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SYNTHESES　OF　Ph　AND　TEMPERATURE－SENSITIVE　HYDROGELS　AND　THEIR　APPLICATIONS　IN　CONTROLLED　RELEASE　OF　BIOMACROMOLECULES

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Chinese Chemical Letters 1995年第1期6卷 35-38页

作者： feng liu feng hua liu Guo Liang TAO Rem Xi ZHUO Department of Chemistry, Wuhan University. Wuhan. 430072 Wuhan Univ Dept Chem Wuhan 430072 Peoples R China

A series of pH- and temperature-sensitive hydrogels were prepared These gels do not swell at 37℃ and pH 1.4 but swell at 37℃ and pH 7 *** papain was loaded in these gels. it can be released at 37℃ and pH 7 4in a hi... 详细信息

关键词： Ph OF SYNTHESES TEMPERATURE APPLICATIONS AND

In vitro maturation of human oocytes maintaining good development potential for rescue intracytoplasmic sperm injection with fresh sperm

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World Journal of Clinical Cases 2022年第7期10卷 2166-2173页

作者： Yun-Qiao Dong Chuang-Qi Chen Yu-Qiang huang Dun liu Xi-Qian Zhang feng-hua liu Department of Assisted Reproductive Center Guangdong Women and Children HospitalGuangzhou 511400Guangdong ProvinceChina

BACKGROUND The outcomes of the use of commercial in vitro maturation(IVM)medium to culture immature oocytes obtained from conventional ovulation induction,followed by rescue intracytoplasmic sperm injection(RICSI),are not *** is thus difficult to widely adopt this approach in clinical ***,it is necessary to explore methods for improving the clinical outcome of *** To study the effect of sperm on the developmental potential of in vitro-matured oocytes in conventional *** This was a retrospective study of patients whose immature oocytes were harvested from conventional oocyte stimulation cycles and underwent ICSI at our hospital between June 2018 and August *** was performed using sperm collected on the day of oocyte harvest(old)and sperm collected on the day of RICSI(fresh)and oocytes matured in vitro after 24 h of culture in conventional *** rates of in vitro oocyte maturation,normal fertilization,normal cleavage,day-3 top-quality embryos,and useful blastocyst formation were compared between the two *** In total,102 germinal vesicle(GV)-stage immature oocytes were cultured in the old sperm *** the fresh sperm group,122 GV-stage immature oocytes were collected and cultured in vitro for 24 *** were no significant differences in the general conditions of males and females between the two groups(P>0.05).The oocyte maturation,normal fertilization,and normal cleavage rates of the old and fresh groups were 51.0%vs 55.7%,61.5%vs 64.7%,and 93.8%vs 93.2%,*** of the rates differed significantly(P>0.05)between the two ***,the day-3 top-quality embryo and useful blastocyst rates of the old and fresh sperm groups were 16.6%vs 63.4%;6.67%vs 34.6%,*** day-3 top-quality embryos and useful blastocyst rates of the old sperm group were significantly lower than those of the fresh group(P<0.05).CONCLUSION In vitro maturation with conventional culture medium combined with the use of

关键词： In vitro oocyte maturation Sperm injections Intracytoplasmic Semen analysis In vitro fertilization Human oocyte

A review of high-performance MEMS sensors for resource exploration and geophysical applications

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Petroleum Science 2022年第6期19卷 2631-2648页

作者： hua-feng liu Zhi-Cai Luo Zhong-Kun Hu Shan-Qing Yang Liang-Cheng Tu Ze-Bing Zhou Michael Kraft National Precise Gravity Measurement Facility(PGMF)and School of Physics Huazhong University of Science and TechnologyWuhanHubei430074China Institute of Geophysics Huazhong University of Science and TechnologyWuhanHubei430074China TianQin Research Center for Gravitational Physics and School of Physics and Astronomy Sun Yat-sen University(Zhuhai Campus)ZhuhaiGuangdong519082China Nanchang Research Institute Sun Yat-sen UniversityNanchangJiangxi330099China ESAT-MNS University of LeuvenLeuvenBelgium

MEMS sensors have the advantages of small volume,lightweight,and low cost,therefore,have been widely used in the fields of consumer electronics,industry,health,defence,and *** their ever-improving performance,MEMS sensors have also started to be used in resource exploration and geophysical ***,the requirements of high-precision MEMS sensors for geophysical applications have not been specified in ***,this paper systematically analyzes the requirements of high-performance MEMS sensors for prospecting and geophysical applications,including seismic surveillance,Earth tide,volcanic activity monitoring for natural disasters;seismic,gravity,and magnetic resource prospecting;drilling process monitoring and local gravity measurement for gravity aided *** on the above applications,this paper summarizes the state-of-the-art of research on high-performance MEMS sensors for resource exploration and geophysical *** off-the-shelf MEMS sensors have been used for earthquake monitoring,seismic exploration and drilling process monitoring,and a range of MEMS research prototype sensors have successfully been employed for Earth tides measurement and are promising to be used for gravity *** magnetometers should have a lower noise floor to meet the demand for magnetic *** gravity gradiometers are still under early development and will not be deployable in *** MEMS sensors hold the advantages of low-cost,high integration,and capability of working in extreme environments;therefore,they are likely to gradually replace some conventional geophysical instruments in some application areas.

