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Matricellular proteins as possible biomarkers for early brain injury after aneurysmal subarachnoid hemorrhage

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Neural Regeneration Research 2018年第7期13卷 1175-1178页

作者： Hidenori Suzuki Hirofumi Nishikawa fumihiro kawakita Department of Neurosurgery Mie University Graduate School of Medicine

Aneurysmal subarachnoid hemorrhage remains devastating,and the most important determinant of poor outcome is early brain injury（EBI）.In clinical settings,as a surrogate marker of EBI,loss of consciousness at ictus,poor initial clinical grades,and some radiographic findings are used,but these markers are somewhat ***,it is imperative to find biomarkers of EBI that have beneficial prognostic and therapeutic *** our opinion,an ideal biomarker is a molecule that is implicated in the pathogenesis of both EBI and subsequently developing delayed cerebral ischemia（DCI）,being a therapeutic target,and can be measured easily in the peripheral blood in an acute stage.A good candidate of such a biomarker is a matricellular protein,which is a secreted,inducible and multifunctional extracellular matrix *** are many kinds of matricellular proteins reported,but only tenascin-C,osteopontin,galectin-3 and periostin are reported relevant to EBI and *** biomarkers of EBI may stratify aneurysmal subarachnoid hemorrhage patients into categories of risk to develop DCI,and allow objective monitoring of the response to treatment for EBI and earlier diagnosis of *** review emphasizes that further investigation of matricellular proteins as an avenue for biomarker discovery is warranted.

关键词： biomarker early brain injury galectin-3 matricellular protein osteopontin periostin subarachnoid hemorrhage tenascin-C

Tenascin-C in aneurysmal subarachnoid hemorrhage: deleterious or protective?

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Neural Regeneration Research 2016年第2期11卷 230-231页

作者： Hidenori Suzuki fumihiro kawakita Department of Neurosurgery Mie University Graduate School of Medicine

Subarachnoid hemorrhage（SAH）caused by the rupture of a cerebral aneurysm is a well-known devastating cerebrovascular ***-SAH brain is vulnerable,associated with early brain injury（EBI;Suzuki,2015）.

关键词： SAH Tenascin-C in aneurysmal subarachnoid hemorrhage

A Hopf Type Classification Theorem for Isovariant Maps from Free G-manifolds to Representation Spheres

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Acta Mathematica Sinica,English Series 2011年第4期27卷 685-700页

作者： Ikumitsu NAGASAKI fumihiro USHITAKI Department of Mathematics Kyoto Prefectural University of Medicine Nishitakatsukasa-cho Taishogun Kita-ku Kyoto 603-8334 Japan Department of Mathematics Faculty of Science Kyoto Sangyo University Kamigamo Motoyama Kita-ku Kyoto 603-8555 Japan

An isovariant map is an equivariant map preserving the isotropy subgroups. In this paper, we develop an isovariant version of the Hopf classification theorem; namely, an isovariant homotopy classification result of G-isovariant maps from free G-manifolds to representation spheres under a certain dimensional condition, the so-called Borsuk-Ulam inequality. In order to prove it, we use equivariant obstruction theory and the multidegree of an isovariant map.

关键词： Hopf classification theorem Borsuk Ulam theorem isovariant map multidegree finitegroup action

Effect of multifunction cavitation using phosphoric acid on fatigue and surface properties of AZ31 magnesium alloy

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Journal of Magnesium and Alloys 2023年第6期11卷 1996-2005页

作者： Shunta Matsuoka fumihiro Kato Toshihiko Yoshimura Masataka Ijiri Shoichi Kikuchi Graduate School of Integrated Science and Technology Shizuoka University3-5-1 JohokuNaka-kuHamamatsuShizuoka432-8561Japan Department of Mechanical Engineering Sanyo-Onoda City University1-1-1 Daigaku-DoriSanyo-OnodaYamaguchi 756-0884Japan Tokyo Metropolitan University 1-1 Minami-OsawaHachiojiTokyo 192-0397Japan Department of Mechanical Engineering Faculty of EngineeringShizuoka University3-5-1 JohokuNaka-kuHamamatsu-shiShizuoka 432-8561Japan

