Microglia have multiple functions and phenotypes that can prevent or worsen *** depletion and repopulation methods provide a promising technique for understanding microglial *** utility as therapeutic modalities is no...
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Microglia have multiple functions and phenotypes that can prevent or worsen *** depletion and repopulation methods provide a promising technique for understanding microglial *** utility as therapeutic modalities is now under *** resident immune cells in the central nervous system(CNS),microglia maintain the local environment and promote neuronal ***,persistent proinflammatory signaling due to aberrant microglial activation can be *** is seen in settings such as traumatic brain injury(tBI)(Henry et al.,2020),stroke(Li et al.,2017),and alcohol use disorder(AUD)(Coleman et al.,2020),when the loss of homeostatic control results in persistent proinflammatory signaling that contributes to ongoing neuropathology(Figure 1).thus,selective replacement of chronically proinflammatory-activated microglia could improve functional outcomes.
<正>During the last five years new understanding has emerged on the chemical biology of fungi(Ascomycota)within the genus Aspergillus,considered by many as the model organism for eurkaryotic biology ***,a rare fun...
<正>During the last five years new understanding has emerged on the chemical biology of fungi(Ascomycota)within the genus Aspergillus,considered by many as the model organism for eurkaryotic biology ***,a rare fungal species,
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