检索结果-南通市图书馆

The emerging role of snoRNAs in human disease

在线全文

学校读者我要写书评

暂无评论

Genes & Diseases 2023年第5期10卷 2064-2081页

作者： Xinhai Zhang Chenglong Wang Shujun Xia Fei Xiao Jianping Peng yuxuan Gao fengbin yu Chuandong Wang Xiaodong Chen Department of Orthopedic Surgery Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine(SJTUSM)Shanghai 200092China Ultrasound Department Rui Jin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine(SJTUSM)Shanghai 200025China Department of Orthopaedic Surgery Second Hospital of Shanxi Medical UniversityTaiyuanShanxi 030001China Department of Orthopaedics The 72nd Group Army Hospital of PLAHuzhouZhejiang 313000China

Small nucleolar RNAs(snoRNAs)play critical roles in various biological processes.The aberrant expression or depletion of snoRNAs is related to various diseases.In previous research,most of the snoRNAs were categorized as C/D box snoRNAs and H/ACA box snoRNAs,whose typical functions were thought of as regulation of 2′-O-ribose methylation and pseudouridylation of ribosome RNAs,respectively.However,in the past two decades,studies have revealed an increasing number of snoRNAs without specific targets or determined cell functions.These findings indicated that some potential roles of snoRNAs are still unknown.Numerous studies have indicated the correlation of snoRNAs with human diseases.SnoRNAs play various roles in abundant biological processes,and they have great potential in controlling human diseases.This new and rising field could benefit from investigations of the disease pathogenesis,biomarker identification,and the determination of novel therapeutic targets.This review summarized the reports on snoRNAs and the regulation of different diseases in recent years.

关键词： Cancer Genetic disease Inflammation Metabolism Small nucleolar RNAs

Characterization and prediction of tailpipe ammonia emissions from in-use China 5/6 light-duty gasoline vehicles

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Environmental Science & Engineering 2024年第1期18卷 71-81页

作者： Lewei Zeng fengbin Wang Shupei Xiao Xuan Zheng Xintong Li Qiyuan Xie Xiaoyang yu Cheng Huang Qingyao Hu Yan You Ye Wu College of Chemistry and Environmental Engineering Shenzhen UniversityShenzhen 518060China State Key Laboratory of Engines Tianjin UniversityTianjin 300072China China Automotive Technology and Research Center Co.Ltd. Tianjin 300300China CATARC Automotive Test Center(Guangzhou)Co.Ltd. Guangzhou 511300China State Environmental Protection Key Laboratory of Cause and Prevention of Urban Air Pollution Complex Shanghai Academy of Environmental SciencesShanghai 200233China National Observation and Research Station of Coastal Ecological Environments in Macao Macao Environmental Research InstituteMacao University of Science and TechnologyMacao SAR 999078China School of Environment State Key Joint Laboratory of Environment Simulation and Pollution ControlTsinghua UniversityBeijing 100084China

On-road tailpipe ammonia (NH3) emissions contribute to urban secondary organic aerosol formation and have direct or indirect adverse impacts on the environment and human health. To understand the tailpipe NH3 emission characteristics, we performed comprehensive chassis dynamometer measurements of NH3 emission from two China 5 and two China 6 light-duty gasoline vehicles (LDGVs) equipped with three-way catalytic converters (TWCs). The results showed that the distance-based emission factors (EFs) were 12.72 ± 2.68 and 3.18 ± 1.37 mg/km for China 5 and China 6 LDGVs, respectively. Upgrades in emission standards were associated with a reduction in tailpipe NH3 emission. In addition, high NH3 EFs were observed during the engine warm-up period in cold-start cases owing to the intensive emissions of incomplete combustion products and suitable catalytic temperature in the TWCs. Notably, based on the instantaneous NH3 emission rate, distinct NH3–emitting events were detected under high/extra high velocity or rapid acceleration. Furthermore, NH3 emission rates correlated well with engine speed, vehicle specific power, and modified combustion efficiency, which were more easily accessible. These strong correlations were applied to reproduce NH3 emissions from China 5/6 LDGVs. The predicted NH3 EFs under different dynamometer and real-world cycles agreed well with existing measurement and prediction results, revealing that the NH3 EFs of LDGVs in urban routes were within 8.55–11.62 mg/km. The results presented here substantially contribute to improving the NH3 emission inventory for LDGVs and predicting on-road NH3 emissions in China.

