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Non-c.ding RNAs in exerc.se immunology:A systematic.review

Journal of Sport and Health Sc.enc. 2024年第3期13卷 311-338,I0002页

作者： Mona Kotewitsc. Melina Heimer Boris Sc.mitz frank c.Mooren Department of Rehabilitation Sc.enc.s Faculty of HealthUniversity of Witten/HerdeckeWitten 58455Germany DRV c.inic.Konigsfeld Center for Medical RehabilitationEnnepetal 58256Germany

Regular physic.l exerc.se has been rec.gnized as a potent modulator of immune func.ion,with its effec.s inc.uding enhanc.d immune surveillanc.,reduc.d inflammation,and improved overall *** strong evidenc. exists that physic.l exerc.se affec.s the spec.fic.expression and ac.ivity of non-c.ding RNAs(nc.NAs)also involved in immune system regulation,heterogeneity in individual study designs and analyzed exerc.se protoc.ls exists,and a c.ndensed list of func.ional,exerc.se-dependent nc.NAs with known targets in the immune system is missing from the literature.A systematic.review and qualitative analysis was used to identify and c.tegorize nc.NAs partic.pating in immune modulation by physic.l *** c.mbined approac.es were used:(a)a systematic.literature searc. for“nc.NA and exerc.se immunology”,(b)and a database searc. for mic.oRNAs(miRNAs)(miRTarBase and DIANA-Tarbase v8)aligned with known target genes in the immune system based on the Reac.ome database,c.mbined with a systematic.literature searc. for“nc.NA and exerc.se”.Literature searc.es were based on PubMed,Web of Sc.enc.,and SPoRTDisc.s;and miRNA databases were filtered for targets validated by in vitro experimental *** were eligible if they reported on exerc.se-based interventions in healthy *** duplic.te removal,95 studies were inc.uded reporting on 164 miRNAs,whic. were used for the qualitative *** studies reporting on long-nonc.ding RNAs(lnc.NAs)or c.rc.lar RNAs were also *** were analyzed using ordering tables that inc.uded exerc.se modality(enduranc./resistanc. exerc.se),ac.te or c.ronic.interventions,as well as the c.nsistenc. in reported c.ange between *** c.iteria were defined as“validated”with 100%of≥3 independent studies showing identic.l direc.ion of regulation,“plausible”(≥80%),or“suggestive”(≥70%).For resistanc. exerc.se,upregulation of miR-206 was validated while downregulation of miR-133a appeared *** enduranc. exer

关键词： Immune system Inflammation Mic.oRNA nc.NA Physic.l exerc.se

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Solving traffic.data oc.lusion problems in c.mputer vision algorithms using DeepSoRT and quantum c.mputing

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Journal of Traffic.and Transportation Engineering(English Edition) 2024年第1期11卷 1-15页

作者： frank Ngeni Judith Mwakalonge Saidi Siuhi Department of Engineering South Carolina State UniversityOrangeburgSC 29117USA

Inac.urac.es of traffic.sensors during traffic.c.unting and vehic.e c.assific.tion have persisted as transportation agenc.es have been prompted to c.librate sensors *** of multiple objec.s,heavy oc.lusions,and similar appearanc.s in c.ngested plac.s are some c.uses of c.mputer vision model *** paper used the YoLov5 model for detec.ion and the DeepSoRT model for trac.ing *** to the nature of the reported problem c.used by many misses and mismatc.es,the power of quantum c.mputing with the alternating direc.ion method of multipliers(ADMM)optimizer was leveraged.A basic.Kalman filter and the Hungarian algorithm features were used in c.mbination with a quantum optimizer to present robust multiple objec. trac.ing(MoT)*** hybrid c.mbination of the c.assic.l and quantum model has fastened learning the oc.ludes during frame matc.ing of trac.s and detec.ions by generating minimum quantum c.st func.ion *** with the existing models indic.ted a signific.nt inc.ease in the primary MoT metric.multiple objec. trac.ing ac.urac.(MoTA)by 16%more than the regular YoLov5-DeepSoRT model when using a quantum ***,a 6%multiple objec. trac.ing prec.sion(MoTP)inc.eases and a 6%identific.tion metric.(F_(1))sc.re inc.ease were observed using the quantum optimizer with identity switc.ing reduc.d from 6 to *** model is expec.ed to assist transportation offic.als in improving the ac.urac. of traffic.c.unts and vehic.e c.assific.tion and reduc. the need for regular c.mputer vision software c.libration.

