检索结果-南通市图书馆

Guanine-regulated proton transfer enhances CO_(2)-to-CH_(4) selectivity over copper electrode

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Catalysis 2022年第12期43卷 3101-3106页

作者： Jun Gong Jinmeng Li Chang Liu fengyuan wei Jinlong Yin Wenzheng Li Li Xiao Gongwei Wang Juntao Lu Lin Zhuang College of Chemistry and Molecular Sciences Hubei Key Laboratory of Electrochemical Power SourcesWuhan UniversityWuhan 430072HubeiChina Sauvage Center for Molecular Sciences Wuhan UniversityWuhan 430072HubeiChina The Institute for Advanced Studies Wuhan UniversityWuhan 430072HubeiChina

Electrocatalytic CO_(2) reduction has attracted growing attention as a promising route to realize artificial carbon *** transfer plays an essential role in CO_(2) reduction and dramatically impacts product ***,the precise control of proton transfer during CO_(2) reduction remains *** this study,we present a well-controlled proton transfer through the modification of several purines with similar molecular structures,and reveal a direct correlation between surface proton transfer capability and CO_(2) reduction selectivity over Cu *** a moderate proton transfer capability,the guanine modification can remarkably boost CH_(4) production and suppress C2 products ***-situ ATR-SEIRAS suggests a weakened^(*)CO intermediate adsorption and a relatively low local pH environment after the guanine modification,which facilitates the^(*)CO protonation and detachment for CH_(4) generation.

关键词： CO_(2)electroreduction Surface modification Guanine Proton transfer Methane Copper

Association between serotonin transporter gene polymorphisms and non-lesional temporal lobe epilepsy in a Chinese Han population

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2010年第16期5卷 1270-1273页

作者： fengyuan Che Youyi wei Xueyuan Heng Qingxi Fu Jianzhang Jiang Brain Department Linyi People's Hospital Linyi 276003 Shandong Province China

Serotonin （5-hydroxytryptamine, 5-HT） influences the cortical and subcortical excitatory/inhibitory balance and participates in the pathophysiological processes of epilepsy. The serotonin transporter （5-HTT） is the most important factor in serotonin inactivation. We tested whether 5-HTT polymorphisms are involved in the pathogenesis of epilepsy in Chinese Han population. We did not find a significant difference in the frequencies of genotypes and alleles in the 5-HTT gene-linked poLymorphic region （5-H-I-FLPR） in patients with non-lesional temporal lobe epilepsy and normal controls （P〉 0.05）. Frequencies of the 5-H1-1- intron 2 variable number tandem repeat （5-HTTVNTR） 12/12 genotype and allele 12 were higher in the patients with non-lesional temporal lobe epilepsy than normal controls （P 〈 0.01）. The odds ratio of affecting non-lesional temporal lobe epilepsy was 1.435 （95% Cl, 1.096 1.880） in patients carrying allele 12 （P 〈 0.05）. Although the 5-HTTLPR may not be a genetic locus of non-lesional temporal lobe epilepsy in Chinese Hart population, allele 12 in the 5-HTTVNTR may correlate with non-lesional temporal lobe epilepsy. The Stin2.12 allele and 12/12 genotype could be predisposing to non-lesional temporal lobe epilepsy.

关键词： serotonin transporter gene-linked polymorphic region serotonin transporter intron 2 variable number tandem repeat polymorphism temporal lobe epilepsy neural regeneration

Enzymatic Characterization of Pectinex XXL,a Pectinase Produced by Aspergillus niger,and Its Application in Fruit Juice Production

在线全文

学校读者我要写书评

暂无评论

现代食品科技 2024年第7期40卷 81-88页

作者： ZHU Furong LIANG Xiaomei wei Zhifu LI Li HE fengyuan CHENG Zhong College of Food and Quality Engineering Nanning UniversityNanning 530200China Guangxi Bingke Food Co.Ltd. Nanning 530100China

