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Earthquake Engineering and Engineering Vibration 2024年第1期23卷 209-225页

作者： Wu Xiangtong Yuan Wenting guo Anxin Key Lab of Smart Prevention and Mitigation of Civil Engineering Disasters of the Ministry of Industry and Information Technology Harbin Institute of TechnologyHarbin 150090China Key Lab of Structures Dynamic Behavior and Control of the Ministry of Education Harbin Institute of TechnologyHarbin 150090China Institute of Transportation Inner Mongolia UniversityHohhot 010070China

Reinforcement corrosion is the main cause of performance deterioration of reinforced concrete(RC)*** research has been performed to investigate the life-cycle cost(LCC)of coastal bridge piers with nonuniform corrosion using different *** this study,a reliability-based design optimization(RBDO)procedure is improved for the design of coastal bridge piers using six groups of commonly used materials,i.e.,normal performance concrete(NPC)with black steel(BS)rebar,high strength steel(HSS)rebar,epoxy coated(EC)rebar,and stainless steel(SS)rebar(named NPC-BS,NPC-HSS,NPC-EC,and NPC-SS,respectively),NPC with BS with silane soakage on the pier surface(named NPC-Silane),and high-performance concrete(HPC)with BS rebar(named HPC-BS).First,the RBDO procedure is improved for the design optimization of coastal bridge piers,and a bridge is selected to illustrate the ***,reliability analysis of the pier designed with each group of materials is carried out to obtain the time-dependent reliability in terms of the ultimate and serviceability ***,the repair time of the pier is predicted based on the time-dependent reliability ***,the time-dependent LCCs for the pier are obtained for the selection of the optimal design.

关键词： reliability-based design optimization(RBDO) life-cycle cost(LCC) nonuniform corrosion coastal bridge pier repair

Improved CS Algorithm and its Application in Parking Space Prediction

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Journal of Bionic Engineering 2020年第5期17卷 1075-1083页

作者： Rui guo Xuanjing Shen Hui Kang College of Computer Science and Technology Jilin UniversityChangchun 130012China Key Laboratory of Symbolic Computation and Knowledge Engineering of Ministry of Education Jilin UniversityChangchun 130012China

This paper simulates the cuckoo incubation process and flight path to optimize the Wavelet Neural Network(WNN)model,and proposes a parking prediction algorithm based on WNN and improved Cuckoo Search(CS)***,the initialization parameters are provided to optimize the WNN using the improved *** traditional CS algorithm adopts the strategy of overall update and evaluation,but does not consider its own information,so the convergence speed is very *** proposed algorithm employs the evaluation strategy of group update,which not only retains the advantage of fast convergence of the dimension-by-dimension update evaluation strategy,but also increases the mutual relationship between the nests and reduces the overall running ***,we use the WNN model to predict parking *** proposed algorithm is compared with six different heuristic algorithms in five *** experimental results show that the proposed algorithm is superior to other algorithms in terms of running time and accuracy.

关键词： wavelet neural network cuckoo search algorithm available parking spaces prediction bionic

WELL TESTING ANALYSIS FOR HORIZONTAL WELL WITH CONSIDERATION OF THRESHOLD PRESSURE GRADIENT IN TIGHT GAS RESERVOIRS

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Journal of Hydrodynamics 2012年第4期24卷 561-568页

作者： guo Jing-jing ZHANG Su ZHANG Lie-hui QING Hairuo LIU Qi-guo State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum UniversityChengdu 610500 China Central Sichuan Mining District PetroChina Southwest Oil and Gas Field Company Suining 629000 China Department of Geology University of Regina Regina SK S4S 0A2 Canada

A fundamental solution for homogeneous reservoir in infinite space is derived by using the point source function with the consideration of the threshold pressure gradient. The fundamental solution of the continuous point source function is then derived based on the Green function. Various boundary conditions of the reservoirs are considered for this case and the corresponding solutions are obtained through the mirror image reflection and the principle of superimposition. The line source solution is obtained by integration. Subsequently, the horizontal-well bottom hole pressure response function for a non-linear gas flow in the homogeneous gas reservoir is obtained, and the response curve of the dimensionless bottom hole pressure and the derivative for a horizontal well in the homogeneous gas reservoir are obtained. In the end, the sensitivities of the relevant parameters are analyzed, The well test model presented in this paper can be used as the basis of the horizontal well test analysis for tight gas reservoirs.

