检索结果-南通市图书馆

Antiglycation and antioxidant activities of the crude extract and saponin fraction of Tribulus terrestris before and after microcapsule release

引用

Journal of Integrative Medicine 2022年第2期20卷 153-162页

作者： Célia Cristina Malaguti Figueiredo Amanda da Costa Gomes filipe oliveira granero Joao Luiz Bronzel Junior Luciana Pereira Silva Valdecir Farias Ximenes Regildo Márcio Goncalves da Silva Institute of Chemistry São Paulo State UniversityAraraquaraSão Paulo 14800-060Brazil Educational Foundation of the City of Assis AssisSão Paulo 19807-130Brazil Department of Chemistry School of SciencesSão Paulo State UniversityBauruSão Paulo 17033-360Brazil Department of Biotechnology School of SciencesHumanities and LanguagesSão Paulo State UniversityAssisSão Paulo 19806-900Brazil

Objective:The present study investigated antiglycation and antioxidant activities of crude dry extract and saponin fraction of Tribulus *** also developed a method of microencapsulation and evaluated antiglycation and antioxidant activities of crude dry extract and saponin fraction before and after microcapsule ***:Antiglycation activity was determined by relative electrophoretic mobility(REM),free amino groups and inhibition of advanced glycation end-product(AGE)*** activity was determined by 2,2-diphenyl-1-picrylhydrazyl(DPPH),ferric ion-reducing antioxidant power(FRAP),nitric oxide(NO)and thiobarbituric acid reactive species(TBARS)*** were prepared using maltodextrin as wall material and freeze-drying as encapsulation *** characterization of microcapsules was evaluated by scanning electron microscopy,and encapsulation efficiency and microcapsule release were determined by total saponins *** and antioxidant assays were performed using crude dry extract and saponin fraction of *** before and after ***:Saponin fraction showed an increase of 32.8%total ***-performance liquid chromatography-mass spectrometry analysis showed the presence of saponins in the obtained *** evaluation by REM demonstrated that samples before and after release presented antiglycation activity similar to bovine serum albumin treated with ***,samples inhibited AGE formation,highlighting treatment with saponin fraction after release(89.89%).Antioxidant tests demonstrated antioxidant activity of the *** dry extract before encapsulation presented the highest activities in DPPH(92.00%)and TBARS(32.49%)*** fraction before encapsulation in FRAP test(499μmol Trolox equivalent per gram of dry sample)and NO test(15.13μmol nitrite formed per gram of extract)presented the highest ***:This study presen

关键词： Glycation Microencapsulation Oxidative stress Saponins Tribulus terrestris

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Dysregulated microRNAs in type 2 diabetes and breast cancer:Potential associated molecular mechanisms

引用

World Journal of Diabetes 2024年第6期15卷 1187-1198页

作者： Alex Cleber Improta-Caria filipe Ferrari João Lucas Penteado Gomes Paloma Brasilio Villalta Úrsula Paula RenóSoci Ricardo Stein Edilamar M oliveira Laboratory of Biochemistry and Molecular Biology of the Exercise Physical Education and Sport SchoolUniversity of São PauloSão Paulo 05508-030Brazil Graduate Program in Cardiology and Cardiovascular Sciences Federal University of Rio Grande do SulHospital de Clínicas de Porto AlegrePorto Alegre 90035003Brazil Laboratory of Metabolic Disorders(Labdime) School of Applied SciencesUniversity of Campinas-UNICAMPCampinas 13484-350Brazil Departments of Internal Medicine Molecular Pharmacology and PhysiologyCenter for Regenerative MedicineUSF Health Heart InstituteMorsani College of MedicineUniversity of South FloridaTampaFL 33602United States

Type 2 diabetes(T2D)is a multifaceted and heterogeneous syndrome associated with complications such as hypertension,coronary artery disease,and notably,breast cancer(BC).The connection between T2D and BC is established through processes that involve insulin resistance,inflammation and other *** this comprehension the specific cellular and molecular mechanisms linking T2D to BC,especially through microRNAs(miRNAs),remain *** are regulators of gene expression at the post-transcriptional level and have the function of regulating target genes by modulating various signaling pathways and biological ***,the signaling pathways and biological processes regulated by miRNAs that are associated with T2D and BC have not yet been *** review aims to identify dysregulated miRNAs in both T2D and BC,exploring potential signaling pathways and biological processes that collectively contribute to the development of BC.

关键词： Type 2 diabetes Breast cancer MicroRNAs Molecular mechanisms

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Recompositions of Buus＇（1547）RicercariFrom His Libro primo.., in Manuscript P-Cug MM 242 and the Didactic Processes of the Friars of the Santa Cruz Monastery in Coimbra.

