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10B-doped MCP detector developed for neutron resonance imaging at Back-n white neutron source

Nuclear Science and Techniques 2024年第8期35卷 58-68页

作者： Qiang li li‑Jiao Wang Jing‑Yu Tang xiang‑Biao Qiu Zhen Chen Mao‑Yuan Zhao chang‑Jun Ning Kai Pan Wei xu Tao li Su‑Peng Lu Han Yi Rui‑Rui Fan chang‑Qing feng Rong Zhang Xiao‑Yang Sun Qi An Hao‑Fan Bai jiang‑Bo Bai Jie Bao Ping Cao Qi‑Ping Chen Yong‑Hao Chen Zeng‑Qi Cui An‑Chuan Fan Fan‑Zhen feng Min‑Hao Gu chang‑Cai Han Zi‑Jie Han guo‑Zhu He Yong‑Cheng He Yang Hong Yi‑Wei Hu Han‑Xiong Huang Wei jiang Zhi‑Jie jiang Zheng‑Yao Jin ling Kang Bo li Gong li Xiao li Yang li Jie liu Rong liu Shu‑Bin liu Yi‑Na liu Guang‑Yuan Luan Jie Ren Zhi‑Zhou Ren Xi‑Chao Ruan Zhao‑Hui Song Kang Sun Zhi‑Xin Tan sheng‑Da Tang Jin‑Cheng Wang Peng‑Cheng Wang Zhao‑Hui Wang zhong‑Wei Wen Xiao‑Guang Wu xuan Wu Cong Xia Yong‑Ji Yu guo‑Hui Zhang Hang‑chang Zhang lin‑Hao Zhang Qi‑Wei Zhang Xian‑Peng Zhang Yu‑liang Zhang Yue Zhang Zhi‑Yong Zhang Zhi‑Hao Zhou Ke‑Jun Zhu Chong Zou Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China State Key Laboratory of Particle Detection and Electronics Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Dongguan Songshan Lake Future School Dongguan 523808China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230027China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China North Night Vision Science and Technology(Nanjing)Research Institute Co.Ltd Nanjing 211106China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Institute of Modern Physics Fudan UniversityShanghai 200433China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China China Academy of Engineering Physics Institute of Nuclear Physics and ChemistryMianyang 621900China USTC archaeometry lab University of Science and Technology of ChinaHefei 230026China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China China Shipbuilding Trading Co. LtdBeijing 100044China

Neutron resonance imaging(NRI)has recently emerged as an appealing technique for neutron *** complexity surpasses that of conventional transmission imaging,as it requires a high demand for both a neutron source and ***,the progression of NRI technology has been sluggish since its inception in the 1980s,particularly considering the limited studies analyzing the neutron energy range above *** white neutron source(Back-n)at the China Spallation Neutron Source(CSNS)provides favorable beam conditions for the development of the NRI technique over a wide neutron energy range from eV to ***-sensitive microchannel plates(MCP)have emerged as a cutting-edge tool in the field of neutron detection owing to their high temporal and spatial resolutions,high detection efficiency,and low *** this study,we report the development of a 10B-doped MCP detector,along with its associated electronics,data processing system,and NRI experiments at the *** heavy elements such as gold,silver,tungsten,and indium can be easily identified in the transmission images by their characteristic resonance peaks in the 1–100 eV energy range;the more difficult medium-weight elements such as iron,copper,and aluminum with resonance peaks in the 1–100 keV energy range can also be *** particular,results in the neutron energy range of dozens of keV(Aluminum)are reported here for the first time.

关键词： Neutron resonance imaging 10B doped MCP detector White neutron source Sample nuclide identification

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Shape Setup System for 1700 Hot Strip Mill

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Journal of Iron and Steel Research International 2007年第5期14卷 27-30页

作者： guo zhong-{2. xu jian-zhong li chang-sheng liu xiang-hua State Key Laboratory of Rolling and Automation Northeastern University Shenyang 110004 Liaoning China

Shape setup （SSU） system is the core technology for hot strip mill （HSM）. A precise SSU system was used to improve the strip quality for HSM. The function of SSU, setup, and feedback was introduced. The main mathematical models of roll gap profile and longitudinal strain difference are set up. Strip profile allocation strategy was researched according to the SSU system of a domestic 1 700 mm HSM. The SSU system was put into practical use and the measurement results showed that strip flatness variation and strip profile variation could be controlled in target scope.

