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Identification and effective regulation of scarb1 gene involved in pigmentation change in autotetraploid Carassius auratus

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Zoological Research 2024年第2期45卷 381-397页

作者： Xi-Dan Xu Yue Zhou Chong-Qing Wang Xu Huang Kun Zhang xiao-Wei Xu Li-Wen He Xin-Yue Zhang Xin-Zhu fu Ming Ma Qin-Bo Qin Shao-Jun Liu State Key Laboratory of Developmental Biology of Freshwater Fish Engineering Research Center of Polyploid Fish Reproduction and Breeding of the State Education MinistryCollege of Life SciencesHunan Normal UniversityChangshaHunan 410081China Nansha-South China Agricultural University Fishery Research Institute GuangzhouGuangdong 511458China Hunan Yuelu Mountain Science and Technology Co.Ltd.for Aquatic Breeding ChangshaHunan 410081China College of Chemistry and Chemical Engineering Hunan Normal UniversityChangshaHunan 410081China

The autotetraploid Carassius auratus(4nRR,4n=200,RRRR)is derived from whole-genome duplication of Carassius auratus red var.(RCC,2n=100,RR).In the current study,we demonstrated that chromatophores and pigment changes directly caused the coloration and variation of 4nRR skin(red in RCC,brownish-yellow in4nRR).To further explore the molecular mechanisms underlying coloration formation and variation in 4nRR,we performed transcriptome profiling and molecular functional verification in RCC and *** revealed that scarb1,associated with carotenoid metabolism,underwent significant down-regulation in *** editing of this candidate pigment gene provided clear evidence of its significant role in RCC ***,we identified four divergent scarb1 homeologs in 4nRR:two original scarb1 homeologs from RCC and two duplicated ***,three of these homeologs possessed two highly conserved alleles,exhibiting biased and allelespecific expression in the ***,after precise editing of both the original and duplicated scarb1homeologs and/or alleles,4nRR individuals,whether singly or multiply mutated,displayed a transition from brownishyellow skin to a cyan-gray ***,the proportional areas of the cyan-gray regions displayed a gene-dose *** findings illustrate the subfunctionalization of duplicated scarb1,with all scarb1genes synergistically and equally contributing to the pigmentation of *** is the first report concerning the functional differentiation of duplicated homeologs in an autopolyploidfish,substantiallyenrichingour understanding of coloration formation and change within this group of organisms.

关键词： Autopolyploidization Coloration change scarb1 functional differentiation Genetic changes

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Earth-abundant Zn-dipyrrin chromophores for efficient CO2 photoreduction

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National Science Review 2024年第06期 214-222页

作者： Song Guo fu-Gui Zeng xiao-Di Li Kai-Kai Chen Ping Wang Tong-Bu Lu Zhi-Ming Zhang Institute for New Energy Materials and Low Carbon Technologies School of Materials Science& Engineering Tianjin University of Technology

The development of strong sensitizing and Earth-abundant antenna molecules is highly desirable for CO2reduction through artificial photosynthesis. Herein, a library of Zn–dipyrrin complexes（Z-1-Z-6） are rationally designed via precisely controlling their molecular configuration to optimize strong sensitizing Earth-abundant photosensitizers. Upon visible-light excitation, their special geometry enables intramolecular charge transfer to induce a charge-transfer state, which was first demonstrated to accept electrons from electron donors. The resulting long-lived reduced photosensitizer was confirmed to trigger consecutive intermolecular electron transfers for boosting CO2-to-CO conversion. Remarkably, the Earth-abundant catalytic system with Z-6 and Fe-catalyst exhibits outstanding performance with a turnover number of >20 000 and 29.7% quantum yield, representing excellent catalytic performance among the molecular catalytic systems and highly superior to that of noble-metal photosensitizer Ir（ppy）2（bpy）+under similar conditions. Experimental and theoretical investigations comprehensively unveil the structure–activity relationship, opening up a new horizon for the development of Earth-abundant strong sensitizing chromophores for boosting artificial photosynthesis.

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不确定离散半马尔可夫跳变系统的有限时间鲁棒H_(∞)控制

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控制与决策 2024年第3期39卷 836-844页

作者：郑柏浩嵇小辅朱毅江南大学物联网工程学院江苏无锡214122 江南大学轻工过程先进控制教育部重点实验室江苏无锡214122

研究一类不确定离散时间半马尔可夫跳变系统的有限时间鲁棒H_(∞)控制问题.首先,应用半马尔可夫核方法建模离散时间系统的半马尔可夫跳变过程,其中驻留时间的概率密度函数依赖系统当前模态和下一模态,使得所提出理论可考虑不同的驻留时... 详细信息

