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Timescales and contribution of heating and helicity effect in helicity-dependent all-optical switching

Rare Metals 2023年第1期42卷 234-243页

作者： Guan-Qi Li Xiang-Yu Zheng Jun-Lin Wang Xian-Yang Lu Jing Wu Jian-Wang Cai Hao Meng Bo Liu Thomas A.Ostler Yong-bing Xu School of Integrated Circuits Guangdong University of TechnologyGuangzhou510006China york-Nanjing International Joint Center in Spintronics School of Electronic Science and EngineeringNanjing UniversityNanjing210093China Spintronics and Nanodevice Laboratory Department of Electronics EngineeringUniversity of YorkYorkYO105DDUK Institute of Physics Chinese Academy of SciencesBeijing100190China Key Laboratory of Spintronics Materials Devices and System of Zhejiang ProvinceHangzhou311305China College of Business Technology and EngineeringSheffield Hallam UniversitySheffieldS11WBUK

The heating and helicity effects induced by circularly polarized laser excitation are entangled in the helicity-dependent all-optical switching(HD-AOS),which hinders understanding the magnetization dynamics ***,applying a dual-pump laser excitation,first with a linearly polarized(LP) laser pulse followed by a circularly polarized(CP) laser pulse,the timescales and contribution from heating and helicity effects in HD-AOS were identified with a Pt/Co/Pt *** the LP laser pulses preheat the sample to a nearly fully demagnetized state,the CP laser pulses with a power reduced by 80% switch the sample’s *** varying the time delay between the two pump pulses,the results show that the helicity effect,which gives rise to the deterministic helicity-induced switching,arises almost instantly within 200 fs close to the pulse width upon laser *** results reveal that the transient magnetization state upon which CP laser pulses impinge is the key factor for achieving HD-AOS,and importantly,the tunability between heating and helicity effects with the unique dualpump laser excitation approach will enable HD-AOS in a wide range of magnetic material systems having wideranging implications for potential ultrafast spintronics applications.

关键词： Helicity-dependent all-optical switching Ultrafast laser Ultrafast magnetization Magneto-optical interaction

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带极性侧链的环[6]芳酰胺的球形自组装

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物理化学学报 2010年第6期26卷 1557-1564页

作者：杨永安袁立华胡晋川邹树良冯文龚兵四川大学化学学院教育部辐射物理与技术重点实验室原子核科学与技术研究所成都610064 department of chemistry the State University of New Yorkat Buffalo

环芳酰胺是一类基于三中心氢键促进,经寡聚前体一步大环合成法得到的刚性大环分子.通过紫外-可见(UV-Vis)光谱、动态光散射(DLS)、扫描电镜(SEM)、透射电镜(TEM)和原子力显微镜(AFM)等实验手段,详细考察了侧链为三甘醇单甲基醚链,由六... 详细信息

环芳酰胺是一类基于三中心氢键促进,经寡聚前体一步大环合成法得到的刚性大环分子.通过紫外-可见(UV-Vis)光谱、动态光散射(DLS)、扫描电镜(SEM)、透射电镜(TEM)和原子力显微镜(AFM)等实验手段,详细考察了侧链为三甘醇单甲基醚链,由六个苯环单元组成的环[6]芳酰胺的自组装行为.实验结果表明,该大环在1,2-二氯乙烷中发生自组装,其组装聚集体随温度升高产生从聚集体到单分子的解聚变化,至70℃时几乎完全解聚;在由良溶剂(二氯甲烷)和不良溶剂(芳烃类)组成的混合溶剂中,带有三甘醇醚链的环[6]芳酰胺化合物1自组装成微球,结合热稳定性实验和TEM证实是实心微球而非囊泡.进一步发现微球形成和形貌依赖于混合溶剂中不良溶剂的极性和种类,芳烃类溶剂有利于微球形成,而烷烃和极性溶剂则不利,后者更倾向于形成膜的结构.

