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On the Bump Tests of Cracked Shafts Using Acoustic Emission Techniques

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Engineering（科研） 2016年第9期8卷 572-581页

作者： Gilberto Luiz S. Pimentel-Junior frederico B. oliveira Marco Tulio C. Faria Department of Mechanical Engineering Universidade Federal de Minas Gerais Belo Horizonte Brazil

An investigation about the application of Acoustic Emission (AE) techniques to analyze the dynamic response of different cracked shafts rendered in bump tests is presented in this work. The experimental apparatus devised for this work complies of six shafts with different transverse crack sizes and a high-frequency data acquisition system. The AE signals generated in the bump tests performed on the different cracked shafts are captured by a wideband AE transducer. Those signals are treated by using statistical moments, wavelet transforms, and frequency- and time-domain procedures. A transverse crack of predetermined depth is etched into each shaft. The experimental results show that the values of kurtosis and skewness estimated for the AE signals can be used to identify the crack size.

关键词： Acoustic Emission Cracked Rotors Bump Tests Shaft Crack

Adaptive Thermal Comfort in Brazilian Schools by Building Performance Simulation (BPS)

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Journal of Civil Engineering and Architecture 2020年第3期14卷 174-178页

作者： Caio frederico e Silva Adriano Felipe oliveira Lopes Thiago Montenegro Góes Cláudia Naves David Amorim University of Brasília Brasilia 70910-900Brazil

Building performance simulation (BPS) is a crucial tool towards the design of projects better adapted its climatic context. In this sense, the objective of this research is to evaluate a method of thermal comfort analysis of schools in three Brazilian cities using BPS. The methodological procedures involved a literature review, in which the simulation tool and analysis method were chosen. Following simulations with the software DesignBuilder were performed using as study case a standard school typology designed by the General Coordination of Educational Infrastructure (CODIN/FNDE). This article evaluates its percentage occupied comfort hours in 3 reference cities: Cuiabá-MT, Brasília-DF, and Curitiba-PR. The results show respectively, for the cities of Curitiba, Brasília and Cuiabá, percentages of comfort hours of 76%, 70%, and 23%. The research states that the project must have different strategies for different climates. Finally, this article recommends this method should be applied to other cities and buildings.

关键词： Building performance simulation thermal comfort standard design protocol schools.

Can gadoxetic acid–enhanced magnetic resonance imaging be used to avoid liver biopsy in patients with nonalcoholic fatty liver disease?

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World Journal of Hepatology 2020年第9期12卷 661-671页

作者： Viviane Brandão Amorim Daniella Braz Parente Fernando Fernandes Paiva Jaime Araújo oliveira Neto Amanda Almeida Miranda Cláudia Cravo Moreira Flávia Ferreira Fernandes Carlos frederico FerreiraCampos Nathalie Carvalho Leite Renata de Mello Perez Rosana Souza Rodrigues Research Department D’Or Institute for Research and EducationRio de Janeiro 22281Brazil Radiology Department Brazilian National Cancer InstituteRio de Janeiro 20230-130Brazil Radiology Department Fleury Group S.A.Rio de Janeiro 20765-000Brazil Radiology Department Hospital Universitário Clementino Fraga FilhoFederal University of Rio de JaneiroRio de Janeiro 21941-590Brazil São Carlos Institute of Physics University of São PauloSão Carlos 13560-970Brazil Radiology Department Quinta D'Or HospitalRio de Janeiro 20941-150Brazil Radiology Department Centro de Diagnóstico Médico do MaranhãoMaranhão 65074-441Brazil Department of Clinical Medicine Hospital Universitário Clementino Fraga FilhoFederal University of Rio de JaneiroRio de Janeiro 21941-590Brazil Gastroenterology and Hepatology Department Hospital Federal de BonsucessoRio de Janeiro 21041-030Brazil Department of Pathology and Laboratories University of the State of Rio de JaneiroRio de Janeiro 20551-030Brazil Internal Medicine Department Hospital Universitário Clementino Fraga FilhoFederal University of Rio de JaneiroRio de Janeiro 21941-590Brazil Gastroenterology Department Hospital Universitário Pedro ErnestoUniversity of the State of Rio de JaneiroRio de Janeiro 20551-030Brazil

BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is a major cause of liver disease *** diagnosis of nonalcoholic steatohepatitis(NASH),the most severe form of NAFLD,is crucial and has prognostic and therapeutic ***,currently this diagnosis is based on liver biopsy and has several *** To evaluate the performance of gadoxetic acid–enhanced magnetic resonance imaging(GA-MRI)in differentiating isolated steatosis from NASH in patients with *** In this prospective study,56 patients with NAFLD(18 with isolated steatosis and 38 with NASH)underwent *** contrast enhancement index(CEI)was calculated as the rate of increase of the liver-to-muscle signal intensity ratio from before and 20 min after intravenous GA ***-group differences in mean CEI were examined using Student's t *** area under the receiver operator characteristic curve and the diagnostic performance of gadoxetic acid–enhanced magnetic resonance imaging were *** The mean CEI for all subjects was 1.82±*** mean CEI was significantly lower in patients with NASH than in those with isolated steatosis(P=0.008).Two CEI cut-off points were used:2.00(89%sensitivity)to characterize isolated *** values between 1.66 and 2.00 indicated liver biopsy,and the procedure could be avoided in 40%of patients with *** GA-MRI is an effective noninvasive method that may be useful for the differentiation of NASH from isolated steatosis,and could help to avoid liver biopsy in patients with NAFLD.

关键词： Fatty liver Nonalcoholic fatty liver disease Nonalcoholic steatohepatitis Gadoxetic

Productivity and Dry Matter Accumulation of Sugarcane Crop under Irrigation and Nitrogen Application at Rio Verde GO, Brazil

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American Journal of Plant Sciences 2015年第14期6卷 2374-2384页

作者： Alefe Viana Souza Bastos Renato Campos de oliveira Nelmício Furtado da Silva Marconi Batista Teixeira frederico Antonio Loureiro Soares Edson Cabral da Silva Instituto Federal Goiano (IFgoiano) Rio Verde Brazil

Dry matter production and productivity of stem currently are being widely studied in sugarcane, reinforcing the study in question, which aims to assess the accumulation of dry matter of the aerial segment and the productivity of stems of sugarcane crops within the first cycle, at different levels of water replacement (WR) with and without nitrogen fertilization, through a subsurface drip irrigation system. The assay was conducted in the experimental area of the Federal Institut Goiano, Campus Rio Verde, GO, Brazil, in a dystroferric Rhodic Hapludox soil, cerrado phase (savannah), and comprised experimental splits of three furrows with an 8-meter long double row. Experimental design consisted of randomized blocks in a 5 × 2 factorial array, with four replications. Evaluated factors comprised five levels of WR (100%, 75%, 50%, 25% and 0% of field capacity), with and without the application of nitrogen (0 and 100 kg·ha-1 urea). Harvest occurred in May 2013 and stem productivity (SP), productivity of pointers (PP), productivity of straw (PS), harvest index (HI), dry matter of stem (DMS), dry matter of pointers (DMP), the relationship between dry matter of pointer and dry matter of stem (DMP/DMS) and total dry matter of the aerial segment (TDM) were determined. The variables SP, PP, DMS and DMP had a linear growth in proportion to WR increase, whereas HI and DMP/DMS adjusted to a quadratic model. Nitrogen fertilization affected positively the variables SP, HI, DMS and DMP/DMS and occurred interaction to TDM;also increasing the productivity stem and the harvest index.

关键词： Sugarcane Ratoon Water Replacement Nitrogen Fertilizer

Changes in cellular proliferation and plasma products are associated with liver failure

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World Journal of Hepatology 2016年第32期8卷 1370-1383页

作者： Juliana Gil Melgaco frederico Marianetti Soriani Pedro Henrique Ferreira Sucupira Leonardo Assaf Pinheiro Yasmine Rangel Vieira Jaqueline Mendes de oliveira Lia Laura Lewis-Ximenez Cristina Carvalho Vianna Araújo Lúcio Filgueiras Pacheco-Moreira Gustavo Batista Menezes Oswaldo Goncalves Cruz Claudia Lamarca Vitral Marcelo Alves Pinto Departamento de Microbiologia e Parasitologia Universidade Federal Fluminense Instituto Oswaldo Cruz/Fiocruz Laboratório de Desenvolvimento Tecnológico em Virologia Departamento de Biologia Geral Instituto de Ciencias BiologicasUniversidade Federal de Minas Gerais Instituto Oswaldo Cruz/Fiocruz Ambulatório de Hepatites Virais Hospital Federal de Bonsucesso Laboratório de Imunofarmacologia Departamento de Bioquímica e ImunologiaInstituto de Ciencias BiológicasUniversidade Federal de Minas Gerais Fundacao Oswaldo Cruz Programa de Computacao Científica

