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Epidemio.o.y o. iso.a.ed fo.t burns in children presenting to.a.Queensla.d pa.dia.ric burns centre—a.two.yea. study in wa.mer clima.e

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Burns & Tra.ma 2017年第1期5卷 58-63页

作者： florence Ngu Bha.eshkuma. Pa.el Cra.g McBride Pegg Leditschke Children’s Burns Centre Department of Paediatric SurgeryLady Cilento Children’s Hospital501 Stanley StreetSouth Brisbane QLD 4101Australia Centre fo. Children’s Burns a.d Tra.ma.Resea.ch Queensland Children’s Medical Research InstituteUniversity of QueenslandQueenslandAustralia

Ba.kgro.nd: Euro.ea. studies o. pa.dia.ric fo.t burns repo.t sca.ds a. the lea.ing ca.se. Mecha.isms o. injury a.e different in wa.mer clima.es. We so.ght to.cha.a.terize the mecha.isms a.d o.tco.es o. iso.a.ed fo.t burns in o.r po.ula.io.. Metho.s: Retro.pective review o. a.pro.pectively co.lected da.a.a.e o. a.l children a.ed 0–15 yea.s presenting to.a.Queensla.d pa.dia.ric burns centre o.er a.26-mo.th perio.. No.-pa.a.etric a.a.yses such a. the Ma.n-Whitney U a.d Pea.so. Chi-squa.e were used. Results: There were 218 children with fo.t burns trea.ed o.er a.perio. o. 2 yea.s a.d 2 mo.ths o. which 214 ha. co.plete reco.ds. There were significa.tly mo.e bo.s tha. girls (n=134, 62.6% cf. n=80, 37.4%, pa.ing mecha.ism o. injury wa. a.co.ta.t burn a.co.nting fo. 63.1% (n=135) fo.lo.ed by sca.ds (23.8%, n=51). Frictio., fla.e a.d chemica. burns were a.mino.ity but were significa.tly deeper (p=0.03) a.d significa.tly mo.e likely to.require gra.ting (p=0.04) a.d sca. ma.a.ement (po.pa.ed to.co.ta.t a.d sca.d burns. Co.clusio.s: In o.r po.ula.io., co.ta.t burns a.e the mo.t co.mo. mecha.ism o. injury ca.sing burns to.the feet. The lea.ing a.tio.o.y is ca.pfire burns, which a.co.nt fo. o.e-third o. a.l burns to.the feet. Preventio. ca.pa.gns ta.geted a. this po.ula.io. co.ld significa.tly reduce the burden o. mo.bidity fro. these burns. Frictio., fla.e a.d chemica. burns co.stitute a.mino.ity o. pa.ients but a.e deeper a.d mo.e likely to.require skin gra.ting a.d sca. ma.a.ement.

关键词： Epidemio.o.y Fo.t burns Pa.dia.ric Sca.d a.stra.ia Ca.pfire

Micro.ebus murinus： a.no.el pro.ising no.-huma. prima.e mo.el o. spina. co.d injury

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Neura. Regenera.io. Resea.ch 2018年第3期13卷 421-422页

作者： Ga.ta. Po.len florence Evelyne Perrin University o. Mo.tpellier Institut National de la Santé et de la Recherche Médicale Unit 1198 Montpellier France depa.tment o. neuro.urgery gui de chauliac hospital montpellier university medical centerMontpellier France

The number o. peo.le a.fected by spina. co.d injuries （SCI） ra.ges fro. 2.5 to.4 millio. wo.ldwide. Tra.ma.ic SCI induces a.prima.y injury due to.initia. mecha.ica. impa.t tha. ca.ses fo.a. cellula. a.d blo.d-spina. co.d ba.rier da.a.es. Subsequently, seco.da.y injuries resulting fro. infiltra.io. o. periphera. mo.o.ytes, ischemia. edema.infla.ma.io., glia. sca. a.d cystic ca.ities fo.ma.io. a. well a. excito.o.icity trigger cellula. demise a.d prevent spo.ta.eo.s a.o.a. regro.th. Seco.da.y da.a.es, including a.grega.io. o. extra.ellula. ma.rix pro.ein a. the lesio. epicenter, thus grea.ly a.plify impa.rments induced by the initia. mecha.ica. da.a.e.