关键词：自组装环芳酰胺大环三中心氢键

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Synthesis of Flowerlike Zn Nanoplate Aggregates by Vapor Deposition

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Chemical Research in Chinese Universities 2011年第5期27卷 900-902页

作者： RUAN Wei-dong YANG You-ming ZHOU Tie-li NIU Li ZHANG Xin-dong TAO Yan-chun LOMBARDI John R. ZHAO bing state Key Laboratory of Supramolecular Structure and Materials Jilin University Changchun 130012 P. R China Engineering Laboratory for Modern Analytical Techniques State Key Laboratory of Electroanalytical Chemistry Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 P. R. China state Key Laboratory on Integrated Optoelectronies College of Electronic Science and Engineering Jilin University Changehun 130012 P.R. China department of chemistry the City College of New York New York 10031 USA

1 IntroductionIn the very recent years, low-dimensional nanomaterials have attracted a great interest in nanoscience and nanotechnology due to their exciting application in electronics[1], optoelectronics[2] and mecha... 详细信息

关键词： Zinc Nanostructure Vapor deposition

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海洋真菌Aspergillus ***-4中生物碱类代谢产物3.羟基-β-咔啉诱导人肝癌细胞凋亡及其机制

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中国药学杂志 2021年第14期56卷 1160-1166页

作者：汪家龙邱颖冯公侃张海亮胡冰心安徽省黄山职业技术学院医学系安徽黄山245000 中山大学肿瘤防治中心华南肿瘤学国家重点实验室广州510060

目的研究海洋真菌Aspergillus ***-4中生物碱类代谢产物3.羟基-β-咔啉诱导人肝细胞癌细胞凋亡及其作用机制。方法不同浓度的3.羟基-β-咔啉处理肝细胞癌细胞,MTT法和流式细胞术分别检测3.羟基-β-咔啉对细胞增殖和凋亡的影响,Western b... 详细信息

目的研究海洋真菌Aspergillus ***-4中生物碱类代谢产物3.羟基-β-咔啉诱导人肝细胞癌细胞凋亡及其作用机制。方法不同浓度的3.羟基-β-咔啉处理肝细胞癌细胞,MTT法和流式细胞术分别检测3.羟基-β-咔啉对细胞增殖和凋亡的影响,Western blot检测DNA修复酶(PARP)切割,cleaved-caspase3.Bcl2等凋亡相关蛋白和相关通路蛋白ERK、AKT、JNK等磷酸化水平的变化。流式细胞术检测3.羟基-β-咔啉对胞内活性氧(ROS)水平的影响,并检测ROS清除剂对3.羟基-β-咔啉介导的细胞凋亡的影响。结果3.羟基-β-咔啉显著抑制肝细胞癌细胞HepG2、QGY7701和SMMC7721的增殖,PARP断裂条带明显增加,Cleaved-caspase3.白表达上调,抗凋亡蛋白Bcl2表达下调,ERK1/2蛋白磷酸化水平降低。流式细胞术检测发现3.羟基-β-咔啉诱导肝癌细胞凋亡。3.羟基-β-咔啉处理肝癌细胞后胞内ROS水平升高,ROS抑制剂NAC或脂质ROS抑制剂Liproxstatin-1可拮抗3.羟基-β-咔啉诱导的SMMC7721或HepG2细胞的凋亡。结论3.羟基-β-咔啉能够抑制肝癌细胞增殖,升高细胞ROS水平,诱导细胞凋亡。

关键词： 3.羟基-β-咔啉肝细胞癌活性氧细胞凋亡

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芳酰胺类大环一步高效合成及其成环机理研究进展

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物理化学学报 2010年第7期26卷 1811-1822页

作者：胡晋川冯文李向晖杨柳青袁立华何兰龚兵四川大学化学学院、教育部辐射物理与技术重点实验室、原子核科学技术研究所成都610064 department of chemistry University at BuffaloThe State University of New York at BuffaloBuffaloNew York 14260USA 北京师范大学化学学院北京100875

总结了最近发现的新型芳酰胺及芳酰肼大环一步合成反应,着重探讨了由分子内三中心氢键所引导的高效一步成环反应机理.这类反应是由未成环寡聚物前体的折叠构象所构筑,不仅高效,而且反应机理新颖,提供了传统成环反应难以得到的几类刚性... 详细信息

总结了最近发现的新型芳酰胺及芳酰肼大环一步合成反应,着重探讨了由分子内三中心氢键所引导的高效一步成环反应机理.这类反应是由未成环寡聚物前体的折叠构象所构筑,不仅高效,而且反应机理新颖,提供了传统成环反应难以得到的几类刚性大环的合成方法.这些大环化合物表现出对客体识别的高度专一性,并能形成具有高通量性的跨膜孔道.

