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The Synthesis of Dialdehyde from Sodium Hydrogen Telluride with 1,1',3,3'-Tetramethyl-2,2'-bis-benzimidazolium Salt

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Chinese Chemical Letters 2002年第9期13卷 836-838页

作者： Yue, Ke fen gu, Huan Shi, Zhen Department of Chemistry Northwest University Xi'an 710069 China

The reaction of bis-benzimidazolium salts with sodium hydrogen telluride is reported, and a new synthetic method for dialdehydes is provided.

关键词： Bis-benzimidazolium salt sodium hydrogen telluride dialdehyde synthesis.

Effect of electric acupoint stimulation on gastrointestinal hormones and motility among geriatric postoperative patients with gastrointestinal tumors

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Journal of Traditional Chinese Medicine 2016年第4期36卷 450-455页

作者： Hou Lili Xu Lei Shi Yan gu fen Department of Nursing Shanghai Pulmonary Hospital Department of Nursing Putuo HospitalShanghai University of Traditional Chinese Medicine Department of Nursing Tenth People's Hospital of Tongji University Respiratory Department Shanghai Pulmonary Hospital

OBJECTIVE:To evaluate the effects of electric acupoint stimulation on gastrointestinal hormones and motility among geriatric postoperative patients with gastrointestinal tumors,and to explore an efficient and noninvasive method for postoperative recovery of bowel ***:Forty patients were randomly and evenly assigned into a regular nursing care group(RNC) and an acupoint electric stimulation group(AES).Patients in the RNC group received regular nursing care and patients in the AES group received regular nursing care plus electric stimulation of *** serum levels of gastrin(GAS),motilin(MOT),and cholecystokinin(CCK),and an electrogastrogram(EGG) of all the patients were evaluated on the first,third,and fifth day after *** time to first flatus after surgery and the number of patients with side effects such as abdominal pain,abdominal distention,and diarrhea were ***:There were significant differences between the two groups in GAS,MOT,EGG,time to first flatus,abdominal pain,abdominal distention,and diarrhea(P < 0.05).CONCLUSION:Electric stimulation on acupoints could increase levels of GAS and MOT,promote the recovery of gastrointestinal functions,and decrease complications among postoperative senile patients with gastrointestinal tumors.

关键词： Electric stimulation therapy Aged Gas trointestinal stromal tumors Gastrointestinal hor mones Gastrointestinal motility Point ST36(Zusan li) Point ST37(Shangjuxu)

Design of a cationic accelerator enabling ultrafast ion diffusion kinetics in aqueous zinc-ion batteries

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Journal of Energy Chemistry 2025年第1期100卷 377-384页

作者： Yawei Xiao Qianqian gu Haoyu Li Mengyao Li Yude Wang National Center for International Research on Photoelectric and Energy Materials School of Materials and Energy Yunnan University Key Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources School of Chemistry and Chemical Engineering Hainan University College of Chemical Engineering Fuzhou University Yunnan Key Laboratory of Carbon Neutrality and Green Low-carbon Technologies Yunnan University

Aqueous zinc-ion batteries are highly favored for grid-level energy storage owing to their low cost and high safety,but their practical application is limited by slow ion *** address this,a strategy has been developed to create a cation-accelerating electric field on the surface of the cathode to achieve ultrafast Zn2+diffusion *** employing electrodeposition to coat MoS2on the surface of BaV6O16·3H2O nanowires,the directional built-in electric field generated at the heterointerface acts as a cation accelerator,continuously accelerating Zn2+diffusion into the active *** optimized Zn2+diffusion coefficient in CC@BaV-6O16·3H2O@MoS2(7.5×10～8cm2s-1) surpasses that of most reported V-based ***,MoS2serving as a cathodic armor extends the cycling life of the Zn-CC@BaV6O16·3H2O@MoS2full batteries to over 10000 *** work provides valuable insights into optimizing ion diffusion kinetics for high-performance energy storage devices.