关键词： Micro.ebus murinus a.no.el pro.ising no.-huma. prima.e mo.el o. spina. co.d injury SCI

Pla.ticity o. ca.lo.a. neuro.s in the co.tra.esio.a. co.tex fo.lo.ing tra.ma.ic bra.n injury

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Neura. Regenera.io. Resea.ch 2023年第6期18卷 1257-1258页

作者： a.exa.dra.Cho.sepia. La.ra.Empl florence M.Ba.eyre Institute o. Clinica. Neuro.mmuno.o.y Biomedical Building and Clinic of the Ludwig-Maximilians Universität MünchenMunichGermany

Tra.ma.ic bra.n injury(TBI) represents a.significa.t ca.se o. disa.ility *** crea.es a.va.t a.ra. o. da.a.ing ma.ro.a.d micro.co.ic cha.ges in the a.fected bra.n a.ea.s),ra.ging fro. neuro.a. cell dea.h,cha.ges in structura. spine integrity a.d dyna.ics to.a.o.a. injury a.d o.e ra.l neuro.a. circuit disruptio.,ultima.ely lea.ing to.functio.a. a.d co.nitive deficits in bo.h huma.s a.d a.ima. mo.els(N udo.2013).

关键词： injury tra.ma.ic co.tex

Child Upbringing a.d Delinquency： Implica.io. fo. So.ieta. Develo.ment in Nigeria

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So.io.o.y Study 2013年第7期3卷 515-522页

作者： florence a. Undiya.ndeye Federa. Co.lege o. Educa.io. Obudu Nigeria

This pa.er investiga.ed the influence o. pa.enta. child upbringing styles a.d juvenile delinquency a.d the implica.io. fo. so.ieta. develo.ment. a.to.a. number o. 35 fema.e a.d ma.e delinquent inma.es o. Children Co.rectio.a. Centre in Cro.s River Sta.e a.d 35 fema.e a.d ma.e no.-delinquents fro. a.no.ma. scho.l a.ed fro. 12 yea.s to.17 yea.s to.k pa.t in the study. The Child Rea.ing Questio.na.re （CRQ） designed by the resea.cher wa. used fo. da.a.co.lectio.. Two.hypo.heses were fo.mula.ed to.guide the study. Chi-squa.e wa. used in testing the study hypo.heses a. .05 level o. significa.ce. The result o. the da.a.a.a.ysis sho.ed tha. pa.enta. child-rea.ing style ha. a.significa.t influence o. the three a.pects o. disho.est beha.io.r, na.ely lying, stea.ing, a.d trua.cy, a.d pa.ents＇ bo.ding with their children is a.so.significa.t. Ba.ed o. the findings, it wa. reco.mended a.o.g o.hers tha. pa.ents sho.ld a.o.t mo.e o. a.tho.ita.ive child upbringing styles. Pa.ents a.e expected to.guide a.d mo.ify the beha.io.r o. their children to.co.fo.m with the a.cepta.le beha.io.rs in so.iety a. well a. pa.ticipa.e in a.tivities a.med a. preventing crime o. diso.der being co.mitted by their children.

关键词： Pa.enta. child upbringing styles children delinquent beha.io.rs pa.ents

In vivo.a.tro.yte repro.ra.ming fo.lo.ing spina. co.d injury

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Neura. Regenera.io. Resea.ch 2024年第3期19卷 487-488页

作者： Ya.nick N.Gerber florence E.Perrin MMDN University of MontpellierEPHEINSERMMontpellierFrance Institut Universita.re de Fra.ce(IUF) ParisFrance

Ha.mful a.d helpful ro.es o. a.tro.ytes in spina. co.d injury(SCI):SCI induce gra.a.le senso.y,mo.o. a.d a.to.o.ic impa.rments tha. co.rela.e with the lesio. severity a.d the ro.tro.ca.da. lo.a.io. o. the injury *** a.sence o. spo.ta.eo.s a.o.a. regenera.io. a.ter injury results fro. neuro.-intrinsic a.d neuro.-extrinsic ***,no. o.ly a.ult neuro.s displa. limited ca.a.ility to.regro. a.o.s but a.so.the injury enviro.ment co.ta.ns inhibito.s to.a.o.a. regenera.io. a.d a.la.k o. gro.th-pro.o.ing *** o.her cell po.ula.io.s tha. respo.d to.the lesio.,rea.tive a.tro.ytes were first co.sidered a. o.ly detrimenta. to.spo.ta.eo.s a.o.a. ***,a.tro.ytes.

关键词： injury impa.rment pro.ra.ming

Recent pro.ress in lympho.eno.s a.a.to.o.is

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Pla.tic a.d a.sthetic Resea.ch 2023年第1期10卷 710-718页

作者： Guido.Gia.a.o.e florence Belva Depa.tment o. Lympha.ic Surgery AZ Sint-MaartenMechelen 2800Belgium

Brea.t ca.cer-rela.ed lymphedema.BCRL)is a.debilita.ing diso.der a.fecting a. estima.ed 1 in 5 wo.en a.d men trea.ed fo. brea.t ***,super micro.urgica. techniques ha.e a.va.ced in recent yea.s a.d no. pro.ide better o.tio.s fo. the trea.ment o. lymphedema.a.lo.ing timely surgica. interventio. tha. ca. dela. o. even prevent lympha.ic *** a.a.to.o.is(LVa.,a.physio.o.ic pro.edure tha. resto.es lympha.ic dra.na.e by co.necting functio.ing lympha.ic vessels with nea.by veins,ha. been sho.n to.be bo.h minima.ly inva.ive a.d highly *** a.tho.s describe inno.a.ive a.pro.0}hes to.LVa.tha. will help o.timize o.tco.es fo. pa.ients with BCRL.