研究一类不确定离散时间半马尔可夫跳变系统的有限时间鲁棒H_(∞)控制问题.首先,应用半马尔可夫核方法建模离散时间系统的半马尔可夫跳变过程,其中驻留时间的概率密度函数依赖系统当前模态和下一模态,使得所提出理论可考虑不同的驻留时间概率分布类型,针对随机跳变系统有限时间分析中的跳变次数问题,提出估计跳变次数最大值的方法;然后,考虑系统模态驻留时间的上下界,提出新的有限时间有界概念,并保证基于半马尔可夫核方法给出的不确定离散时间半马尔可夫随机跳变系统有限时间有界判据数值可解;接着,在此基础上,分析系统的H_(∞)性能指标,设计模态依赖的状态反馈控制律保证闭环系统的有限时间鲁棒H_(∞)性能;最后,通过2个算例仿真验证所提出理论的可行性和有效性.

关键词：离散时间系统半马尔可夫跳变系统有限时间有界鲁棒H_(∞)控制半马尔可夫核线性矩阵不等式

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Graphite recycling from spent lithium-ion batteries for fabrication of high-performance aluminum-ion batteries

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Rare Metals 2024年第5期43卷 2161-2171页

作者： Li Wang Chao Wang Jing-Yi Zhang Jia-Cheng Qiu Xu-Wang fu Zi-Rui Zhang Jian-Min Feng Lei Dong Cong-Lai Long De-Jun Li xiao-Wei Wang Bao Zhang Jia-Feng Zhang Rui-Rui Zhao College of Physics and Materials Science Tianjin Normal UniversityTianjin300387China National Engineering Laboratory for High Efficiency Recovery of Refractory Nonferrous Metals School of Metallurgy and EnvironmentCentral South UniversityChangsha 410083China School of Chemistry South China Normal UniversityGuangzhou510631China

Efficient extraction of electrode components from recycled lithium-ion batteries(LIBs)and their highvalue applications are critical for the sustainable and ecofriendly utilization of *** work demonstrates a novel approach to stripping graphite anodes embedded with Li^(+)from spent LIBs directly in anhydrous ethanol which can be utilized as high efficiency cathodes for aluminum-ion batteries(AIBs).Recycled graphite(RG)with foam morphology and crystal structure defects was obtained under the action of ultrasonic peeling and gas generation reaction between residual lithium-graphite interlayer compound and *** inherent open structure of RG facilitates the intercalation/deintercalation of chloralum anions(AlCl_(4)^(-))and enhances its AIB cathode *** electrochemical measurements revea that the RG cathode has a specific capacity of 123 m Ah·g^(-1)at a current of 5 A·g^(-1),which is 1.55 times higher than tha of unprocessed natural graphite and 1.25 times higher than that of commercial artificial ***,the RG cathode demonstrated remarkable stability,retaining its high particular capacity of 138.15 mAh·g^(-1)even through2000 times at 10 A·g^(-1)in a low-cost electrolyte consisting of an ionic liquid/urea/AlCl_(3)*** work offers a novel approach to reusing of graphite anode waste materials from LIBs.

关键词： Aluminum ion batteries Lithium-ion batteries Graphite anode Recycling

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Gut microbial metabolite targets HDAC3-FOXK1-interferon axis in fibroblast-like synoviocytes to ameliorate rheumatoid arthritis

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Bone Research 2024年第2期12卷 421-437页

作者： Hongzhen Chen Xuekun fu xiaohao Wu Junyi Zhao Fang Qiu Zhenghong Wang Zhuqian Wang Xinxin Chen Duoli Xie Jie Huang Junyu Fan Xu Yang Yi Song Jie Li Dongyi He Guozhi xiao Aiping Lu Chao Liang Department of Systems Biology School of Life SciencesSouthern University of Science and TechnologyGuangdong Provincial Key Laboratory of Cell Microenvironment and Disease ResearchShenzhen Key Laboratory of Cell MicroenvironmentShenzhen 518055China Institute of Integrated Bioinfomedicine and Translational Science(IBTS) School of Chinese MedicineHong Kong Baptist UniversityHong Kong SAR 999077China Department of Biochemistry School of MedicineSouthern University of Science and TechnologyGuangdong Provincial Key Laboratory of Cell Microenvironment and Disease ResearchShenzhen Key Laboratory of Cell MicroenvironmentShenzhen 518055China Division of Immunology and Rheumatology Stanford UniversityStanfordCA 94305USA VA Palo Alto Health Care System Palo AltoCA 94304USA Institute of Plant and Food Science Department of BiologySouthern University of Science and TechnologyShenzhen 518055China Department of Rheumatology Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai University of Traditional Chinese MedicineShanghaiChina Department of Computational Biology St.Jude Children’s Research HospitalMemphisTNUSA Department of Laboratory Medicine Peking University Shenzhen HospitalShenzhenChina Guangdong-Hong Kong-Macao Joint Lab on Chinese Medicine and Immune Disease Research Guangzhou 510006China Shanghai University of Traditional Chinese Medicine Shanghai 200032China State Key Laboratory of Proteomics National Center for Protein Sciences(Beijing)Beijing Institute of Lifeomics100850 BeijingChina