Pectinex XXL,a commercially prepared pectinase,was investigated for its potential application in the fruit juice *** acid was used as the substrate for determining the enzymatic properties of Pectinex XXL using the DNS *** to the results,the optimal pH for Pectinex XXL activity was 4.5,and the enzyme was stable in the pH range of 3.0~*** optimal pH and pH stability range are consistent with those of some tropical and subtropical *** optimal temperature for Pectinex XXL activity was 60℃,and the enzyme remained stable after one hour in a water bath set at 40℃.Additionally,the enzymatic activity was not inhibited in the presence of 1 mmol/L of Na^(+),Mg^(2+),Ba^(2+),Co^(2+),Zn^(2+),and Fe^(2+),whereas it was slightly inhibited in the presence of 2 mmol/L of K^(+)and Fe^(2+)and partially inhibited in the presence of 1 and 2 mmol/L of Ca^(2+)and Mn^(2+),demonstrating its good stability in acids and excellent thermal catalytic *** on the above experimental results,depectinization experiments were performed on plantain and cherry tomato juices using different amounts of Pectinex *** one hour reaction with 16 U/mL of the enzyme,the yields of the plantain and cherry tomato juices were substantially increased by 119.03%and 15.97%,respectively,while their light transmittance was remarkably enhanced by 37.65%and 12.35%,***,the enzyme reduced the viscosity of the plantain and cherry tomato juices by 88.29%and 29.50%,*** juice production experiments confirmed that this enzyme can significantly improve the yield and light transmittance of plantain juice,while effectively reducing its *** findings indicate the potential of Pectinex XXL in the industrial production of plantain juice.

关键词： plantain cherry tomato fruit juice Aspergillus niger pectinase

Clinical efficacy and identification of factors confer resistance to afatinib(tyrosine kinase inhibitor)in EGFR-overexpressing esophageal squamous cell carcinoma

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2024年第7期9卷 3130-3140页

作者： Yanni Wang Chang Liu Huan Chen Xi Jiao Yujiao Wang Yanshuo Cao Jian Li Xiaotian Zhang Yu Sun Na Zhuo Fengxiao Dong Mengting Gao fengyuan Wang Liyuan Dong Jifang Gong Tianqi Sun wei Zhu Henghui Zhang Lin Shen Zhihao Lu Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing) Department of Gastrointestinal OncologyPeking University Cancer Hospital and InstituteBeijingChina Genecast Biotechnology Co. LtdWuxiPR China State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers Beijing Key Laboratory of Carcinogenesis and Translational ResearchDepartment of Gastrointestinal OncologyPeking University Cancer Hospital and InstituteBeijingChina Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education) Department of PathologyPeking University Cancer Hospital and InstituteBeijingChina Precision Scientific(Beijing)Co. Ltd.BeijingChina Generulor Company Bio-X Lab ZhuhaiGuangdongChina Biomedical Innovation Center Beijing Shijitan HospitalCapital Medical UniversityBeijingChina Beijing Key Laboratory for Therapeutic Cancer Vaccines Beijing Shijitan HospitalCapital Medical UniversityBeijingChina

Epidermal growth factor receptor(EGFR)is reportedly overexpressed in most esophageal squamous cell carcinoma(ESCC)patients,but anti-EGFR treatments offer limited survival *** preclinical data showed the promising antitumor activity of afatinib in EGFR-overexpressing *** proof-of-concept,phase II trial assessed the efficacy and safety of afatinib in pretreated metastatic ESCC patients(n=41)with EGFR overexpression(NCT03940976).The study met its primary endpoint,with a confirmed objective response rate(ORR)of 39%in 38 efficacy-evaluable patients and a median overall survival of 7.8 months,with a manageable toxicity *** analysis of pretreatment tumors revealed that neurotrophic receptor tyrosine kinase 2(NTRK2)was negatively associated with afatinib sensitivity and might serve as a predictive biomarker,irrespective of EGFR ***,knocking down or inhibiting NTRK2 sensitized ESCC cells to afatinib *** study provides novel findings on the molecular factors underlying afatinib resistance and indicates that afatinib has the potential to become an important treatment for metastatic ESCC patients.

