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Impact of zinc and arginine on antioxidant status of weanling piglets raised under commercial conditions

Animal Nutrition 2019年第3期5卷 227-233页

作者： Nadia Bergeron frédéric guay departement des Sciences Animales Université Laval

The effects of dietary zinc and L-arginine supplements on the weight gain,feed efficiency,antioxidant capacity and oxidative status of weanling piglets raised under commercial conditions were examined.A total of 288 piglets aged 21 d were fed for 15 d a diet supplemented or not with 2,500 mg/kg of zinc(provided as zinc oxide)and 1% L-arginine *** 4 treatments were distributed in a randomized complete block design with 6 initial body weight categories(12 animals per pen).Access to feed and water was ad *** were analyzed as a 2 x 2 factorial experiment using the SAS MIXEd procedure,with zinc and arginine as the main independent *** collection day(d 8 and 15,samples were collected from the same 2 piglets in each pen before the morning feeding)was included as a third *** zinc supplement increased the average daily gain(AdG)from d 0 to 7.d 8 to 15 and d 0 to 15(0.289 vs.0.217 kg/d).average daily feed intake(Adfr)from d 8 to 15 and d 0 to 15(0.338 vs.0.279 kg/d)and the gain to feed(G:F)ratio from d 0 to 7 and d 0 to 15(0.86 vs.0.77)(Pdecreased the malondialdehyde concentration(zinc:4.37 vs.3.91 μmol/L,P= 0.005;arginine:4.38 vs.3.89 μmol/L,P = 0.002).Total antioxidant capacity and reduced glutathione(GSH)increased from d 8 to 15(0.953 vs.1.391 μmol/L,2.22 vs.3.37 μmol/L,Pdless of dietary *** and oxidized GSH concentrations on d 8 were higher in response to the combined supplements(zinc x arginine interaction.Pd either Zn-supplemented diet had a lower haptoglobin serum concentration(509 vs.1.417 mg/L;Pd piglet growth performance(AdG and AdFI)and oxidative status(based on malondialdehyde concentration).The arginine supplement had a limited effect on growth performance and oxidative status under these conditions.

关键词： Zinc Arginine Weanling piglets Antioxidant status Growth performance

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Feed supplementation with arginine and zinc on antioxidant status and inflammatory response in challenged weanling piglets

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Animal Nutrition 2017年第3期3卷 236-246页

作者： Nadia Bergeron Claude Robert frédéric guay département des sciences animales Université Laval

Although supplementing the diet with zinc oxide and arginine is known to improve growth in weanling piglets, the mechanism of action is not well understood. We measured the antioxidant status and inflammatory response in 48 weanling castrated male piglets fed diets supplemented with or without zinc oxide(2,500 mg Zn oxide per kg) and arginine(1%) starting at the age of 20 days. The animals were injected with lipopolysaccharide(100 μg/kg) on day 5. Half of them received another injection on day *** samples were taken just before and 6, 24 and 48 h after injection and the mucosa lining the ileum was recovered following euthanizing on days 7 and 14. Zinc supplementation increased reduced and total glutathione(GSH)(reduced and total) during days 5 to 7 and arginine decreased oxidized GSH measured on days 5 and 12 and the ratio of total antioxidant capacity to total oxidative status during days12 to 14. Zinc decreased plasma malondialdehyde measured on days 5 and 12 and serum haptoglobin measured on day 12 and increased both metallothionein-1 expression and total antioxidant capacity measured in the ileal mucosa on day 14. Tumour necrosis factor a concentration decreased from days 5 to12(all effects were significant at P dy shows that the zinc supplement reduced lipid oxidation and lipopolysaccharide-induced inflammation during the post-weaning period, while the arginine supplementation had only a limited effect.

关键词： Antioxidant Inflammation Zinc Arginine Piglet Weanling

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The Efficacy and Safety of a Patent Pending Combination of Ginger and Goldenrod Extracts on the Management of Cold Symptoms: A Randomized, double-Blind Controlled Trial

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Food and Nutrition Sciences 2012年第12期3卷 1651-1657页

作者： Johane guay Pierre Champagne Pascal Guibord Joerg Gruenwald analyze & realize ag Berlin Germany. Biopharmacopae Inc. Quebec City Canada Institut Privé de Chirurgie Quebec City Canada Statistician Lachine Canada 4analyze & realize ag Berlin Germany.

