopedics Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinan 250021People’s Republic of China Department of Chemistry College of ScienceKing Saud UniversityP.O.Box 245511451 RiyadhSaudi Arabia Faculty of Engineering and Industrial Sciences Swinburne University of TechnologyBoroondaraVIC 3122Australia Medical Science and Technology Innovation Center Shandong First Medical University&Shandong Academy of Medical SciencesJinan 250117People’s Republic of China Department of Thoracic Surgery Shanghai Pulmonary HospitalTongji University School of MedicineShanghai 200443People’s Republic of China

As one of the most common forms of skin injuries,skin burns are often accompanied by edema pain,suppuration of infection,slow tissue regeneration,and severe scar formation,which significantly delay wound healing as well as affect the quality of *** prepared multifunctional electrospun poly(L-lactide-co-glycolide)/gelatin(P/G)-based dressings to synergistically harness the therapeutic benefits of peppermint essential oil(T),burn ointment(B),and Oregano essential oil(O)(P/G@TBO)for skin regeneration in punch and burn injury *** P/G@TBO can afford the sustained release of bioactive cues for up to 72 h as well as remarkably promote cell migration(ca.P/G@TBO,89%*** group,51%)at 24 *** P/G@TBO membranes also showed significant angiogenic effect as well as antibacterial and anti-inflammatory properties than that of the control group in ***,P/G@TBO dressings enabled fast wound healing(ca.P/G@TBO,100%wound closure *** group,95%)in a full-thickness excisional defect model up to 14 days in *** evaluation of membranes in different animal models,including tail wagging model,facial itch model,and hot burn injury model showed significant pain relieve effect as well as itching and swelling relief functions during earlier stages of wound *** were next transplanted into a scalded wound model in rats and an ear punch wound model in rabbits,which manifested antibacterial and anti-inflammatory properties and promoted re-epithelialization to achieve scarless wound healing percentage wound closure at day 28:P/G@TBO,96%*** group 66%.Taken together our approach of simultaneously harnessing T,B,and O to enable multifunctionality to fibrous dressings may hold great promise for burn wound healing applications and other related disciplines.

关键词： Burn injury Wound healing Skin regeneration Pain and swelling relief Nanofiber membrane

Interaction of tetradecyltrimethylammonium bromide with bovine serum albumin in different compositions: Effect of temperatures and electrolytes/urea

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Chinese Journal of Chemical Engineering 2021年第1期34卷 279-287页

作者： Joynal Abedin ShamimMahbub Mohammad Majibur Rahman Anamul Hoque Dileep Kumar Javed Masood Khan Ahmed M.el-Sherbeeny Department of Chemistry Jahangirnagar UniversitySavarDhaka 1342Bangladesh Department of Chemistry&Physics Gono BishwabidyalaySavarDhaka 1344Bangladesh Department of Environmental Sciences Jahangirnagar UniversitySavarDhaka 1342Bangladesh 4 Division of Computational Phys ics Institute for Computational ScienceTon Duc Thang UniversityHo Chi Minh CityViet Nam Faculty of Applied Sciences Ton Duc Thang UniversityHo Chi Minh CityViet Nam Department of Food Science and Nutrition Faculty of Food and Agricultural SciencesKing Saud University2460Riyadh 11451Saudi Arabia Industrial Engineering Department College of EngineeringKing Saud UniversityP.O.Box 800Riyadh 11421Saudi Arabia