关键词： Internal electric field Cationic accelerator Ion diffusion kinetics Cathode modification strategy Aqueous zinc ion battery

Pathogenesis, diagnosis, and treatment of epilepsy: electromagnetic stimulation-mediated neuromodulation therapy and new technologies

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Neural Regeneration Research 2025年第4期20卷 917-935页

作者： Dian Jiao Lai Xu Zhen gu Hua Yan Dingding Shen Xiaosong gu Academy of Medical Engineering and Translational Medicine Tianjin UniversityTianjinChina Key Laboratory of Advanced Drug Delivery Systems of Zhejiang Province College of Pharmaceutical SciencesZhejiang UniversityHangzhouZhejiang ProvinceChina Affiliated Hospital of Nantong University NantongJiangsu ProvinceChina

Epilepsy is a severe,relapsing,and multifactorial neurological *** regarding the accurate diagnosis,prognosis,and in-depth pathogenesis are crucial for the precise and effective treatment of *** pathogenesis of epilepsy is complex and involves alterations in variables such as gene expression,protein expression,ion channel activity,energy metabolites,and gut microbiota *** results are lacking for conventional treatments for *** resection of lesions,drug therapy,and non-drug interventions are mainly used in clinical practice to treat pain associated with ***-pharmacological treatments,such as a ketogenic diet,gene therapy for nerve regeneration,and neural regulation,are currently areas of research *** review provides a comprehensive overview of the pathogenesis,diagnostic methods,and treatments of *** also elaborates on the theoretical basis,treatment modes,and effects of invasive nerve stimulation in neurotherapy,including percutaneous vagus nerve stimulation,deep brain electrical stimulation,repetitive nerve electrical stimulation,in addition to non-invasive transcranial magnetic stimulation and transcranial direct current *** studies have shown that electromagnetic stimulation-mediated neuromodulation therapy can markedly improve neurological function and reduce the frequency of epileptic ***,many new technologies for the diagnosis and treatment of epilepsy are being ***,current research is mainly focused on analyzing patients’clinical manifestations and exploring relevant diagnostic and treatment methods to study the pathogenesis at a molecular level,which has led to a lack of consensus regarding the mechanisms related to the disease.

关键词： diagnosis drug treatment electroencephalography epilepsy monitoring epilepsy nerve regeneration neurostimulation non-drug interventions pathogenesis prediction

The dopaminergic system and Alzheimer's disease

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Neural Regeneration Research 2025年第9期20卷 2495-2512页

作者： Yuhan Zhang Yuan Liang Yixue gu International Medical College Chongqing Medical UniversityChongqingChina College of Pharmacy Chongqing Medical UniversityChongqingChina Department of Neurology The First Affiliated Hospital of Chongqing Medical UniversityChongqing Key Laboratory of NeurologyChongqingChina

Alzheimer's disease is a common neurodegenerative disorder in older *** its prevalence,its pathogenesis remains unclea *** addition to the most widely accepted causes,which in clude excessive amyloid-beta aggregation,tau hyperphosphorylation,and deficiency of the neurotransmitter acetylcholine,numerous studies have shown that the dopaminergic system is also closely associated with the occurrence and development of this *** is a crucial catecholaminergic neurotransmitter in the human ***-associated treatments,such as drugs that target dopamine receptor D and dopamine analogs,can improve cognitive function and alleviate psychiatric symptoms as well as ameliorate other clinical *** r,therapeutics targeting the dopaminergic system are associated with various adverse reactions,such as addiction and exacerbation of cognitive *** review summarizes the role of the dopaminergic system in the pathology of Alzheimer's disease,focusing on currently available dopamine-based therapies for this disorder and the common side effects associated with dopamine-related *** aim of this review is to provide insights into the potential connections between the dopaminergic system and Alzheimer's disease,thus helping to clarify the mechanisms underlying the condition and exploring more effective therapeutic options.

关键词： adverse drug reaction Alzheimer's disease catecholamine dopamine receptor dopamine receptor heterodimers dopaminergic system neurodegenerative disease neurotransmitter signaling pathways traditional Chinese medicine treatment

Thermodynamic assessment of Mg-Ni-Y system focusing on long-period stacking ordered phases in the Mg-rich corner

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Journal of Magnesium and Alloys 2022年第11期10卷 3250-3266页

作者： Cheng Liu Qun Luo Qin-fen gu Qian Li Kuo-Chih Chou State Key Laboratory of Advanced Special Steels&Shanghai Key Laboratory of Advanced Ferrometallurgy School of Materials Science and EngineeringShanghai UniversityShanghai 200444China Australian Synchrotron Clayton 3168Australia