Rheumatoid arthritis(RA)is an autoimmune *** studies hold an opinion that gut microbiota is environmentally acquired and associated with RA ***,accumulating evidence demonstrates that genetics also shape the gut *** is known that some strains of inbred laboratory mice are highly susceptible to collagen-induced arthritis(CIA),while the others are resistant to ***,we show that transplantation of fecal microbiota of CIA-resistant C57BL/6J mice to CIA-susceptible DBA/1J mice confer CIA resistance in DBA/1J mice.C57BL/6J mice and healthy human individuals have enriched *** than DBA/1J mice and RA *** of *** prevents CIA in DBA/1J *** identify that *** mainly produces propionate and C57BL/6J mice and healthy human individuals have higher level of ***-like synoviocytes(FLSs)in RA are activated to undergo tumor-like *** disrupts HDAC3-FOXK1 interaction to increase acetylation of FOXK1,resulting in reduced FOXK1 stability,blocked interferon signaling and deactivation of *** treat CIA mice with propionate and show that propionate attenuates ***,a combination of propionate with anti-TNF etanercept synergistically relieves *** results suggest that *** or propionate could be an alternative or complementary approach to the current therapies.

关键词： HDAC3 cytes interferon

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焦虑对雌性成年斑马鱼热耐受和游泳能力的影响

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水生生物学报 2024年第9期48卷 1566-1572页

作者：李小红付成付世建重庆师范大学进化生理与行为学实验室淡水鱼类资源保护与利用重庆市重点实验室重庆401331

为研究焦虑对鱼类热耐受和游泳能力的影响,以雌性成年斑马鱼(Danio rerio)为研究对象,将实验鱼随机分为焦虑组和对照组,焦虑组通过2周慢性不可预测应激(Unpredictable chronic stress, UCS)处理建立焦虑斑马鱼模型,对照组不做任何处理。... 详细信息

为研究焦虑对鱼类热耐受和游泳能力的影响,以雌性成年斑马鱼(Danio rerio)为研究对象,将实验鱼随机分为焦虑组和对照组,焦虑组通过2周慢性不可预测应激(Unpredictable chronic stress, UCS)处理建立焦虑斑马鱼模型,对照组不做任何处理。2周后测定两组实验鱼的焦虑行为相关指标、全身皮质醇及雌二醇水平,热耐受[临界高温(CT_(max))、临界低温(CT_(min))、致死高温(LT_(max))和致死低温(LT_(min))]及游泳能力(最大匀加速游泳速度, Ucat)。结果显示:焦虑组实验鱼的焦虑水平、皮质醇水平显著高于对照组(P0.05)。研究表明:2周UCS处理能建立焦虑斑马鱼模型,焦虑引起的雌性成年斑马鱼雌激素分泌减少可能对斑马鱼后期的繁殖产生消极影响;另外,焦虑降低了斑马鱼的低温耐受能力,可能与皮质醇水平升高和焦虑导致的体质下降有关。

关键词：焦虑热耐受最大匀加速游泳速度慢性不可预测应激斑马鱼

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Cervical myeloid sarcoma as an initial clinical manifestation: Four case reports

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World Journal of Clinical Oncology 2024年第10期15卷 1324-1332页

作者： Jin-Ke Li xiao-Xue Wang Jia-Jun fu Dan-Dan Zhang Department of Obstetrics and Gynecology Shengjing Hospital of China Medical UniversityShenyang 110004Liaoning ProvinceChina Department of Health Management Shengjing Hospital of China Medical UniversityShenyang 110004Liaoning ProvinceChina Department of Pathology Shengjing Hospital of China Medical UniversityShenyang 110004Liaoning ProvinceChina

BACKGROUND Cervical myeloid sarcoma(MS)is a rare hematological malignancy characterized by the formation of extramedullary soft tissue masses in the cervical *** to its uncommon presentation in the female reproductive system,cervical MS poses significant diagnostic and therapeutic ***,there is a pressing need for more research and clinical experience to better understand,diagnose,and manage this condition *** SUMMARY This report details four cases,the diagnostic process,treatment strategy,and outcomes,discussing cervical MS as an initial clinical *** disease exhibits varied clinical presentations,such as irregular vaginal bleeding and pa-lpation of cervical *** treatment approaches discussed include neoad-juvant chemotherapy,surgery,and postoperative chemotherapy,though mana-ging the disease remains *** report also features a comprehensive literature review that underscores the importance of immunohistochemistry for accurate diagnosis,identifying key markers,including myeloperoxidase,cluster of differentiation(CD)68,and CD43,stressing the need for further research to improve treatment strategies and *** Immunohistochemical diagnosis and tailored therapeutic strategies are *** research is crucial in improving outcomes and developing effective treatment protocols.