AIM To study the differences in immune response and cytokine profile between acute liver failure and selflimited acute *** Forty-six patients with self-limited acute hepatitis(AH), sixteen patients with acute liver failure(ALF), and twenty-two healthy subjects were involved in this study. The inflammatory and anti-inflammatory products in plasma samples were quantified using commercial enzyme-linked immunoassays and quantitative real-time PCR. The cellular immune responses were measured by proliferation assay using flow cytometry. The groups were divided into viral- and non-viral-induced selflimited AH and ALF. Thus, we worked with five groups: Hepatitis A virus(HAV)-induced self-limited acute hepatitis(HAV-AH), HAV-induced ALF(HAV-ALF), nonviral-induced self-limited acute hepatitis(non-viral AH), non-viral-induced acute liver failure(non-viral ALF), and healthy subjects(HC). Comparisons among HAV and non-viral-induced AH and ALF were *** The levels of mitochondrial DNA(mt DNA) and the cytokines investigated [interleukin(IL)-6, IL-8, IL-10, interferon gamma, and tumor necrosis factor] were significantly increased in ALF patients, independently of etiology(P < 0.05). High plasma mt DNA and IL-10 were the best markers associated with ALF [mt DNA: OR = 320.5(95%CI: 14.42-7123.33), P < 0.0001; and IL-10: OR = 18.8(95%CI: 1.38-257.94), P = 0.028] and death [mt DNA: OR = 12.1(95%CI: 2.57-57.07), P = 0.002; and IL-10: OR = 8.01(95%CI: 1.26-50.97), P = 0.027]. In the cellular proliferation assay, NK^(bright), NKT and regulatory T cells(TReg) predominated in virusspecific stimulation in HAV-induced ALF patients with an anergic behavior in the cellular response to mitotic stimulation. Therefore, in non-viral-induced ALF, anergic behavior of activated T cells was not observed after mitotic stimulation, as expected and as described by the literature. CONCLUSION mt DNA and IL-10 may be predictors of ALF and death. TReg cells are involved in immunologi

关键词： Acute liver failure Cytokines Mitochondrial DNA Cellular immune response Hepatitis A virus

Clinical Assessment of the Use of Propinox Hydrochloride and Scopolamine Hydrochloride in the Treatment of Abdominal Colic: A Retrospective, Comparative Study

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International Journal of Clinical Medicine 2016年第7期7卷 474-480页

作者： Helio Rzetelna Carlos frederico Porto Alegre Rosa Mario Kirzner Lucas Pereira Jorge de Medeiros Camila Melo Marcia Gonçalves Ribeiro Lisa oliveira José Galvão Alves Mauro Geller Gastroenterology Department Universidade Federal do Rio de Janeiro (UFRJ) Rio de Janeiro Brazil Clinical Medicine Department Centro Universitário Volta Redonda (UNIFOA) Volta Redonda Brazil Clinical Medicine and Gastroenterology Department Universidade Estácio de Sá (UNESA) Rio de Janeiro Brazil Clinical Medicine Department Escola de Medicina Souza Marques Rio de Janeiro Brazil 5Inflammatory Bowel Diseases Outpatient Unit-18 ª enfermaria da Santa Casa da Misericórdia do Rio de Janeiro Rio de Janeiro Brazil Federação Brasileira de Gastroenterologia S&atildeo Paulo Brazil Grupo de Estudos de Doenças Inflamatórias Intestinais Rio de Janeiro Brazil UNESA Rio de Janeiro Brazil Gastroenterology Post-Graduation Program-PUC-Rio Rio de Janeiro Brazil Neurology Post-Graduation Program Universidade Federal do Estado do Rio de Janeiro (UERJ) Rio de Janeiro Brazil Pharmacology Department—UFRJ Rio de Janeiro Brazil Medical Genetics Service IPPMG-Universidade Federal Rio de Janeiro Rio de Janeiro Brazil Immunology Department Teresópolis Medical School (UNIFESO) Teresópolis Brazil Clinical Immunology Instituto de Pós-Gradua&ccedil&atildeo Médica Carlos Chagas (IPGMCC) Rio de Janeiro Brazil

