检索结果-南通市图书馆

Seroepidemiology of Helicobacter pylori infection in general population in a northern Mexican city

Health 2014年第1期6卷 27-32页

作者： Cosme Alvarado-Esquivel Agar Ramos-Nevarez Sandra Margarita Cerrillo-Soto Lucio Martinez-Ramirez Carlos Alberto Guido-Arreola fernando arturo munoz-gonzalez Biomedical Research Laboratory Faculty of Medicine and NutritionJuarez University of Durango StateDurangoMexico Clinica de Medicina Familiar Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado(ISSSTE)DurangoMexico

Background: The seroepidemiology of Helicobacter pylori infection in general population in Durango City, Mexico has not been previously studied. Aims: To determine the seroprevalence of anti-H. pylori antibodies in the general population in Durango City, Mexico;and to determine socio-demographic, clinical, and behavioral characteristics of the general population associated with H. pylori seropositivity. Methods: The prevalence of anti-H. pylori IgG antibodies was examined in 345 individuals in Durango City, Mexico, using enzyme-linked immunoassays. Socio-demographic, clinical, and behavioral characteristics of the general population associated with H. pylori seroprevalence were also investigated. Results: In total, 231 (67%) of the 345 participants (mean age, 45.3. ± 17.5 years) had H. pylori IgG antibodies, 146 (63.2%) of whom had H. pylori IgG antibody levels higher than 100 U/mL. Both H. pylori seroprevalence and antibody levels increased significantly with age, and were similar in males and females. An increased H. pylori seroprevalence was found in subjects with low education and employed. In contrast, a low seroprevalence was found in subjects living in suburban areas. One of four subjects with gastritis symptoms had anti-H. pylori antibodies. The seroprevalence of H. pylori was significantly higher among women with abortion history than among those without such history. Multivariate analysis of behavioral variables showed that H. pylori seropositivity was negatively associated with raising farm animals (OR = 0.48;95% CI: 0.25-0.91;P = 0.02). Conclusions: In the general population studied, H. pylori seroreactivity increased significantly with age, not only in frequency but also in intensity. Residence, education, and occupation of the study population influenced the seropositivity rate of H. pylori.

关键词： Helicobacter pylori Seroprevalence General Population Epidemiology Mexico

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Unveiling the brain’s symphony:exploring the necessity and sufficiency of neural networks in behavior control

引用

Neural Regeneration Research 2025年第1期20卷 186-187页

作者： fernando Jose Bustos Instituto de Ciencias Biomedicas Facultad de Medicina y Facultad de Ciencias de la VidaUniversidad Andres BelloSantiagoChile Millennium Nucleus of Neuroepigenetics and Plasticity(EpiNeuro) SantiagoChile

Since the pioneering work by Broca and Wernicke in the 19th century,who examined individuals with brain lesions to associate them with specific behaviors,it was evident that behaviors are complex and cannot be fully attributable to specific brain areas ***,they involve connectivity among brain areas,whether close or *** that time,this approach was considered the optimal way to dissect brain circuitry and *** pioneering efforts opened the field to explore the necessity or sufficiency of brain areas in controlling behavior and hence dissecting brain ***,the connectivity of the brain and the mechanisms through which various brain regions regulate specific behaviors,either individually or collaboratively,remain largely *** animal models,researchers have endeavored to unravel the necessity or sufficiency of specific brain areas in influencing behavior;however,no clear associations have been firmly established.

关键词： behavior connectivity neural

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Decoding complexity: the need to enhance precision and streamline spatial understanding in neuroscience

引用

Neural Regeneration Research 2025年第3期20卷 801-802页

作者： Sameehan Mahajani Armita Salahi Brenda gonzalez Charlotte Nelson Frank Hsiung Biology&Applications Division NodexusSan JoseCAUSA

Neuroscience is the ultimate frontier in our quest for a comprehensive understanding of human behavior. Since its launch in 2009, the Human Connectome Project has emerged as a pioneering force, making heroic strides i... 详细信息

关键词： behavior frontier dating

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Inflammasome links traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease

引用

Neural Regeneration Research 2025年第6期20卷 1644-1664页

作者： Gabriela Seplovich Yazan Bouchi Juan Pablo de Rivero Vaccari Jennifer C.munoz Pareja Andrew Reisner Laura Blackwell Yehia Mechref Kevin K.Wang J.Adrian Tyndall Binu Tharakan Firas Kobeissy Department of Surgery Morehouse School of MedicineAtlantaGAUSA Department of Neurobiology Center for NeurotraumaMultiomics&Biomarkers(CNMB)Neuroscience InstituteMorehouse School of MedicineAtlantaGAUSA Department of Neurological Surgery and the Miami Project to Cure Paralysis University of Miami Miller School of MedicineMiamiFLUSA Division of Pediatric Critical Care Department of PediatricsUniversity of Miami Miller School of MedicineMiamiFLUSA Department of Pediatrics Emory UniversityAtlantaGAUSA Department of Neurosurgery Children’s Healthcare of AtlantaAtlantaGAUSA Department of Chemistry and Biochemistry Texas Tech UniversityLubbockTXUSA Morehouse School of Medicine AtlantaGAUSA

Traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease are three distinct neurological disorders that share common pathophysiological mechanisms involving neuroinflammation. One sequela of neuroinflammation includes the pathologic hyperphosphorylation of tau protein, an endogenous microtubule-associated protein that protects the integrity of neuronal cytoskeletons. Tau hyperphosphorylation results in protein misfolding and subsequent accumulation of tau tangles forming neurotoxic aggregates. These misfolded proteins are characteristic of traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease and can lead to downstream neuroinflammatory processes, including assembly and activation of the inflammasome complex. Inflammasomes refer to a family of multimeric protein units that, upon activation, release a cascade of signaling molecules resulting in caspase-induced cell death and inflammation mediated by the release of interleukin-1β cytokine. One specific inflammasome, the NOD-like receptor protein 3, has been proposed to be a key regulator of tau phosphorylation where it has been shown that prolonged NOD-like receptor protein 3 activation acts as a causal factor in pathological tau accumulation and spreading. This review begins by describing the epidemiology and pathophysiology of traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease. Next, we highlight neuroinflammation as an overriding theme and discuss the role of the NOD-like receptor protein 3 inflammasome in the formation of tau deposits and how such tauopathic entities spread throughout the brain. We then propose a novel framework linking traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease as inflammasomedependent pathologies that exist along a temporal continuum. Finally, we discuss potential therapeutic targets that may intercept this pathway and ultimately minimize long-term neurological decline.

关键词： Alzheimer's disease caspase-1 chronic traumatic encephalopathy inflammasomes neurodegeneration neuroinflammation NLRP1 NLRP3 pyroptosis tauopathy traumatic brain injury

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Environmental Factors that Affect Primary Plant Succession Trajectories on Lahars(Popocatépetl Volcano,Mexico)

引用

Journal of Mountain Science 2015年第5期12卷 1254-1266页

作者： GARCIA-ROMERO arturo ALANIS-ANAYA Rocío Marisol munoz-JIMENEZ Julio Departamento de Geografía Física Instituto de GeografíaUniversidad Nacional Autónoma de México.Circuitoexterior s/nCiudad Universitaria04510 MexicoDistrito FederalMexico Laboratorio de Análisis Geoespacial Instituto de GeografíaUniversidad Nacional Autónoma de México.Circuitoexterior s/nCiudad Universitaria04510 MexicoDistrito FederalMexico Departamento de A.G.R.y Geografía Física Facultad de Geografía e HistoriaUniversidad Complutense de Madrid.Calle Profesor Aranguren s/nCiudad Universitaria28040MadridSpain

The earliest stages of plant succession on severely disturbed sites usually follow highly unpredictable trajectories. However, in the Popocatépetl volcano area(50 km SE of Mexico City),the development of physiognomically distinct primary plant communities suggests the occurrence of various successional trajectories only 10 years after the onset of colonization of a temperate forest on lahars. To characterize plant communities and determine the environmental factors that drive the differences observed between plant communities and their successional trajectories, we monitored 64 circular sample plots(3.14 m2) from 2002 to 2011. We examined the plant communities' composition and structure in terms of their species richness and abundance, plant cover, and maximum stem height,and recorded 13 environmental factors related to the volcanic deposit characteristics, microclimate, soil,flow dynamics and gravitational processes. A cluster analysis of the species abundance data showed that,by 2011, six plant community types(CT's) had established, including grasslands, and open, dense and very dense shrub lands. As these communities developed over the same period of time and within the same overall ecosystem, then these plant community types were interpreted as different stages of the same successional trajectory. Two sequential main stages that drive regeneration were identified from this successional trajectory: a) the first four years are characterized by a steady increase in species richness and physiognomic development(plant size and coverage), mostly dominated by Baccharis conferta, Eupatorium glabratum and Senecio barbajohannis; b) from the sixth year onwards, a continued increase in the abundance of those same species led to the development of the dense shrubland *** in the availability of soil resources and disturbances linked to recent lahar flows were the main factors accounting for such differences.