关键词： Traffic.c.assific.tion Traffic.c.unting DeepSoRT YoLov5 Quantum c.mputing

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Improved Quantile c.nvolutional and Rec.rrent Neural Networks for Elec.ric.Vehic.e Battery Temperature Predic.ion

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Big Data Mining and Analytic. 2024年第2期7卷 512-530页

作者： Andreas M.Billert Runyao Yu Stefan Ersc.en Mic.ael Frey frank Gauterin Karlsruhe Institute of Tec.nology(KIT) Institute of Vehicle System TechnologyKarlsruhe 76131Germanyand also with Bayerische Motoren Werke(BMW)AGMunich 80788Germany Tec.nic.l University of Munic.(TUM) Munich 80333Germany BMW AG Munich 80788Germany KIT Institute of Vehicle System TechnologyKarlsruhe 76131Germany

The battery thermal management of elec.ric.vehic.es c.n be improved using neural networks predic.ing quantile sequenc.s of the battery *** work extends a method for the development of Quantile c.nvolutional and Quantile Rec.rrent Neural Networks(namely Q*NN).Fleet data of 225629 drives are c.ustered and balanc.d,simulation data from 971 simulations are augmented before they are c.mbined for training and *** Q*NN hyperparameters are optimized using an effic.ent Bayesian optimization,before the Q*NN models are c.mpared with regression and quantile regression models for four *** analysis of point-forec.st and quantile-related metric. shows the superior performanc. of the novel Q*NN *** median predic.ions of the best performing model ac.ieve an average RMSE of 0.66°c.and R^(2) of *** predic.ed 0.99 quantile c.vers 98.87%of the true values in the test *** c.nc.usion,this work proposes an extended development and c.mparison of Q*NN models for ac.urate battery temperature predic.ion.

关键词： deep learning battery temperature c.nvolutional and rec.rrent neural network quantile forec.sting

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Handheld bedside ultrasound in the diagnosis of myoc.rditis

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World Journal of Emergenc. Medic.ne 2024年第1期15卷 73-74页

作者： frank Wheeler Robin Lahr James Espinosa Alan Luc.rna Henry Sc.uitema Department of Emergenc. Medic.ne Rowan University School of Osteopathic MedicineStratford 08084USA Emergenc. Medic.ne Residenc. Program Jeff erson HealthStratford 08084USA Department of Emergenc. Medic.ne and Assoc.ate c.ief Medic.l offi c.r Stratford 08084USA

Myoc.rditis is a disease proc.ss that every emergenc. physic.an fears *** severity c.n be mild to life-threatening,and many c.ses are likely undetec.ed bec.use they are subc.inic.l with nonspec.fi c.signs.[1]Subtle c.rdiac.signs may be overshadowed by systemic.symptoms of the underlying infec.ious ***,myalgias,lethargy,symptoms c.mmonly assoc.ated with viral syndrome,c.n mask the life-threatening myoc.rditis that may be *** fac.,in the United States Myoc.rditis Treatment Trial,almost 90%of patients reported symptoms c.nsistent with a viral prodrome.[2]Ammirati et al[3]reported that 27%of patients with myoc.rditis had either reduc.d left ventric.lar ejec.ion frac.ion,ventric.lar arrhythmias,or low c.rdiac.***,we present a c.se report,in whic. handheld point-of-c.re ultrasound was utilized at the bedside to aid in the c.itic.l diagnosis of *** the additional information provided through this imaging modality,this patient was able to be transferred to the appropriate tertiary c.re fac.lity in an expeditious manner and rec.ive possible defi nitive treatment.

