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On a Measure of Non-compactness for Some Classical Operators

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Acta Mathematica Sinica,English Series 2006年第6期22卷 1847-1862页

作者： David E.EDMUNDS Alberto fiorenza Alexander MESKHI School of Mathematics Cardiff University Dipartimentodi Costruzioni e Metodi Matematici in Architettura Scuola Normale Superiore

The measure of non-compactness is estimated from below for various operators, including the Hardy-Littlewood maximal operator, the fractional maximal operator and the Hilbert transform, all acting between weighted Lebesgue spaces. The identity operator acting between weighted Lebesgue spaces and also between the counterparts of these spaces with variable exponents is similarly analysed. These results enable the lack of compactness of such operators to be quantified.

关键词： measure of non-compactness maximal functions singular integrals embeddings weight

Brain Interactions between Extinction and Reconsolidation in the Treatment of Fear Memories

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Neuroscience & Medicine 2011年第3期2卷 232-238页

作者： Dagieli Sartor Natália Gindri fiorenza Jociane de Carvalho Myskiw Iván Izquierdo 不详

Memory traces become labile at the time of retrieval, and this initiates two protein synthesis-dependent processes in the brain: extinction, which inhibits their further retrieval, and reconsolidation, which may enhance retrieval or change the memory’s content. Extinction may itself suffer reconsolidation. Interactions between these processes may be applied to the treatment of fear memories, such as those underlying the post-traumatic stress disorder.

关键词： Memory Extinction Learning Reconsolidation Fear Memories

Hydrogen breath test for the diagnosis of lactose intolerance,is the routine sugar load the best one?

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World Journal of Gastroenterology 2008年第40期14卷 6204-6207页

作者： fiorenza Argnani Mauro Di Camillo Vanessa Marinaro Tiziana Foglietta Veronica Avallone Carlo Cannella Piero Vernia Gastroenterologia A e Scienza dell'Alimentazione Sapienza Università di Roma

AIM: To evaluate the prevalence of lactose intolerance (LI) following a load of 12.5 g in patients diagnosed as high-grade malabsorbers using the hydrogen breath test (HBT)-***: Ninety patients showing high-grade malabsorption at HBT-25 were submitted to a second HBT with a lactose load of 12.5 *** hydrogen production,area under the curve of hydrogen excretion and occurrence of symptoms were ***: Only 16 patients (17.77%) with positive HBT-25 proved positive at *** production was lower as compared to HBT-25 (peak value 21.55 parts per million (ppm) ± 29.54 SD vs 99.43 ppm ± 40.01 SD; P < 0.001).Symptoms were present in only 13 *** absence of symptoms during the high-dose test has a high negative predictive value (0.84) for a negative low-dose *** presence of symptoms during the first test was not useful for predicting a positive low-dose test (positive predictive value 0.06-0.31).CONCLUSION: Most patients with a positive HBT-25 normally absorb a lower dose of lactose and a strict lactose restriction on the basis of a "standard" HBT is,in most instances,***,the 25 g lactose tolerance test should probably be substituted by the 12.5 g test in the diagnosis of LI,and in providing dietary guidelines to patients with suspected lactose malabsorption/intolerance.

关键词：乳糖酶缺乏乳糖吸收不良氢呼吸测试乳糖不耐性

Sex effect on presenilins expression in post-natal rat brain

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Advances in Bioscience and Biotechnology 2013年第12期4卷 1086-1094页

作者： Paola Piscopo Sonia Canterini Valentina Carletti Paolo Rosa Alessio Crestini Maria Teresa fiorenza Annamaria Confaloni Department of Cellular Biology and Neuroscience Section of Clinics Diagnosis and Therapy of Central Nervous System Diseases Istituto Superiore di Sanità Rome Italy Department of Cellular Biology and Neuroscience Section of Clinics Diagnosis and Therapy of Central Nervous System Diseases Istituto Superiore di Sanità Rome Italy Department of Psychology Section of Neuroscience “Sapienza” University of Rome Rome Italy Department of Psychology Section of Neuroscience “Sapienza” University of Rome Rome Italy

Presenilin 1 and presenilin 2 are widely expressed during brain development. Several mutations in these proteins have been associated with autosomal-dominant inherited forms of Alzheimer disease. Their expression is regulated by various cellular and extracellular factors, which change with age and sex. Both age and sex are key risk factors for Alzheimer’s disease, but the issue of whether the expression of presenilins is influenced by the sex during early postnatal development of the brain has been poorly investigated so far. In this study, we report that transcript levels of presenilins, and the subset of neurons expressing these proteins in various brain areas of the developing post-natal brain are different in male and female rats, suggesting that their function(s) may contribute to sexual dimorphism in the brain, both at morphological and functional levels.

