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Antidepressant,anxiolytic and anti-nociceptive activities of ethanol extract of Steudnera colocasiifolia *** leaves in mice model

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Journal of Coastal Life Medicine 2015年第11期 890-894页

作者： Mohammad Shah Hafez Kabir Mohammed Munawar hossain Md.Mominur Rahman Shabbir Ahmad Abul Hasanat Tanvir Ahmad chowdhury Md.Akramul Hoque Nishan Chakrabarty Md.Shakhawat hossain Department of Pharmacy International Islamic University ChittagongBangladesh

Objective:To estimate the antidepressant,anxiolytic and antinociceptive activities of ethanol extract of Steudnera colocasiifolia ***(***)***:Swiss albino mice treated with 1%Tween solution,standard drugs and ethanol extract of ***,respectively,were subjected to the neurological and antinociceptive *** tail suspension test and forced swimming test were used for testing antidepressant activity,where the parameter is the measurement of immobility *** activity was evaluated by hole board ***-nociceptive potential of the extract was also screened for centrally acting analgesic activity by using formalin induced licking response model and acetic acid induced writhing test was used for testing peripheral analgesic ***:Ethanol extract of *** significantly decreased the period of immobility in both tested models(tail suspension and forced swimming models)of antidepressant *** the hole board model,there was a dose dependant(at 100 and 200 mg/kg)and a significant increase in the number of head dipping by comparing with control(1%Tween solution)(P<0.05 and P<0.001).In formalin induced licking model,a significant inhibition of pain compared to standard diclofenac sodium was observed(P<0.05 and P<0.001).In acetic acid induced test,there was a significant reduction of writhing response and pain in mice treated with leaves extract of *** at 200 mg/kg body weight(P<0.05 and P<0.001).Conclusions:The results proofed the prospective antidepressant,anxiolytic and antinociceptive activities of ethanol extract of *** leaves.

关键词： Steudnera colocasiifolia K.Koch Antinociceptive Antidepressant Anxiolytic Hole board

Advantages of Computed Tomography (CT) in Endoscopic Septopasty

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International Journal of Otolaryngology and Head & Neck Surgery 2020年第6期9卷 185-193页

作者： Md. Ashraful Islam Towsif Bin Mamoon Farid Uddin Milki Nazmul hossain chowdhury Saif Rahman Khan A. S. M. Rahman Tareq Mohammad MBBS FCPS FICS FRCS (Glasgow) Otolaryngology-Head & Neck Surgery Bangladesh Medical College Hospital Dhaka Bangladesh MBBS ENT Bangladesh Medical College Hospital Dhaka Bangladesh MBBS FCPS ENT Bangladesh Medical College Hospital Dhaka Bangladesh MBBS ENT National Institute of ENT Dhaka Bangladesh MBBS MCPS DLO MRCPS (Glasgow) Bangladesh Medical College Hospital Dhaka Bangladesh

Background and objective: Nasal obstruction is the most frequent presentation to the otolaryngologist all over the world. Symptoms are multisystem involvement such as headache, epistaxis, ophthalmological, otological, upper and lower respiratory tract infections;and many more. Septoplasty is commonly performed for nasal septal deviation as a primary indication of nasal airway obstruction. Physical examination, anterior rhinoscopy and nasal endoscopy are considered the gold standard for detecting septal deviation. Computed tomography (CT) can also be used to evaluate the nasal septum, anatomical variants and unveils the associated sinonasal diseases. This study aimed to find out the advantages of CT in endoscopic septoplasty for all out benefits to the patients. Patients and methods: 168 patients of nasal septal deviation were selected from 2015 to 2018 in the Bangladesh Medical and Popular Medical College Specialized Hospital. Age ranged between 10 years to 70 years of age. CT scanning in both coronal, axial and sagittal sections had been done in all patients after proper history taking, physical examination, anterior rhinoscopy and nasal endoscopy. Endoscopic septoplasty alone and/or other ancillary procedures were performed in all 168 patients under general anesthesia. Results: Amongst 168 patients, male was 116 (69%) and female was 52 (31%) with a ratio 2.2:1. Maximum 58 (35%) reported in 31 to 40 years and 48 (29%) was found in 21 to 31 years of age. Hypertrophied inferior turbinate (HIT) 54 (32%) and 48 (29%) concha bullosa (CB) were associated with 168 septal deviation. Associated pathologies like maxillary antral cyst 68 (40%) and maxillary sinusitis 62 (37%) were documented. Conclusion: CT scanning unveils the abnormal anatomic variants and associated sinonasal pathologies along with nasal septal deviation. Endoscopic septoplasty, correction of the anatomical variants and complete surgical c

关键词： Computed Tomography Endoscopic Septoplasty Advantage

Surgical management of clinoidal meningiomas: 10 cases analysis

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Neuroimmunology and Neuroinflammation 2018年第5期5卷 21-30页

