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Evinacumab for Homozygous Familial Hypercholesterolemia

四川生理科学杂志 2020年第3期 338-338页

作者： frederick j Raal

Background: Homozygous familial hypercholesterolemia is characterized by premature cardiovascular disease caused by markedly elevated levels of low-density lipoprotein(LDL) *** disorder is associated with genetic variants that result in virtually absent(null-null) or impaired(non-null) LDL-receptor ***-of-function variants in the gene encoding

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剑桥中国明代史

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1992年

作者：牟复礼(frederick W. Mote) 崔瑞德(Denis Twitchett)

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MUTATIONAL SPECTRA OF INDUCED MUTATIONS IN THE ad-3 REGION OF Neurospora crassa:EVIDENCE FOR MUTAGEN SPECIFICITY

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癌变．畸变．突变 1991年第S1期3卷 31-31页

作者： frederick j.de Serres Center for Life Sciences and Toxicology Research Triangle InstituteResearch Triangle ParkNC 27709U.S.A.

Specific-locus mutations induced in the ad-3region of two-component heterokaryons ofNeurospora have been compared by means ofMutational *** characterization ofad-3 mutations has revealed that there are majorclasses:gene/point mutations,multilocus deletionmutations and unknowns (mutants that grow toorapidly alone on minimal medium to be classified).

关键词： crassa Neurospora locus alone classified deletion ethal immediately

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Individual CTCF binding elements control V(D)j recombination at the Ig H locus

Individual CTCF binding elements control V(D)J recombination...

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第十届全国免疫学学术大会

作者： Sherry Lin Chunguang Guo Arthur Su Yu Zhang frederick W.Alt Program in Cellular and Molecular Medicine Boston Childrens Hospital

Immunoglobulin heavy chain(Ig H)variable region exons are assembled from V,D,and j gene segments during early B lymphocyte differentiation.A several megabase(Mb)region at the"distal"end of the mouse Ig H locus(Igh)contains hundreds of VHs,separated by an intergenic region from Igh Ds,jHs and constant region *** of Vs,Ds,and js

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The Effects of Chinese Herbal Medicine for Miscarriage on Decidual Micro-environment

The Effects of Chinese Herbal Medicine for Miscarriage on De...

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第十四届全国中药和天然药物学术研讨会

作者： Longzhu Piao Chie-Pein Chen Yung-Chi Cheng Rachel Masch frederick Schatz Charles j.Lockwood Shwu-Huey Liu jiang Zaoli jiang S.joseph Huang The Ohio State University

Objective Spontaneous abortion(SA)complicates about 15%of clinically recognized pregnancies and displays a pro-inflammatory decidual *** date,there is no effective prevention for ***01 is a multi-herbal formula been w...

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古典吉他精选曲集 The Renaissance guitar

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2013年

作者：弗雷德里克·诺德（frederick Noad）

本书包括独奏、二重奏和歌曲，涵盖了文艺复兴时期吉他与琉特琴作曲家的作品。

ISBN: (纸本)9787549529971

本书包括独奏、二重奏和歌曲，涵盖了文艺复兴时期吉他与琉特琴作曲家的作品。

关键词：六弦琴-世界-作品集

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The Use of SF<sub>6</sub>and GIS to Study Farfield Modeling of Ocean Outfall Plumes in Florida

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journal of Environmental Protection 2014年第11期5卷 1037-1052页

作者： frederick Bloetscher Fernando j. Pleitez Thomas Romah Ahmed Albasri Chase Dickinson Husayn El Sharif Kevin Matthews Trung-Duong Nguyen Lucrece Riche Frank Youngman Thomas P. Carsey jack Stamates john R. Proni Applied Research Center (ARC) Florida International University Miami FL USA Atlantic Oceanographic and Meteorological Laboratory Ocean Chemistry Division Miami FL USA Florida Atlantic University Civil Engineering Department Boca Raton FL USA

In june, 2004 and February, 2007, in field tracer studies were conducted on the Hollywood and South Central outfalls, using sulfur hexafluoride (SF6) as a tracer. The objective of these studies was to determine if the tracer could be detected in the farfield at significant distance, and if so, could this data be used to construct a model of the farfield plume. Prior models for farfield plume movement do not appear to comport well with the conditions in southeast Florida. Extensive research was conducted in southeast Florida on 4 outfalls, which led to the development of nearfield dilution equations for same. However farfield modeling of outfall plumes was difficult to accomplish because the tracers used are not detectable for significant distances. The SF6 resolved that problem and as a result the Hollywood outfall was used to construct a model. Two methods were investigated for modeling the plume, 1) the Eureqa formulation method and 2) the Gamma-Curve method. The concentrations in the x-y plane were first found by using the Eureqa formulation to calculate the concentration at each grid point given its depth and the concentration of the centerline at the same latitude. The plume models were generated using MATLAB that matched with the results actually seen in the field.

关键词： Ocean Outfall Treated Sewage Effluent Disposal Farfield Modeling Sulfur Hexafluoride

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Prevention of gob ignitions and explosions in longwall mining using dynamic seals

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International journal of Mining Science and Technology 2017年第6期27卷 999-1003页

作者： Brune jürgen F. Saki Saqib A. Department of Mining Engineering Colorado School of Mines CO 80401 USA Aldea Services LLC Frederick MD 21704 USA

Most, if not all longwall gob areas accumulate explosive methane-air mixtures that pose a deadly hazard to miners. Numerous mine explosions have originated from explosive gas zones(EGZs) in the longwall gob. Since 2010, researchers at the Colorado School of Mines(CSM) have studied EGZ formation in longwall gobs under two long-term research projects funded by the National Institute for Occupational Safety and Health. Researchers used computational fluid dynamics along with in-mine measurements. For the first time, they demonstrated that EGZs form along the fringe areas between the methane-rich atmospheres and the fresh air ventilated areas along the working face and present an explosion and fire hazard to mine workers. In this study, researchers found that, for progressively sealed gobs, a targeted injection of nitrogen from the headgate and tailgate, along with a back return ventilation arrangement, will create a dynamic seal of nitrogen that effectively separates the methane zone from the face air and eliminates the EGZs to prevent explosions. Using this form of nitrogen injection to create dynamic seals should be a consideration for all longwall operators.

关键词： Mine explosions Face ignitions Coal mining Longwall mining Methane

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高级宏观经济学基础

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作者： (Heijdra Ben j.)海德拉 (van der Ploeg frederick)范德普罗格

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古典吉他精选曲集

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2013年

作者： (比)弗雷德里克·诺德(frederick Noad)

本书包括独奏、二重奏和歌曲，涵盖了浪漫主义时期吉他与琉特琴作曲家的作品。

ISBN: (纸本)9787549529988

本书包括独奏、二重奏和歌曲，涵盖了浪漫主义时期吉他与琉特琴作曲家的作品。

关键词：六弦琴

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