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宽轴比波束双频带北斗导航天线设计

中国舰船研究 2024年第2期19卷 245-251页

作者：邓卓林尹文禄杜奋李高升湖南大学电气与信息工程学院湖南长沙410082 盲信号处理国家级重点实验室四川成都610041

[目的]为了有效拓宽北斗天线3 dB轴比波束宽度,提出一种加载寄生单元的开槽叠层微带贴片天线。[方法]通过叠层基板结构实现北斗双频带特性,并通过开槽拓宽双频段带宽,在贴片边缘切角实现双频带圆极化;同时在贴片周围加载L形寄生单元来... 详细信息

[目的]为了有效拓宽北斗天线3 dB轴比波束宽度,提出一种加载寄生单元的开槽叠层微带贴片天线。[方法]通过叠层基板结构实现北斗双频带特性,并通过开槽拓宽双频段带宽,在贴片边缘切角实现双频带圆极化;同时在贴片周围加载L形寄生单元来拓宽天线的3 dB轴比波束宽度。[结果]实测和仿真结果吻合度较高,在北斗B1和B2频段的相对带宽为3%和7.5%;3 dB轴比波束宽度可达到180°和176°;增益最高可达6 dBi。在北斗接收机试验中,天线搜星数量能达到17颗以上,定位精度在米级以内。[结论]所设计的双频带北斗导航天线具有宽轴比波束宽度和高定位精度,研究结果可为小型北斗导航天线的设计提供参考。

关键词：北斗导航天线双频带轴比波束宽度寄生单元叠层

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不同海域野生海参体壁营养成分的比较分析

食品工业科技 2024年第5期45卷 341-348页

作者：王长伟冯晓梅刘楚怡付雪媛杜芬青岛海洋生物医药研究院山东青岛266071 三奇生物医药(山东)有限公司山东日照276800 中国海洋大学医药学院山东青岛266003

探究不同海域野生海参的营养功能成分,为野生海参的综合开发利用提供参考,本文对糙刺参、黄玉参、土耳其米刺参以及冰岛红参等四种海参体壁中基本营养成分、氨基酸组成、脂肪酸组成、矿物质含量等进行检测、分析和评价。结果表明,四种... 详细信息

探究不同海域野生海参的营养功能成分,为野生海参的综合开发利用提供参考,本文对糙刺参、黄玉参、土耳其米刺参以及冰岛红参等四种海参体壁中基本营养成分、氨基酸组成、脂肪酸组成、矿物质含量等进行检测、分析和评价。结果表明,四种海参的共同点为高蛋白、低脂肪。其中,土耳其米刺参蛋白含量最高,脂肪含量最低;黄玉参的海参多糖和灰分含量均最高;冰岛红参的海参皂苷含量最高。四种海参均含有17种氨基酸,且鲜味氨基酸与药效氨基酸含量丰富;必需氨基酸含量占比13.78%~20.27%,其中冰岛红参的必需氨基酸含量最高。根据氨基酸评分(AAS)和化学评分(CS),四种海参的第一限制性氨基酸均为赖氨酸。四种海参的SFA占总脂肪酸的质量分数在23.84%~36.24%之间,均以棕榈酸(C16:0)和硬脂酸(C18:0)为主;不饱和脂肪酸占比在56.39%~72.93%之间,其中冰岛红参含量最高。在四种海参的常量元素中,除土耳其米刺参以外,其余三种海参均以钙元素含量最高,微量元素中,含量最高的均是铁元素。通过比较分析表明:不同海域野生海参富含人体需要的多种营养,具有不同的食用价值和开发利用前景。

关键词：海参营养成分氨基酸脂肪酸矿物质不同海域

中西医结合病房患者入院护理评估单的研制及信效度检验

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中华护理杂志 2024年第7期59卷 802-807页

作者：周樊华甘霖梅艳丽杜芬严冶熊莉娟华中科技大学同济医学院附属协和医院中西医结合科武汉市430022 华中科技大学同济医学院附属协和医院护理部武汉市430022

目的设计中西医结合病房患者入院护理评估单并检验其信效度。方法在文献研究的基础上,以中医学的四诊“望、闻、问、切”为基础框架,体质判别为评估结局,融入患者入院一般护理评估要点,设计中西医结合病房患者入院护理评估单初稿,采用... 详细信息

