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Monitoring the Hydrolysis of Olive Oil Catalyzed by Lipase via Acid Value Detection

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Chemical Research in Chinese Universities 2007年第2期23卷 196-199页

作者： gao Gui zheng liang-yu ZHANG Zuo-ming HAN Si-ping CAO Sui-gui Key Laboratory of Molecular Enzymology and Engineering of Ministry of Education Jilin University Changchun 130021 P. R. China

Hydrolysis of olive oil catalyzed by Candida lipolytica lipase was investigated. The relative concentration of the components in the product was determined by using high performance liquid chromatography（HPLC）. Furthermore, a novel rapid method to detect the hydrolytic process of olive oil was developed based on the relationship between the acid value and the relative concentration of the different components.

关键词： Lipase Hydrolysis Olive oil Glyeefide Acid value

Early chatter identification based on optimized VMD with multi-band information fusion and compression method in robotic milling process

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Chinese Journal of Aeronautics 2024年第6期37卷 464-484页

作者： Sichen CHEN Zhiqiang liang Yuchao DU Zirui gao Haoran zheng Zhibing LIU Tianyang QIU Xibin WANG School of Mechanical Engineering Beijing Institute of TechnologyBeijing 100081China Beijing Institute of Technology Chongqing Innovation Center Chongqing 401120China

Undesirable self-excited chatter has always been a typical issue restricting the improvement of robotic milling quality and *** chatter identification based on processing signals can prompt operators to adjust the machining process and prevent chatter *** with the traditional machine tool,the uncertain multiple chatter frequency bands and the band-moving of the chatter frequency in robotic milling process make it more challenging to extract chatter *** paper proposes a novel method of chatter identification using optimized variational mode decomposition(OVMD)with multi-band information fusion and compression technology(MT).During the robotic milling process,the number of decomposed modes k and the penalty coefficient a are optimized based on the dominant component of frequency scope partition and fitness of the mode center ***,the mayfly optimization algorithm(MA)is employed to obtain the global optimal parameter *** order to conquer information collection about the uncertain multiple chatter frequency bands and the band-moving of the chatter frequency in robotic milling process,MT is presented to reduce computation and extract signal ***,the cross entropy of the image(CEI)is proposed as the final chatter indicator to identify the chatter *** robotic milling experiments are carried out to verify the proposed method,and the results show that it can distinguish the robotic milling condition by extracting the uncertain multiple chatter frequency bands and overcome the band-moving of the chatter frequency in robotic milling process.

关键词： Robotic milling Chatter detection Variational mode decomposition Information fusion and compression Chatter featur

Orthogonal Combinatorial Raman Codes Enable Rapid High-Throughput-Out Library Screening of Cell-Targeting Ligands

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Research 2024年第1期2023卷 199-208页

作者： Yuchen Tang Xingxing zheng Tingjuan gao China Key Laboratory of Pesticide and Chemical Biology of Ministry of Education College of ChemistryCentral China Normal UniversityWuhan 430079China

High-throughput assays play an important role in the fields of drug discovery,genetic analysis,and clinical *** super-capacity coding strategies may facilitate labeling and detecting large numbers of targets in a single assay,practically,the constructed large-capacity codes have to be decoded with complicated procedures or are lack of survivability under the required reaction *** challenge results in either inaccurate or insufficient decoding ***,we identified chemical-resistant Raman compounds to build a combinatorial coding system for the high-throughput screening of cell-targeting ligands from a focused 8-mer cyclic peptide *** accurate in situ decoding results proved the signal,synthetic,and functional orthogonality for this Raman coding *** orthogonal Raman codes allowed for a rapid identification of 63 positive hits at one time,evidencing a high-throughput-out capability in the screening *** anticipate this orthogonal Raman coding strategy being generalized to enable efficient high-throughput-out screening of more useful ligands for cell targeting and drug discovery.