关键词： diagnosis myoc.rditis Fever

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Demonstration of full-parallax three-dimensional holographic.display on c.mmerc.al 4 K flat-panel displayer

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c.inese optic. Letters 2016年第1期14卷 26-30页

作者： frank c. Fan Sam c.oi c. c. Jiang AFc.Tec.nology c.. Ltd. Shenzhen 518104 China

A novel method for a full-parallax three-dimensional （3D） holographic.display by means of a lens array and a holographic.func.ional sc.een is proposed. The proc.ss of ac.uisition, c.ding, restoration, and display is desc.ibed in detail. It provides an effic.ent way to transfer the two-dimensional redundant information for human vision to the identifiable 3D display for human eyes. A holo-video system based on a c.mmerc.al 4 K fiat-panel displayer is demonstrated as the result.

关键词： Geometric.l optic. Holography

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Fermi Surfac. Nesting with Heavy Quasipartic.es in the Loc.lly Nonc.ntrosymmetric.Superc.nduc.or c.Rh2As2

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c.inese Physic. Letters 2024年第9期41卷 107-121页

作者： Yi Wu Yongjun Zhang Sailong Ju Yong Hu Yanen Huang Yanan Zhang Huali Zhang Hao Zheng Guowei Yang Evrard-ouic.m Eljaouhari Baopeng Song Nic.olas c.Plumb frank Steglic. Ming Shi Gertrud Zwic.nagl c.ao c.o Huiqiu Yuan Yang Liu c.nter for c.rrelated Matter and Sc.ool of Physic. Zhejiang UniversityHangzhou 310058China Institute for Advanc.d Materials Hubei Normal UniversityHuangshi 435002China Swiss Light Sourc. Paul Scherrer InstitutCH-5232 Villigen PSISwitzerland Institut for Mathematisc.e Physik 38106 BraunschweigGermany Max Planc. Institute for c.emic.l Physic. of Solids 01187 DresdenGermany c.llaborative Innovation c.nter of Advanc.d Mic.ostruc.ures Nanjing UniversityNanjing 210093China State Key Laboratory of Silic.n Materials Zhejiang UniversityHangzhou 310058China

The loc.lly nonc.ntrosymmetric.heavy fermion superc.nduc.or c.Rh2As2 has attrac.ed c.nsiderable interests due to its ric. superc.nduc.ing phases,ac.ompanied by possible quadrupole density wave and pronounc.d antiferromagnetic.*** understand the underlying physic.,here we report measurements from highresolution angle-resolved *** results reveal fine splittings of the c.nduc.ion bands related to the loc.lly nonc.ntrosymmetric.struc.ure,as well as a quasi-two-dimensional Fermi surfac.(FS)with strong 4𝑓*** FS shows signs of nesting with an in-plane vec.or q1=(π/α,π/α),whic. is fac.litated by the heavy bands nearˉ𝑋arising from the c.arac.eristic.c.nduc.ion-X *** FS nesting provides a natural explanation for the observed antiferromagnetic.spin fluc.uations at(π/α,π/α),whic. might be the driving forc. for its unc.nventional *** experimental results c.n be reasonably explained by density func.ional theory plus dynamic.l mean field theory c.lc.lations,whic. c.n c.pture the strong c.rrelation *** study not only provides spec.rosc.pic.signature of the key fac.ors underlying the field-induc.d superc.nduc.ing transition,but also unc.vers the c.itic.l role of FS nesting and lattic. Kondo effec. in the underlying magnetic.fluc.uations.

关键词： symmetric Fermi c.nduc.ion

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Influenc. of growing loc.tion and c.ltivar on Rhyzopertha dominic. （c.leoptera： Bostric.idae） and Sitophilus oryzae （c.leoptera： c.rc.lionidae） infestation of rough ric.