关键词： esophageal squamous expressing

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chan序贯平差组合算法的超宽带定位降噪

测绘通报 2023年第1期 95-100,140页

作者：董佳琪连增增徐精诚魏峰远河南理工大学测绘与国土信息工程学院河南焦作454000

在室内环境中接收机与标签之间的距离会受到随机误差的影响,针对超宽带系统的定位特性,结合Chan算法和序贯平差算法的优势,本文提出了Chan序贯平差(Chan-SA)组合算法,以削弱测距随机误差的影响。首先,通过Chan算法两次加权最小二乘获得... 详细信息

在室内环境中接收机与标签之间的距离会受到随机误差的影响,针对超宽带系统的定位特性,结合Chan算法和序贯平差算法的优势,本文提出了Chan序贯平差(Chan-SA)组合算法,以削弱测距随机误差的影响。首先,通过Chan算法两次加权最小二乘获得标签的三维坐标;然后,将此坐标作为初始值代入序贯平差算法中,利用序贯平差算法对后续数据进行迭代得出最优解。仿真数据和实地测量数据的解算结果表明:与Chan算法、粒子滤波算法和序贯平差算法比较,静态场景中Chan-SA算法定位精度分别提高50.14%、35.29%和41.91%,同时在动态场景内也证明了本文算法的适用性。因此,Chan-SA可以提高超宽带系统的定位精度和稳健性。

关键词：室内定位超宽带系统 TOA测距 Chan算法序贯平差算法

利用Geotools开源库对等高线进行批量赋值的方法研究

在线全文

学校读者我要写书评

暂无评论

测绘通报 2015年第9期 125-127,134页

作者：卢伟魏峰远河南理工大学测绘与国土信息工程学院河南焦作454003 北京博阳世通信息技术有限公司北京100101

等高线是表达地形起伏最为常用的一种方式,是GIS的基础数据模型,如果利用彩色和阴影渲染,其直观性可进一步提高。随着计算机及遥感、航空摄影的发展,很多软件(如Arc Map)都具备了地形图矢量化功能,但是通常待处理的等高线量较大,若逐条... 详细信息

等高线是表达地形起伏最为常用的一种方式,是GIS的基础数据模型,如果利用彩色和阴影渲染,其直观性可进一步提高。随着计算机及遥感、航空摄影的发展,很多软件(如Arc Map)都具备了地形图矢量化功能,但是通常待处理的等高线量较大,若逐条赋值,其效率与正确性必然受到影响。本文首先对Geotools进行了基本介绍,然后结合代码,详细阐述了利用Geotools实现对已经矢量化完毕的等高线进行批量赋值的过程。

关键词：等高线矢量化批量赋值 Geotools 几何查询

黄土高原生态系统水分利用效率演变及驱动因素空间分异规律

在线全文

学校读者我要写书评

暂无评论

水土保持研究 2022年第5期29卷 244-252页

作者：常晓格王志慧肖培青魏峰远张攀马力河南理工大学测绘与国土信息工程学院河南焦作454003 黄河水利科学研究院水利部黄土高原水土保持重点实验室郑州450003

生态系统水分利用效率(Water Use Efficiency,WUE)是碳水耦合过程的关键因子,研究黄土高原WUE时空变化及其驱动因素有助于解释生态系统对气候和水资源变化的响应机制以及水资源管理和碳预算评估。论文基于总初级生产力(Gross Primary Pr... 详细信息

