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Overexpression of the angiogenic tetrapeptide AcsDKP and the prolyl oligopeptidase（POP）is a common feature of cancer

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Overexpression of the angiogenic tetrapeptide AcSDKP and the...

A NOVEL rEACTION BETWEEN ge-ge AND Fe-Fe BONDs IN COMPLEX (me_2gegeme_2)[(η￣5 - C_5H_4) Fe(CO)]_2(μ- CO)_2 AND CrYsTAL sTrUCTUrE OF THE PrODUCT

第十一次中国生物物理学术大会暨第九届全国会员代表大会

作者： Jéröme Bignon Alexia Pinault Joanna Wdzieczak-Bakala Institut de Chimie des substances Naturelles

＜正＞Prolyl oligopeptidase（POP）is a cytosolic enzyme involved in the metabolism of many peptide hormones and neuropeptides（1）.It was recently reported that POP is responsible in

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Chinese Chemical Letters 1996年第4期7卷 385-386页

作者： Zhou X.Z. Xie W.H. Xu s.s. Department of Chemisty Nankai University Tianjin 300071

me2gegeme2)[(η￣5-C_5H_4)Fe(CO)]_2(μ-CO)_2, 1 undergoes a novel reaction between its ge-ge and Fe-Fe bonds, forming a rearrangement product with a new cyclic structure,[me_2ge(η￣5- C_5H_4)Fe(CO)_2]_2, 2, which was...

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Low-loss single-mode hybrid-lattice hollow-core photonic-crystal fibre

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Light(science & Applications) 2021年第1期10卷 86-97页

作者： Foued Amrani Jonas HOsorio Frederic Delahaye Fabio giovanardi Luca Vincetti Benoit Debord Frederic gerome Fetah Benabid gPPMM group XLIM InstituteCNRS UMR 7252University of LimogesLimoges 87060France gLOphotonics 123 Avenue Albert ThomasLimoges 87060France Department of Engineering menzo Ferrari University of Modena and Reggio EmiliaModena 41125Italy

remarkable recent demonstrations of ultra-low-loss inhibited-coupling(1C)hollow-core photonic-crystal fibres(HCPCFs)established them as serious candidates for next-generation long-haul fibre optics systems.A hindrance to this prospect and also to short-haul applications such as micromachining,where stable and high-quality beam delivery is needed,is the difficulty in designing and fabricating an IC-guiding fibre that combines ultra-low loss,truly robust single-modeness,and polarisation-maintaining *** design solutions proposed to date require a trade-off between low loss and truly ***,we propose a novel IC-HCPCF for achieving low-loss and effective single-mode *** fibre is endowed with a hybrid cladding composed of a Kagome-tubular lattice(HKT).This new concept of a microstructured cladding allows us to significantly reduce the confinement loss and,at the same time,preserve truly robust single-mode *** results show an HKT-IC-HCPCF with a minimum loss of 1.6dB/km at 1050 nm and a higher-order mode extinction ratio as high as 47.0 dB for a 10 m long *** robustness of the fibre single-modeness is tested by moving the fibre and varying the coupling *** design proposed herein opens a new route for the development of HCPCFs that combine robust ultra-low-loss transmission and single-mode beam delivery and provides new insight into IC guidance.

关键词： fibre mode lattice

Understanding the multifaceted etiopathogenesis of foot complications in individuals with diabetes

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World Journal of Clinical Cases 2023年第8期11卷 1669-1683页

作者： Tatjana Matijević Jasminka Talapko Tomislav meštrović Marijan Matijević suzana Erić Ivan Erić IvanaŠkrlec Department of Dermatology and Venereology University Hospital Center OsijekOsijek 31000Croatia Faculty of Dental medicine and Health Josip Juraj Strossmayer University of OsijekOsijek 31000Croatia University Centre Varaždin University NorthVaraždin 42000Croatia Institute for Health metrics and Evaluation and the Department for Health metrics sciences University of Washington School of MedicineSeattleWA 98195United States Department of surgery National Memorial Hospital VukovarVukovar 32000Croatia Faculty of medicine Josip Juraj Strossmayer University of OsijekOsijek 31000Croatia Department of radiotherapy and Oncology Clinical Hospital Center OsijekOsijek 31000Croatia Department of surgery Osijek University Hospital CentreOsijek 31000Croatia