关键词： SSU hot strip mill, shape strip profile flatness

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In-beam gamma rays of CSNS Back-n characterized by black resonance filter

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NUCLEAR SCIENCE AND TECHNIQUES 2024年第10期35卷 1-12页

作者： Wang, Jin-Cheng Ren, Jie jiang, Wei Ruan, Xi-Chao liu, Ying-Yi Yang, Hao-Lan xu, Kuo-Zhi Pan, Xin-Yi Sun, Qi Bao, Jie Huang, Han-Xiong Bai, Hao-Fan Bai, jiang-Bo Cao, Ping Chen, Qi-Ping Chen, Yong-Hao Duan, Wen-Hao Fan, An-Chuan Fan, Rui-Rui feng, chang-Qing Gu, Min-Hao Han, chang-Cai Han, Zi-Jie He, guo-Zhu He, Yong-Cheng Hong, Yang Hu, Yi-Wei jiang, Zhi-Jie Kang, ling Lan, chang-lin li, Bo li, feng li, Qiang li, Xiao li, Yang liu, Jie liu, Rong liu, Shu-Bin liu, Yi-Na Luan, Guang-Yuan Ning, chang-Jun Qiu, Yi-Jia Ren, Wen-Kai Ren, Zhi-Zhou Song, Zhao-Hui Sun, Kang Tan, Zhi-Xin Tang, Jing-Yu Tang, sheng-Da Wang, li-Jiao Wang, Peng-Cheng Wang, Zhao-Hui Wen, zhong-Wei Wu, Xiao-Guang Wu, xuan Wu, Ze-Peng Xia, Cong Xie, li-Kun Yi, Han Yu, Tao Yu, Yong-Ji Zhang, guo-Hui Zhang, Hang-chang Zhang, Qi-Wei Zhang, Xian-Peng Zhang, Yu-liang Zhang, Zhi-Yong Zhao, Mao-Yuan Zhou, Zhi-Hao Zhu, Ke-Jun Zou, Chong China Inst Atom Energy Key Lab Nucl Data Beijing 102413 Peoples R China Chinese Acad Sci Inst High Energy Phys Beijing 100049 Peoples R China Spallat Neutron Source Sci Ctr Dongguan 523803 Peoples R China Chinese Acad Sci Inst High Energy Phys State Key Lab Particle Detect & Elect Beijing 100049 Peoples R China Univ Chinese Acad Sci Beijing 100049 Peoples R China Peking Univ Sch Phys State Key Lab Nucl Phys & Technol Beijing 100871 Peoples R China Fudan Univ Inst Modern Phys Shanghai 200433 Peoples R China Univ Sci & Technol China State Key Lab Particle Detect & Elect Hefei 230026 Peoples R China Univ Sci & Technol China Sch Nucl Sci & Technol Hefei 230026 Peoples R China Univ Sci & Technol China Dept Modern Phys Hefei 230026 Peoples R China China Acad Engn Phys Inst Nucl Phys & Chem Mianyang 621900 Peoples R China Univ Sci & Technol China USTC Archaeometry Lab Hefei 230026 Peoples R China Northwest Inst Nucl Technol Xian 710024 Peoples R China Lanzhou Univ Sch Nucl Sci & Technol Lanzhou 730000 Peoples R China Univ Sci & Technol China Inst Adv Technol Hefei 230027 Peoples R China

The back-streaming white-neutron beamline (Back-n) of the China Spallation Neutron Source is an essential neutron- research platform built for the study of nuclear data, neutron physics, and neutron applications. Many types of cross-sectional neutron-reaction measurements have been performed at Back-n since early 2.18. These measurements have shown that a significant number of gamma rays can be transmitted to the experimental stations of Back-n along with the neutron beam. These gamma rays, commonly referred to as in-beam gamma rays, can induce a non-negligible experimental background in neutron-reaction measurements. Studying the characteristics of in-beam gamma rays is important for understanding the experimental background. However, measuring in-beam gamma rays is challenging because most gamma-ray detectors are sensitive to neutrons; thus, discriminating between neutron-induced signals and those from in-beam gamma rays is difficult. In this study, we propose the use of the black resonance filter method and a CeBr3 scintillation detector to measure the characteristics of the in-beam gamma rays of Back-n. Four types of black resonance filters, Ta-181, Co-59, Ag-nat, and Cd-nat, were used in this measurement. The time-of-flight (TOF) technique was used to select the detector signals remaining in the absorption region of the TOF spectra, which were mainly induced by in-beam gamma rays. The energy distribution and flux of the in-beam gamma rays of Back-n were determined by analyzing the deposited energy spectra of the CeBr3 scintillation detector and using Monte Carlo simulations. Based on the results of this study, the background contributions from in-beam gamma rays in neutron-reaction measurements at Back-n can be reasonably evaluated, which is beneficial for enhancing both the experimental methodology and data analysis.