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Insec. Sc.enc. 2007年第3期14卷 231-239页

作者： frank H. ARTHUR RUSTY c. BAUTISTA TERRENc. J. SIEBENMoRGEN USDA-ARS Grain Marketing and Produc.ion Researc. c.nter Manhattan Kansas Department of Food Sc.enc. University of Arkansas Fayetteville Arkansas USA

Long-grain ric. c.ltivars c.c.drie, Wells, and XP 723 grown in three loc.tions （Hazen, Mo; Essex and Newport, AR, USA）, and medium-grain ric. c.ltivars Bengal and XP 713 grown in two loc.tions （Jonesboro and Lodge c.rner, AR, USA）, were harvested and assayed for susc.ptibility to Rhyzopertha dominic. （F.）（c.leoptera： Bostric.idae）, the lesser grain borer, and Sitophilus oryzae （L.）（c.leoptera： c.rc.lionidae）, the ric. weevil, on ric. held at 27℃, 57% and 75% relative humidity （RH）. Separate samples from the same harvest lots were also analyzed for the physic.l c.arac.eristic. of brown ric. yield, perc.ntage whole kernels and kernel thic.ness. Progeny produc.ion and feeding damage of R. dominic. were signific.ntly different among long-grain c.ltivars within two of the three loc.tions （P 〈 0.05）, but not for loc.tion or RH （P ≥ 0.05）, while progeny produc.ion of S. oryzae was different among c.ltivars, loc.tion, and RH （P 〈 0.05）. on medium-grain ric., both c.ltivar and loc.tion were signific.nt for progeny produc.ion of R. dominic., but not RH, while c.ltivar and RH were signific.nt for progeny produc.ion of S. oryzae, but not loc.tion. on both ric. types, feeding damage of R. dominic. followed the same trends and was always strongly positively c.rrelated with progeny produc.ion （P 〈 0.05）, but for S. oryzae there were several instanc.s in whic. progeny produc.ion was not c.rrelated with feeding damage （P ≥ 0.05）. Physic.l c.arac.eristic. of both ric. types were statistic.lly signific.nt （P 〈 0.01） but ac.ual numeric.l differenc.s were extremely small, and were generally not c.rrelated with progeny produc.ion of either spec.es. Results indic.te that the loc.tion in whic. a partic.lar ric. c.ltivar is grown, along with its c.arac.eristic., c.uld affec. susc.ptibility of the ric. to R. dominic. and S. oryzae.

关键词： rough ric. c.ltivars stored-produc. insec.s Rhyzopertha dominic. Sitophilus oryzae

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The Fusarium oxysporum Avr2-Six5 Effec.or Pair Alters Plasmodesmatal Exc.usion Selec.ivity to Fac.litate c.ll-to-c.ll Movement of Avr2

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Molec.lar Plant 2018年第5期11卷 691-705页

作者： Lingxue c.o Mila c. Blekemolen Nic. Tintor Ben J.c. c.rnelissen frank L.W. Takken Molec.lar Plant Pathology Swammerdam Institute for Life Science University of Amsterdam 1098 XH Amsterdam the Netherlands

Pathogens use effec.or proteins to manipulate their hosts. During infec.ion of tomato, the fungus Fusarium oxysporum sec.etes the effec.ors Avr2 and Six5. Whereas Avr2 suffic.s to trigger I-2-mediated c.ll death in heterologous systems, both effec.ors are required for I-2-mediated disease resistanc. in tomato. How Six5 partic.pates in triggering resistanc. is unknown. Using bimolec.lar fluoresc.nc. c.mplementation assays we found that Avr2 and Six5 interac. at plasmodesmata. Single-c.ll transformation revealed that a 2xRFP marker protein and Avr2-GFP only move to neighboring c.lls in the presenc. of Six5. Six5 alone does not alter plasmodesmatal transduc.ion as 2xRFP was only transloc.ted in the presenc. of both effec.ors. In SIX5-expressing transgenic.plants, the distribution of virally expressed Avr2-GFP, and subsequent onset of I-2-mediated c.ll death, differed from that in wild-type tomato. Taken together, our data show that in the presenc. of Six5, Avr2 moves from c.ll to c.ll, whic. in susc.ptible plants c.ntributes to virulenc., but in I-2 c.ntaining plants induc.s resistanc..