Objectives: The purpose of this study was to evaluate and compare the use of propinox hydrochloride and scopolamine hydrochloride in patients presenting abdominal colic (abdominal pain), in terms of treatment efficacy and tolerability. Material & Methods: This was an analytical, retrospective, comparative study based on hospital records of outpatients treated at Serviço de Clínica Médica do Hospital das Clínicas Costantino Otaviano (HCTCO) and at Santa Casa de Misericórdia do Rio de Janeiro, from 1988-1998. Subjects were divided into two groups: patients from Group 1 were treated with propinox hydrochloride, while patients from Group 2 were treated with scopolamine hydrochloride. Statistical analysis was performed using GraphPad Prism version 5.0. For comparison of categorical variables, we used the chi-squared or Fisher’s test, while continuous variables were analyzed using ANOVA or the Student’s T test. Results: A total of 1042 subjects were included, of which 525 were allocated to Group 1 and 517 to Group 2. Mean treatment duration was 9.166 days (±4.208) in Group 1 and 8.795 days (±5.052) in Group 2, with no statistically significant difference in treatment duration between the two groups (p = 0.198). All subjects in Group 1 were treated with propinox 10 mg (2 coated tablets, three times per day) while all subjects in Group 2 were treated with scopolamine hydrochloride 10 mg (2 coated tablets, three times per day). There were no statistically significant between-group differences in weight, BMI, heart rate, and respiratory rate at pre- and post-treatment;with the exception of higher post-treatment systolic blood pressure in Group 1, blood pressure measures also remained homogenous. Adverse events were reported among both treatment groups with no significant between-group difference in incidence (p = 0566). At pretreatment, pain intensity was more severe in Group 1 (p = 0.0257), while at post-treatment, there was no statistically significant difference betw

关键词： Abdominal Colic Propinox Hydrochloride Scopolamine Hydrochloride

Effects of Mirror Therapy on the Lower Limb Functionality Hemiparesis after Stroke

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Health 2016年第14期8卷 1442-1452页

作者： Bruno Vieira Cortez Constância Karyne da Silva Coêlho Danylo Rafhael Costa Silva Maria da Conceição Barros oliveira Giselle Borges Vieira Pires de oliveira Francisco Mayron de Sousa e Silva Éric Heleno Freire Ferreira frederico Danúbia da Cunha de Sá-Caputo Mario Bernardo-Filho Janaína de Moraes Silva Departamento de Fisioterapia Faculdade Maurício de Nassau Teresina Brasil Pós-graduaç ã o da Rede Nordeste de Biotecnologia da Universidade Federal do Piauí Universidade Federal do Piauí Teresina Brasil Departamento de Fisioterapia Universidade Estadual do Piauí Teresina Brasil Laboratório de Vibracoes Mecanicas e Práticas Integrativas e Complementares Universidade do Estado do Rio de Janeiro Rio de Janeiro Brasil

Introduction: Mental exercise using the mirror therapy (MT) improves the retention of newly acquired skills and the performance of sequential motor skills in subjects with post-stroke hemiparesis. Objectives: The study aimed to analyze the mirror therapy effect on the range of motion and the lower limb functionality in post-stroke hemiparesis subjects. Materials and Methods: Eleven participants with hemiparesis in the lower limb were subjected to the 10 sessions of a MT protocol. The interventions were three times per week per 30 minutes each day. Evaluation of active and passive ankle goniometry (dorsiflexion and eversion movements);Ascent and Descent Ladder Rate (ADLR);Time Up and Go test (TUG test);EFEI scale;and FAAM scale were performed. The data were collected before and after the intervention using MT, and then statistically compared. Results: The MT improved significantly (p < 0.01) the range of motion of the paretic lower limb both evaluated by active and passive ankle goniometry. An increase in the speed of gait and other functional tasks related to the paretic lower limbs were found through the TUG and ADLR tests. It also demonstrated a positive influence on the functionality of the paretic lower limb motor control through the analysis of the scores in the FAAM and EFEI scales. Conclusion: It is concluded that the MT therapy can help the patients with post-stroke hemiparesis in the improvement of several functions. Probably, the mirror therapy would aid in the repair of the injuries in the cortical areas.