关键词： horizontal well non-linear gas flow threshold pressure gradient tight gas reservoir

Infective Artery Rupture of Renal Allografts:A Single-Center Retrospective Study in China

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Current Medical Science 2022年第4期42卷 847-855页

作者： Yu-liang guo Xia LU Lan ZHU Dun-feng DU Bin LIU Zhong-hua Klaus CHEN Song CHEN Wei-jie ZHANG zhi-shui CHEN Sheng CHANG Institute of Organ Transplantation Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyKey Laboratory of Organ TransplantationMinistry of EducationNHC Key Laboratory of Organ TransplantationKey Laboratory of Organ TransplantationChinese Academy of Medical SciencesWuhan 430030China

Objective:This study investigated the composition of pathogenic microorganisms,clinical features,and therapeutic strategies of infective artery rupture of renal allografts in recipients receiving deceased donor(DD)***:We retrospectively studied the clinical data of the DD kidney transplant recipients with donor-associated infection at Tongji Hospital,Wuhan,China from January 1,2015 to December 31,2018,related recipients and corresponding *** collected the entire results of pathogenic microorganisms cultured from these related ruptured kidneys and then analyzed their distribution and ***:A total of 1440 kidney transplants from DD were performed in our *** total incidence of infective artery rupture in kidney transplants was about 0.76%(11/1440),and the annual incidence ranged from 0.25%to 1.03%.The microbial culture results revealed that 11 recipients suffered from infective artery rupture and 3 recipients who accepted the kidney from same donor had the donor-associated pathogens,including 9 fungal strains(28.1%)and 23 bacterial strains(71.9%).There were 4 recipients infected with multi-drug-resistant Staphylococcus and Klebsiella pneumoniae from the above 11 recipients,of which,10 recipients underwent graft loss,and one died of septic *** microbial cultures of the remaining 3 recipients who received appropriate anti-infective regimens turned negative eventually,and the patients were discharged successfully without significant ***:Renal recipients with infections derived from DDs were at high risk of artery rupture,graft loss,or even *** anti-infective treatment is essential to reduce the incidence of artery rupture and mortality.

关键词： kidney transplantation deceased donor renal artery rupture infection

Dynamic characteristics of multi-span spinning beams with elastic constraints under an axial compressive force

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Applied Mathematics and Mechanics(English Edition) 2024年第2期45卷 295-310页

作者： Xiaodong guo Zhu SU Lifeng WANG State Key Laboratory of Mechanics and Control for Aerospace Structures Nanjing University of Aeronautics and AstronauticsNanjing 210016China

A theoretical model for the multi-span spinning beams with elastic constraints under an axial compressive force is *** displacement and bending angle functions are represented through an improved Fourier series,which ensures the continuity of the derivative at the boundary and enhances the *** exact characteristic equations of the multi-span spinning beams with elastic constraints under an axial compressive force are derived by the Lagrange *** efficiency and accuracy of the present method are validated in comparison with the finite element method(FEM)and other *** effects of the boundary spring stiffness,the number of spans,the spinning velocity,and the axial compressive force on the dynamic characteristics of the multi-span spinning beams are *** results show that the present method can freely simulate any boundary constraints without modifying the solution *** elastic range of linear springs is larger than that of torsion springs,and it is not affected by the number of *** an increase in the axial compressive force,the attenuation rate of the natural frequency of a spinning beam with a large number of spans becomes larger,while the attenuation rate with an elastic boundary is lower than that under a classic simply supported boundary.

关键词： multi-span spinning beam elastic constraint improved Fourier series free vibration semi-analytical solution

利用矩阵变换求解电力系统短路故障的残压变换法

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中国电机工程学报 2005年第23期25卷 61-65页

作者：姜彤白雪峰郭志忠吕颖华北电力大学电力系统保护与动态安全监控教育部重点实验室北京市昌平区102206 哈尔滨工业大学电气工程及自动化学院黑龙江省哈尔滨市150001 清华大学电机工程与应用电子技术系北京市海淀区100084

参数不对称元件的出现为对称分量法处理不对称故障的序网联接处理方法设置了障碍。该文针对之以相分量法故障处理方法为依据,建立了相分量坐标下适用于各种短路故障公式化的残压变换法,并以矩阵变换的方式完成不对称短路故障的处理:通... 详细信息

参数不对称元件的出现为对称分量法处理不对称故障的序网联接处理方法设置了障碍。该文针对之以相分量法故障处理方法为依据,建立了相分量坐标下适用于各种短路故障公式化的残压变换法,并以矩阵变换的方式完成不对称短路故障的处理:通过公式变换将该方法应用于对称分量坐标。使用矩阵运算代替对称分量法的传统序网故障变换,以实现不对称短路故障计算,并给出常见故障对应的参数矩阵。对于多重短路故障和含不对称元件的网络都能够直接处理,而计算量却不会明显增大。文中用实例证明了该方法简单实用,而且便于程序实现。

关键词：电力系统短路电流计算对称分量相分量

Lyapunov-Based Output Containment Control of Heterogeneous Multi-Agent Systems With Markovian Switching Topologies and Distributed Delays

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IEEE/CAA Journal of Automatica Sinica 2023年第6期10卷 1421-1433页

作者： Haihua guo Min Meng Gang Feng the Department of Biomedical Engineering City University of Hong KongHong KongChina the Department of Control Science and Engineering College of Electronics and Information Engineeringand Shanghai Research Institute of Intelligent Autonomous SystemsTongji UniversityShanghai 200092China

This paper considers the mean square output containment control problem for heterogeneous multi-agent systems(MASs)with randomly switching topologies and nonuniform distributed *** modeling the switching topologies as a continuous-time Markov process and taking the distributed delays into consideration,a novel distributed containment observer is proposed to estimate the convex hull spanned by the leaders'states.A novel distributed output feedback containment controller is then designed without using the prior knowledge of distributed *** constructing a novel switching Lyapunov functional,the output containment control problem is then solved in the sense of mean square under an easily-verifiable sufficient ***,two numerical examples are given to show the effectiveness of the proposed controller.