关键词：一步成环反应机理氢键刚性大环

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口腔颌面部恶性肿瘤颈淋巴清扫术后肩臂综合征的评估与康复管理专家共识

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实用口腔医学杂志 2024年第5期40卷 597-607页

作者：李家存孙沫逸任皎洁郭伟李龙江唐瞻贵任国欣孙志军孟箭尚伟刘绍严张杰李吉辰何悦李春洁杨凯龚忠诚席庆韩冰麦华明陈彦平章杰吴亚东李超安常明孙传政袁华杨帆袁海光吴丹冬范帅李飞徐超魏伟口颌系统重建与再生全国重点实验室国家口腔疾病临床医学研究中心陕西省口腔疾病临床医学研究中心空军军医大学第三附属医院医疗康复科西安710032 口颌系统重建与再生全国重点实验室国家口腔疾病临床医学研究中心陕西省口腔疾病临床医学研究中心空军军医大学第三附属医院口腔颌面头颈肿瘤科陕西省中医医院耳鼻喉科上海交通大学医学院附属第九人民医院口腔颌面-头颈肿瘤科四川大学口腔疾病国家重点实验室国家口腔疾病研究临床中心华西口腔医院头颈肿瘤外科中南大学湘雅口腔医院武汉大学口腔医学院徐州市中心医院青岛大学附属医院口腔颌面外科中国医学科学院肿瘤医院头颈外科北京大学口腔医学院口腔颌面外科哈尔滨医科大学附属第一医院重庆医科大学附属第一医院口腔颌面外科新疆医科大学口腔医学院解放军总医院第一医学中心口腔科吉林大学口腔医院口腔颌面外科广西医科大学附属口腔医院河北医科大学第四医院暨河北省肿瘤医院南昌大学第一附属医院口腔颌面外科贵州医科大学口腔医学院四川省肿瘤医院头颈外科国家癌症中心国家肿瘤临床医学研究中心中国医学科学院北京协和医学院肿瘤医院头颈外科昆明医科大学第三附属医院(云南省肿瘤医院)头颈外二科空军军医大学西京医院康复医学科陕西中医药大学附属医院针灸二科重庆医科大学附属第一医院康复医学科中南大学湘雅三医院康复科解放军总医院第一医疗中心康复医学科广西医科大学第一附属医院康复医学科滨州医学院附属烟台山医院康复医学科

颈淋巴清扫术(ND)是口腔颌面部恶性肿瘤治疗的主要方法之一。尽管颈清术式在不断改良,但术中因剥离、牵拉等损伤副神经、肌肉、肌膜、筋膜及韧带引起的肩臂综合征(SS),仍是患者术后常见并发症,加之放疗的影响,不仅会导致患者肩颈及手臂... 详细信息

颈淋巴清扫术(ND)是口腔颌面部恶性肿瘤治疗的主要方法之一。尽管颈清术式在不断改良,但术中因剥离、牵拉等损伤副神经、肌肉、肌膜、筋膜及韧带引起的肩臂综合征(SS),仍是患者术后常见并发症,加之放疗的影响,不仅会导致患者肩颈及手臂疼痛、僵硬、麻木、活动受限等功能障碍,更会对患者的生存质量和身心健康产生严重影响。目前,国内外针对口腔颌面部恶性肿瘤颈清术后SS的问题尚缺乏一个系统评估和康复管理方案。基于前期临床实践基础以及当前可获得的最佳证据,参考国内外相关文献,邀请颌面肿瘤外科和康复领域的专家根据相关临床经验共同讨论、修改,从SS的病因、评估、诊断与鉴别诊断、康复策略及预防等方面达成共识,以期为临床提供参考。

关键词：口腔颌面部肿瘤颈淋巴清扫术肩臂综合征康复管理

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地塞米松诱导新西兰兔先天性腭裂的非靶向代谢组学研究

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中华口腔医学杂志 2023年第9期58卷 938-943页

作者：林兰玲刘皓月罗枭郑谦石冰龚萌李承浩四川大学华西口腔医院唇腭裂外科、口腔疾病防治全国重点实验室、国家口腔医学中心国家口腔疾病临床医学研究中心成都610041

目的应用非靶向代谢组学技术比较地塞米松干预后的腭裂胚胎、非腭裂胚胎与正常胚胎在腭突发育期间胎盘组织的差异。方法将12只孕兔(40周龄,体质量4.5~5.0 kg的雌性新西兰兔)按照随机数表法分为地塞米松组(8只)和对照组(4只),在妊娠第13...