关键词： In-beam gamma rays Back-n Black filter resonance technique In-beam gamma rays Back-n CeBr3 scintillator Black filter resonance technique C6D6 DETECTOR SYSTEM liNE

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Analysis of Temperature Field and Thermal Crown of Roll During Hot Rolling by Simplified FEM

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Journal of Iron and Steel Research International 2006年第6期13卷 27-30,48页

作者： guo zhong-{2. li chang-sheng xu jian-zhong liu xiang-hua WANG guo-dong State Key Laboratory of Rolling and Automation Northeastern University Shenyang 110004 Liaoning China

Thermal crown of roll is an important factor, which affects strip profile. It is necessary to analyze the temperature field and thermal crown of roll for hot strip mill. A new simplified finite element method （FEM） was used to analyze the temperature field and thermal crown of roll, and corresponding models were built according to the practical boundary conditions. Transient roll temperature field and thermal crown were simulated by ANSYS FEM software with considering transient thermal contact and complex boundary condition. Temperature and thermal crown variations on roll surface nodes were obtained. The thermal crown results of roll obtained by FEM simulation were in good agreement with the measured data, indicating that simplified FEM models and results were correct.

关键词： temperature field thermal crown FEM roll

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Study of the response of 10B-doped MCP to wide-energy range neutrons from eV to MeV

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Nuclear Science and Techniques 2024年第8期35卷 132-141页

作者： Qiang li li‑Jiao Wang xiang‑Biao Qiu Jing‑Wen li Wei xu Tao li Ze‑Bin lin chang‑Jun Ning Yong‑Hao Chen Rui‑Rui Fan Kang Sun Jing‑Yu Tang Rong Zhang Han‑Tao Jing Bo Mei Qi An Hao‑Fan Bai jiang‑Bo Bai Jie Bao Ping Cao Qi‑Ping Chen Zhen Chen Zeng‑Qi Cui An‑Chuan Fan chang‑Qing feng Fan‑Zhen feng Ke‑Qing Gao Min‑Hao Gu chang‑Cai Han Zi‑Jie Han guo‑Zhu He Yong‑Cheng He Yang Hong Yi‑Wei Hu Han‑Xiong Huang Wei‑Hua Jia Hao‑Yu jiang Wei jiang Zhi‑Jie jiang Zheng‑Yao Jin ling Kang Bo li Chao li Gong li Jia‑Wen li Xiao li Yang li Jie liu Rong liu Shu‑Bin liu Guang‑Yuan Luan Bin‑Bin Qi Jie Ren Zhi‑Zhou Ren Xi‑Chao Ruan Zhao‑Hui Song Zhi‑Xin Tan sheng‑Da Tang Peng‑Cheng Wang Zhao‑Hui Wang zhong‑Wei Wen Xiao‑Guang Wu xuan Wu li‑Kun Xie Yi‑Wei Yang Han Yi Yong‑Ji Yu guo‑Hui Zhang lin‑Hao Zhang Mo‑Han Zhang Qi‑Wei Zhang Xian‑Peng Zhang Yu‑liang Zhang Yue Zhang Zhi‑Yong Zhang Mao‑Yuan Zhao Lu‑Ping Zhou Zhi‑Hao Zhou Ke‑Jun Zhu Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Dongguan Songshan Lake Future School Dongguan 523808China North Night Vision Science&Technology(Nanjing)Research Institute Co.Ltd. Nanjing 211106China Sino‑French Institute of Nuclear Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230027China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621900China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China USTC Archaeometry Lab University of Science and Technology of ChinaHefei 230026China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China

