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Possible Sources of Forecast Errors Generated by the Global/Regional Assimilation and Prediction System for Landfalling Tropical Cyclones. Part Ⅱ: Model Uncertainty

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Advances in Atmospheric Sciences 2018年第10期35卷 1277-1290页

作者： feifan ZHOU Wansuo DUAN He ZHANG Munehiko YAMAGUCHI Laboratory of Cloud-Precipitation Physics and Severe Storms Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China International Center for Climate and Environment Sciences(ICCES) Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Meteorological Research Institute of the Japan Meteorological Agency Tsukuba 305-0052Japan University of Chinese Academy of Sciences Beijing 100049China

This paper investigates the possible sources of errors associated with tropical cyclone(TC) tracks forecasted using the Global/Regional Assimilation and Prediction System(GRAPES). In Part I, it is shown that the model error of GRAPES may be the main cause of poor forecasts of landfalling TCs. Thus, a further examination of the model error is the focus of Part *** model error as a type of forcing, the model error can be represented by the combination of good forecasts and bad forecasts. Results show that there are systematic model errors. The model error of the geopotential height component has periodic features, with a period of 24 h and a global pattern of wavenumber 2 from west to east located between 60?S and 60?N. This periodic model error presents similar features as the atmospheric semidiurnal tide, which reflect signals from tropical diabatic heating, indicating that the parameter errors related to the tropical diabatic heating may be the source of the periodic model error. The above model errors are subtracted from the forecast equation and a series of new forecasts are made. The average forecasting capability using the rectified model is improved compared to simply improving the initial conditions of the original GRAPES model. This confirms the strong impact of the periodic model error on landfalling TC track forecasts. Besides, if the model error used to rectify the model is obtained from an examination of additional TCs, the forecasting capabilities of the corresponding rectified model will be improved.

关键词： GRAPES error diagnosis model uncertainty predictability tropical cyclone

BnVIR:bridging the genotype-phenotype gap to accelerate mining of candidate variations underlying agronomic traits in Brassica napus

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Molecular Plant 2022年第5期15卷 779-782页

作者： Zhiquan yang Congyuan Liang LuLu Wei Shengbo Wang feifan Yin Dongxu Liu Liang Guo Yongming Zhou Qing-Yong yang National Key Laboratory of Crop Genetic Improvement College of InformaticsHuazhong Agricultural UniversityWuhan 430070China Hubei Key Laboratory of Agricultural Bioinformatics College of InformaticsHuazhong Agricultural UniversityWuhan 430070China

Dear Editor,Genetic variations,which range from single nucleotide polymor-phisms(SNPs)and short insertion/deletions(InDels)to large-scale structural variations(SVs),are the basis of phenotypic *** the effect of geneti... 详细信息

关键词： agronomic traits InDel

SINGLE CELL IMAGING OF BAX TRANSLOCATION DURING APOPTOSIS INDUCED BY PHOTOFRIN-PDT

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Journal of Innovative Optical Health Sciences 2009年第2期2卷 209-214页

作者： feifan ZHOU DA XING WEI R.CHEN MOE Key Laboratory of Laser Life Science&Institute of Laser Life Science South China Normal University Guangzhou 510631China Department of Engineering and Physics College of Mathematics and Science University of Central OklahomaEdmondOklahoma 73034USA

Apoptosis is an important cellular event that plays a key role in the therapy of many *** mechanism of the initiation and regulation of photodynamic therapy(PDT)–induced apoptosis is *** previous study found that Photofrin was localized primarily in mitochondria,the primary targets of *** key role of Bax in the mitochondria-mediated apoptosis has been demonstrated in many *** order to determine the role of Bax in the mitochondrion-mediated apoptosis induced by Photofrin-PDT,we used the GFP-Bax plasmid to monitor the dynamics of Bax activation after PDT *** laser scanning confocal microscopy,we found that Bax did not translocate from the cytosol to mitochondria when the mitochondrial membrane potential(∆Ψm)disappeared,measured by ***,for Photofrin-PDT,the commitment to cell death is independent of Bax activation.

关键词： Photofrin-photodynamic therapy mitochondria-mediated apoptosis Bax activation translocation.