关键词： enable throughput allowed

Heat Shock Factor A1s are required for phytochrome-interacting factor 4-mediated thermomorphogenesis in Arabidopsis

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Journal of Integrative Plant Biology 2024年第1期66卷 20-35页

作者： Bingjie Li Shimeng Jiang liang gao Wenhui Wang Haozheng Luo Yining Dong Zhihua gao Shuzhi zheng Xinye Liu Wenqiang Tang Key Laboratory of Molecular and Cellular Biology of Ministry of Education Hebei Research Center of the Basic Discipline of Cell BiologyHebei Collaboration Innovation Center for Cell SignalingHebei Key Laboratory of Molecular and Cellular BiologyCollege of Life SciencesHebei Normal UniversityShijiazhuang 050024China School of Information Technology Hebei University of Economics and BusinessShijiazhuang 050061China

Thermomorphogenesis and the heat shock(HS)response are distinct thermal responses in plants that are regulated by PHYTOCHROME-INTERACTING FACTOR 4(PIF4)and HEAT SHOCK FACTOR A1s(HSFA1s),*** is known about whether these responses are interconnected and whether they are activated by similar *** analysis of transcriptome dynamics in response to warm temperature(28℃)treatment revealed that 30 min of exposure activated the expression of a subset of HSFA1 target genes in Arabidopsis ***,a loss-of-function HSFA1 quadruple mutant(hsfa1-cq)was insensitive to warm temperature-induced hypocotyl *** hsfa1-cq plants grown at 28℃,the protein and transcript levels of PIF4 were greatly reduced,and the circadian rhythm of many thermomorphogenesis-related genes(including PIF4)was ***,the nuclear localization of HSFA1s and the binding of HSFA1d to the PIF4 promoter increased following warm temperature exposure,whereas PIF4 overexpression in hsfa1-cq partially rescued the altered warm temperature-induced hypocotyl growth of the *** together,these results suggest that HSFA1s are required for PIF4 accumulation at a warm temperature,and they establish a central role for HSFA1s in regulating both thermomorphogenesis and HS responses in Arabidopsis.

关键词： HSFA1 PIF4 thermomorphogenesis

Universal origin of glassy relaxation as recognized by configuration pattern matching

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National Science Review 2024年第5期11卷 343-351页

作者： Hai-Bin Yu liang gao Jia-Qi gao Konrad Samwer Wuhan National High Magnetic Field Center and School of Physics Huazhong University of Science and Technology I.Physikalisches Institut Universit?t G?ttingen

Relaxation processes are crucial for understanding the structural rearrangements of liquids and amorphous materials. However, the overarching principle that governs these processes across vastly different materials remains an open question. Substantial analysis has been carried out based on the motions of individual particles. Here, as an alternative, we propose viewing the global configuration as a single entity. We introduce a global order parameter, namely the inherent structure minimal displacement(IS Dmin), to quantify the variability of configurations by a pattern-matching technique. Through atomic simulations of seven model glass-forming liquids, we unify the influences of temperature, pressure and perturbation time on the relaxation dissipation, via a scaling law between the mechanical damping factor and IS Dmin. Fundamentally,this scaling reflects the curvature of the local potential energy landscape. Our findings uncover a universal origin of glassy relaxation and offer an alternative approach to studying disordered systems.

关键词： glass transition metallic glass relaxation dynamics mechanical spectroscopy internal friction

An Integrated External Archive Local Disturbance Mechanism for Multi-Objective Snake Optimizer

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Chinese Journal of Electronics 2024年第4期33卷 989-996页

作者： Leifu gao zheng LIU Institute for Optimization and Decision Analytics Liaoning Technical University

It is an interesting research direction to develop new multi-objective optimization algorithms based on meta-heuristics. Both the convergence accuracy and population diversity of existing methods are not *** paper proposes an integrated external archive local disturbance mechanism for multi-objective snake optimizer(IMOSO) to overcome the above shortcomings. There are two improved strategies. The adaptive mating between subpopulations strategy introduces the special mating behavior of snakes with multiple husbands and wives into the original snake optimizer. Some positions are updated according to the dominated relationships between the newly created individuals and the original individuals. The external archive local disturbance mechanism is used to re-search partial non-inferior solutions with poor diversities. The perturbed solutions are non-dominated sorting with the generated solutions by the next iteration to update the next external archive. The main purpose of this mechanism is to make full use of the non-inferior solution information to better guide the population evolution. The comparison results of the IMOSO and 7 state-of-the-art algorithms on WFG benchmark functions show that IMOSO has better convergence and population diversity.