Neutron-sensitive microchannel plates(nMCPs)have applications in neutron detection,including energy spectrum measurements,neutron-induced cross sections,and neutron imaging.10B-doped MCPs(B-MCPs)have attracted significant attention owing to their potential for exhibiting a high neutron detection efficiency over a large neutron energy *** spatial and temporal resolutions are useful for neutron energy-resolved ***,their practical applications still face many technical *** this study,a B-MCP with 10 mol%10B was tested for its response to wide-energy neutrons from eV to MeV at the Back-n white neutron source at the China Spallation Neutron *** neutron detection efficiency was calibrated at 1 eV,which is approximately 300 times that of an ordinary MCP and indicates the success of 10 B *** factors that caused the reduction in the detection efficiency were simulated and *** neutron energy spectrum obtained using B-MCP was compared with that obtained by other measurement methods,and showed very good consistency for neutron energies below tens of *** response is more complicated at higher neutron energy,at which point the elastic and nonelastic reactions of all nuclides of B-MCP gradually become *** is beneficial for the detection of neutrons,as it compensates for the detection efficiency of B-MCP for high-energy neutrons.

关键词： Neutron radiation image 10B-doped MCP Neutron response Wide-energy range neutrons

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Searching for^(76)Ge neutrinoless double beta decay with the CDEX-1B experiment

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Chinese Physics C 2024年第10期48卷 11-22页

作者： Bing-Tao Zhang Jun-Zheng Wang li-Tao Yang Qian Yue Ke-Jun Kang Yuan-Jing li Hai-Peng An C.Greeshma jian-Ping chang Yun-Huan Chen jian-Ping Cheng Wen-Han Dai Zhi Deng chang-Hao Fang Xin-Ping Geng Hui Gong Qiu-Ju guo xu-Yuan guo li He sheng-Ming He Jin-Wei Hu Han-Xiong Huang Tu-Chen Huang Hai-Tao Jia Xi jiang S.Karmakar Hao-Bin li jian-Min li Jin li Qian-Yun li Ren-Ming-Jie li xue-Qian li Yu-Lan li Yi-Fan liang Bin liao Fong-Kay lin Shin-Ted lin Jia-xuan liu Shu-Kui liu Yan-Dong liu Yu liu Yuan-Yuan liu zhong-Zhi liu Hao Ma Yu-Cai Mao Qi-Yuan Nie Jin-Hua Ning Hui Pan Ning-Chun Qi Jie Ren Xi-Chao Ruan Ze She Manoj Kumar Singh Tian-Xi Sun chang-jian Tang Wei-You Tang Yang Tian Guang-Fu Wang li Wang Qing Wang Yu-feng Wang Yun-xiang Wang Henry-Tsz-King Wong Shi-Yong Wu Yu-Cheng Wu Hao-Yang Xing Rui xu Yin xu Tao xue Yu-Lu Yan Nan Yi Chun-xu Yu Hai-Jun Yu jian-feng Yue Ming Zeng Zhi Zeng feng-Shou Zhang Lei Zhang Zhen-Hua Zhang Zhen-Yu Zhang Kang-Kang Zhao Ming-Gang Zhao Ji-Fang Zhou Zu-Ying Zhou Jing-Jun Zhou Key Laboratory of Particle and Radiation Imaging(Ministry of Education)and Department of Engineering Physics Tsinghua UniversityBeijing 100084 Department of Physics Tsinghua UniversityBeijing 100084 Institute of Physics Academia SinicaTaipei 11529 NUCTECH Company Beijing 100084 YaLong River Hydropower Development Company Chengdu 610051 College of Nuclear Science and Technology Beijing Normal UniversityBeijing 100875 College of Physics Sichuan UniversityChengdu 610065 School of Physics Peking UniversityBeijing 100871 Department of Nuclear Physics China Institute of Atomic EnergyBeijing 102413 Sino-French Institute of Nuclear and Technology Sun Yat-sen UniversityZhuhai 519082 School of Physics Nankai UniversityTianjin 300071 Department of Physics Banaras Hindu UniversityVaranasi 221005 Department of Physics Beijing Normal UniversityBeijing 100875

We operated a p-type point contact high purity germanium(PPCGe)detector(CDEX-1B,1.008 kg)in the China Jinping Underground Laboratory(CJPL)for 500.3 days to search for neutrinoless double beta(0νββ)decay of^(76)Ge.A total of 504.3 kg⋅day effective exposure data was *** anti-coincidence and the multi/single-site event(MSE/SSE)discrimination methods were used to suppress the background in the energy region of interest(ROI,1989–2.89 keV for this work)with a factor of 2..A background level of 0.33 counts/(keV⋅kg⋅yr)was *** lower limit on the half life of^(76)Ge 0νββdecay was constrained as T_(1/2.^(0ν)>1.0×10^(2.)yr(90%C.L.),corresponding to the upper limits on the effective Majorana neutrino mass:2.7.5 eV.

