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英国早产儿重症视网膜病变筛查、治疗和疗效的人群研究

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世界核心医学期刊文摘（眼科学分册） 2005年第9期1卷 1-2页

作者： Haines L. fielder a.r. Baker H. Wilkinson a.r. 陈立军 Department of Paedia.r.cs John Radcliffe Hospital University of Oxford Oxford OX3 9DU United Kingdom Prof.

Background: retinopathy of prematurity (rOP) is one of the few causes of childhood blindness in which severe vision impa.r.ent is largely preventable. Ophthalmic screening for rOPis required to identify disease that requires treatment whereby the development of potentially blinding disease can be minimised. Objectives: To make the first UK population based estimate of the incidence of babies with severe rOP(stage 3 or more); to document their clinical characteristics and management and to evaluate the appropriateness of current rOPscreening guidelines in the UK. Patients: Cases were recruited through a national surveillance programme with 1 year ophthalmic follow up and data from clinician completed questionna.r.s. results: Between 1 December 1997 and 31 March 1999, 233 preterm babies with stage 3 rOP were identified. Severity (location, extent, and presence of plus disease) was associated with degree of prematurity, most severe in the most premature babies. Fifty nine percent were treated. The UK screening protocol was followed in two thirds of cases, but in the remainder it was begun too late or was too infrequent. Three quarters of the cases were followed up at 1 year, and 13%had a severe vision deficit as a.r.sult of rOP. Conclusions: Visual deficit as a.r.sult of rOPin premature babies continues to be a severe disability in some of the survivors of neonatal intensive care. Further efforts are needed to organise treatment regionally to improve outcome and standards of practice.

关键词：视网膜病变筛查标准视力损害新生儿重症监护诊治标准卫生监测临床医生伴发病筛选标准问卷调查

Human-animal interactions and bat coronavirus spillover potential among rural residents in Southern China

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Biosafety and Health 2019年第2期1卷 84-90页

作者： Li Hongying Mendelsohn Emma Zong Chen Zhang Wei Hagan Emily Wang Ning Li Shiyue Yan Hong Huang Huimin Zhu Guangjian ross Noam Chmura Aleksei Terry Philip fielder Mark Miller Ma.r.en Shi Zhengli Daszak Peter EcoHealth Alliance New YorkNYUSA School of Education and Human Development University of Colorado DenverDenverCOUSA Key Laboratory of Special Pathogens and Biosafety Wuhan Institute of VirologyChinese Academy of SciencesWuhan 430071China School of Health Sciences Wuhan UniversityWuhan 430071China Directorate of research Business and InnovationKingston UniversityLondonUK School of Life Science Engineering and ComputingKingston UniversityLondonUK Mailman School of Public Health Columbia UniversityNew YorkNYUSA

Human interaction with animals has been implicated as a primary risk factor for several high impact zoonoses,including many bat-origin viral *** the animal-to-human spillover events that lead to emerging diseases are rarely observed or clinically examined,and the link between specific interactions and spillover risk is poorly *** investigate this phenomenon,we conducted biological-behavioral surveillance among rural residents in Yunnan,Guangxi,and Guangdong districts of Southern China,where we have identified a number of SArS-related coronaviruses in *** samples were tested for four bat-borne coronaviruses using newly developed enzyme-linked immunosorbent assays(ELISA).Survey data were used to characterize associations between human-animal contact and bat coronavirus spillover risk.A total of 1,596 residents were enrolled in the study from 2015 to *** participants(0.6%)tested positive for bat coronaviruses.265(17%)participants reported severe acute respiratory infections(SArI)and/or influenza-like illness(ILI)symptoms in the past year,which were associated with poultry,carnivore,rodent/shrew,or bat contact,with variability by family income and district of *** study provides serological evidence of bat coronavirus spillover in rural communities in Southern *** low seroprevalence observed in this study suggests that bat coronavirus spillover is a.r.re ***,this study highlights associations between human-animal interaction and zoonotic spillover *** findings can be used to support targeted biological behavioral surveillance in high-risk geographic areas in order to reduce the risk of zoonotic disease emergence.

关键词： Bat coronavirus Human-animal interaction Disease emergence Southern China rural community

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生活中永远没有错

英语沙龙（初级版） 2007年第Z1期 54-55页

作者： Brian fielder 白薇

送给邻居的圣诞节礼物,引来一封陌生人的感谢信;一个放错地方的果篮,却给一位老人送去了临终前的慰藉。

关键词：诺森伯兰

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送错的礼物

疯狂英语（阅读版） 2006年第3期 23-25页

作者： Brian fielder 李洁洁

我最近有了新变化,买了一所房子,并在七月的第一个周末搬了进去。自从搬到了新的社区,我和一些邻居相见甚欢,他们看上去都非常友好。圣诞节到了,我想给认识的邻居们表达一点心意。我坐下来数,我知道名字的或者常在院子里跟他们聊天的邻... 详细信息

我最近有了新变化,买了一所房子,并在七月的第一个周末搬了进去。自从搬到了新的社区,我和一些邻居相见甚欢,他们看上去都非常友好。圣诞节到了,我想给认识的邻居们表达一点心意。我坐下来数,我知道名字的或者常在院子里跟他们聊天的邻居有九个,我还知道他们住在哪里。

