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Brain Interactions between Extinction and Reconsolidation in the Treatment of Fear Memories

Brain Interactions between Extinction and Reconsolidation in the Treatment of Fear Memories

作     者:Dagieli Sartor Natália Gindri Fiorenza Jociane de Carvalho Myskiw Iván Izquierdo 

作者机构:不详 

出 版 物:《Neuroscience & Medicine》 (神经系统科学与医药(英文))

年 卷 期:2011年第2卷第3期

页      面:232-238页

学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主  题:Memory Extinction Learning Reconsolidation Fear Memories 

摘      要:Memory traces become labile at the time of retrieval, and this initiates two protein synthesis-dependent processes in the brain: extinction, which inhibits their further retrieval, and reconsolidation, which may enhance retrieval or change the memory’s content. Extinction may itself suffer reconsolidation. Interactions between these processes may be applied to the treatment of fear memories, such as those underlying the post-traumatic stress disorder.

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