目的应用非靶向代谢组学技术比较地塞米松干预后的腭裂胚胎、非腭裂胚胎与正常胚胎在腭突发育期间胎盘组织的差异。方法将12只孕兔(40周龄,体质量4.5~5.0 kg的雌性新西兰兔)按照随机数表法分为地塞米松组(8只)和对照组(4只),在妊娠第13.16天每日分别给两组孕兔后腿四头肌肌肉注射1次1.0 mg地塞米松和1 ml生理盐水,并于妊娠第21天处死孕兔,剖腹取其子代,按照子代腭部表型分为3.,分别为地塞米松腭裂组、地塞米松非腭裂组(经地塞米松未诱导腭裂)和正常对照组,再收集胎盘组织样本。应用液相色谱—三重串联四级杆液质联用仪获取胚胎胎盘组织样本的相应图谱,主成分分析法描绘3.胚胎胎盘组织代谢产物在胚胎腭突发育阶段的代谢差异。结果地塞米松腭裂组、地塞米松非腭裂组和正常对照组之间存在明显的代谢差异,差异代谢物共13.种(VIP>1,P3.8、1.3.9±0.3.2)、半乳糖(分别为0.888±0.171、1.03.±0.182、1.127±0.127)、赖氨酸(分别为1.551±0.924、1.789±1.43.、0.541±0.424)和尿素(分别为0.743.0.142、1.13.±0.3.1、1.171±0.457)差异均有统计学意义(F=5.90,P=0.008;F=5.59,P=0.009;F=4.26,P=0.025;F=5.29,P=0.012)。结论基于胎盘组织代谢物建立的统计模型表明,3.胚胎胎盘组织的代谢物表达具有差异;地塞米松诱导腭裂形成可能与维生素B6代谢、赖氨酸代谢、精氨酸合成代谢、半乳糖代谢高度相关。

关键词：地塞米松先天性腭裂新西兰兔代谢组学

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Pilot study on efficacy of reduced cathartic bowel preparation with polyethylene glycol and bisacodyl

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World Journal of Gastroenterology 2013年第4期19卷 561-568页

作者： Zhi-Yuan Chen He-Song Shen Ming-Yue Luo Chai-Jie Duan Wen-Li Cai Hong-bing Lu Guo-Peng Zhang Yang Liu Jerome Z Liang department of Radiology the Sixth Affiliated Hospital of Sun Yat-Sen University department of Radiology Guangdong Provincial Hospital of Traditional Chinese Medicine Research Center of Biomedical Engineering Graduate School at ShenzhenTsinghua University department of Radiology Massachusetts General Hospital and Harvard Medical SchoolBostonMA 02114United States department of Biomedical Engineering The Fourth Military Medical University departments of Radiology and Computer Science State University of New York at Stony BrookNew YorkNY 11794United States

AIM:To evaluate the efficacy of reduced cathartic bowel preparation with 2 L polyethylene glycol(PEG)-4000 electrolyte solution and 10 mg bisacodyl enteric-coated tablets for computed tomographic colonography(CTC).METHODS:Sixty subjects who gave informed consent were randomly assigned to study group A,study group B or the control *** the day prior to CTC,subjects in study group A were given 20 mL 40% wt/vol barium sulfate suspension before 3.mealtimes,60 mL 60% diatrizoate meglumine diluted in 250 mL water after supper,and 10 mg bisacodyl enteric-coated tablets 1 h before oral administration of 2 L PEG-4000 electrolyte *** in study group B were treated identically to those in study group A,with the exception of bisacodyl which was given 1 h after oral *** in the control group were managed using the same strategy as the subjects in study group A,but without administration of *** stool and fluid scores,the attenuation value of residual fluid,and discomfort during bowel preparation in the three groups were analyzed ***:The mean scores for residual stool and fluid in study group A were lower than those in study group B,but the differences were not statistically *** in study group A showed greater stool and fluid cleansing ability than the subjects in study group *** mean scores for residual stool and fluid in study groups A and B were lower than those in the control group,and were significantly *** was no significant difference in the mean attenuation value of residual fluid between study group A,study group B and the control *** total discomfort index during bowel preparation was 46,45 and 45 in the three groups,respectively,with no significant ***:Administration of 10 mg bisacodyl enteric-coated tablets prior to or after oral administration of 2 L PEG-4000 electrolyte solution enhances stool and fluid cleansing ability,and has no impact on the atten

关键词： Colorectal cancer Screening Computed tomographic colonography Polyethylene glycol Bisacodyl

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Attributable Causes of Breast Cancer and Ovarian Cancer in China:Reproductive Factors,Oral Contraceptives and Hormone Replacement Therapy