关键词： Accelerometer Seismometer Gravimeter Tilt-meter Magnetometer

FINDINGS OF CHEST RADIOGRAPH AND SPIRAL COMPUTED TOMOGRAPHY IN SWYER-JAMES SYNDROME

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Chinese Medical Sciences Journal 2006年第1期21卷 53-56页

作者： He-shui Shi Fan Yang Ping Han Jin-long Zheng Gan-sheng feng Yong-hua liu Zhi-liang Tian Gang liu Department of Radiology Union Hospital Tongji Medical College Huazhong University of Sciences and Technology Wuhan 430022

Objective To evaluate the value of X-ray and spiral computed tomography (SCT) in the diagnosis of Swyer-James syndrome (SJS).Methods A total of 28 patients, 12 males and 16 females, were studied *** ranged from 11 to 57 years, the mean age was 32 *** patients underwent inspiratory chest X-ray films, 5 with expiratory chest films and 1 with ***, inspiratory and expiratory SCT scans were *** SCT findings were analyzed and compared with X-ray *** SCT demonstrated 56 lobes with hyperlucency and diminished *** size of 51 lobes were smaller and 5 were normal.X-ray films showed that hyperlucency was only in 29 lobes, in which 19 lobes were small-sized and the other 10 lobes *** were 56 lobes with air-trapping on expiratory SCT scans, but only 5 lobes with air-trapping on expiratory X-ray *** in 1 case demonstrated bronchiectasis and bronchiolitis *** showed 24 patients with bronchiectasis, 9 patients with tuberculosis, 10 patients with bronchiolitis, and 2 with segmental *** SCT scan is superior to chest radiography in the diagnosis and differential diagnosis of SJS.

关键词： emphysema lung computed tomography Swyer-James syndrome

A NOVEL POLYMER ENZYME LINKED IMMUNOASSAY METHOD AND ITS APPLICATIONS

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Chinese Chemical Letters 1994年第4期5卷 325-326页

作者： feng liu feng hua liu Ren Xi ZHUO Yan Zhuo DENG Yun E ZHEN (Department of Chemistry, Wuhan Univ., Wuhan 430072)

During the course of study, we found that both poly (N-isopropylacrylamide ) (PNIP) and PNIP-Ab (enzyme-labelled antibody)could be adhere tightly to a cellulose acetale-nitrate membrane, and that the retention of PNIP-Ab on the membrane increased over 30-fold when compared with the unconjugated *** we used this characteristic to develop a novel immunoassay method-polymer enzyme linked immunoassay method: homogeneous antigen-antibody reaction and heterogeneous separation process. When applied for detection of human serum HBsAg, this immunoassay system can detect as little as 1 ng/ml of human serum HBsAg.

关键词： ITS A NOVEL POLYMER ENZYME LINKED IMMUNOASSAY METHOD AND ITS APPLICATIONS

Overview and a meta-analysis of pancreatic melanoma based on case reports

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World Journal of Meta-Analysis 2014年第2期2卷 36-41页

作者： Zhan-Na Yuan feng-hua liu Yong Tang Department of Pancreatic Cancer Key Laboratory of Cancer Prevention and Therapy Tianjin Medical University Cancer Institute and Hospital Department of Gynecology Key Laboratory of Cancer Prevention and Therapy Tianjin Medical University Cancer Institute and Hospital

AIM:To investigate the clinical characteristics of pancreatic malignant ***:Here we report a case of pancreatic malignant melanoma and present a meta-analysis of pancreatic melanoma based on data from well-documented case ***:A 32-year-old male presented with abdominal pain and *** tomography showed a non-discrete mass in the head of the pancreas.A pancreatoduodenectomy was *** revealed pancreatic malignant *** showed that the neoplastic cells were positive for Melan A and S100,and that they expressed HMB-45.A review of 13 publications reporting 15 cases identified main clinical symptoms as abdominal pain(nine cases)and jaundice(three cases).Nine patients had a historyof extra-abdominal malignant *** overall median survival time was 10 ***:Pancreatic malignant melanoma is not typified by any special clinical *** diagnosis depends on biopsy or specimen *** resection remains the best treatment choice.