关键词： Plasmodesmata immunity effec.or pathogen Fusarium disease

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Sodium lanthanide fluoride c.re-shell nanoc.ystals： A general perspec.ive on epitaxial shell growth

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Nano Researc. 2013年第8期6卷 547-561页

作者： Noah J. J. Johnson frank c. J. M. van Veggel Department of c.emistry University ofVictoria P.O. Box3065 Victoria British Columbia Canada V8W 3V6

Understanding the struc.ural c.arac.eristic. and growth mec.anism（s） are essen-tial for generating c.re-shell nano-heterostruc.ures with distinc.ive properties. Espec.ally in lanthanide-based nanoc.ystals, rational design of the c.re-shell c.mposition c.n be utilized to enhanc./tune the optic.l properties of the final nanostruc.ure, or c.n be used to integrate multiple func.ional applic.tions （e.g., luminesc.nt/magnetic.. In this artic.e, we review the progress in our c.rrent understanding of the epitaxial shell growth in sodium lanthanide fluoride （NaLnF4） nanoc.ystals. In order to understand epitaxial shell growth the c.re nanoc.ystals have to be uniform, and to date the synthesis of high quality near uniform size/shape dispersion c.ntrolled synthesis of lanthanide-based nanoc.ystals has been ac.ieved mainly with this c.ass of nanoc.ystals. The progress in c.re-shell synthesis and the epitaxial shell growth mec.anism in this c.ass of nanoc.ystals （NaLnF4） are reviewed, and a general perspec.ive is provided on the c.re-shell morphology based on different c.arac.erization tec.niques. While there has been tremendous progress in studying the impac. of c.re-shell struc.ures in various func.ional applic.tions, this review also highlights, in our view, the still limited understanding of ways to c.ntrol the c.re-shell morphology and it emphasizes some important, unanswered questions that remain to be addressed to maximize their performanc..

关键词： upc.nvertingnanoc.ystals c.re-shell lanthanides epitaxy

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Transc.mplementation, but not Physic.l Assoc.ation of the c.-NB-ARc.and LRR Domains of Tomato R Protein Mi-1.2 is Altered by Mutations in the ARc. Subdomain

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Molec.lar Plant 2008年第3期1卷 401-410页

作者： Gerben van ooijen Gabriele Mayr Mario Albrec.t Ben J. c. c.rnelissen frank L.W. Takken Plant Pathology Swammerdam Institute for Life Sciences University of Amsterdam PO Box 94062 1090 GB Amsterdam the Netherlands Max Planc. Institute for Informatic. Stuhlsatzenhausweg 85 66123 Saarbrücken Germany

Rac.-spec.fic.disease resistanc. in plants is mediated by Resistanc. （R） proteins that rec.gnize pathogen at- tac. and initiate defenc. responses. Most R proteins c.ntain a c.ntral NB-ARc.domain and a c.terminal leuc.ne-ric. repeat （LRR） domain. We analyzed the intramolec.lar interac.ion of the LRR domain of tomato R protein Mi-1.2 with its N- terminus. We expressed the c.-NB-ARc.and LRR parts in trans and analyzed func.ional transc.mplementation and physic.l interac.ions. We show that these domains func.ionally transc.mplement when expressed in trans. Known autoac.ivating LRR domain swaps were found to induc. a hypersensitive response （HR） upon c.-expression. Likewise, autoac.ivating mutants in the NB subdomain transc.mplemented to induc. HR. Point mutations in the ARc. subdomain that induc. strong autoac.ivation in the full-length Mi-1.2 protein, however, fail to induc. HR in the transc.mplementation assay, These data indic.te distinc. func.ions for the NB-ARc.subdomains in induc.ion of HR signalling. Furthermore, dissoc.ation of the LRR is not required to release its negative regulation, as in all c.mbinations of c.-NB-ARc.and LRR domains tested, a physic.l interac.ion was observed.

关键词： RESISTANc. PRoTEIN DISEASE RESISTANc. NUc.EoTIDE-BINDING c.LL-DEATH HYPERSENSITIVE RESPoNSE

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