关键词： neutrinoless double beta decay CDEX point-contact germanium detector ^(76)Ge

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The In-Flight Realtime Trigger and Localization Software of GECAM

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Research in Astronomy and Astrophysics 2024年第10期24卷 11-24页

作者： Xiao-Yun Zhao Shao-lin Xiong xiang-Yang Wen Xin-Qiao li Ce Cai Shuo Xiao Qi Luo Wen-Xi Peng Dong-Ya guo Zheng-Hua An Ke Gong Jin-Yuan liao Yan-Qiu Zhang Yue Huang Lu li Xing Wen Fei Zhang Jing Duan Chen-Wei Wang Dong-li Shi Peng Zhang Qi-Bin Yi Chao-Yang li Yan-Bing xu Xiao-Hua liang Ya-Qing liu Da-li Zhang Xi-Lei Sun Fan Zhang Gang Chen Huan-Yu Wang sheng Yang Xiao-Jing liu Min Gao Mao-Shun li Jin-Zhou Wang Xing Zhou Yi Zhao Wang-Chen xue Chao Zheng Jia-Cong liu Xing-Bo Han Jin-ling Qi Jia Huang Ke-Ke Zhang Can Chen Xiong-Tao Yang Dong-Jie Hou Yu-Sa Wang Rui Qiao xiang Ma Xiao-Bo li Ping Wang Xin-Ying Song li-Ming Song Shi-Jie Zheng Bing li Hong-Mei Zhang Yue Zhu Wei Chen jian-jian He Zhen Zhang Jin Hou Hong-Jun Wang Yan-Chao Hao xiang-Yu Wang Zong-Yuan Yang Zhi-Long Wen Zhi chang Yuan-Yuan Du Rui Gao Xiao-Fei Lan Yan-guo li Gang li xu-Fang li Fang-Jun Lu Hong Lu Bin Meng feng Shi Hui Wang Hui-Zhen Wang Yu-Peng xu Jia-Wei Yang xue-Juan Yang Shuang-Nan Zhang Chao-Yue Zhang Cheng-Mo Zhang Zhi-Cheng Tang Cheng Cheng Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China School of Information Science and Technology Southwest Jiaotong UniversityChengdu 611756China Key Laboratory of Stellar and Interstellar Physics and Department of Physics Xiangtan UniversityXiangtan 411105China Physics and Space Science College China West Normal UniversityNanchong 637002China Department of Astronomy Beijing Normal UniversityBeijing 100875China Innovation Academy for Microsatellites of CAS Shanghai 201203China changchun University of Science and Technology Changchun 130022China Chinese Academy of Sciences South America Center for Astronomy National Astronomical ObservatoriesCASBeijing 100101China

Realtime trigger and localization of bursts are the key functions of GECAM,an all-sky gamma-ray monitor launched on 2.2. December *** developed a multifunctional trigger and localization software operating in the CPU of the GECAM Electronic *** onboard software has the following features:high trigger efficiency for real celestial bursts with a suppression of false triggers caused by charged particle bursts and background fluctuation,dedicated localization algorithm optimized for both short and long bursts,and low time latency of the trigger information which is downlinked through the Global Short Message Communication service of the global BeiDou navigation *** paper provides a detailed description of the design and development of the trigger and localization software system for *** covers the general design,workflow,the main functions,and the algorithms used in the *** paper also includes on-ground trigger tests using simulated gamma-ray bursts generated by a dedicated X-ray tube,as well as an overview of the performance for real celestial bursts during its in-orbit operation.