关键词：礼物门廊卡片新变化理查德上班房子圣诞节里面凯利

出生体重<1.5kg的婴儿是否需要额外长期眼科随访

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世界核心医学期刊文摘（眼科学分册） 2006年第9期2卷 34-35页

作者： O'Connor A. r. Stewart C. E. Singh J. fielder A. r. 刘瑛(译) Division of Orthoptics Thompson Yates Building University of Liverpool Liverpool L69 3GB United Kingdom 不详

Aim:To survey existing ophthalmic follow up protocols in the United Kingdom for very low birth weight(VLBW)*** addition,relative risk analysis was performed using data from a cohort study to assess which factors(birth weight,gestational age,retinopathy of prematurity(rOP)status)led to a high risk of developing amblyogenic ***:Questionna.r.s were sent to every orthoptic department in the United Kingdom(n=288)for information on their policy on the follow up of VLBW ***:responses were received from 125 departments(43%).There was a large variation in criteria used for follow up;21% of respondents using birth weight(BW)and gestational age(GA),22% using stage 3 or treated rOP,the remainder using a combination of these *** was no consensus regarding when follow up should commence(from 3 months to 3 years)or cease(1-8 years).relative risk analysis revealed that birth weight under 1500 g,GA under 33 weeks,and the presence of severe rOP were significant risk factors for developing one or more amblyogenic ***:There is no consensus on whether VLBW children need to be *** is a greatly increased risk of ophthalmic deficits in those with severe rOP or severe neurological disorders,and also in those with mild or no *** in the latter group who are not routinely followed up,have a high risk of developing treatable refractive errors and *** raises the question of whether an additional screening examination is merited.

关键词：极低出生体重儿定期随访婴儿眼科早产儿视网膜病变相对危险度队列研究方法 VLBW

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鼻颞侧不对称的早产儿性视网膜病变

美国医学会眼科杂志（中文版） 2004年第3期16卷 189-190页

作者： KieranGallagher MerrickJ.Moseley AnamikaTandon MartinP.Watson KennethD.Cocker Alista.r..fielder 齐越

目的：定量分析早产儿性视网膜病变的鼻颞侧病灶在外观上与视盘距离的不对称。

关键词：视网膜病变早产儿视盘病灶定量分析目的不对称

实验研究二维圆柱后尾流中涡脱落的有序和混沌现象

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中国科学（A辑） 1991年第10期22卷 1068-1074页

作者：魏中磊吴忠 H.E.fielder 北京大学力学系北京100871 Hermann-Fttinger Qnstitut Technische Universitǎt Berlin 1000 Berlin 12

本文给出了在re=50—400范围内二维圆柱后涡脱落的有序和混沌现象的一些初步实验结果。涡脱落由有序到混沌的转捩发生在re=184.6—193.5之间,但是它不是通过准周期途径。在涡脱落频率与re数的关系曲线上有两个间断。在re=70处的间断可... 详细信息

本文给出了在re=50—400范围内二维圆柱后涡脱落的有序和混沌现象的一些初步实验结果。涡脱落由有序到混沌的转捩发生在re=184.6—193.5之间,但是它不是通过准周期途径。在涡脱落频率与re数的关系曲线上有两个间断。在re=70处的间断可能对应于倾斜涡脱落模式的变化,在re≈193.5处的第二间断对应于由有序到混沌状态的转捩。

关键词：尾流涡旋脱落有序混沌转换

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出发、转身和触壁

游泳 2020年第1期 56-62页

作者：约翰·特伦布莱加里·菲尔德杜淑娴(译) 田纳西大学不详

你听人们说过多少次,“他出发时被人甩下一大截,不可能追回来了”,或“她输在转身上”,或“他在最后触壁时输了!”是不是听过很多次?虽然我们知道每场比赛都包括出发、转身和终点触壁环节,而且提高这些技术至关重要,但我们不是经常放松... 详细信息

你听人们说过多少次,“他出发时被人甩下一大截,不可能追回来了”,或“她输在转身上”,或“他在最后触壁时输了!”是不是听过很多次?虽然我们知道每场比赛都包括出发、转身和终点触壁环节,而且提高这些技术至关重要,但我们不是经常放松这些环节的训练标准,而把注意力放在训练其他游泳技术上吗?无论是做分解练习,还是配合游,甚至是做打腿练习,每次蹬壁出发、出发台出发、转身和触壁都是一次完善游泳技术的机会,技术才是获胜的基础。

关键词：游泳技术分解练习打腿练习转身出发注意力训练环节

早产儿视网膜病变以证据为基础的筛查标准-自然病史资料来自CrYO—rOP和LIGHT—rOP研究

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美国医学会眼科杂志（中文版） 2003年第3期15卷 182-182页

作者： JamesD.reynolds VelmaDobson GrahamE.Quinn Alista.r..fielder EarlA.Palmer richardA.Saunders robertJ.Hardy DaleL.Phelps JohnD.Baker MichaelT.Trese DavidSchaffer BettyTung 康洁

背景：早产儿视网膜病变冷冻治疗(CrYO—rOF)的多中心验证表明了阈值性rOP，治疗的有效性，并指出世界范围rOP筛查的必要性。以前的rOP筛查标准大多依据临床印象；现在我们能提出以证据为基础的筛查建议。

关键词：早产儿视网膜病变证据筛查标准自然病史冷冻治疗