关键词： Mirror Therapy Stroke Hemiparesis Visual Feedback Functionality

The Development of Mathematical Modelling Activities from Thematic Projects in the Social-Critical Perspective

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Journal of Mathematics and System Science 2012年第6期2卷 341-347页

作者： Regina Helena de oliveira Lino Franchi frederico da Silva Reis Department of Mathematics Federal University of Ouro Preto Ouro Preto 35400-000 Brazil

In this paper, the authors present a modelling activity developed from a thematic project in the models and mathematical modelling class of the professional master"s degree program in mathematics education at the Federal University of Ouro Preto. The students enrolled in the class chose to study the theme Brazilian Public Politics. After several debates regarding the theme, the students were separated into three groups and each group chose a subtheme to study. The themes were IDH (index of human development), minimum wage and social security. As an example, a description of the thematic project about the minimum wage in Brazil is presented. The principal results obtained in the study of this theme include a discussion about the potentialities of the theme as a classroom activity in different levels of schooling. As an educational activity, the thematic project demonstrated itself to be greatly relevant, since not only did it provide the learning possibility of mathematics related to the issues studied, but also promoted various discussions regarding the theme, which, in our conception, contributes to the social-critical development of the students. Finally, from the point of view of applied mathematics and mathematics education, the development of a modelling activity from thematic projects showed itself to be a good source of researches.

关键词：数学建模活动社会保障专题数学教育专业批判在校学生人类发展指数硕士学位

Regeneration of critical-sized defects, in a goat model, using a dextrin-based hydrogel associated with granular synthetic bone substitute

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Regenerative Biomaterials 2021年第1期8卷 73-82页

作者： Isabel Pereira Jose Eduardo Pereira Luis Maltez Alexandra Rodrigues Catarina Rodrigues Manuela oliveira Dina MSilva Ana Rita Caseiro Justina Prada Ana Colette Mauricio Jose Domingos Santos Miguel Gama CEB Centre of Biological EngineeingUniversity of MinhoCampus de GualtarBraga 4710-057Portugal CECAV Animal and Veterinary Research CentreUniversity of Trias-os-Montes e Alto DouroVila Real 5001-801Portugal Department of Veterinary Sciences University of Tras-os-Montes e Alto DouroVila Real 5001-801Portugal Bios ckin Molecular and Cell Therapies S.A.Laboratorio CriovidaTecMaiaRua Engenheiro Frederico Ulrich 2650Moreira da Maia 4470-605Portugal Departamento de Clinicas Veterinarias Instituto de Ciencias Biomedicas de Abel Salazar(ICBAS)Universidade do Porto(UP)Rua de Jorge Viterbo Ferreiran°228Porto 4050-313Portugal Centro de Estudos de Ciencia Animal(CECA) Instituto de CienciasTecnologias e Agroambiente da Universidade do Porto(ICETA)Rua D.Manuel IApartado 55142Porto 4051-401 Portugal Centro de Investigaqao Vasco da Gama(CIVG)/Escola Universitaria Vasco da Gama(EUVG) Avenida Jose R.Sousa Femandesn°197 LordemaoCoimbra 3020-210Portugal REQUIMTE/LAQV Departamento de Engenharia Metalurgica e MateriaisFaculdade de EngenhariaUniversidade do PortoRua Dr Roberto FriasPorto 4200-495Portugal

The development of injectable bone substitutes(IBS)have obtained great importance in the bone re-generation field,as a strategy to reach hardly accessible defects using minimally invasive techniques and able to fit to irregular *** this scenario,the association of injectable hydrogels and bone graft granules is emerging as a well-established ***,in situ forming hydrogels have arisen as a new IBS *** in situ forming and injectable dextrin-based hydrogel(HG)was developed,aiming to act as a carrier of granular bone substitutes and bioactive *** this work,the HG was associated to a granular bone substitute(Bonelike)and implanted in goat critical-sized calvarial defects(14mm)for 3,6 and *** results showed that HG improved the han-dling properties of the Bonelike granules and did not affect its osteoconductive features,neither impairing the bone regener ation *** multipotent mesenchymal stromal cells from the umbilical cord,extracellular matrix hydrolysates and the pro-angiogenic peptide LLKKK18 were also combined with the *** bioactive agents did not enhance the new bone formation significantly under the conditions tested,according to micro-computed tomography and histological analysis.

关键词： polysaccharide injec table hydrogel granular ceramics Bonelike' bone regen eration calvarial defect