关键词： telescopes instrumentation:detectors methods:observational

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Incidence and prognosis of olfactory and gustatory dysfunctions related to SARS-CoV-2.Omicron strain infection in China:A national multicenter survey of 35,566 individuals

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第2期10卷 113-120页

作者： Meng-Fan liu Rui-Xia Ma Xian-Bao Cao Hua Zhang Shui-Hong Zhou Wei-Hong jiang Yan jiang Jing-Wu Sun Qin-Tai Yang xue-zhong li Ya-Nan Sun li Shi Min Wang Xi-Cheng Song Fu-Quan Chen Xiao-Shu Zhang Hong-Quan Wei Shao-Qing Yu Dong-Dong Zhu Luo Ba Zhi-Wei Cao xu-Ping Xiao Xin Wei Zhi-Hong lin feng-Hong Chen Chun-Guang Shan Guang-Ke Wang Jing Ye Shen-Hong Qu chang-Qing Zhao Zhen-lin Wang Hua-Bin li feng liu Xiao-Bo Cui sheng-Nan Ye Zheng liu Yu xu Xiao Cai Wei Huang Ru-Xin Zhang Yu-lin Zhao guo-Dong Yu Guang-Gang Shi Mei-Ping Lu Yang Shen Yu-Tong Zhao Jia-Hong Pei Shao-Bing Xie Long-Gang Yu Ye-Hai liu Shao-Wei Gu Yu-Cheng Yang Lei Cheng jian-feng liu Graduate School of Beijing University of Chinese Medicine BeijingChina Department of Otorhinolaryngology Head and Neck Surgery China-Japan Friendship HospitalBeijingChina Department of Otorhinolaryngology Head and Neck Surgery The First People's Hospital of YinchuanYinchuanChina Department of Otorhinolaryngology The First People's Hospital of Yunnan ProvinceKunmingChina Department of Otorhinolaryngology The First Affiliated Hospital of Xinjiang Medical UniversityUrumqiChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of Zhejiang University School of MedicineHangzhouChina Department of Otorhinolaryngology Head and Neck Surgery Xiangya Hospital Central South UniversityChangshaChina Department of Otorhinolaryngology Head and Neck Surgery The Affiliated Hospital of Qingdao UniversityQingdaoChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of USTCHefeiChina Department of Otorhinolaryngology Head and Neck Surgery The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouChina Department of Otorhinolaryngology Head and Neck Surgery Qilu Hospital of Shandong UniversityJinanChina Department of Otorhinolaryngology Head and Neck Surgery The Second Affiliated Hospital of Harbin Medical UniversityHarbinChina Department of Otolaryngology The Second Hospital of Shandong UniversityShandong UniversityJinanChina Department of Otorhinolaryngology Head and Neck Surgery Peking University People's HospitalBeijingChina Department of Otorhinolaryngology Head and Neck Surgery Yantai Yuhuangding HospitalQingdao UniversityYantaiChina Department of Otorhinolaryngology Head and Neck Surgery Xijing HospitalThe Fourth Military Medical UniversityXi'anChina Gansu Provincial Center for Disease Control and Prevention LanzhouChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of China Medical UniversityShenyangChina Department of Otorhinolaryngology Head and Neck Surgery Tongji Hospit

Objective:This cross-sectional study aimed to determine the epidemiology of olfactory and gustatory dysfunctions related to COVID-19 in ***:This study was conducted by 45 tertiary Grade-A hospitals in *** and offline questionnaire data were obtained from patients infected with COVID-19 between December 2.,2.2.,and February 2.,*** collected information included basic demographics,medical history,smoking and drinking history,vaccination history,changes in olfactory and gustatory functions before and after infection,and other postinfection symptoms,as well as the duration and improvement status of olfactory and gustatory ***:Complete questionnaires were obtained from 35,566 *** overall incidence of olfactory and taste dysfunction was 67.75%.Being female or being a cigarette smoker increased the likelihood of developing olfactory and taste *** received four doses of the vaccine or having good oral health or being a alcohol drinker decreased the risk of such *** infection,the average olfactory and taste VAS scores were 8.41 and 8.51,respectively;after infection,they decreased to 3.69 and 4.2. and recovered to 5.83 and 6.55 by the time of the *** median duration of dysosmia and dysgeusia was 15 and 12.days,respectively,with 0.5%of patients having symptoms lasting for more than 2. *** overall self-reported improvement rate was 59.16%.Recovery was higher in males,never smokers,those who received two or three vaccine doses,and those that had never experienced dental health issues,or chronic accompanying ***:The incidence of dysosmia and dysgeusia following infection with the SARS-CoV-2.virus is high in *** and prognosis are influenced by several factors,including sex,SARS-CoV-2.vaccination,history of head-facial trauma,nasal and oral health status,smoking and drinking history,and the persistence of accompanying symptoms.