关键词： Heterogeneous multi-agent systems Lyapunov method Markovian switching topologies output containment control time delays

A Novel Synthetic Analogue of Curcumin, B7, Inhibits Inflammatory Factors Expression in H_2O_2 Induced Endothelial Cells

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Chinese Journal of Biomedical Engineering(English Edition) 2015年第3期24卷 93-98页

作者： WEI Dang-heng LIU Yang-hui JIA Xiao-ying guo Feng-xia WU Jiang-zhang The Institute of Cardiovascular Disease Key Laboratory for Arteriosclerology of Hunan Province University of South China School of Pharmacy Wenzhou Medical College

Curcum in, a dietary phytochemical, exhibits multifunctional natural product with regulatory effects on inflammation. However, the poor bioavailability limits its clinical applications. Thus, we designed and synthesized a novel monocarbonyl analogue of curcumin B7 and their inhibition against monocyte chemotactic protein-1(MCP-1) and interleukin-8(IL-8) release was evaluated in H_2O_2-stimulated human vascular endothelial cells(ECs) in a dose-responsive manner, while exhibiting no cytotoxicity in ECs. Taken together, these insights on the novel compound B7 may serve as potential agents for the treatment of atherosclerosis.

关键词： curcumin atherosclerosis B7 inflammation interleukin-8

Separation and Identification of Isotopes Produced from ^(20)Ne+Be Reaction by Radioactive Ion Beam Line in Lanzhou

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Chinese Physics Letters 1998年第11期15卷 790-792页

作者： SUN zhi-yu ZHAN Wen-long guo Zhong-yan XIAO guo-qing WANG Jin-chuan LI Jia-xing JIANG Shan-hong MENG Xiang-wei QIN Li-jun WANG Quan-jin Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000

The separation and identification of isotopes emitted from the projectile fragmentation reaction of 80 MeV/u 20Ne on 9Be target were carried out by using the radioactive ion beam line in Lanzhou(RIBLL).Many proton rich isotopes are *** intensity and purity fit the theoretical *** separation and identification abilities of RIBLL A/ΔA>300 and Q/ΔQ>150,are obtained.

关键词： MeV/u separation purity

基于SIRT1/NF-κB信号通路探究丹参酮ⅡA对抗结核药物致小鼠肝损伤的影响

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中成药 2022年第10期44卷 3151-3156页

作者：王芝林于国英青海省第四人民医院临床药学室青海西宁810000 青海省第四人民医院肝病科青海西宁810000

目的探讨丹参酮ⅡA对抗结核药物致小鼠肝损伤及沉默信息调节因子1(SIRT1)/核因子-κB(NF-κB)信号通路的影响。方法将60只小鼠随机分为对照组,模型组,丹参酮ⅡA低、高剂量组,SRT1720(SIRT1激活剂)组,丹参酮ⅡA+EX527(SIRT1抑制剂)组,... 详细信息

目的探讨丹参酮ⅡA对抗结核药物致小鼠肝损伤及沉默信息调节因子1(SIRT1)/核因子-κB(NF-κB)信号通路的影响。方法将60只小鼠随机分为对照组,模型组,丹参酮ⅡA低、高剂量组,SRT1720(SIRT1激活剂)组,丹参酮ⅡA+EX527(SIRT1抑制剂)组,每组10只。除对照组外,其余各组小鼠均每天给予100 mg/kg利福平和100 mg/kg异烟肼连续灌胃30 d构建肝损伤模型。采用全自动生化分析仪检测小鼠血清丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)、总胆红素(TBIL)、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)水平,ELISA法检测血清肿瘤坏死因子α(TNF-α)、白介素1β(IL-1β)水平,免疫组化染色和Western blot法检测小鼠肝组织SIRT1、NF-κB蛋白表达。结果与对照组比较,模型组小鼠血清ALT、AST、TBIL、TC、TG、LDL-C、TNF-α、IL-1β水平及肝组织NF-κB蛋白表达升高(P<0.01),血清HDL-C水平及肝组织SIRT1蛋白表达降低(P<0.01);与模型组比较,丹参酮ⅡA各剂量组和SRT1720组小鼠血清ALT、AST、TBIL、TC、TG、LDL-C、TNF-α、IL-1β水平及肝组织NF-κB蛋白表达降低(P<0.01),血清HDL-C水平及肝组织SIRT1蛋白表达升高(P<0.01)。模型组小鼠肝组织存在损伤,肝细胞大量坏死,且肝组织病理损伤评分高于对照组(P<0.01);丹参酮ⅡA各剂量组和SRT1720组小鼠肝组织损伤得到改善,病理损伤评分低于模型组(P<0.01)。结论丹参酮ⅡA可能通过激活SIRT1/NF-κB信号通路保护抗结核药物引起的小鼠肝损伤。

关键词：丹参酮ⅡA 肝损伤抗结核药物沉默信息调节因子1(SIRT1) 核因子-κB(NF-κB)