目的设计中西医结合病房患者入院护理评估单并检验其信效度。方法在文献研究的基础上,以中医学的四诊“望、闻、问、切”为基础框架,体质判别为评估结局,融入患者入院一般护理评估要点,设计中西医结合病房患者入院护理评估单初稿,采用德尔菲法对评估单初稿进行函询,修改补充后,于2022年4月选取湖北省某三级甲等综合医院中西医结合科3名临床护理人员对160例入院患者进行评估,采用Fleiss’Kappa系数和内容效度系数对评估单进行信效度检验。结果共开展2轮专家函询,问卷回收率分别为95.45%、100%。专家权威系数为0.931、0.957,肯德尔和谐系数为0.101、0.106(P<0.01)。第2轮函询专家条目重要性评分为4.13~4.82分,变异系数为0.07~0.19。最终确定的中西医结合病房患者入院护理评估单包含一般人口学资料、四诊评估及体质判别、护理风险评估3个部分,共32项评估内容。评估单的Fleiss’Kappa系数为0.602(P<0.001),条目水平内容效度指数为0.857~1.000,量表水平内容效度指数为0.920。结论编制的中西医结合病房患者入院护理评估单具有良好的信效度,能体现中医护理的内涵,适用于中西医结合病房患者的入院护理评估。

关键词：中西医结合住院患者入院护理评估单德尔菲技术信度效度

Literature review and economic evaluation of oral and intramuscular ziprasidone treatment among patients with schizophrenia in China

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General Psychiatry 2018年第6期31卷 115-121页

作者： Yu-Chen Yeh Xin Yu Congpei Zhang Wei Hao fen du Dongdong Liu Lili Yang Xin Gao Pharmerit International NewtonMassachusettsUSA Psychiatry Department Institute of Mental HealthPeking UniversityBeijingChina Psychiatry Department The First Specialized Hospital of HarbinHarbinChina Mental Health institute Second Xiangya Hospital of Central South UniversityHunanChina Pharmerit(Shanghai)Company Limited ShanghaiChina Pfizer Investment Co. LtdBeijingChina Pharmerit International BethesdaMarylandUSA

Background Over 10 million Chinese are affected by schizophrenia. The annual cost of schizophrenia in China was estimated at US$2586 per patient.Aims The study has two aims:(1) to conduct a targeted literature review of the economic literature on oral ziprasidone in China, and(2) to develop an inpatient economic model that compared the cost of intramuscular ziprasidone with other regimens including electroconvulsive therapy(ECT) for the management of acute agitation in patients with schizophrenia from a hospital's perspective in China.Methods A targeted literature review was conducted using PubMed and the Chinese literature databases for studies published between January 2007 and December2017. Studies that assessed costs associated with oral ziprasidone treatment for schizophrenia in China were summarised. In the inpatient economic model,cost measures included hospital room and board,antipsychotics,ECT and medications for the management of extrapyramidal symptoms(EPS). Input for standard antipsychotic regimens and unit cost were obtained from the literature. Hospital length of stay(LOS), utilisation of ECT and incidence of EPS were derived from the literature and supplemented/validated with a survey of psychiatrists in China. Cost was presented in 2017 Chinese yuan.Results The average estimated LOS was 29 days with ziprasidone, 33 days with risperidone+benzodiazepine,32 days with olanzapine, 35 days with haloperidol and 29 days with ECT. The cost of antipsychotics was $1260 with ziprasidone, $137 with risperidone+benzodiazepine, $913 with olanzapine and $210 with haloperidol; ECT treatment costs $785. The base-case analysis suggested that higher antipsychotic cost with ziprasidone was offset by savings with shorter LOS. Using intramuscular ziprasidone for acute management was associated with a total cost of $11157, the lowest among all antipsychotic regimens($11 424 with risperidone+benzodiazepine, $11 711 with olanzapine and $11 912 with haloperidol) and slightly higher than ECT($10 606). The cost of antipsychot

关键词： cost ziprasidone literature The ECT

流式细胞术检测药用植物基因组大小的研究策略

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医学综述 2024年第11期30卷 1292-1295页

作者：刘佩杜芬邓静怡曾蒋玲卢小舒蓝培基韶关学院广东韶关512026

流式细胞术是一种可以对悬浮于液体中微小颗粒进行分选和计数的方法。该方法的步骤包括制备完整的细胞核悬浮液、对核酸荧光染色、根据相关荧光含量分类。分析荧光标记悬液中的单细胞或其他微小颗粒信号,可以实现蛋白质含量、细胞DNA含... 详细信息

流式细胞术是一种可以对悬浮于液体中微小颗粒进行分选和计数的方法。该方法的步骤包括制备完整的细胞核悬浮液、对核酸荧光染色、根据相关荧光含量分类。分析荧光标记悬液中的单细胞或其他微小颗粒信号,可以实现蛋白质含量、细胞DNA含量、酶活性、细胞膜受体和表面抗原、细胞体积等参数的快速测定。该技术可以用于植物倍性分析和基因组大小估测等研究。目前利用流式细胞术对药用植物进行基因组大小评估的研究较少,未来有待深入研究,以期为利用流式细胞术检测基因组大小提供相关资料。