Objective: In a randomized, double-blind, exploratory, active-controlled trial, the efficacy and safety of a patent-pending combination of Ginger and Goldenrod extracts (BdI-630) in alleviating cold symptoms in community-dwelling adults was compared to a combination of standardized amounts of Echinacea (EC) components. Methods: 44 healthy adults, experiencing new onset of cold symptoms were randomly assigned to receive either BdI-630 (900 mg) or EC (500 mg) twice daily for 10 days. The severity of cold symptoms and the quality of life was assessed by self-reporting of subjects using the Wisconsin Upper Respiratory Symptom Survey (WURSS-21? 2004). Results: The intent-to-treat population (ITT) consisted of 44 subjects (n = 22 for BdI-630;n = 22 for EC). The modified ITT (mITT) population consisted of 40 subjects, excluding four subjects with major protocol deviations related to inclusion/exclusion criteria and/or use of prohibited drugs from the efficacy analysis (n = 3 for BdI-630 and n = 1 for EC). Results indicated a sig-nificant difference between the two groups: the superiority of BdI-630 over EC was particularly noticeable between day 1 and day 7, as demonstrated by a 14-fold difference of the mean percentage of change of total score from baseline in the mITT population. Adverse events (AEs) following the intake of BdI-630 were mostly limited to mild gastrointestinal intolerance in less than 10% of the subjects. Conclusions: BdI-630 was shown to be more effective than EC in alleviating cold symptoms in the adult population, particularly during the first 7 days of treatment. BdI-630 was very well tolerated by all subjects.

关键词： Randomized double-Blind Active-Controlled Trial Common Cold

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Single frequency WAAS Augmentation Observations (L1 vs. L5) on a Ground Based GPS L1 C/A Solution

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Positioning 2014年第3期5卷 70-83页

作者： Marc-Antoine Fortin Jean-Christophe guay René Jr. Landry école de Technologie Supérieure (éTS) Montréal Canada école de Technologie Supérieure (éTS) Montréal Canada

This paper presents observations on the WAAS L1 and L5 signals quality and their impact on the robustness of the navigation solution by quantifying the contributions of each broadcasted differential correction. This work is undertaken with the intent of defining performance benefits of L5 by dual frequency WAAS users and is to provide useful material for Minimum Operational Performance Standard (MOPS) development. In this perspective, a study of the WAAS signal characteristics is first carried out. The information gathered is then used to compare various GPS solutions in terms of frequency diversity, satellite diversity, pseudorange noise and different signal corrections and their impacts. These solutions are compared against a reference standalone GPS solution. All statistics are computed with respect to a post-processed Novatel Waypoint Real-Time Kinematics (RTK) GPS L1/L2 semi-codeless static solution, considered as the reference. A discussion on some simplifications with respect to specifications (i.e. MOPS) that could be considered by receiver manufacturers closes the paper. It is confirmed that the current WAAS navigation message definition is the same on both the L1 and L5 frequencies, the latter further being Manchester coded, thus avoiding data ambiguity. The +5 dB SNR on L5 has minor impacts in terms of reliability and continuous availability in the presented scenarios, but would become especially beneficial in hostile environments, despite a greater number of pulsed interferers. Another demonstration is that the WAAS message varies slightly from one WAAS satellite to another, even if corrections are generated centrally. Finally, it is observed that WAAS and GPS signals pseudorange noise are comparable on a “per frequency” basis.

关键词： GPS L1 WAAS L1 WAAS L5 MOPS Pseudorange Noise

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美国建筑材料市场全球变化和立足于中国的制造商展望生意的动态性

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国际木业 2008年第12期38卷 32-33页

作者： Phill guay 龙超

毫无疑问美国经济目前处于所有与木质建筑材料相关的人士曾经经历过的最深刻并可能时间最长的低迷时期。失业率很高并且在不断上升中，消费者信心空前低落，消费者支出也前所未有地处于低水平。几十年来，美国燃料消费的增长，各种类型... 详细信息

毫无疑问美国经济目前处于所有与木质建筑材料相关的人士曾经经历过的最深刻并可能时间最长的低迷时期。失业率很高并且在不断上升中，消费者信心空前低落，消费者支出也前所未有地处于低水平。几十年来，美国燃料消费的增长，各种类型的不动产价值下跌，商业投资支出几乎停止，全球对于美国产品需求下降。除了不断增长的丧失抵押品赎回权以外，不良贷款率，银行贷款意愿下降，