关键词： Lympho.eno.s a.a.to.o.is lymphedema super micro.urgery

Influences o. initia. po.o.ity,stress tria.ia.ity a.d Lo.e pa.a.eter o. pla.tic defo.ma.io. a.d ductile fra.ture

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a.ta.Mecha.ica.So.ida.Sinica 2017年第5期30卷 493-506页

作者： Ying-So.g Ma.Do.g-Zhi Sun florence a.drieux Ke-Shi Zha.g Co.lege o. Civil Engineering a.d a.chitecture Guangxi UniversityKey Lab of Disaster Prevention and Structural SafetyGuangxi Key Lab Disaster Prevention and Engineering SafetyNanning 530004China Depa.tment o. Mining Engineering Shanxi Datong UniversityDatong 037003China Fra.nho.er Institute fo. Mecha.ics o. Ma.eria.s IWM Woehlerstrasse 1179108 FreiburgGermany

Lo.a. mecha.ica. pro.erties in a.uminum ca.t co.po.ents a.e inho.o.eneo.s a. a.co.- sequence o. spa.ia. distributio. o. micro.tructure, e.g., po.o.ity, inclusio.s, gra.n size a.d a.m spa.ing o. seco.da.y dendrites. In this wo.k, the effect o. po.o.ity is investiga.ed. Ca.t co.po.ents co.ta.n vo.ds with different sizes, fo.ms, o.ienta.io.s a.d distributio.s. This is a.pro.ima.ed by a.po.o.ity distributio. in the fo.lo.ing. The a.m o. this pa.er is to.in- vestiga.e the influence o. initia. po.o.ity, stress tria.ia.ity a.d Lo.e pa.a.eter o. pla.tic defo.ma.io. a.d ductile fra.ture. a.micro.echa.ica. mo.el with a.spherica. vo.d lo.a.ed a. the center o. the ma.rix ma.eria., ca.led the representa.ive vo.ume element （RVE）, is de- velo.ed. Fully perio.ic bo.nda.y co.ditio.s a.e a.plied to.the RVE a.d the va.ues o. stress tria.ia.ity a.d Lo.e pa.a.eter a.e kept co.sta.t during the entire co.rse o. lo.0}ing. Fo. this purpo.e, a.multi-po.nt co.stra.nt （MPC） user subro.tine is develo.ed to.prescribe the lo.0}ing. The results o. the RVE mo.el a.e used to.esta.lish the co.stitutive equa.io.s a.d to.further investiga.e the influences o. initia. po.o.ity, stress tria.ia.ity a.d Lo.e pa.a.eter o. ela.tic co.sta.t, pla.tic defo.ma.io. a.d ductile fra.ture o. a. a.uminum die ca.tin~ a.lo..

关键词： Stress tria.ia.ityLo.e pa.a.eterVo.dDuctile fra.tureRVE

Fa.ting a. a.precurso. to.high-fa. diet enha.ces mito.ho.dria. resilience in Dro.o.hila.mela.o.a.ter

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Insect Science 2024年第6期31卷 1770-1788页

作者： florence Hunter-Ma.sea. Simo. BCo.mier Rebeka. Stra.g a.d Nico.a. Picha.d Depa.tment o. Chemistry a.d Bio.hemistry Universitéde MonctonMonctonNew BrunswickCanada New Brunswick Centre fo. Precisio. Medicine MonctonNew BrunswickCanada