作者： Shamsul Alam Bipin Kumar Chaurasia Narendra Shalike Abu Naim Wakil Uddin Dhiman chowdhury Akhlaque hossain Khan Ayub Ansari Kanak Kanti Barua Mashiur Rahman Majumder Department of Neurosurgery Bangabandhu Sheikh Mujib Medical UniversityDhaka1000Bangladesh Department of Neurosurgery Comilla Medical CollegeComilla3500Bangladesh

Aim: The purpose of this article is to advocate standard skull base technique for removing the clinoidal meningioma and to delineate the technique's advantages that aid in achieving an improved extent of tumor resection and enhancing the patients' overall outcome, specially their visual outcome. Methods: A retrospective analysis was performed on 10 consecutive patients with clinoidal meningiomas who underwent surgical resection at the Bangabandhu Sheikh Mujib Medical University and other private clinics between May 2013 and July 2016. A standard pterional craniotomy technique consisting of extradural anterior clinoidectomy, coupled with optic canal unroofing and optic nerve sheath opening was used in all patients. All patients had thorough preoperative and postoperative ophthalmological evaluations. The follow-up period ranged from 6 to 42 months. Results: Total resection was achieved in 5 (50.0%) of the 10 patients in this series. The majority of the patients with preoperative visual impairment experienced significant visual improvement 7 of 10 patients;70.0%). Conclusion: In the majority of patients with clinoidal meningiomas, total resection may be achieved with minimal complications. For large tumors encasing the optic nerve and internal carotid artery, or for those tumors causing preoperative visual impairment, use of the cranial base technique delineated in this study may lead to significant improvement in the patients' visual and overall outcomes.

关键词： Clinoidal meningiomas pterional craniotomy extradural anterior clinoidectomy

孟加拉国Bhanugach西部保育林用地类型变化(英文)

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Journal of Forestry Research 2008年第3期19卷 193-198页

作者： Md. Abdul Halim Abdus Shahid Mohammad Shaheed hossain chowdhury Mst. Nazmun Nahar Md. Shawkat Islam Sohel Nuruddin Md. Jahangir Masao Koike Department of Forestry and Environmental Science Shahjalal University of Science and Technology Bangladesh Space Research and Remote Sensing Organization (SPARRSO) Forest Policy Laboratory Department of Forest ScienceFaculty of AgricultureShinshu University Department of Geology and Mining Rajshahi University Department of Civil and Environmental Engineering Shahjalal University of Science and Technology

应用遥感和地理信息系统调查了孟加拉国Sylhet林业分局所辖的Bhanugach西部保育林从1988年到2006年间用地类型的变化。应用了监督和非监督两种方法,用全球定位系统搜集了地面控制点。地理信息系统软件制成地图。结果表明,植被覆盖从198... 详细信息

应用遥感和地理信息系统调查了孟加拉国Sylhet林业分局所辖的Bhanugach西部保育林从1988年到2006年间用地类型的变化。应用了监督和非监督两种方法,用全球定位系统搜集了地面控制点。地理信息系统软件制成地图。结果表明,植被覆盖从1988年的1826hm2大幅地降低到1996年的1714.85hm2,随着协同管理措施的实施,植被覆盖自1996年后逐年增长到2006年的1847.83hm2。在没有其他类型的用地转变成裸地的情况下,裸地变化与植被覆盖间成反比。18年间水体面积从1988年的307.67hm2增加到1996年379.53hm2,96-97年间略有下降,1997年以后直到2006年基本保持不变。本文还提出了将遥感技术和地理信息系统应用于用地类型变化及地理信息系统数据库创建的一些建议。

关键词：土地利用地理信息系统森林孟加拉国亚洲

Outcomes of Percutaneous Nephrolithotomy with or without Nephrostomy Tube: A Comparative Study

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Journal of Biosciences and Medicines 2019年第3期7卷 52-60页

作者： Mohammad Ibrahim Ali Prodyut Kumar Saha Shafiqul Alam chowdhury Nahid Kamal Mostafiger Rahman Sazzad hossain Ripan Debnath Mohammad Saruar Alam A. K. M. Shahidur Rahman Kamrul Islam Department of Urology Dhaka Medical College Hospital Dhaka Bangladesh District Hospital Sherpur Bangladesh Department of Urology Prime Medical College Rangpur Bangladesh Apollo Hospital Ltd. Gulshan Dhaka Bangladesh Department of Nephrology Bangabandhu Sheikh Mujib Medical University (BSMMU) Dhaka Bangladesh Zilla Sadar Hospital Habigong Bangladesh

Objectives: To compare the outcomes of Percutaneous Nephrolithotomy (PCNL) with or without nephrostomy tube. Materials & Methods: This prospective comparative study intended to compare the outcomes between PCNL without nephrostomy tube and PCNL with nephrostomy tube. A total of 50 cases of renal stone disease planned for PCNL in Dhaka Medical College Hospital from July 2015 to June 2017, were included in this study according to the statistical calculation. Cases were randomly allocated to group A (PCNL without nephrostomy tube) and group B (PCNL with nephrostomy tube). Each group consisted of 25 patients. The outcome variables were post operative pain, requirement of analgesic, leakage of urine and post operative hospital stay. Data were analyzed and compared by statistical tests. Results: No significant differences were found regarding age (p = 0.95), sex (p = 0.55) and operation time (p = 0.36) between two groups. Post operative pain (p p p p Conclusions: Percutaneous nephrolithotomy without nephrostomy tube is better than percutaneous nephrolithotomy with nephrostomy tube in selective cases. It significantly reduces post operativepain, analgesic requirement and postoperative hospital stay. So percutaneous nephrolithotomy without nephrostomy tube is safe and effective.