Diabetes mellitus,a chronic disease of metabolism,is characterized by a disordered production or cellular utilization of *** foot disease,which comprises the spectrum of infection,ulceration,and gangrene,is one of the most severe complications of diabetes and is the most common cause of hospitalization in diabetic *** aim of this study is to provide an evidence-based overview of diabetic foot *** to neuropathy,diabetic foot infections can occur in the form of ulcers and minor skin *** patients with diabetic foot ulcers,ischemia and infection are the main causes of non-healing ulcers and *** compromises the immune system of individuals with diabetes,leading to persistent inflammation and delayed wound *** addition,the treatment of diabetic foot infections is challenging due to difficulty in accurate identification of pathogenic microorganisms and the widespread issue of antimicrobial *** a further complicating factor,the warning signs and symptoms of diabetic foot problems can easily be *** associated with diabetic foot complications include peripheral arterial disease and osteomyelitis;accordingly,the risk of these complications in people with diabetes should be assessed *** antimicrobial agents represent the mainstay of treatment for diabetic foot infections,if peripheral arterial disease is present,revascularization should be considered to prevent limb amputation.A multidisciplinary approach to the prevention,diagnosis,and treatment of diabetic patients,including those with foot ulcers,is of the utmost importance to reduce the cost of treatment and avoid major adverse consequences such as amputation.

关键词： Diabetic foot Diabetes mellitus Foot ulcer Infection Peripheral arterial disease

The significance of midsummer movements of Autographa gamma： Implications for a mechanistic understanding of orientation behavior in a migrant moth

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Current Zoology 2013年第3期59卷 360-370页

作者： Jason W. CHAPMAN Ka s. LIM Don r. rEYNOLDs Department ofAgroEcology Rothamsted Research Harpenden Hertfordshire AL5 2JQ UK Environment and sustainability Institute University of Exeter Penryn Cornwall TR10 9EZ UK Natural resources Institute University of Greenwich Chatham Kent ME4 4TB UK

The silver Y moth Autographa gamma undertakes windbome spring and fall migrations between winter breeding re- gions around the mediterranean and summer breeding regions in northern Europe. Flight behaviors facilitating these migrations include：（i） selection of seasonally-favorable tailwinds; （ii） flying at the altitude of the fastest winds; （iii） adopting flight headings that partially counteract crosswind drift; and （iv） seasonal reversal of preferred directions between spring and fall. In the UK, ra- dar measurements indicate that migratory activity is pronounced during the spring and fall, but is usually very low during mid- summer （July）. However, an atypically intense period of high-altitude flight was recorded during July 2006, and in this study we compare the flight behavior of A. gamma during these midsummer movements with the more typical spring and fall migrations. During July 2006, activity was most intense at significantly lower altitudes than occurred in spring or fall, and was not associated with the height of the fastest winds; consequently displacement speeds were significantly slower. The most striking difference was an absence of tailwind selectivity in July with windborne movements occurring on almost every night of the month and on tailwinds from all directions. Finally, orientation behavior was quantitatively different during July, with significantly greater dis- persion of flight headings and displacements than observed in spring and fall. We discuss mechanisms which could have caused these differences, and conclude that a lack of appropriate photopcriod cues during development of the summer generation resulted in randomly-oriented ＇dispersive＇ movements that were strikingly different from typical seasonal migrations .

关键词： Long-range migration Dispersal High-altitude flight Photoperiod Entomological radar Noctuid moths

Intelligent modular design with holonic fuzzy agents

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Advances in Manufacturing 2021年第1期9卷 81-103页

作者： Egon Ostrosi Alain-Jérome Fougères Zai-Fang Zhang Josip stjepandic University of Technology of Belfort Montbé1iard ERCOS/ELLIADD EA4661University Burgundy-Franche-Comté90010 BelfortFrance school of Engineering ECAM RennesBruz CS 2912835091 RennesFrance school of mechatronic Engineering and Automation Shanghai UniversityShanghai 200240People's Republic of China PrOsTEP Ag Dolivostr.1164293 DarmstadtGermany