Magnesium alloy is attractive for lightweight construction but often suffers from poor corrosion resistance and low *** processing with chemicals,i.e.,multifunction cavitation(MFC),was introduced to form a high-corrosion film and improve the fatigue properties of an AZ31 magnesium *** analysis and plane bending fatigue tests were conducted for the MFC-treated magnesium alloy at a stress ratio,R,*** mechanical action of cavitation bubbles improved the fatigue life of magnesium alloys due to increasing the surface hardness and generating compressive residual ***,the combined mechanical and electrochemical action during MFC formed pits on the *** pits were large enough to easily nucleate an initial fatigue *** addition,the magnesium alloys without pit formation,for which a coating process using phosphoric acid was conducted after MFC using water,showed superior fatigue properties.

关键词： Magnesium alloy Multifunction cavitation Surface modification Fatigue Residual stress

Fluorescence and Auger Decay Properties of the Core-Excited F-Like Ions from Ne to Kr

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Chinese Physics Letters 2012年第4期29卷 58-60页

作者： WANG Xiang-Li DONG Chen-Zhong SU Mao-Gen KOIKE fumihiro Key Laboratory of Atomic and Molecular Physics&Functional Materials of Gansu Province College of Physics and Electronic EngineeringNorthwest Normal UniversityLanzhou 730070 Physics Laboratory School of MedicineKitasato University1-15-1Kitasato 252-0374Japan

Ve systematically study the decay properties of the K-shell excited F-like ions with 10≤Z≤36 based on the multiconfiguration Dirac-Fock *** Breit interaction,the QED corrections and the nuclear finite mass effects are also considered as *** transition rates,radiative,Auger and natural widths,as well as fluorescence and Auger yields for K-shell excited F-like ions are *** is shown by means of concrete figures that the decay properties change significantly with the increase of the atomic number Z;the Auger rate is overtaken at Z =30 by the radiative decay *** fitting formulae for the radiative and Auger widths and the fluorescence yields have been evaluated which is expected to be useful in plasma analysis and plasma modeling.

关键词： perturbation method radiative

Dielectronic Recombination of Br-Like Tungsten Ions

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Plasma Science and Technology 2014年第3期16卷 182-187页

作者：李麦娟符彦飙苏茂根董晨钟 Koike fumihiro Key Laboratory of Atomic and Molecular Physics & Functional Material of Gansu Province College of Physics and Electronic EngineeringNorthwest Normal University Joint Laboratory of Atomic and Molecular Physics Northwest Normal University and Institute of Modern Physics of Chinese Academy of Sciences Atomic and Molecular Data Research Center National Institute for Fusion Science

Accurate data for dielectronic recombination of tungsten ions are essential in the modeling of tungsten impurity transport and radiative power loss in International Thermonuclear Experimental Reactor （ITER）. Theoretical calculations have been made for dielectronic recombi- nation （DR） rate coefficients of Br-like tungsten ions using a flexible relativistic atomic code （FAC） from i eV to 50 keV. Level-by-level calculations are carried out for evaluating the contributions to DR through all the relevant Kr-like tungsten ions autoionizing inner-shell excited configuration complexes：（3s23p63d10）-14s24p5nlntl＇（n = 4-5, n＇ = 4-100,l＇ = 0-8）, （4s24pS）-lnln＇l＇（n = 4-6, n＇ = 4-100, l＇ = 0-12）. Comparison of the rate coefficients for 3s, 3p, 3d, 4s and 4p subshell excitations shows that the 4p subshell excitation dominates over the whole temperature region, 4s subshell excitation at low temperature and 3p, 3d subshell excitations at high temperature can not be neglected. In order to facilitate simple applications, the total DR rate coefficient, △n = 0,1 and 2 core excitations DR rate coefficients are fitted to an empirical formula.