引用

History Research 2013年第6期3卷 423-440页

作者： filipe Mesquita de oliveira Universidade de l~vora l~vora Portugal

The purpose of this articleis to address the presence of seven recomposed ricercari by Jacques Buus in the Music Manuscript 242 from the Library of the University of Coimbra in Portugal （P-Cug MM 242）. These recompositions, probably copied in the third quarter of the 16th century, were made after the previously copied Buus＇s ricercari in Music Manuscript 48 （P-Cug MM 48） of the same library, which were based on the Libro primo de ricercari a quattrovoci, published in Venice in 1547 by Antonio Gardane. In this paper, the author intend to focus in two main aspects of the research done on this subject. The first topic concerns the score-format of both manuscripts 48 ＆ 242, which testify the instrumental activity in mid-sixteenth century Portugal. The author will demonstrate that this format served once, in the Santa Cruz Monastery in Coimbra, as a didactic tool in the teaching of counterpoint through the music of a northern European master such as Jacques Buus. The copies in the manuscripts were never intended to be used as a performing support--they contain many errors of vertical coordination between the voices that make the performance impossible. The second topic focuses on Buus＇ recomposed ricercari, which were the object of many cuts, brief recomposed bridges, newly inserted sections, and written glosa figurations. Through these recompositions, the author will describe the theoretic assimilation of formal processes, of style, mode, counterpoint and performing practice. The achievement of this paper is to offer historic musicology researchers a new perspective about the enormous influence that Buus＇ ricercari from his Libro primo.., had in the learning processes of music composition and in the development of didactic and performing practices in the Santa Cruz Monastery in Coimbra, during the mid-sixteenth century.

关键词： Jacques Buus P-Cug MM 242 Ricercare Portuguese instrumental music from the 16h century Scoreformat manuscripts

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Antiglycation,antioxidant,antiacne,and photoprotective activities of crude extracts and triterpene saponin fraction of Sapindus saponaria ***:An in vitro study

引用

Asian Pacific Journal of Tropical Biomedicine 2022年第9期12卷 391-399页

作者： Regildo M.G.Silva Gustavo R.Martins Laura M.B.Nucci filipe O.granero Célia C.M.Figueiredo Patrícia S.Santiago Luciana P.Silva Laboratory of Herbal Medicine and Natural Products Department of BiotechnologyFaculty of SciencesHumanities and LanguagesSão Paulo State UniversityAssisSão PauloBrazil Institute of Chemistry São Paulo State UniversityAraraquaraSão PauloBrazil São Paulo State University Campus de RegistroRegistroSão PauloBrazil Fundação Educacional do Município de Assis AssisSão PauloBrazil

Objective:To evaluate the photoprotective,antioxidant,antiglycation,and antiacne activities of crude extract(CESs)and triterpene saponin fraction(TSSs)of Sapindus ***:HPLC-MS purification was performed on a Symmetry TM C18 *** saponins were identified by a UV *** activity was evaluated by DPPH and O_(2)^(−)radicals scavenging,and FRAP and TBARS *** activity was assessed by relative electrophoretic mobility and inhibition of advanced glycation end products(AGEs)***,antiacne activity was determined by inhibition of Cutibacterium acnes,and photoprotective effect was evaluated by Mansur’s ***:Most of the triterpene saponins detected in the fraction by HPLC-MS analysis were hederagenin as the *** and TSSs presented varying antioxidant activity in DPPH(CESs:75.69%and TSSs:83.65%),FRAP(CESs:425.39μM TE/g DW and TSSs:649.36μM TE/g DW),TBARS(CESs:42.96%and TSSs:52.16%)and O_(2)^(−)radicals scavenging(CESs:61.33%and TSSs:86.69%)*** and TSSs also exhibited antiglycation activity comparable to bovine serum albumin treated with *** addition,CESs and TSSs showed inhibition of AGE formation(34.48%and 61.85%,respectively).Antiacne activity against Cutibacterium acnes was observed with a minimum inhibitory concentration equal to minimum bactericidal concentration(CESs:36.11µg/mL and TSSs:18.34µg/mL).In photoprotective assays,CESs and TSSs showed maximum absorbance of 1.42 to 0.20 and 2.80 to 1.30,respectively,in the wavelength range of 260 to 400 ***,CESs and TSSs showed sun protection factors of 8.89 and 14.89,***:Sapindus saponaria fruit extracts show strong antioxidant potential and antiglycation activity against bovine serum albumin glycation and AGE ***,they presented antibacterial activity against Cutibacterium acnes and photoprotective effect against UV-A and UV-B.