生态系统水分利用效率(Water Use Efficiency,WUE)是碳水耦合过程的关键因子,研究黄土高原WUE时空变化及其驱动因素有助于解释生态系统对气候和水资源变化的响应机制以及水资源管理和碳预算评估。论文基于总初级生产力(Gross Primary Productivity,GPP)、蒸散发(Evapotranspiration,ET)、地表覆盖遥感产品和气象观测数据,利用线性斜率和偏相关系数法分析了2000-2018年黄土高原不同植被类型WUE变化趋势及其与降雨(Precipitation,P)、温度(Temperature,Temp)、饱和水汽压差(Vapor Pressure Difference,VPD)、潜在蒸散发(Potential Evaporation,ET_(0))和叶面积指数(Leaf Area Index,LAI)的偏相关性随干旱指数变化的空间分异规律。结果表明:(1)2000-2018年黄土高原多年平均WUE为1.24 gC/(m^(2)·mm),年际增长速率为0.02 gC/(m^(2)·mm·a),其中显著增加区域占47.36%。(2)黄土高原地区各植被类型年均WUE均随干旱指数增加呈显著减小趋势,草地WUE随干旱指数增加下降速率最快。同时,各植被类型WUE的变化速率均为正,但不同植被类型WUE增长速率随干旱指数的变化规律存在差异。受人类活动影响较大的农田WUE增长速率对干旱指数敏感性较低,而林草植被WUE增长速率随干旱指数增加呈先增加后减小的变化规律,存在阈值效应。(3)LAI对WUE的变化影响作用最大,其变化主导的区域占58.16%,其他驱动因素的作用大小依次为Temp,ET_(0),VPD和P。在重度干旱条件下,各植被WUE均与P均呈负相关。与农田和森林相比,灌草植被的WUE与Temp相关性对干旱指数更为敏感。另外,灌草植被的WUE与VPD和ET_(0)的相关性随干旱指数增加也存在阈值效应。

关键词：水分利用效率空间分异黄土高原偏相关分析驱动因素

维普期刊数据库博看期刊

在线全文

学校读者我要写书评

暂无评论

自动驾驶高精地图信息交互方法

武汉大学学报（信息科学版） 2024年第4期49卷 662-671,680页

作者：张焱杰黄炜刘信陶张丰源吴杭彬应申刘春同济大学城市交通研究院上海200092 同济大学测绘与地理信息学院上海200092 多伦多都会大学土木工程系加拿大多伦多M5B2K3 香港理工大学土地测量与地理信息学系中国香港九龙999077 武汉大学资源与环境科学学院湖北武汉430079

高精地图在自动驾驶应用落地的进程中发挥着重要作用,目前大多数研究着眼于高精地图中道路几何结构的高精度表征和道路静态信息的更新。然而,对路网交通中存在的大量且具有时效性的动态信息的相关研究尚有欠缺。从动态信息的内容、数据... 详细信息

高精地图在自动驾驶应用落地的进程中发挥着重要作用,目前大多数研究着眼于高精地图中道路几何结构的高精度表征和道路静态信息的更新。然而,对路网交通中存在的大量且具有时效性的动态信息的相关研究尚有欠缺。从动态信息的内容、数据结构、信息交互3个方面展开,研究高精地图动态信息。对国内外在高精地图数据组织结构和数据标准方面的工作进行整理和分析,提出了一套完整的高精地图动态信息所需涵盖的内容。将自动驾驶车辆车端和高精地图信息系统云端作为信息交互的两大主体,提出在车端、云端不同的组合模式下信息交互的方法,实现高精地图动态信息内容交互。提出的信息交互方法在局部的自动驾驶车辆与高精地图信息系统之间的交互过程中,逐步聚合到最终能够打通全域的高精地图信息数据流,实现高精地图动态信息数据的汇聚和整合,更好地服务和助力自动驾驶汽车在复杂道路环境下的导航决策能力。

关键词：高精地图自动驾驶动态信息信息交互

乙酸乙酯中可能存在的烯醇式结构与质谱结构解析

在线全文

学校读者我要写书评

暂无评论

广东化工 2018年第13期45卷 4-5,14页

作者：魏丰源武汉大学化学与分子科学学院湖北武汉430071

在合成的乙酸乙酯的粗产品中发现了一种乙酸乙酯的同分异构体,质量分数约占4%。通过GC/MS和1HNMR对该异构体的结构进行了分析,结果表明,乙酸乙酯可能存在此前未见报道的烯醇式结构。即乙酸乙酯类化合物亦可能存在类似于醛酮的烯醇式与... 详细信息

在合成的乙酸乙酯的粗产品中发现了一种乙酸乙酯的同分异构体,质量分数约占4%。通过GC/MS和1HNMR对该异构体的结构进行了分析,结果表明,乙酸乙酯可能存在此前未见报道的烯醇式结构。即乙酸乙酯类化合物亦可能存在类似于醛酮的烯醇式与酮式的互变异构。

关键词：乙酸乙酯烯醇式酮式气相色谱/质谱