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Impact of Coronary Chronic Total Occlusion on Long-term Clinical Outcome in Patients with Unprotected Left Main Disease Undergoing Percutaneous Coronary Intervention

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Cardiology Discovery 2022年第3期2卷 145-151页

作者： Imad Sheiban filippo figini Valeria Gaspartto Claudio Moretti filippo Leonardo Shaoliang Chen Fabrizio D’Ascenzo Interventional Cardiology P.Pederzoli HospitalPeschiera del GardaVerona 37019Italy Division of Cardiology Chivasso HospitalChivassoTorino 10034Italy Cardiology and Catheter Laboratory Nanjing First HospitalNanjing Medical UniversityNanjingJiangsu 210006China Division of Cardiology University of TurinTurin 8-10124Italy.

Objectives:Reported data regarding the prevalence,prognostic impact,and safety and efficacy of revascularization of coronary chronic total occlusion(CTO)in patients with left main coronary artery(LMCA)disease who undergo percutaneous coronary intervention(PCI)are *** aim of the present study was to compare clinical outcomes among patients with LMCA disease undergoing *** were compared between those with and without coronary CTO and between those with CTO who had successful and unsuccessful CTO recanalization ***:All consecutive patients with significant LMCA disease(>50%stenosis at coronary angiography)who underwent PCI between July 2014 and December 2018 were retrospectively included in our *** primary endpoint of the study was long-term *** endpoints included the incidence of myocardial infarction,repeat percutaneous or surgical revascularization,stroke,and stent ***:Between July 2014 and December 2018,578 patients underwent PCI for LMCA disease at Pederzoli Hospital and University of Turin were *** were divided into 3 groups:group A:374(65%)patients without CTO,group B:108(19%)patients with untreated or unsuccessfully treated CTO,and group C:96(17%)patients with successfully treated *** a median follow-up of(1090±279)days,there were no statistically significant differences between the groups in terms of the primary and secondary ***,there was a trend towards higher mortality in patients with untreated or unsuccessfully treated CTO(13%vs.19%vs.14%in groups A,B,and C,respectively;P=0.12).The primary and secondary endpoints were further analyzed based on the presence or absence of myocardial viability:subgroup C1:54(56%)patients with successful percutaneous transluminal coronary angioplasty(PTCA)having viability,and subgroup C2:42(44%)patients with successful PTCA not having *** was a trend toward a statistically significant higher rate of death among patients

关键词： Percutaneous coronary interventions Left main coronary artery disease Coronary chronic total occlusion Myocardial viability

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