关键词： Photoprotective AGE formation Free radical Antioxidant Triterpene saponin Sapindus saponaria

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

On the Cauchy Problem Describing an Electron-Phonon Interaction

引用

数学年刊（A辑） 2011年第4期32卷 I0001-I0004页

作者： Dias, João-Paulo Figueira, Mário oliveira, filipe Centro de Matemática e Aplicações Fundamentais and Faculdade de Ciências Universidade de Lisboa Lisboa Portugal Centro de Matemática e Aplicações Faculdade de Ciências e Tecnologia Universidade Nova de Lisboa Monte da Caparica Portugal

In this paper, a model is derived to describe a quartic anharmonic interatomic interaction with an external potential involving a pair electron-phonon. The authors study the corresponding Cauchy Problem in the semilin... 详细信息

关键词：英文摘要内容介绍编辑工作期刊

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Analysis of alternative parameters of dynamic resistance measurement in high voltage circuit breakers

引用

High Voltage 2019年第3期4卷 197-202页

作者： Herbet filipe dos Santos Sousa Adriano Costa de oliveira George Victor Rocha Xavier Henrique Nunes de Santana Edson Guedes da Costa Tarso Vilela Ferreira Federal University of Campina Grande Campina GrandeBrazil Federal University of Sergipe AracajuBrazil

Throughout its lifetime,high-voltage circuit breaker(HVCB)contacts suffer from inevitable degradation processes,especially during the formation of electric *** degraded contacts can reduce the current interruption capacity and increase the chances of operational faults,which might lead to considerable financial ***,the use of efficient evaluating techniques is a key factor to achieve systems *** dynamic resistance measurement(DRM)is a technique that can be used to evaluate the degradation level of HVCB'*** stands out from the usual technique,static resistance measurement,by allowing the assessment of both the main contacts and the arcing contacts(ACs).Usually,the mean resistance or the area under the DRM curve is used to estimate the AC ***,DRM is a non-standardised technique and there are no specified parameters to evaluate the real wear ***,an analysis of alternative parameters extractible from the DRM technique is presented in this study,such as amplitude and variance of the DRM *** results attest the possible use of more than one parameter for the continuous evaluation of HVCB ACs,characterising the DRM as a more complete and precise diagnosis tool.

关键词： resistance parameters dynamic

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

金属间化合物和低孔隙率TiC烧结体在热压下界面的扩散、挤压和反应行为(英文)

引用

稀有金属材料与工程 2012年第2期41卷 203-207页

作者：巫红燕高明霞 oliveira filipe J 朱丹潘颐 Vieira Joaquim M 浙江大学硅材料国家重点实验室 University of Aveiro Aveiro3810-193Portugal

分别以Fe40Al、Ni3Al和TiAl(NbCr)金属间化合物为基体,在一定的压力和温度下,使其和低孔隙率TiC粉体烧结体有效结合。采用扫描电镜及能谱仪等对其界面的组织结构进行分析。结果表明,所有金属间化合物均与TiC烧结体形成了冶金结合的界面... 详细信息

分别以Fe40Al、Ni3Al和TiAl(NbCr)金属间化合物为基体,在一定的压力和温度下,使其和低孔隙率TiC粉体烧结体有效结合。采用扫描电镜及能谱仪等对其界面的组织结构进行分析。结果表明,所有金属间化合物均与TiC烧结体形成了冶金结合的界面。TiC烧结体在高温保压过程中有微量分解,扩散进入了Fe40Al和Ni3Al基体表层,降低了其熔点,从而使其成为可流动状态,被挤压进入TiC烧结体的孔隙。但TiAl(NbCr)合金未能进入TiC烧结体孔隙,而是在与TiC的界面处形成了一层Ti含量高于基体约10at%的反应层。

关键词：双结构材料连接微观结构金属间化合物 TiC

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Characterization of atmospheric aerosol (PM10 and PM2.5) from a medium sized city in S?o Paulo state,Brazil

引用

Journal of Environmental Sciences 2020年第3期32卷 238-251页

作者： Bruno T.Franzin filipe C.Guizellini Diego V.de Babos Ossamu Hojo Ieda Ap.Pastre Mary R.R.Marchi Fernando L.Fertonani Cristina M.R.R.oliveira Sao Paulo State University(Unesp) Chemistry InstituteAnalytical Chemistry DepartmentAraraquaraSP14800-060Brazil Federal University of Sao Carlos-UFSCAr Chemistry DepartmentSao CarlosSP13565-905Brazil Chemistry and Environmental Sciences Department BiosciencesLanguages and Exact Sciences InstituteIbilceSaoPaulo State University(Unesp)Sao Jose do Rio PretoSP15054-000Brazil Centro de Quimica Estrutural-Faculdade de Ciencias da Universidade de Lisboa Edif.C8Campo Grande1749-016 LisboaPortugal