The long-period stacking ordered phases(LPSOs) in Mg-Ni-Y system have been attracting great interest as effective strengthening components because of their unique structural characteristics and deformation ***,the phase relationships in LPSOs are complicated and unclear,which restricts the design of advanced magnesium-based *** aim of the present work is to experimentally determine the phase equilibria relationships focusing on LPSOs and establish the thermodynamic description for Mg-Ni-Y *** types of LPSOs,that is,14H,12R,18R and 10H,are confirmed through equilibrated alloys and high-resolution transmission electron microscopy(HR-TEM).The formation enthalpies of LPSOs(14H,12R,18R and 10H) are calculated based on density functional theories(DFT) calculations.A new ternary compound,termed as τ phase,is observed for the first time which is likely to be the distorted structure of 12R as determined from the TEM image which shows a 12-layer closed packing plane distance of 3.252nm and a shear angle of 83.2°between(0002) and(10■0) *** on the determined phase equilibria relationship,the Mg-Ni-Y system is assessed and a selfconsistent description is obtained where the LPSOs are modeled as the stoichiometric *** comparison between the calculation result and experimental data suggests the accuracy of the present thermodynamic database in the Mg-rich corner.

关键词： LPSO phases Crystal structures Phase equilibria Thermodynamics

Brain-derived neurotrophic factor plays with TRiC:focus on synaptic dysfunction in Huntington’s disease

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Neural Regeneration Research 2025年第10期20卷 2919-2920页

作者： Yingli gu Kijung Sung Chengbiao Wu Department of Neurosciences University of California San DiegoLa JollaCAUSA

Brain-derived neurotrophic factor(BDNF)exerts pleiotropic effects on brain processes including psychiatric disorders,aging,neurodegeneration,and metabolic homeostasis.A simple PubMed search using the key word“BDNF,”to date,yields over 33,000 *** fundamental biology to potential therapeutic applications,BDNF has clearly garnered extensive and significant attention in the field of neurobiology research.

关键词： Huntington homeostasis therapeutic

Transcatheter Closure of a Right Pulmonary Artery to Left Atrium Fistula Using a Ventricular Septal Defect Occluder

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Congenital Heart Disease 2021年第2期16卷 147-150页

作者： Diqi Zhu Xiaohong gu Jie Shen fen Li Department of Pediatric Cardiology Shanghai Children’s Medical Center Affiliated to Shanghai Jiaotong University School of MedicineShanghai200127China Department of Radiology Shanghai Children’s Medical Center Affiliated to Shanghai Jiaotong University School of Medicine Shanghai200127China

Background:Communication between the right pulmonary artery(RPA)and left atrium(LA)is a rare cause of central cyanosis in pediatric *** presentation:We describe a 3-year-old female patient with an oxygen saturation of 70%at *** echocardiogram indicated an abnormal color flow Doppler in the LA and she underwent standard cardiac *** angiography of pulmonary artery revealed a 7.4 mm×7.6 mm fistula between the RPA and LA and achieved successful closure using ventricular septal defect ***:The fistula between pulmonary artery and left atrium is an extremely rare but treatable congenital *** should be considered in differential diagnosis of cyanosis in children.

关键词： Transcatheter closure fistula ventricular septal defect occlude central cyanosis

Low Temperature Heat Capacity of Zn Substituted Cobalt Ferrite Nanosphere:The Relation between Magnetic Properties and Microstructure

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Journal of Wuhan University of Technology(Materials Science) 2023年第5期38卷 984-995页

作者： YUAN Meng gu Xiaojie FU Jie WANG Shaoxu SHI Quan TAN Zhicheng XU fen College of Environmental and Chemical Engineering Dalian Jiaotong UniversityDalian I16028China Thermochemistry Laboratory Dalian Institute of Chemical PhysicsChinese Academy of ScienceDalian Il6023China guangxi Key Laboratory of Information Materials(guilin University of Electronic Technology) Guilin 541000China

Co_((1-x))ZnxFe_(2)O_(4)nanospheres(x=0,0.5,0.8)with a unidirectional cubic spinel structure were prepared by a solvothermal *** using a range of theoretical and empirical models,the experimental heat capacity values were fitted as a function of temperature over a suitable temperature range to explain the possible relationship between the magnetic properties and microstructure of the *** a result,at a low temperature(T50 K),the Debye temperature decreases with increasing Zn concentration,which is due to the weakening of the interatomic bonding force after the addition of non-magnetic materials to the Co Fe_(2)O_(4)spinel ferrite.

关键词： Co-Zn spinal ferrite nanospheres magnetic properties heat capacity thermodynamic functions PPMS