关键词： Ecosystem regeneration Plantcolonization Primary succession Temperate forest Light exposure Elevation Soil Slope aspect

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Plumage brightness and uropygial gland secretions in barn swallows

引用

Current Zoology 2019年第2期65卷 177-182页

作者： Anders PAPE MOLLER fernando MATEOS-gonzalez Ecologie Systematique Evolution Universite Paris-Sud CNRS AgroParisTech Universite Paris-Saclay Batiment 362 F-91405 Orsay Cedex France Department of Ecology and Genetics Evolutionary Biology Centre University of Uppsala Norbyvagen 18d SE-75236 Uppsala Sweden

The uropygial gland has been hypothesized to play a role in sexual signaling through a "make-up" function derived from the effects of secretions from the gland on the appearanee of the plumage and bare parts of the body. Here we show that plumage brightness of dorsal feathers of individual barn swallows Hirundo rustica was greater in mated than in unmated individuals. In addition, plumage brightness in creased with colony size. Furthermore, plumage bright ness was positively correlated with the amount of wax in the uropygial gland, negatively correlated with time of sampling of uropygial wax (perhaps because more wax is present early in the morning after an entire night of wax production without any preening), and negatively correlated with the number of chewing lice that degrade the plumage. Experimentally preventing barn swallows from access to the uropygial gland reduced plumage brightness, showing a causal link between secretions from the uropygial gland and plumage brightness. These findings provide evidence consistent with a role of uropygial secretions in signaling plumage brightness.

关键词： brightness coloration preening wax sexual selection uropygial gland

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Landform Instability and Land-use Dynamics in Tropical High Mountains, Central Mexico

引用

Journal of Mountain Science 2012年第3期9卷 414-430页

作者： GARCíA-ROMERO arturo ACEVES-QUESADA José fernando ARREDONDO-LEóN Carlos Departamento de Geografía Física Instituto de Geografía Universidad Nacional Autónoma de México. Circuito exterior s/n Ciudad Universitaria 04510 Mexico Distrito Federal Mexico Unidad Académica de Estudios Regionales de la Coordinación de Humanidades Universidad Nacional Autónoma de México

This investigation is an analysis of the influence of landform instability on the distribution of land-use dynamics in a hydrographical basin, located in the Mexican Volcanic Belt mountain range (central Mexico), currently affected by substantial changes in land use and deforestation. A landform map was produced, in addition to seven attribute maps - altimetry, drainage density, slope, relief energy, potential erosion, geology and tectonics - which were considered as factors for determining landform instability through Multi-criteria Evaluation Analysis. Likewise, the direction and rhythm of land-use dynamics were analyzed in four dates - between 1976 and 2000 - and cross tabulations were made between them, in order to analyze the trends and processes of land-use dynamics. Afterwards, the databases obtained were cross tabulated with the landform variables to derive areas, percentages and correlation indices. In the study area, high-instability landforms are associated with most ancient volcanic and sedimentary landforms, where high altitude, drainage density, slope and potential to develop gravitational and fluvial processes are the major factors favouring a land-use pattern, dominated by the conservation of extensive forest land, abandonment of human land use and regeneration of disturbed areas. In contrast, low-instability landforms correspond to alluvial plains and lava hills covered by pyroclasts, where low potential erosion to develop fluvial processes, added to water and soil availability and accessibility, have favoured a land-use pattern dominated by the expansion of agroforestry plantations and human settlements, showing a marked trend towards either intensification or permanence of the current land use and with little abandonment and regeneration.