关键词： Development Sex Presenilins γ-Secretase Rats Sexual Dimorphism

Neutrophil gelatinase-associated lipocalin does not predict acute kidney injury in heart failure

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World Journal of Clinical Cases 2020年第9期8卷 1600-1607页

作者： fiorenza Ferrari Elisa Scalzotto Pasquale Esposito Sara Samoni Flavio Mistrorigo Lilia Maria Rizo Topete Massimo De Cal Grazia Maria Virzì Valentina Corradi Rossella Torregrossa Roberto Valle Stefania Bianzina Nadia Aspromonte Matteo Floris Alessandro Fontanelli Alessandra Brendolan Claudio Ronco Department of Nephrology Dialysis&Transplantation International Renal Research Institute VicenzaSt.Bortolo HospitalVicenza 36100Italy Department of Internal Medicine NephrologyDialysis and Transplantation ClinicsGenoa University and IRCCS Policlinico San MartinoGenova 16132Italy Department of Cardiology Coronary Intensive Care UnitSt.Bortolo HospitalVicenza 36100Italy Department of Cardiology Coronary Intensive Care UnitChioggia HospitalVenezia 36100Italy Neonatal and Pediatric Intensive Care Unit G.Gaslini InstituteGenoa 16147Italy Department of Cardiovascular and Thoracic Sciences Catholic University of the Sacred Heart Agostino Gemelli FoundationRome 00168Italy Division of Nephrology and Dialysis Azienda Ospedaliera G.BrotzuPiazzale Ricchi n°1Cagliari 09134Italy

BACKGROUND Acute cardiorenal syndrome type 1(CRS-1)is defined by a rapid cardiac dysfunction leading to acute kidney injury(AKI).Neutrophil gelatinaseassociated lipocalin(NGAL)is expressed on the surface of human neutrophils and epithelial cells,such as renal tubule cells,and its serum(sNGAL)and urinary have been used to predict AKI in different clinical *** To characterize CRS-1 in a cohort of patients with acute heart diseases,evaluating the potentiality of sNGAL as an early marker of *** We performed a retrospective cohort,multi-centre *** January 2010 to December 2011,we recruited 202 adult patients admitted to the coronary intensive care unit(CICU)with a diagnosis of acute heart failure or acute coronary *** monitored the renal function to evaluate CRS-1 development and measured sNGAL levels within 24 h and after 72 h of CICU *** Overall,enrolled patients were hemodynamically stable with a mean arterial pressure of 92(82-107)mmHg,55/202(27.2%)of the patients developed CRS-1,but none of them required *** the NGAL delta value(AUC 0.40,95%CI:0.25-0.55)nor the NGAL peak(AUC 0.45,95%CI:0.36-0.54)or NGAL cutoff(≥140 ng/mL)values were statistically significant between the two groups(CRS-1 vs no-CRS1 patients).The area under the ROC curve for the prediction of CRS-1 was 0.40(95%CI:0.25-0.55)for the delta NGAL value and 0.45(95%CI:0.36-0.54)for the NGAL peak ***,in multivariate analysis,the risk of developing CRS-1 was correlated with age>60 years,urea nitrogen at admission and 24 h-urine output(AUC 0.83,SE=60.5%SP=93%),while sNGAL was not significantly *** In our population,sNGAL does not predict CRS-1,probably as a consequence of the mild renal injury and the low severity of heart ***,these data might suggest that patient selection should be taken into account when considering the utility of NGAL measurement as a biomarker of kidney damage.