关键词： Nephrostomy Percutaneous Nephrolithotomy (PCNL) Renal Stone Disease

Chemically Modified Uridine Molecules Incorporating Acyl Residues to Enhance Antibacterial and Cytotoxic Activities

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International Journal of Organic Chemistry 2015年第4期5卷 232-245页

作者： Sarkar M. A. Kawsar Hamida A. Ara Sheikh Aftab Uddin Mohammed K. hossain Shagir A. chowdhury Abul F. M. Sanaullah Mohammad A. Manchur Imtiaj Hasan Yukiko Ogawa Yuki Fujii Yasuhiro Koide Yasuhiro Ozeki Laboratory of Carbohydrate and Protein Chemistry Department of Chemistry Faculty of Science University of Chittagong Chittagong Bangladesh The Institute of Marine Science Faculty of Science University of Chittagong Chittagong Bangladesh Department of Pharmacy Faculty of Biological Science University of Chittagong Chittagong Bangladesh Department of Microbiology Faculty of Biological Science University of Chittagong Chittagong Bangladesh Laboratory of Glycobiology and Marine Biochemistry Department of Life and Environmental System Science Graduate School of NanoBio Sciences Yokohama City University Yokohama Japan Divisions of Microbiology Graduate School of Pharmaceutical Science Nagasaki International University Nagasaki Japan

A new N-acetylsulfanilylation series of uridine have been synthesized in good yield using direct acylation method and afforded the 5’-O-N-acetylsulfanilyluridine. In order to obtain newer products, the 5’-O-N-acetylsulfanilyluridine derivative was further transformed to a series of 2’,3’-di-O-acyl derivatives containing a wide variety of functionalities in a single molecular framework. The chemical structures of the newly synthesized compounds were confirmed on the basis of their FTIR, 1H-NMR spectroscopy, physicochemical properties and elemental analysis. All the synthesized uridine derivatives were tested for their in vitro antibacterial activity against six human pathogenic bacterial strains and for comparison standard antibiotic Ampicillin was also determined. The study revealed that the selectively acylated deriva-tives 5’-O-N-acetylsulfanilyl-2’,3’-di-O-lauroyluridine and 5’-O-N-acetylsulfanilyl-2’,3’-di-O-pivaloyluridine showed highest inhibition against Staphylococcus aureus and Bacillus cereus, respectively. We also observed that the introduction of hexanoyl, decanoyl, lauroyl, myristoyl and pivaloyl groups, the antibacterial functionality of the compound uridine increases. Another noteworthy observation was that the uridine derivatives were found comparatively more effective against Gram-positive microorganisms than those of Gram-negative microorganisms. In addition, the test chemicals were also tested for cyto-toxicity by brine shrimp lethality bioassay and compounds showed different rate mortality with different concentrations.

关键词： Uridine Synthesis Structure Spectroscopy Antibacterial Cytotoxicity

A Comparative Analysis of Culture Media for Optimizing the Mycelial Growth and Sporulation of Stemphylium vesicarium Cause of White Blotch of Onion

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Journal of Agricultural Science and Technology(A) 2015年第6期5卷 440-448页

作者： Hosna Ara chowdhury Nurul Islam Belal hossain Moudood Ahmed Sayed Mohsin Rafiqul Islam Department of Plant Pathology Sher-e-Bangla Agricultural University Dhaka 1207 Bangladesh Department of Botany University of Dhaka Dhaka 1000 Bangladesh

Low Ca^2＋ Content and Ca^2＋/Na^＋ Ratio in Leaf Tissues Determine Salinity Tolerance in Spanish Type Groundnut （Arachis hypogeal L.）

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Journal of Agricultural Science and Technology(B) 2018年第2期8卷 71-84页

作者： Mohammad Akram hossain chowdhury Mohammad Shahidur Rashid Bhuyia Mohammad Shah-e-Alam Mohammad Abul Kalam Azad Department of Agricultural Extension Ministry of Agriculture Dhaka 1215 Bangladesh Department of Genetics and Plant Breeding Sher-e-Bangla Agricultural University Sher-e-Bangla Nagar Dhaka 1207 Bangladesh Department of Genetics and Plant Breeding Bangladesh Agricultural University Mymensingh 2202 Bangladesh Plant Breeding Division Bangladesh Institute of Nuclear Agriculture (BINA) BAU Campus Mymensingh 2202 Bangladesh