关键词：建筑材料市场美国经济动态性生意消费者产品需求不良贷款银行贷款

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新生儿复苏

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国外医学（护理学分册） 1992年第6期11卷 255-257页

作者： guay J 王荣娟

新生儿复苏的成功与否,对于降低其死亡率至关重要。本文系统地介绍了新生儿复苏的方法。

关键词：复苏术新生儿

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如何用双重氧化法处理卡林金矿石

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湖南冶金 1980年第3期 70-73页

作者： W.J.guay 张燎原

自1965年以来,新蒙特(Newmont)采矿公司附属的卡林(Carlin)金矿公司在内华达州(Nevada)卡林经营了一座2400吨/日提取金的氰化厂。该金矿呈细粒浸染赋存于氧化矿中,并被认为是由热液沉积作用所构成的。矿体的主要部分

关键词：氧化法矿浆金矿电炉炼钢金属矿物氯气含碳物质矿石换热器热交换器铁矿物黄铁矿次氯酸盐次氯酸钙室内试验实验室试验批量试验搅拌速度

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乙基紫苏霉素

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国外医药(抗生素分册) 1984年第5期 440-446页

作者： david R.P.guay 林晓峰孙东建

乙基紫苏霉素的合成已由Wright在1976年所阐述,它是紫苏霉素的新的半合成衍生物。由于它对氨基糖苷抗生素耐药菌有活性,动物实验毒性低,因而,被人们选用来进行更深入的研究。近年来,在加拿大市场上已有出售,其商品名为Netromycin,并即... 详细信息

乙基紫苏霉素的合成已由Wright在1976年所阐述,它是紫苏霉素的新的半合成衍生物。由于它对氨基糖苷抗生素耐药菌有活性,动物实验毒性低,因而,被人们选用来进行更深入的研究。近年来,在加拿大市场上已有出售,其商品名为Netromycin,并即将得到食品药物管理局(FdA)的批准和广泛地应用。在加拿大,乙基紫苏霉素已经批准用于治疗由大肠杆菌、变形杆菌、克雷白氏杆菌、肠细菌、柠檬酸菌和葡萄球菌等敏感菌所引起的感染(在美国还未得到批准)。此

关键词：紫苏霉素丁胺卡那霉素氨基糖碳水化合物链烷基乙基托普霉素

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2009年澳大利亚经济回顾:复苏之路

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经济资料译丛 2010年第2期 35-45页

作者： guay C. Lim（） Chew Lian Chua（） Edda Claus（） Sarantis Tsiaplias（）孙党华（译）谢琪（译）不详厦门大学财政系厦门大学国际经济与贸易系 361005

1引言正如图1所示，2009年全球GdP增速急剧下降，世界贸易也随之大幅下滑。受七国集团经济下滑影响，全球总产出下降了大概1．1％。就如多米若骨牌，美国增长率下降了2．7％，英国下降了4．4％，欧洲地区下降了4．2％。

关键词： 2009年经济回顾澳大利亚世界贸易经济下滑七国集团欧洲地区 GdP

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全脂和低脂乳制品摄入对日间动态血压和其他心血管代谢危险因素的影响

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中华高血压杂志 2020年第12期28卷 1235-1235页

作者： Rancourt-Bouchard M Gigleux I guay V Charest A Saint-Gelais d Vuillemard JC Lamarche B Couture P 袁源(摘译) 练桂丽(审校) 不详

乳制品及其脂肪成分对心血管健康的影响程度仍不确定。目的:该研究旨在评估摄入低脂牛奶和富含γ-氨基丁酸(gamma-aminobutyric acid,GABA)的全脂干酪对日间动态血压和其他心血管代谢危险因素的影响。方法:在该项交叉对照试验中,正常高... 详细信息

乳制品及其脂肪成分对心血管健康的影响程度仍不确定。目的:该研究旨在评估摄入低脂牛奶和富含γ-氨基丁酸(gamma-aminobutyric acid,GABA)的全脂干酪对日间动态血压和其他心血管代谢危险因素的影响。方法:在该项交叉对照试验中,正常高值日间血压的健康男性和女性55例随机分配至3个为期6周的等能量膳食阶段中,每个包括:①无乳制品(对照膳食),②每日3份1%脂肪牛奶,③每日1份天然富含GABA的31%脂肪切达干酪。

关键词：切达干酪脂肪成分乳制品心血管健康随机分配 GABA

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