关键词： Cervical myeloid sarcoma Hematologic malignancy Clinical characteristics Diagnosis Treatment Case report

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Laves-Co_(2)(HfTa)合金的相稳定性及热物性

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物理学报 2024年第12期73卷 277-287页

作者：丁宁倪晓东田付阳北京科技大学应用物理研究所北京100083

基于第一性原理计算方法,在考虑磁效应的基础上,对不同温度下合金Co_(2)(HfTa)中的稳定结构、电子性质和热力学性质展开了研究.通过第一性原理计算形成能、弹性性质及声子色散关系,结果表明合金Co_(2)(Hf_(x)Ta_(1-x))在x≤0.75时基态是... 详细信息

基于第一性原理计算方法,在考虑磁效应的基础上,对不同温度下合金Co_(2)(HfTa)中的稳定结构、电子性质和热力学性质展开了研究.通过第一性原理计算形成能、弹性性质及声子色散关系,结果表明合金Co_(2)(Hf_(x)Ta_(1-x))在x≤0.75时基态是C36,当x>0.75时基态是C14.这一发现提示了合金成分对其基态结构的影响,并为合金的稳定性提供了重要线索.值得注意的是,考虑了振动熵和电子熵的贡献后,Co_(2)Hf相对稳定的结构变为C36,Co_(2)Ta变为C14,这表明温度会对合金结构稳定性的影响.Co_(2)(Hf_(x)Ta_(1-x))合金在弹性方面呈现出本征脆性.热力学分析表明其在高温下热容趋于稳定,德拜温度近似为常数,振动熵随温度递增且与压强负相关.电子态密度分析揭示了Co_(2)(HfTa)合金三个结构的相稳定性.

关键词： Co_(2)(HfTa) Laves相稳定性热物性质第一性原理计算

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A shape-reconfigurable,light and magnetic dual-responsive shape-memory micropillar array chip for droplet manipulation

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Chinese Chemical Letters 2024年第1期35卷 456-460页

作者： Wen-Qi Ye Wen-Xin fu xiao-Peng Liu Chun-Guang Yang Zhang-Run Xu Research Center for Analytical Sciences Northeastern UniversityShenyang 110819China

Droplet manipulation on an open surface has great potential in chemical analysis and biomedicine ***,most of the reported platforms designed for the manipulation of water droplets cannot thoroughly solve the problem of droplet ***,we report a shape-reconfigurable micropillar array chip for the manipulation of water droplets,oil droplets and water-in-oil ***-in-oil droplets provide an enclosed space for water droplets,preventing the evaporation in an open *** coated on the surface of the chip effectively reduces the droplet movement *** micropillar array chip has light and magnetic dual-response due to the Fe3O4 nanoparticles and the reduced iron powder mixed in the shape-memory *** micropillars irradiated by a near-infrared laser bend under the magnetic force,while the unirradiated micropillars still keep their original *** the absence of a magnetic field,when the micropillars in a temporary shape are irradiated by the near-infrared laser to the transition temperature,the micropillars return to their initial *** this process,the surface morphology gradient caused by the deformation of the micropillars and the surface tension gradient caused by the temperature change jointly produce the driving force of droplet movement.

关键词： Microfluidics Droplet manipulation Micropillar array Shape memory polymer Magnetic response Light response

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数据要素流通中的档案分级分类管理:理论内涵、实践困境与优化路径

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山西档案 2024年第5期 39-42页

作者：付虓北京石油化工学院北京102617

数据要素流通正深刻改变着档案管理环境,推动着档案分级分类管理加速变革创新。数据要素流通是数字经济时代的显著特征,对档案分级分类管理提出全新的要求。纵观档案分级分类管理的理论研究和实践现状,传统分类方法的静态封闭属性与数... 详细信息

数据要素流通正深刻改变着档案管理环境,推动着档案分级分类管理加速变革创新。数据要素流通是数字经济时代的显著特征,对档案分级分类管理提出全新的要求。纵观档案分级分类管理的理论研究和实践现状,传统分类方法的静态封闭属性与数据环境的开放动态特征之间存在矛盾,现有标准规范体系建设滞后于档案管理发展需求,档案分级分类智能化改造的力度、广度、深度不足等,都是制约其创新发展的突出问题。数字时代背景下,破解档案分级分类管理困境,需要坚持问题导向、目标导向,树立与时俱进的管理理念,加快法治化、标准化建设进程,强化人工智能、大数据等现代技术赋能,切实提升档案管理人员的数字素养,着力构建内容导向、需求导向的分类理论体系,优化资源共享开放机制,为档案资源的规范化、精细化、智能化管理和高效配置提供坚实支撑。

关键词：数据要素档案分级分类理论内涵实践困境

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