Presently,modular designs use various technologies accompanied by multiple *** no integral solution is known,a plethora of approaches is used to resolve this trans disciplinary challenge,often by using local ***,the effective utilization of multiple models requires proper integration for them to work together as a cohesive *** requirement calls for the development of intelligent models and tools that can be used for the development of intelligent modular *** design based on these intelligent models and tools is called intelligent modular *** modular design requires to be considered both dynamically and holistically by combining customer requirements,product functions,solutions,service specifications,and their fuzziness in order to structure a product into intelligent *** paper proposes the use of holonic fuzzy agents to fulfill both the properties of intelligent models and the requirements of intelligent modular *** set of fuzzy function agents and their corresponding fuzzy solution agents are found from customization of the product-service system in the fuzzy function agent-fuzzy solution agent *** the basis of attractor agent recognition,the fuzzy function and fuzzy solution agents interact to form the holonic fuzzy module *** of holonic fuzzy module agents,which is the fundamental property of the holonic structure,is also characterized by vertical and horizontal *** flexibility and agility of the software agent make the holonic structure of intelligent modules *** application illustrates the proposed intelligent modular design.

关键词： Modularity Modular design Intelligent design Holonic agents Product platform Product variety

Image Acquisition and Parameter Calculations for Optimization of the Automatic Identification of Terpenes in a Combined Laser Thin Film Extract

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Advances in Materials Physics and Chemistry 2022年第6期12卷 141-154页

作者： Theodore guié Toa Bi Wognin Vangah Alico Nango Jérôme sié Ouattara Alain Clement UFr science and Technology University of Man Man Ivory Coast Laboratory of Communication and Information science and Technology (LsTCI) National Polytechnic Institute Houphou&euml t Boigny Yamoussoukro C&ocirc te d’Ivoire University Institute of Technology of Angers (IUT) Angers France

In this work, we propose an original approach to the thin-layer identification of secondary metabolites (terpenes) based on the acquisition of multicomponent images integrating terpenes to be identified. Its principle consists initially of segmentation by region of each component of the image based on the attribute tuples or colors of each region of the digital image. Then we proceeded to the calculations of region parameters such as standard deviation, entropy, average pixel color, eccentricity from an algorithm on the matlab software. These values allowed us to build a database. Finally, we built an algorithm for identifying secondary metabolites (terpenes) on the basis of these data. The relevance of our method of identifying or recognizing terpenes has been demonstrated compared to other methods, such as the one based on the calculation of frontal ratios which cannot discriminate between two terpenes having the same frontal ratio. The robustness of our method with respect to the identification of linalool, limonene was tested.

关键词： Thin Film Terpenes segmentation Entropy

High Q and sub-wavelength THz electric field confinement in ultrastrongly coupled THz resonators

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光子学研究:英文版 2023年第7期11卷 1203-1216页

作者： sIMON messELOT sOLEN COEYMANs JErOme TIgNON sUKHDEEP DHILLON JULIETTE MANgENEY Laboratoire de Physique de l’Ecole Normale supérieure Ecole normale supérieurePSL UniversitySorbonne UniversitéUniversitéParis DiderotSorbonne Paris CitéCNRS24 rue Lhomond75005 ParisFrance

The control of light–matter coupling at the single electron level is currently a subject of growing interest for the development of novel quantum devices and for studies and applications of quantum *** the terahertz(THz)spectral range,this raises the particular and difficult challenge of building electromagnetic resonators that can conciliate low mode volume and high quality ***,we report on hybrid THz cavities based on ultrastrong coupling between a Tamm cavity and an LC circuit metamaterial and show that they can combine high quality factors of up to Q=37 with a deep-subwavelength mode volume of V=3.2×10^(-4)λ^(3).Our theoretical and experimental analysis of the coupled mode properties reveals that,in general,the ultrastrong coupling between a metamaterial and a Fabry–Perot cavity is an effective tool to almost completely suppress radiative losses and,thus,ultimately limit the total losses to the losses in the metallic *** Tamm cavity-LC metamaterial coupled resonators open a route toward the development of single photon THz emitters and detectors and to the exploration of ultrastrong THz light–matter coupling with a high degree of coherence in the few to single electron limit.

关键词： coupling cavity coupled

Exploring suitable Applications for Doubly-Fed Asynchronous Machines

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Exploring Suitable Applications for Doubly-Fed Asynchronous ...