Cha.ges in diet type a.d nutrient a.a.la.ility ca. impo.e significa.t enviro.menta. stress o. o.ga.isms,po.entia.ly co.pro.ising physio.o.ica. functio.s a.d repro.uctive *** na.ure,dra.a.ic fluctua.io.s in dieta.y reso.rces a.e o.ten o.served a.d a.justments to.resto.e cellula. ho.eo.ta.is a.e crucia. to.survive this type o. *** this study,we expo.ed ma.e Dro.o.hila.mela.o.a.ter to.two.mo.ula.ed dieta.y trea.ments:o.e witho.t a.fa.ting perio. befo.e expo.ure to.a.high-fa. diet a.d the o.her with a.24-h fa.ting *** then investiga.ed mito.ho.dria. meta.o.ism a.d mo.ecula. respo.ses to.these *** to.a.high-fa. diet witho.t a.preceding fa.ting perio. resulted in disrupted mito.ho.dria. respira.io.,no.a.ly a. the level o. co.plex *** the o.her ha.d,a.sho.t fa.ting perio. befo.e the high-fa. diet ma.nta.ned mito.ho.dria. ***,tra.script a.unda.ce o. genes a.so.ia.ed with mito.ha.y,hea.sho.k pro.eins,mito.ho.dria. bio.enesis,a.d nutrient sensing pa.hwa.s increa.ed either slightly o. significa.tly fo.lo.ing a.fa.ting perio. a.d rema.ned sta.le when flies were subsequently put o. a.high-fa. diet,wherea. a.dra.tic decrea.e o. a.mo.t a.l tra.script a.unda.ces wa. o.served fo. a.l these pa.hwa.s when flies were expo.ed directly to.a.high-fa. ***,mito.ho.dria. enzyma.ic a.tivities sho.ed less va.ia.io. a.ter the fa.ting perio. tha. the trea.ment witho.t a.fa.ting ***,o.r study sheds light o. the mecha.istic pro.ective effects o. fa.ting prio. to.a.high-fa. diet a.d highlights the meta.o.ic flexibility o. Dro.o.hila.mito.ho.dria.in respo.se to.a.rupt dieta.y cha.ges a.d ha.e implica.io. fo. a.a.ta.io. o. species to.their cha.ging enviro.ment.

关键词： dieta.y mo.ula.io. fa.ting high-fa. diet meta.o.ic flexibility mito.ho.dria. meta.o.ism stress respo.se

Silico.e ma.rices fo. co.tro.led dexa.etha.o.e relea.e:to.a.d a.better understa.ding o. the underlying ma.s tra.spo.t mecha.isms

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Regenera.ive Bio.a.eria.s 2023年第1期10卷 498-509页

作者： Thitipho.n Ro.gtho.g a.a. Qno.ch Ma.ia.Ma.e Gehrke La.rent Pa.co. Pa.lo.o.iveira.florence Da.ede Jeremy Verin Christo.he Vincent Jea.-Fra.co.s Willa.t florence Siepma.n Juergen Siepma.n Univ.Lille INSERMCHU LilleU1008F-59000 LilleFrance Univ.Lille UMR CNRS 8207UMETF-59655 Villeneuve d’AscqFrance

Dexa.etha.o.e-lo.0}ed silico.e ma.rices o.fer a. interesting po.entia. a. inno.a.ive drug delivery systems,*** the trea.ment o. inner ea. disea.es o. fo. ***,very lo.g drug relea.e perio.s a.e ta.geted:severa. yea.s/*** renders the develo.ment a.d o.timiza.io. o. no.el drug pro.ucts cumberso.e:experimenta. feedba.k o. the impa.t o. the device design is o.ta.ned very slo.ly.a.better understa.ding o. the underlying ma.s tra.spo.t mecha.isms ca. help fa.ilita.ing resea.ch in this field.a.va.iety o. silico.e films were prepa.ed in this study,lo.0}ed with a.o.pho.s o. crysta.line *** po.ymo.phic drug fo.ms were investiga.ed,the film thickness wa. a.tered a.d the drug o.tio.a.ly pa.tia.ly/co.pletely excha.ged by much mo.e wa.er-so.uble dexa.etha.o.e‘pho.pha.e’.Drug relea.e studies in a.tificia. perilymph,sca.ning electro. micro.co.y,o.tica. micro.co.y,differentia. sca.ning ca.o.imetry,X-ra. diffra.tio. a.d Ra.a. ima.ing were used to.elucida.e the physica. sta.es o. the drugs a.d po.ymer,a.d o. the systems’structure a. well a. dyna.ic cha.ges thereo. upo. expo.ure to.the relea.e *** pa.ticles were initia.ly ho.o.eneo.sly distributed thro.gho.t the *** hydro.ho.icity o. the ma.rix fo.mer very much limits the a.o.nts o. wa.er penetra.ing into.the system,resulting in o.ly pa.tia. drug *** mo.ile drug mo.ecules diffuse o.t into.the surro.nding enviro.ment,due to.co.centra.io. ***,Ra.a. ima.ing revea.ed tha. even very thin silico.e la.ers(a. effectively tra. the drug fo. pro.o.ged perio.s o. *** physica. sta.e o. the drug(a.o.pho.s,crysta.line)did no. a.fect the resulting drug relea.e kinetics to.a.no.ewo.thy extent.

关键词： silico.e ma.rix drug relea.e mecha.ism dexa.etha.o.e dexa.etha.o.e pho.pha.e Ra.a. ima.ing