关键词： Landform instability Multi-criteriaEvaluation Analysis Land-use change and processes Tuxpan River Basin

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Molecular Determinants of Antibiotic Resistance in the Costa Rican Pseudomonas aeruginosa AG1 by a Multi-omics Approach:A Review of 10 Years of Study

引用

Phenomics 2021年第3期1卷 129-142页

作者： Jose arturo Molina-Mora fernando García Centro de Investigación en Enfermedades Tropicales(CIET)&Facultad de Microbiología Universidad de Costa RicaSan JoséCosta Rica

Pseudomonas aeruginosa AG1(PaeAG1)is a Costa Rican strain that was isolated in 2010 in a major *** strain has resistance to multiple antibiotics such asβ-lactams(including carbapenems),aminoglycosides,and ***1 is considered critical(Priority 1)due to its resistance to carbapenems,and it was the first report of a *** isolate carrying both VIM-2 and IMP-18 genes encoding for metallo-β-lactamases(MBL)enzymes(both with carbapenemase activity).Owing to these traits,we have studied this model for 10 years using diverse approaches including *** this review,we summarize the main points of the different steps that we have studied in PaeAG1:preliminary analyses of this strain at the genomic and phenomic levels revealed that this microorganism has particular features of antibiotic *** the multi-omics approach,the genome assembly was the initial step to identify the genomic determinants of this strain,includ-ing virulence factors,antibiotic resistance genes,as well as a complex accessory ***,a comparative genomic approach was implemented to define and update the phylogenetic relationship among complete *** genomes,the genomic island content in other strains,and the architecture of the two MBL-carrying ***,the proteomic profile of PaeAG1 was studied after exposure to antibiotics using 2-dimensional gel electrophoresis(2D-GE).Fourth,to study the central response to multiple perturbations in ***,i.e.,the core perturbome,a machine learning approach was *** analysis revealed biological functions and determinants that are shared by different ***,to evaluate the effects of ciprofloxacin(CIP)on PaeAG1,a growth curve comparison,differential expression analysis(RNA-Seq),and network analysis were *** the results of the core perturbome(pathways that also were found in this perturbation with CIP),it was possible to identify the“exclusive”response and determina

关键词： Pseudomonas aeruginosa PaeAG1 Antibiotic resistance Multi-omics High risk

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Parking Availability Prediction with Coarse-Grained Human Mobility Data

引用

Computers, Materials & Continua 2022年第6期71卷 4355-4375页

作者： Aurora gonzalez-Vidal fernando Terroso-Sáenz Antonio Skarmeta University of Murcia Murcia30003Spain Universidad Católica de Murcia(UCAM) Murcia30107Spain

Nowadays,the anticipation of parking-space demand is an instrumental service in order to reduce traffic congestion levels in urban *** purpose of our work is to study,design and develop a parking-availability predictor that extracts the knowledge from human mobility data,based on the anonymized human displacements of an urban area,and also from weather *** of the existing solutions for this prediction take as contextual data the current road-traffic state defined at very high temporal or spatial ***,access to this type of fine-grained location data is usually quite limited due to several economic or privacy-related *** overcome this limitation,our proposal uses urban areas that are defined at very low spatial and temporal *** conducted several experiments using three Artificial Neural Networks:Multilayer Perceptron,Gated Recurrent Units and bidirectional Long Short Term Memory networks and we tested their suitability using different combinations of *** metrics are provided for the sake of comparison within our study and between other *** solution has been evaluated in a real-world testbed in the city of Murcia(Spain)integrating an open human-mobility dataset showing high accuracy.A MAPE between 4%and 10%was reported in horizons of 1 to 3 h.

关键词： Parking space human mobility mining recurrent neural networks prediction

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Donor hepatectomy time and liver transplantation outcomes: An opportunity that cannot be dismissed

引用

World Journal of Transplantation 2024年第3期14卷 5-8页

作者： Francisca gonzalez Cohens fernando M gonzalez Web Intelligence Centre Faculty of Physics and Mathematical SciencesUniversidad de ChileSantiago 7500922Chile Department of Nephrology Faculty of MedicineUniversidad de ChileSantiago 7500922Chile

The probability of developing primary dysfunction(PD)is a function of the probability of ischemia/reperfusion(I/R)*** probability of I/R injury in turn,is a function of several donor and transplantation process variables,among which is ischemia *** et al studied the duration of a special type of warm ischemia and showed,contrary to what is known,that a longer duration is not statistically different from a shorter one in PD *** finding opens the door to the unforeseen opportunity of training fellows in performing hepatectomies,since the duration will not jeopardize liver transplant outcomes,albeit with some precautions.

关键词： Cold ischemia Warm ischemia Liver transplantation Reperfusion Primary dysfunction

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：