关键词： epidemiologic studies incidence olfactory disorders prognosis SARS-CoV-2 taste disorders

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Effect of stabilizing treatment on microstructure and stress rupture properties of phosphorus microalloyed Inconel 706 alloy

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Journal of Iron and Steel Research International 2023年第8期30卷 1613-1621页

作者： Sha Zhang Yu-chao Wu Yu lil zhong-pei Dail Dan Jia Yan-fei {2. Guang-sheng Zeng Zhi-ming guo jian liul College of Mechanical&Electrical Engineering Changsha UniversityChangsha 410022HunanChina Hunan Engineering Research Center of Research and Development of Degradable Materials and Molding Technology Changsha UniversityChangsha 410022HunanChina changsha Kaiple Technology Co. Ltd.Changsha 410114HunanChina Institute of Metal Research Chinese Academy of SciencesShenyang 110016LiaoningChina

The microstructure and stress rupture properties of Inconel 706 alloy microalloyed with phosphorus are examined under stabilizing and unstabilizing heat treatment *** was found that applying the stabilizing treatment resulted in a 98% increment in the stress rupture life and a 2.5% increment in the elongation tested at 650℃/690 MPa for the alloy compared to that under the unstabilizing heat treatment *** stabilizing treatment led to the precipitation of rod-shaped and needle-shaped n phases at the grain *** of γ'-γ" co-precipitates in the grain interior were noncompact form and compact form for the alloy under unstabilizing and stabilizing heat treatment conditions,*** on the microstructure characterizations,the improvement of stress rupture properties by the stabilizing treatment was attributed to the precipitation of n phases at the grain boundaries,which can hinder cracks initiation and propagation and relieve the stress concentration.

关键词： Superalloy Stabilization ηphase γ'-γ"co-precipitate Stress rupture property

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Basonuclin 1 deficiency causes testicular premature aging: BNC1 cooperates with TAF7L to regulate spermatogenesis

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Journal of Molecular Cell Biology 2020年第1期12卷 71-83页

作者： Jing-Yi li Yi-feng {2. Hai-Yan xu Jun-Yu Zhang Ping-Ping Lv Miao-E {2. Yan-Yun Ying Ye-Qing Qian Kun li Cheng li Yun Huang Gu-feng xu guo-lian Ding Yu-Chan Mao Chen-Ming xu Xin-Mei {2. jian-zhong sheng Dan Zhang He-feng Huang Key Laboratory of Reproductive Genetics(Ministry of Education)and Department of Reproductive Endocrinology Women's HospitalZhejiang University School of MedicineHangzhou 310006China International Peace Maternal and Child Health Hospital Shanghai Jiao Tong UniversityShanghai 200030China Department of Pathology&Pathophysiology Zhejiang University School of MedicineHangzhou 310000China

Basonuclin(BNC1)is expressed primarily in proliferative keratinocytes and gametogenic ***,its roles in spermatogenesis and testicular aging were not *** we discovered a heterozygous BNC1 truncation mutation in a premature ovarian insufficiency *** this study,we found that male mice carrying the truncation mutation exhibited progressively fertility loss and testicular premature ***-wide expression profiling and direct binding studies(by chromatin immunoprecipitation sequencing)with BNC1 in mouse testis identified several spermatogenesis-specific gene promoters targeted by BNC1 including kelch-like family member 10(Klhl1O),testis expressed 14(Tex14)9 and spermatogenesis and centriole associated 1(Spatcl).Moreover,biochemical analysis showed that BNC1 was associated with TATA-box binding protein-associated factor 7 like(TAF7L),a germ cell-specific paralogue of the transcription factor IID subunit TAF7,both in vitro and in testis,suggesting that BNC1 might directly cooperate with TAF7L to regulate *** truncation mutation disabled nuclear translocation of the BNC1/TAF7L complex,thus,disturbing expression of related genes and leading to testicular premature ***,expressions of Y-box-binding protein 2.YBX2.,outer dense fiber of sperm tails 1(ODfl),and glyceraldehyde-3-phosphate dehydrogenase,spermatogenic(GAPDHS)were significantly decreased in the testis of men with non-obstructive *** present study adds to the understanding of the physiology of male reproductive aging and the mechanism of spermatogenic failure in infertile men.

关键词： testicular aging spermatogenesis BNC1 TAF7L gene mutation

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