关键词： NH3 instantaneous emissions Catalytic temperature Vehicle specific power Combustion efficiency Emission prediction

“被数字化”的人际关系:青年网游玩家互联网交往实践

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

当代青年研究 2022年第4期 16-24页

作者：周菲虞峰镔成都理工大学马克思主义学院南京大学社会学院

随着数字时代新媒介的出现,人们的交往形态和人际关系发生剧变。通过对网络游戏玩家的深度访谈,分析新媒体环境下数字人际关系的特征及其由弱到强的演化过程,有助于理解新媒体时代人与媒介的关系特征与互动机制。研究结果表明,网络游戏... 详细信息

随着数字时代新媒介的出现,人们的交往形态和人际关系发生剧变。通过对网络游戏玩家的深度访谈,分析新媒体环境下数字人际关系的特征及其由弱到强的演化过程,有助于理解新媒体时代人与媒介的关系特征与互动机制。研究结果表明,网络游戏中的数字人际关系呈现出活泼性、弱扩散性和独立性的特征,部分玩家借助媒介空间,沿循情感的发展线索,实现从弱关系到强关系的演化。在这一演化过程中,人们的网络交往行为深深地镶嵌在媒介所构建的环境中,人与媒介共同构成一个密不可分的数字化生存体。

关键词：数字人际关系网游玩家互联网交往媒介环境学

美国骨科开业护士与我国骨科专科护士的发展现状及启示

在线全文

学校读者我要写书评

暂无评论

中华护理杂志 2022年第10期57卷 1199-1205页

作者：黄海韵俞凤彬田蓓上海中医药大学研究生院上海市201203 上海健康医学院附属周浦医院骨科上海健康医学院附属周浦医院护理部

美国骨科开业护士发展较早、培养体系成熟,该文从美国骨科开业护士的起源与发展、准入条件与认证考核、实践范畴、培养模式、继续教育等方面分析,结合国内骨科专科护士现状,对骨科专科护士工作和培养进行综述,为国内培养应用型骨科专科... 详细信息

美国骨科开业护士发展较早、培养体系成熟,该文从美国骨科开业护士的起源与发展、准入条件与认证考核、实践范畴、培养模式、继续教育等方面分析,结合国内骨科专科护士现状,对骨科专科护士工作和培养进行综述,为国内培养应用型骨科专科护理人才提供借鉴。

关键词：骨科开业护士高级护理实践骨科专科护士综述

Quantum Spin Exchange Interactions to Accelerate the Redox Kinetics in Li–S Batteries

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2024年第5期16卷 370-383页

作者： yu Du Weijie Chen yu Wang yue yu Kai Guo Gan Qu Jianan Zhang Key Laboratory of Advanced Energy Catalytic and Functional Materials Preparation of Zhengzhou City College of Materials Science and EngineeringZhengzhou UniversityZhengzhou 450001People’s Republic of China

Spin-engineering with electrocatalysts have been exploited to suppress the“shuttle effect”in Li–S batteries.Spin selec-tion,spin-dependent electron mobility and spin potentials in activation barriers can be optimized as quantum spin exchange interactions lead-ing to a significant reduction of the electronic repulsions in the orbitals of catalysts.Herein,we anchor the MgPc molecules on fluorinated carbon nanotubes(MgPc@FCNT),which exhibits the single active Mg sites with axial displacement.According to the density functional theory calculations,the electronic spin polarization in MgPc@FCNT not only increases the adsorption energy toward LiPSs intermediates but also facilitates the tunneling process of electron in Li–S batter-ies.As a result,the MgPc@FCNT provides an initial capacity of 6.1 mAh cm^(-2) even when the high sulfur loading is 4.5 mg cm^(-2),and still maintains 5.1 mAh cm^(-2) after 100 cycles.This work provides a new perspective to extend the main group single-atom catalysts enabling high-performance Li–S batteries.

关键词： Metal phthalocyanines Spin polarization Electrocatalysis Li–S batteries

Light People:Professor Laura Na Liu

在线全文

学校读者我要写书评

暂无评论

Light(Science & Applications) 2024年第2期13卷 184-189页

作者： Hui Wang Cun yu Changchun Institute of Optics Fine Mechanics and PhysicsChinese Academy of Sciences130033ChangchunChina

Editorial The DNA nanotechnology outlines a new chapter in biological sciences,opening a new era of scientific and technological advancements.A pioneer of DNA nanotechnology,Professor Liu from the University of Stuttgart in Germany,our latest Light People,has been working at the interface,where nanophotonics meets biology and chemistry.On the path of scientific explorations.