Herein,the interaction of a protein,bovine serum albumin(BSA),with tetradecyltrimethylammonium bromide(TTAB,a cationic surfactant),has been investigated using the conductivity measurement technique in pure water and some sodium salts(NaCl,Na_(2) SO_(4),Na_(2) co_(3), and Na_(3) PO_(4)) solutions at temperature range of 295.15-320.15 *** reveal that,in the plot of specific conductivity versus the concentration of TTAB,only a single critical micelle concentration(cmc) was found for the TTAB+BSA mixed system in all solvents media *** addition of BSA in aqueous TTAB solution,the value of cmc undergoes a change from its pure form,which indicates the presence of strong interaction operating between the BSA and TTAB *** aqueous system,the cmc values of the TTAB+BSA mixtures are obtained higher compared to the values found for single TTAB surfactant However,the addition of salt decreases the cmc value of mixed TTAB+BSA *** values of cmc of the BSA+TTAB mixed system at 310.15 K and 1.00 mmol·kg^(-1) ionic strength of salt followed the order:cmc_(Na_(2) co_(3))> Cmcc_(Na_(3) PO_(4))> cmcNaCl>cMC_(Na_(2) SO_(4)).The cmc values of TTAB+BSA mixture were found to be lowered in urea solution within the concentrations *** values of degree of dissociation(α) and fraction of counter ion binding(β) were found to be dependent on additives and *** free energy of micellization(AGm) is negative for all the systems,which manifests that the micellization phenomenon is energetically *** enhancement of the negative value of △G_(m)^(0) in aqueous salt solutions reveals an increase of spontaneity of the TTAB+BSA micellization *** values of △G_(m)^(0) also reveal that the spontaneity of micelle formation is enhanced at higher temperatures in all media *** values of free energy of transfer(△G_(m,t)^(o)) were also determined for numerous solvent media used in the present study and described with appropriate reasoning.

关键词： TTAB BSA conductivity electrolyte Exothermic interaction

Integrative analysis of the metabolome and transcriptome reveals seed germination mechanism in Punica granatum L.

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Journal of Integrative Agriculture 2021年第1期20卷 132-146页

作者： FU Fang-fang PENG Ying-shu WANG Gui-bin Yousry A.el-KASSABY CAO Fu-liang co-Innovation Center for Sustainable Forestry in Southern China Nanjing Forestry UniversityNanjing 210037P.R.China Department of Forest and conservation Sciences Faculty of ForestryThe University of British ColumbiaVancouverB.C.V6T 1Z4Canada

We conducted an integrative system biology of metabolome and transcriptome profile analyses during pomegranate(Punica granatum L.) seed germination and utilized a weighted gene co-expression network analysis(WGCNA) to describe the functionality and complexity of the physiological and morphogenetic processes as well as gene expression and metabolic differences during seed germination stages. In total, 489 metabolites were detected, including 40 differentially accumulated metabolites. The transcriptomic analysis showed the expression of 6 984 genes changed significantly throughout the whole germination process. Using WGCNA, we identified modules related to the various seed germination stages and hub genes. In the initial imbibition stage(stage 1), the pivotal genes involved in RNA transduction and the glycolytic pathway were most active, while in the sprouting stage(stage 4), the pivotal genes were involved in multiple metabolic pathways. In terms of secondary metabolic pathways, we found flavonoid 4-reductase genes of anthocyanin biosynthesis pathway are most significantly affected during pomegranate seed germination, while the flavonol synthase gene was mainly involved in the regulation of isoflavonoid biosynthesis.

关键词： seed germination stages weighted gene co-expression network analysis(WGCNA) metabolome transcriptome flavonoid pathway

Energy and cost Analysis of Processing Flat Plate Solar collectors

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Energy Engineering 2021年第3期118卷 447-458页

作者： Mamdouh el Haj Assad Ali Khosravi Mohammad AlShabi Bassam Khuwaileh Abdul-Kadir Hamid Sustainable and Renewable Energy Engineering Department University of SharjahSharjahUnited Arab Emirates Mechanical Engineering Department Aalto UniversityEspooFinland Mechanical and Nuclear Energy Engineering Department University of SharjahSharjahUnited Arab Emirates electrical Engineering Department University of SharjahSharjahUnited Arab Emirates

In this work,a life cycle analysis is accomplished for flat plate solar *** purpose of this investigation is to predict the energy consumption during the manufacturing processes that results in carbon dioxide *** consumption and system efficiency enhancement will be studied and *** EduPack software is used to perform the analysis of the currently commercial system,and the suggested changes are implemented to increase the efficiency and make the *** though cost analysis is done,the priority of selection is given to the most energy conserving and environmentally friendly ***,if the compared alternatives result in the same energy consumption and co_(2)emissions,the cost analysis would be a better *** can be stated that flat plate solar collectors are sustainable and renewable energy systems that do not produce co_(2)emissions during their active usage,but the manufacturing processes they undergo during the design contribute to the greenhouse gasses emission.