关键词： Pancreatic malignant melanoma Survival Diagnosis Treatment Review

Epidemiological Survey and Risk Factor Analysis of Recurrent Spontaneous Miscarriages in Infertile Women at Large Infertility Centers

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Chinese Medical Journal 2017年第17期130卷 2056-2062页

作者： Hai-Yan Wang Jie Qiao Xiao-Xi Sun Shu-Yu Wang Xiao-Yan Liang Yun Sun feng-hua liu Reproductive Medical Center Department of Obstetrics and Gynecology Peking University Third Hospital Beijing 100191 China Shanghai Ji Ai Diagnosis and Treatment Center for Genetics and Infertility Shanghai 200011 China Reproductive Medical Center Beijing Obstetrics and Gynecology Hospital Beijing 100006 China Reproductive Medical Center The Sixth Affiliated Hospital Sun Yat-sen University Guangzhou Guangdong 510665 China Reproductive Medical Center Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital Shanghai 200011 China Reproductive Medical Center Maternal and Child Health Hospital of Guangdong Province Guangzhou Guangdong 511400 China

Background：A higher frequency of spontaneous miscarriage has been observed in infertile couples,and there is a higher prevalence of infertility among patients with a history of recurrent spontaneous miscarriages （RSMs;〉2 miscarriages）.This study aimed to determine the proportion of infertile patients with RSM and examine risk factors associated in patients with RSM being treated with assisted reproductive ***：This cross-sectional observational study was conducted at six reproductive medicine centers in three cities of *** of 751 patients with at least one spontaneous miscarriage were *** data and etiological factors associated with infertility were compiled and compared between patients with a single spontaneous miscarriage （SSM） and those with ***：Two hundred （26.6%,95% confidence interval [CI]：23.50-29.95%） patients experienced RSMs and 551 （73.4%） had a single *** odds of RSM increased with increasing age （odds ratio [OR] =1.06）,uterine disorders （OR =2.09）,endocrine disorders （OR =2.48）,and immune disorders （OR =2.98）.Higher education level,masters or above,and a pelvic cavity disorder were associated with lower risk of RSM （OR =0.27 and 0.46,respectively）.Late spontaneous miscarriages were more frequent in patients with RSM than in those with a SSM （31.5% vs.14.2%,respectively,P 〈 0.001） and were associated with a history of uterine cavity procedures （OR =2.095） and cervical factors related to infertility （OR =4.136,95% CI：1.012-16.90）.Conclusions：Compared to patients with only a SSM,the conditions of patients with RSM are more *** increase the success rate of assisted reproductive technology,factors including uterus cavity adhesion,cervical relaxation,endocrine disorders,and immune disorders should be treated before assisted reproduction is *** data may provide treatment guidance for infertile patients with a history of RSM.

关键词： Assisted Reproductive Technology Epidemiological Survey Infertility Recurrent Spontaneous Miscarriage Risk Factor

A　NOVEL　POLYMER　ENZYME　LINKED　IMMUNOBLOTTING　ASSAY　METHOD　AND　ITS　APPLICATIONS（Ⅱ）

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Chinese Chemical Letters 1994年第5期5卷 387-388页

作者： feng hua liu feng liu Yan Zhuo DENG Yun E ZENG Ren Xi ZHUO (Dept. of Chem., Dept. of Anal. and Testing Scl.,Wuhan Univ., Wuhan,430072)

By using the characteristic that poly (N-isopropylacrylamide) can be adhered to callulose acetais-nitrate membrane in high retentior tightly and ramdly,we developed a novel immunoamay method- polymer enayme Hnked immu... 详细信息

关键词： ITS METHOD APPLICATIONS AND

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基于多项式拟合的抗干扰惯性系对准算法

中国惯性技术学报 2017年第5期25卷 571-575页

作者：胡华峰刘明李旦湖北航天技术研究院总体设计所武汉430040

针对包含阵风、发动机振动、人员上下车等环境下进行惯性系对准时因惯性器件偏差及外界扰动带来的比力干扰导致离散化解算对准精度差的问题,在对惯性系对准过程中的参考矢量进行了详细推导分析的基础上,提出将多项式拟合应用到惯性系对... 详细信息

针对包含阵风、发动机振动、人员上下车等环境下进行惯性系对准时因惯性器件偏差及外界扰动带来的比力干扰导致离散化解算对准精度差的问题,在对惯性系对准过程中的参考矢量进行了详细推导分析的基础上,提出将多项式拟合应用到惯性系对准中。该算法对整个对准过程中的视速度进行多项式拟合,利用拟合后的视速度代替容易受扰动引起跳变的单周期输出。仿真及测试结果表明,相比于不进行拟合的传统方案,该方案能明显提升对准精度,方位对准精度提高了7倍以上,能方便地进行工程应用,且工程应用效果好。

关键词：抗干扰惯性系多项式拟合初始对准