关键词：流式细胞术药用植物 C值 DNA含量

Recent Progress in Improving Rate Performance of Cellulose-Derived Carbon Materials for Sodium-Ion Batteries

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Nano-Micro Letters 2024年第8期16卷 102-147页

作者： Fujuan Wang Tianyun Zhang Tian Zhang Tianqi He fen Ran State Key Laboratory of Advanced Processing and Recycling of Non‑Ferrous Metals Lanzhou University of TechnologyLanzhou 730050People’s Republic of China School of Materials Science and Engineering Lanzhou University of TechnologyLanzhou 730050People’s Republic of China School of Mechanical and Electronical Engineering Lanzhou University of TechnologyLanzhou 730050People’s Republic of China

Cellulose-derived carbon is regarded as one of the most promising candidates for high-performance anode materials in sodium-ion batteries;however,its poor rate performance at higher current density remains a challenge to achieve high power density sodium-ion batteries.The present review comprehensively elucidates the structural characteristics of cellulose-based materials and cellulose-derived carbon materials,explores the limitations in enhancing rate performance arising from ion diffusion and electronic transfer at the level of cellulose-derived carbon materials,and proposes corresponding strategies to improve rate performance targeted at various precursors of cellulose-based materials.This review also presents an update on recent progress in cellulose-based materials and cellulose-derived carbon materials,with particular focuses on their molecular,crystalline,and aggregation structures.Furthermore,the relationship between storage sodium and rate performance the carbon materials is elucidated through theoretical calculations and characterization analyses.Finally,future perspectives regarding challenges and opportunities in the research field of cellulose-derived carbon anodes are briefly highlighted.

关键词： Cellulose Hard carbon Anode materials Rate performance Sodium-ion batteries

PEP-1-MsrA Protein Attenuated Atherogenesis in Apolipoprotein E-Deficient Mice

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PEP-1-MsrA Protein Attenuated Atherogenesis in Apolipoprotei...

JOURNAL OF ZHONGNAN UNIVERSITY OF ECONOMICS AND LAW

脂质组学与脂蛋白的新功能——第十二届全国脂质与脂蛋白学...

作者：喻红 Li MA Guanhui XIE Liang SHANG Jia CAO fen du Hong YU Department of Biochemistry and Molecular Biology Wuhan University School of Basic Medical Sciences

Background and purpose:Methionine sulfoxide reductase A(MsrA)as a specific protein disulfide reductase,has a lot of functions in redox signaling and defense against oxidative stress with reference to many diseases,however,the mechanism and function of MsrA on atherosclerosis are poor understood.The aim of this study is to investigate whether the foreign MsrA that delivered into cells,could protect against atherosclerosis in apolipoprotein E

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中南财经政法大学学报 2008年第3期 142-144页

作者：ＷＡＮＨｏｕ－ｆｅｎＤＵＰｅｎｇ

Palladium-catalyzed multi components oxy-aminofluorination and aminofluorination of gem-difluoroalkenes

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Chinese Chemical Letters 2024年第2期35卷 420-425页

作者： fen Wu Xin Li Junbiao Chang Dachang Bai State Key Laboratory of Antiviral Drugs NMPA Key Laboratory for Research and Evaluation of Innovative DrugKey Laboratory of Green Chemical Media and ReactionsMinistry of EducationSchool of Chemistry and Chemical EngineeringPingyuan LaboratoryHenan Normal UniversityXinxiang 453007China State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 200032China

Organofluorine compounds are widely used in the realm of drug discovery and material science.Herein,we developed palladium catalyzed intermolecular aminofluorination and oxy-aminofluorination of gem‑difluoroalkenes with N-fluorobenzenesulfonimide(NFSI),in which NFSI was used as the nitrogen source and oxidant.The reaction provides an efficient and straightforward synthesis route of a series ofα-trifluoromethyl benzylic amines.Notably,three/four components oxy-aminofluorination processes were realized to giveα-trifluoromethyl benzylic ether with a terminal amino group,which proceed through C(sp^(3))-O bond cleavage of easily available ether and simultaneous introduced a fluorine,an amino and an oxy substituent in one pot with excellent regioselectivity.The divergent reactivity not only included the incorporation of one ether molecular,but also much more challenged two ether insertion with excellent selectivity through succession C(sp^(3))-O bonds cleavage.This protocol allows for concise synthesis of high value amines with fluoroalkyl-substituents and selectively transformation of easily available ethers by high-valent palladium catalysis.

关键词： Palladium Multi components Aminofluorination Oxy-aminofluorination C(sp^(3))-O bond cleavage