关键词： Cardiorenal syndrome type 1 Acute kidney injury Biomarker Neutrophil gelatinase-associated lipocalin

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日常加工问题的实用解决方案

现代制造 2012年第22期 30-31页

作者： Jeff Jaje William fiorenza Ingersoll Cutting Tools公司

为模具应用领域加工刚才与一般的生产加工方式或为其他市场加工是不一样的。下面是一些实用的解决方案，可解决日常模具粗加工操作中碰到的加工问题。

关键词：加工方式加工操作模具

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牛鲨：海洋新杀手

新发现 2015年第8期 70-74页

作者： fiorenza Gracci 邹沁

电影《大白鲨》为大白鲨树立了海洋第一杀手的形象。但在电影问世40年后的今天，另一种鲨鱼盖过了它的风头，成为新一代海洋杀手。这个物种直到最近还远离公众的视野，它的大名“牛鲨”之所以能为人所知，是缘于2011年以来留尼旺岛连续... 详细信息

电影《大白鲨》为大白鲨树立了海洋第一杀手的形象。但在电影问世40年后的今天，另一种鲨鱼盖过了它的风头，成为新一代海洋杀手。这个物种直到最近还远离公众的视野，它的大名“牛鲨”之所以能为人所知，是缘于2011年以来留尼旺岛连续发生的几起惨案。在发生的15起鲨鱼袭击事件中（6起致命），有12起被归于牛鲨所为，证据是它那不对称的双颌留下的标志性印记。

关键词：杀手海洋牛袭击事件大白鲨标志性不对称电影

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任重而道远的“禁塑令”

法语学习 2016年第6期 46-48页

作者： fiorenza Gracci 赵蕴哲

2016年1月1日起，法国将禁止在商店收银台使用一次性塑料袋（不论是收费的还是免费的）。2017年，此禁塑令的范围将扩展到果蔬称重用的塑料袋：这些塑料袋必须含有30%的生物基材料，并且这一比例以每年一个百分点的速度增长，直到使它... 详细信息

2016年1月1日起，法国将禁止在商店收银台使用一次性塑料袋（不论是收费的还是免费的）。2017年，此禁塑令的范围将扩展到果蔬称重用的塑料袋：这些塑料袋必须含有30%的生物基材料，并且这一比例以每年一个百分点的速度增长，直到使它们能够100％在居民家里堆肥为止。

关键词：塑料袋一次性收银台果蔬

Unusual Detection of Lathosterol in amniotic Fluids Investigated for the Determination of Cholesterol and 7-Dehydrocholesterol for Suspected Smith-Lemli-Opitz Syndrome

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american Journal of Analytical Chemistry 2014年第4期5卷 249-257页

作者： Veniero Gambaro fiorenza Farè Andrea Barlocco Federico Maggi Giuseppe Simoni Lucia Dell’Acqua Chiara Rusconi Gabriella Roda Dipartimento di Scienze Farmaceutiche “Pietro Pratesi” University of Milan Milan Italy Laboratorio TOMA srl Busto Arsizio Italy

The Smith-Lemli-Opitz syndrome (SLOS), is an autosomal recessive disorder caused by a 7-dehydrocholesterol reductase deficiency, which is characterized by abnormally elevated amniotic fluid 7-DHC (7-dehydrocholesterol) concentrations. A GC/FID (gas-chromatography with a flame ionization detector) and GC/MS (gas-chromatography with a mass detector) method was optimized for the detection of cholesterol and 7-DHC in amniotic fluids. The quantitative determination of cholesterol in 39 control amniotic fluids evidenced that between the fourth and fifth month of pregnancy the levels of this analyte are quite constant, the concentration of total and free cholesterol being respectively 10.3 μg·mL﹣1 (SD = ±3.6) and 1.7 μg·mL﹣1 (SD = ±0.91), while the analysis of 60 amniotic fluids potentially related to SLOS, showed a higher variability of cholesterol levels. Moreover, in 13 samples an analyte which did not correspond either to cholesterol or to 7-DHC was detected. A GC/MS investigation allowed us to identify this compound as lathosterol, a precursor of cholesterol in the biosynthetic pathway.

关键词： Lathosterol Cholesterol SLO Syndrome amniotic Fluid GC/FID GC/MS