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Chinese Journal of Cancer Research 2012年第1期24卷 9-17页

作者： Li Li Jia JI Jian-bing Wang Mayineur Niyazi You-lin Qiao Paolo Boffettas Deportment of Gynecology the People's Hospitul of Xinjiung Uygur Autonomous RegionUrumqi 830011China department of Cancer Epidemiology Cancer InstituteChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100021China Division of Pharmaceutics College of Pharmacythe Ohio State UniversityColumbusOH 43210USA department of Epidemiology and Statistics Institute of Basic Medical SciencesChinese Academy of Medical Sciences&School of Basic MedicinePeking Union Medical CollegeBeijing 100730China The Tisch Cancer Institute Mount Sinai School of MedicineNew YorkNY 10029USA International Prevention Research Institute Lyon 69006France

Objective： To provide an evidence-based, consistent assessment of the burden of breast cancer attributable to reproductive factors （RFs, including nulliparity, mean number of children, age at first birth and breastfeeding）, use of oral contraceptives （OCs, restricted to the age group of 15-49 years）, and hormone replacement therapy （HRT）, as well as of the burden of ovarian cancer attributable to the mean number of children in China in 2005. Methods： We derived the prevalence of these risk factors and the relative risk of breast and ovarian cancer from national surveys or large-scale studies conducted in China. In the case of RFs, we compared the exposure distributions in 2001 and counterfactual exposure. Results： Exposure of RFs in 2002 was found to account for 6.74% of breast cancer, corresponding to 9,617 cases and 2,769 deaths, and for 2.78% of ovarian cancer （712 cases, 294 deaths）. The decrease in mean number of children alone was responsible for 1.47% of breast cancer and 2.78% of ovarian cancer. The prevalence of OC use was 1.74% and the population attributable fraction （PAF） of breast cancer was 0.71%, corresponding to 3.0 cases and 90 deaths. The PAF of breast cancer due to HRT was 0.3.%, resulting in 297 cases and 85 deaths. Conclusion： RFs changes in China contributed to a sizable fraction of breast and ovarian cancer incidence and mortality, whereas HRT and OCs accounted for relatively low incidence of breast cancer in China.

关键词： Reproductive factors Oral contraceptives Hormone replacement therapy Cancer Population attributable fraction

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Epidemics of overweight and obesity among growing childhood in China between 1997 and 2009： Impact of Family Income, Dietary Intake, and Physical Activity Dynamics

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Chinese Medical Journal 2015年第14期128卷 1879-1886页

作者： Chang Su bing Zhang You-Fa Wang Xiao-Fang Jia Hong Xue Hui-Jun Wang department of Public Health Nutrition and Nutrition Policy National Instiute for Nutrition and Health Chinese Center for Disease Control and Prevention Beijing 100050 China System-oriented Global Childhood Obesity Intervention Program Department of Epidemiology and Environmental Health School of Public Health and Health Professions University at Buffalo State University of New York New York USA

Background： Obesity has become a major health problem among children and adolescents worldwide. This study aimed to examine the trends of overweight and obesity among childhood in China and assess their associations with family income, dietary intake, and physical activity （PA） between 1997 and 2009. Methods： Two waves of cross-sectional data of Chinese children and adolescents aged 7-17 years from the China Health and Nutrition Survey were used. Weight and height were measured following standardized procedures. Dietary intake was assessed by 3.consecutive 24-h recalls. Childhood overweight and obesity were defined using the International Obesity Task Force-recommended body mass index cut-offs. Multivariate linear regression analysis was used to examine the associations of family income with diet intakes and PA. Multivariate logistic regression analysis was conducted to assess the associations of overweight and obesity with family income, dietary intake, and PA. Results： The prevalence of childhood overweight and obesity increased from 12.6% in 1997 to 22.1% in 2009, particularly in the medium- and high-family income groups, which increased by 102.7% and 90.3., respectively. Higher fat intake （% energy）, and moderate and vigorous PA were significantly associated with overweight and obesity in final model （odds ratio [OR] = 1.01, 95% confidence interval [CI]： 1.00-1.02, P = 0.004; and OR = 0.99, 95% CI： 0.98-1.00, P = 0.03., respectively）. Conclusions： The prevalence of overweight and obesity among Chinese children and adolescents has increased between 1997 and 2009. Reducing fat intake and increasing PA may help obesity prevention.

关键词： Adolescent Child Dietary Intake Income Obesity Overweight Physical Activity

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