关键词： chemistry. advancement pioneer

Macroporous Directed and Interconnected Carbon Architectures Endow Amorphous Silicon Nanodots as Low‑Strain and Fast‑Charging Anode for Lithium‑Ion Batteries

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano-Micro Letters 2024年第5期16卷 333-351页

作者： Zhenwei Li Meisheng Han Peilun yu Junsheng Lin Jie yu Guangdong Provincial Key Laboratory of Semiconductor Optoelectronic Materials and Intelligent Photonic Systems Shenzhen Engineering Lab for Supercapacitor MaterialsSchool of Material Science and EngineeringHarbin Institute of TechnologyShenzhenUniversity TownShenzhen 518055People’s Republic of China Songshan Lake Materials Laboratory Dongguan Dongguan 523808GuangdongPeople’s Republic of China Department of Mechanical and Energy Engineering Southern University of Science and TechnologyShenzhen 518055People’s Republic of China

Fabricating low-strain and fast-charging silicon-carbon composite anodes is highly desired but remains a huge challenge for lithium-ion batteries.Herein,we report a unique silicon-carbon composite fabricated by uniformly dis-persing amorphous Si nanodots(SiNDs)in carbon nanospheres(SiNDs/C)that are welded on the wall of the macroporous carbon framework(MPCF)by vertical graphene(VG),labeled as MPCF@VG@SiNDs/C.The high dispersity and amor-phous features of ultrasmall SiNDs(~0.7 nm),the flexible and directed electron/Li+transport channels of VG,and the MPCF impart the MPCF@VG@SiNDs/C more lithium storage sites,rapid Li+transport path,and unique low-strain property during Li+storage.Consequently,the MPCF@VG@SiNDs/C exhibits high cycle stability(1301.4 mAh g^(-1) at 1 A g^(-1) after 1000 cycles without apparent decay)and high rate capacity(910.3 mAh g^(-1),20 A g^(-1))in half cells based on industrial electrode standards.The assembled pouch full cell delivers a high energy density(1694.0 Wh L^(-1);602.8 Wh kg^(-1))and an excellent fast-charging capability(498.5 Wh kg^(-1),charging for 16.8 min at 3 C).This study opens new possibilities for preparing advanced silicon-carbon com-posite anodes for practical applications.

关键词： Amorphous Si nanodots Low-strain Fast-charging Lithium-ion batteries

Linear-Quadratic Pareto Cooperative Game for Mean-Field Backward Stochastic System

在线全文

学校读者我要写书评

暂无评论

Journal of Systems Science & Complexity 2024年第3期37卷 947-964页

作者： WANG yu School of Control Science and Engineering Shandong UniversityJinan 250061China

This paper focuses on a Pareto cooperative differential game with a linear mean-field backward stochastic system and a quadratic form cost functional. Based on a weighted sum optimality method, the Pareto game is equivalently converted to an optimal control problem. In the first place,the feedback form of Pareto optimal strategy is derived by virtue of decoupling technology, which is represented by four Riccati equations, a mean-field forward stochastic differential equation(MF-FSDE),and a mean-field backward stochastic differential equation(MF-BSDE). In addition, the corresponding Pareto optimal solution is further obtained. Finally, the author solves a problem in mathematical finance to illustrate the application of the theoretical results.

关键词： Backward stochastic differential equation linear-quadratic control mean-field Pareto optimality

Effect of relative humidity on the desulfurization performance of calcium-based desulfurizer

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2024年第4期138卷 179-188页

作者： Juan Lǖ yu Fu Haiyan yu HuanWang Zhe Wang Haiyan Chen School of Environment and Resource Southwest University of Science and TechnologyMianyang 621010China Guangyuan Emergency Management bureau Guangyuan 628000China

Low desulfurization efficiency impedes the wide application of dry desulfurization technology,which is a low-cost and simple process,and one significant solution is the development and manufacture of high-performance desulfurizers.In this study,firstly,a steam jet mill was used to digest quicklime;then,we utilized numerical simulation to study the flow field distribution and analyze the driving factors of quicklime digestion;and lastly,the desulfurization performance of the desulfurizer was evaluated under different relative humidities.The results show that the desulfurizer prepared via the steam jet mill had better apparent activity than traditional desulfurizers.Also,the entire jet flow field of the steam jet mill is in a supersonic and highly turbulent flow state,with high crushing intensity and good particle acceleration performance.Sufficient contact with the nascent surface maximizes the formation of slaked lime.The experiments demonstrated that the operating time with 100%desulfurization efficiency and the“break-through”time for the desulfurizer prepared via the steam jet mill is longer than that of traditional desulfurizers,and has significant advantages,especially at low flue gas relative humidity.Compared with traditional desulfurizers,the desulfurizer prepared via steam jet mill expands the range of acceptable flue gas temperature,and the failure temperature is 1.625 times that of traditional desulfurizers.This work breaks through the technical bottleneck of low dry desulfurization efficiency,which is an important step in pushing forward the application of dry desulfurization.

关键词： Dry desulfurization Relative humidity Desulfurization efficiency High-efficiency desulfurizer Quicklime digestion