关键词： Br-like tungsten dielectronic recombination rate coefficients

Excitation and decay dynamics of 1s2s inner-shell double-vacancy states of neon atoms

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Chinese Physics B 2008年第2期17卷 592-598页

作者：丁晓彬董晨钟 fumihiro Koike Takako Kato Stephan Fritzsche College of Physics and Electronic Engineering Northwest Normal University Center of Theoretical Nuclear Physics National laboratory of Heavy-Ion Accelerator of Lanzhou Physics Department School of MedicineKitasato University1-15-1 Kitasato228-8555Japan National Institute for Fusion Science Department of Physics University of KasselHeinrich-Plett-Straβe 40D-34132KasselGermany

The photo-excitation and Auger decay processes of inner-shell double vacancy states 1s2s2p^6（1,3^S）3s3p of neutral neon atoms have been studied theoretically. Multi-configuration Dirac-Fock （MCDF） calculations have been carried out, with electron correlation effects taken into consideration. The relaxation of core and excited orbitals and configuration interaction are found to be crucial to creating the double vacancy states by single photo-absorption. The predominant decay paths for the double vacancy states turn out to be of the LLM Auger decay to 1s 2s^22p^53s（3p）, KLL Auger decay to 1s^22s2p^43s3p, and KLM Auger decay to 1s^22p^63s（3p）. They lead to further Auger decay, creating the neon ions of multiple charge states. For both double and single vacancy states the spectator type of Auger process is dominated in all the Auger decay processes. Theoretical Anger electron spectra are presented for further investigations, experimental and theoretical.

关键词： correlation effects multi-configuration Dirac-Fock (MCDF) method Auger decay

Hydriding properties of uranium alloys for purposes of searching for new hydrogen storage materials

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Nuclear Science and Techniques 2015年第1期26卷 121-126页

作者： Michio Yamawaki Takuya Yamamoto Yuji Arita fumihiro Nakamori Kazuhito Ohsawa Kenji Konashi Research Institute of Nuclear Engineering University of Fukui1-2-4 Kanawa-cho Tsuruga Fukui 914-0055 Japan Research Institute for Applied Mechanics Kyushu University6-1 Kasuga-koen Kasuga Fukuoka 816-8580 Japan Institute for Materials Research Tohoku University 2145-2 Narita-choOarai Higashi-Ibaragi-gun Ibaragi 311-1313 Japan

Hydriding properties of uranium alloys have been studied to search for new hydrogen storage materials to be applied to hydrogen energy systems. Application of uranium-base hydrogen storage materials can be expected to alleviate the risk, as well as to reduce the cost incurred by globally-stored large amounts of depleted uranium left after uranium enrichment. Various uranium alloys have been examined in terms of hydrogen absorptiondesorption properties, among which UNi Al intermetallic compound showed promising characteristics, such as lower absorption-desorption temperatures and better anti-powdering strength. First principle calculation has been carried out on UNi Al hydride to predict the change of crystal structure and the lattice constant with increasing hydrogen content, which showed this calculation to be promising in predicting candidates for good hydrogen absorbers.

关键词：氢化性能储氢材料铀合金第一原理计算金属间化合物能源系统解吸温度晶格常数

KLL dielectronic recombination process of He-like to O-like xenon ions

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Chinese Physics B 2012年第1期21卷 163-170页

作者： Zhang Deng-Hong Shi Ying-Long Jiang Jun Dong Chen-zhong fumihiro Koike Key Laboratory of Atomic and Molecular Physics&Functional Materials of Gansu Province College of Physics and Electronic EngineeringNorthwest Normal UniversityLanzhou 730070China Joint Laboratory of Atomic and Molecular Physics NWNU&IMP CASLanzhou 730070China Physics Department School of MedicineKitasato University1-15-1 Kitasato228-8555Japan

In this work, the KLL dielectronic recombination （DR） processes of highly charged He-like to O-like xenon ions are studied systematically by using a DR program, which is based on the multi-configuration Dirac-Fock （MCDF） method. The KLL DR resonant energies and the corresponding resonant strengths are calculated, emphasizing especially the effect of the Breit interaction on the DR strengths. The theoretical KLL DR spectra are obtained and compared with the latest experimental results obtained in the Shanghai Electron Beam Ion Trap.

关键词： KLL dielectronic recombination resonant strength Breit interaction