Air pollution causes deleterious effects on human health with aerosols being among the most polluting *** objective of this work is the characterization of the PM2.5 and PM10 aerosol mass in the *** methods of analysis include WD-XRF and *** were correlated with meteorological information and air mass trajectories(model HYSPLIT)by multivariate analysis.A morphological structural analysis was also carried out to identify the probable sources of atmospheric aerosols in the city of Sao Jose do Rio Preto,*** mean mass concentration values obtained were 24.54 μg/m^3 for PM10,above the WHO annual standard value of 20 μg/m^3 and 10.88 μg/m^3 for PM2.5 whose WHO recommended limit is10 μg/m^***-XRF analysis of the samples revealed Si and Al as major components of the coarse *** the fine fraction,the major elements were Al and *** SEM-FEG characterization allowed identifying the morphology of the particles in agglomerates,ellipsoids and filaments in the PM10,besides spherical in the *** analysis by EDS corroborated WD-XRF results,identifying the crustal elements,aluminosilicates and elements of anthropogenic origin in the coarse *** the fine fraction crustal elements were also identified;aluminosilicates,black carbon and spherical particles(C and O) originating from combustion processes were *** use of multivariate analysis to correlate air mass trajectories with the results of the morpho-structural characterization of the particulate matter allowed confirmation of the complex composition of the particles resulting from the combination of both local and long-distance sources.

关键词： Urban aerosol PM10 PM2.5 WD-XRF SEM-EDS

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Monitoring Biosignals with Low Cost Wearable Sensors

引用

Computer Technology and Application 2013年第6期4卷 323-326页

作者： filipe oliveira1 Gil Goncalves Raquel Sousa RTD Department Inovamais Matosinhos 4450 Portugal Faculty of Engineering University Porto Porto 4200 Portugal IncreaseTime Matosinhos 4450 Portugal

With the increase of aging population, we have been witnessing a decline in the quality of life influenced by numerous social, cultural and economic factors. Several studies have addressed these facts and some emerging technologies are capable of monitoring and anticipating these problems. With the advance in the development of smart textiles, it＇s possible to use these technologies in the acquisition of biosignals, which allows obtaining a better comfort regarding the use of smart clothes over traditional Ag/AgCI electrodes. In this way, it is possible to monitor for longer periods reducing the discomfort to the user. This paper reports the development of a low cost sensor with the capability of monitoring the electrical activity of the heart, measuring the heart rate and body temperature and is applied in the scenario： health ＆ wellbeing, targeting the continuous measurement of vital signs.

关键词： ECG (electrocardiogram) monitoring heart rate smart textile electrodes Ag/AgCI biosignals continuous monitoring.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Helicobacter pylori infection: Beyond gastric manifestations

引用

World Journal of Gastroenterology 2020年第28期26卷 4076-4093页

作者： Maria Luisa Cordeiro Santos Breno Bittencourt de Brito filipe Antonio França da Silva Mariana Miranda Sampaio Hanna Santos Marques Natalia oliveira e Silva Dulciene Maria de Magalhaes Queiroz Fabricio Freire de Melo Instituto Multidisciplinar em Saude Universidade Federal da BahiaVitória da Conquista 45029-094BahiaBrazil Universidade Estadual da Bahia Vitória da Conquista 45083-900BahiaBrazil Laboratory of Research in Bacteriology Faculdade de MedicinaUniversidade Federal de Minas GeraisBelo Horizonte 30130-100Minas GeraisBrazil

Helicobacter pylori(***)is a bacterium that infects more than a half of world’s *** it is mainly related to the development of gastroduodenal diseases,several studies have shown that such infection may also influence the development and severity of various extragastric *** to the current evidence,whereas this bacterium is a risk factor for some of these manifestations,it might play a protective role in other pathological *** that context,when considered the gastrointestinal tract,*** positivity have been related to Inflammatory Bowel Disease,Gastroesophageal Reflux Disease,Non-Alcoholic Fatty Liver Disease,Hepatic Carcinoma,Cholelithiasis,and ***,lower serum levels of iron and vitamin B12 have been found in patients with *** infection,leading to the emergence of anemias in a portion of *** regards to neurological manifestations,a growing number of studies have associated that bacterium with multiple sclerosis,Alzheimer’s disease,Parkinson’s disease,and Guillain-Barré***,the risk of developing cardiovascular disorders,such as atherosclerosis,is also influenced by the *** that,the ***-associated inflammation may also lead to increased insulin resistance,leading to a higher risk of diabetes mellitus among infected ***,the occurrence of dermatological and ophthalmic disorders have also been related to that *** this sense,this minireview aims to gather the main studies associating *** infection with extragastric conditions,and also to explore the main mechanisms that may explain the role of *** in those diseases.

关键词： Helicobacter pylori Extragastric Neurological Cardiovascular Autoimmune Ophthalmic Diabetes Timeline Treatment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：