关键词： Accuracy Sociology Metaheuristics Diversity methods Benchmark testing Statistics Convergence

Water and other volatiles on Mars

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National Science Review 2024年第6期11卷 12-14页

作者： Sen Hu Yubing gao Zhan Zhou liang gao Yangting Lin Key Laboratory of the Earth and Planetary Physics Institute of Geology and GeophysicsChinese Academy of Sciences College of Earth and Planetary Sciences University of Chinese Academy of Sciences

Mars, the intriguing red planet, is one of the planets most similar to the Earth in our solar system. It is widely accepted that Mars could have had a warm and wet climate in its early history supported by numerous lines of evidence, e.g. topography, canyons, outflow channels, presence of phyllosilicates and evaporative salts,sedimentary formation, and many others (e.g.[1]), and thus Mars is believed to once have a potentially habitable environment which could be able to supply fundamental conditions for the evolution of potential lives.

关键词： ISOTOPIC COMPOSITION MARTIAN ATMOSPHERE SUBSURFACE WATER ABUNDANCE TISSINT H2O CO2

Stimulating Start-up Investment Through Government-Sponsored Venture Capital: Theory and Chinese Evidence

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Journal of Systems Science & Complexity 2024年第5期37卷 2021-2053页

作者： NI Xuanming zheng Tiantian gao Feng ZHAO Huimin School of Software and Microelectronics Peking University School of Economics and Management Tsinghua University School of Business Sun Yat-sen University

Government-sponsored venture capital(GVC) has been used to support financially constrained start-ups as an important policy tool in China. Typically, to motivate the social capital to invest in start-ups, GVC provides subsidies for them to bridge the funding gap in the early-stage venture capital market. However, the effect and mechanism of GVC affecting social capital investment have not been clearly studied. In this paper, the authors not only develop a game model to analyze this issue in theory, but conduct an empirical study by analyzing the 14741 records matched by propensity score matching(PSM) of Chinese venture capital market data from 2011 to 2021. The proposed findings are as the follows. Firstly, the subsidies offered by GVC will simultaneously increase the returns and risks of investments in start-ups of social capital with more volatile incentive effect of GVC. The incentive effect of GVC is only effective when the returns resulting from the subsidies outweigh the risks they introduce. In the context of the Chinese venture capital market, the incentive effect of GVC is effective. Secondly, the incentive effect of GVC is more pronounced in high-tech industries, which can be attributed to the signaling effect facilitated by GVC. In this context, the subsidy mainly helps social capital to bear the costs associated with screening potential investments. Thirdly, the incentive effect of GVC is more significant in underdeveloped venture capital markets, which can be explained by the “virtuous cycle” effect, in which GVC plays a pioneering role in establishing a more robust early-stage market trading system. By examining these three points, this study contributes to a better understanding of how GVC can effectively guide social capital investment, especially in the Chinese landscape.

关键词： Government-sponsored venture capital fund incentive effect social capital subsidy venture capital

Creating one-line hybrid crops by synthetic apomixis

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Molecular Plant 2024年第1期17卷 16-18页

作者： Ronghong liang Caixia gao New Cornerstone Science Laboratory Center for Genome EditingInstitute of Genetics and Developmental BiologyChinese Academy of SciencesBeijing100101China College of Advanced Agricultural Sciences University of Chinese Academy of SciencesBeijing100049China

Hybrid breeding plays an important role in increasing crop yields by taking advantage of hybrid vigor,which helps crops grow with superior yields across various climates and contributes to ensuring secure food *** seed production is relatively straightforward and simple in cross-pollinating plants such as maize but is difficult in self-pollinating plants such as rice,wheat,and ***,breeders have developed a three-line breeding strategy,utilizing a sterile line,a maintainer line,and a restorer line,for breeding hybrid rice(Figure 1A;Yuan,1966).

关键词： breeding crops sterile