关键词： Life cycle solar collector renewable energy solar thermal co_(2)emission economic analysis

Tuberculosis/toxoplasmosis co-infection in Egyptian patients:A reciprocal impact

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Asian Pacific Journal of Tropical Medicine 2017年第3期10卷 295-299页

作者： Mervat Mashaly Nairmen Nabih Iman M.Fawzy Abeer A.el Henawy Department of Clinical Pathology Microbiology UnitFaculty of MedicineMansoura University Department of Medical Parasitology Faculty of MedicineMansoura University Department of Laboratory Medicine Mansoura Fever HospitalMinistry of Health 不详

Objective:To assess the concurrent toxoplasmosis infection in Egyptian TB patients and the impact of each infection on the other in terms of increased severity of TB or reactivation of latent Toxoplasma ***:Three hundred suspected pulmonary TB cases were initially screened for TB using direct Ziehl Neelsen staining and Lowenstein Jensen culture of their *** resistance was detected by Xpert MTB/RIF *** group of 30 age and sex-matched healthy individuals negative for TB was included for *** subjects were further assessed for serum levels of anti-Toxoplasma Ig G antibodies and malondialdehyde(MDA).Results:Forty three confirmed TB-infected patients including 10(23.3%)rifampicin-resistant patients were *** toxoplasmosis was found to be significantly higher among TB patients(OR=2.709;95%CI:1.034-7.099;Pels of anti-Toxoplasma IgG antibodies and MDA were significantly higher among TB patients than the control ***,serum level of MDA was significantly higher among TB/Toxoplasma co-infected patients as compared to toxoplasmosis free-TB *** positive correlation was detected between serum levels of anti-Toxoplasma Ig G and MDA in TB patients(r=0.75,P=0.001).conclusions:Among pulmonary TB Egyptian patients,there is a considerable prevalence of *** of pulmonary tuberculosis could be increased by Toxoplasma co-infection.

关键词： co-infection MDA Oxidative stress Toxoplasmosis Tuberculosis

A coupled catalyst composed of coFe_(2)O_(4) magnetic nanoparticle and[HMIM]Br-FeCl_(3) to intensify the oxidative desulfurization of FCC diesel

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Green Chemical Engineering 2021年第4期2卷 441-449页

作者： Yanlin Zhang Xinyu Zhang Guangren Yu Xiaochun Chen Ahmed A.Abdeltawab Hany el-Hamshary Beijing Key Laboratory of Membrane Science and Technology&college of Chemical Engineering Beijing University of Chemical TechnologyBeijing100029China Department of Chemistry College of ScienceKing Saud UniversityRiyadh11451Saudi Arabia

Ionic liquids have been extensively studied as solvents or catalysts for oxidative desulfurization(ODS)of diesel fuel,but it is still a challenge to reduce the desulfurization time and *** this work,a new highly efficient desulfurization system composed of coFe_(2)O_(4) magnetic nanoparticle,[HMIM]Br-FeCl_(3) and H_(2)O_(2) was developed for the ODS of FCC diesel *** desulfurization performances were investigated including desulfurization time,temperature,volume ratio of IL/oil,O/S molar ratio,dosage of coFe_(2)O_(4),FeCl_(3) content in ILs,regeneration,and reuse of catalyst and *** to the coupled catalytic roles of coFe_(2)O_(4) magnetic nanoparticle and[HMIM]Br-FeCl_(3),where co2t and Fe3t interact with H_(2)O_(2) to produce ·OH radical that converts S-compounds into sulfone and sulfoxide compounds,such a desulfurization system is highly effective in removing S-compound in diesel *** S-content in FCC diesel fuel was reduced from the original 272.8 ppm to 0.5 ppm with 99.82%S-removal efficiency after one step within 8 minunder the optimal conditions of 25℃,8 min,V(IL/oil)=1:10,O/S=20,5 wt%coFe_(2)O_(4) dosage and n([HMIM]Br)/n(FeCl_(3))=1:1;the desulfurization performance is much better in desulfurization time and steps than other desulfurization systems reported *** desulfurization system can be regenerated and reused without remarkable loss of desulfurization activity.A desulfurization mechanism was proposed.

关键词： coFe_(2)O_(4)magnetic nanoparticle Ferric chloride ionic liquids Oxidative desulfurization