工况参数对双列角接触轮毂轴承单元温度分布的影响

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轴承 2025年第1期 82-87页

作者：马亚飞董艳方邱明何恺陈非凡河南科技大学机电工程学院河南洛阳471003 机械装备先进制造河南省协同创新中心河南洛阳471003

为研究影响双列角接触轮毂轴承单元温度分布的关键因素,基于光纤传感的波分复用技术实现轮毂轴承单元外圈12个测温点的分布式测温试验,并将试验数据与灰色关联度模型结合,对影响轮毂轴承单元温度分布的因素进行分析排序。试验结果表明:... 详细信息

为研究影响双列角接触轮毂轴承单元温度分布的关键因素,基于光纤传感的波分复用技术实现轮毂轴承单元外圈12个测温点的分布式测温试验,并将试验数据与灰色关联度模型结合,对影响轮毂轴承单元温度分布的因素进行分析排序。试验结果表明:各列各测点温度出现明显的分化现象,右列温升高于左列且右列测点温度离散性更大;联合载荷工况下,工况参数对轴承左列平均温升、右列平均温升、平均温升、轴向温差、左列周向温差、右列周向温差的影响程度从大到小排序均为转速、轴向力、径向力。

关键词：滚动轴承轮毂轴承单元灰色关联分析温升试验温度载荷转速

Oocyte TET3: an epigenetic modifier responsible for maternal inheritance of glucose intolerance

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Signal Transduction and Targeted Therapy 2022年第11期7卷 3985-3986页

作者： Xiaoxue Jiang Fei Xiao feifan Guo Jinshan Hospital State Key Laboratory of Medical NeurobiologyInstitute for Translational Brain ResearchMOE Frontiers Center for Brain ScienceFudan UniversityShanghaiChina

In a recent paper published in Nature,Chen et *** a new perspective on how glucose tolerance of the offspring is affected by pregestational hyperglycaemia.1 They showed that oocytes isolated from hyperglycemic mice transmit the impaired glucose homeostasis to the offspring via epigenetic modifications,and insufficiency of oocyte TET3 dioxygenase is indispensable for this process.

关键词： epigenetic impaired homeostasis

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甘草类制剂不良反应及其机制研究进展

药物评价研究 2018年第7期41卷 1363-1368页

作者：武媛媛顾坤高茜茜杨非凡刘传鑫李遇伯范思邈天津中医药大学中药学院天津300193

近年来中药及其制剂的安全用药备受国内外学者的关注。综述了甘草酸苷注射液、复方甘草口服液、复方甘草片等甘草类制剂不良反应的研究进展,从其引发的内分泌、心血管、神经、生殖、消化、免疫等多个系统的不良反应进行总结阐述,其中主... 详细信息

近年来中药及其制剂的安全用药备受国内外学者的关注。综述了甘草酸苷注射液、复方甘草口服液、复方甘草片等甘草类制剂不良反应的研究进展,从其引发的内分泌、心血管、神经、生殖、消化、免疫等多个系统的不良反应进行总结阐述,其中主要涉及到的作用机制包括雌激素样作用、糖皮质激素样作用、盐皮质激素样作用等,希望能够指导甘草及其制剂在临床上的合理使用。

关键词：甘草酸苷制剂甘草酸苷药物不良反应安全用药

Classification and Spatial Pattern of Rural Multifunction from the Diversify of Construction Land Use:Taking Tongshan District of Jiangsu Province as a Case Study

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Chinese Geographical Science 2023年第5期33卷 865-879页

作者： MA Xiaodong SUN Xinzhe ZHEN Yu JIAO feifan LI Xin School of Geography Geomatics&PlanningJiangsu Normal UniversityXuzhou 221116China Construction of Characteristic Towns and Villages and Research Base of Land Management Jiangsu Normal UniversityXuzhou 221116China School of Public Management China University of Mining and TechnologyXuzhou 221116China

The development of rural area in suburban(RAS)is comprehensively influenced by the mixed processes of non-farming,local urbanization and rural industrialization and has distinctive multifunctional features on the socioeconomic and resource *** reconstruction in the RAS is mainly manifested by changes in the quantity and structure of the construction land use(CLU).We took Tongshan District of Jiangsu Province as the study *** the logic of identifying,clustering,and diagnosing,we assessed the functional features of CLU and analyzed the differentiation of the scale and structure of CLU in RAS,with the aim of identifying the types and characteristics of multifunctional development in these *** study found that:1)typical RAS were experiencing multifunctional space reconstruction,and their multifunctional value was emerging and *** CLU was rapidly expanding,and the types of CLU were evolving from single to multiple uses;2)based on the dominant function of diverse rural CLU,we classified RAS into five types,dominated by the following functions,respectively:commercial services,industrial production,residential living,basic support and public service;3)according to the dominant function and spatial pattern,the development types of RAS were classified into agricultural service,comprehensive services,and integrated industries service,showing a circular spatial pattern from the suburbs to distant *** results can provide policy implication by creating new development impetus from rural multifunction perspective to promote the RAS revitalization.

关键词： rural area in suburban rural multifunction construction land use development type Jiangsu Province

Effect of vegetation of transgenic Bt rice lines and their straw amendment on soil enzymes, respiration, functional diversity and community structure of soil microorganisms under field conditions

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Journal of Environmental Sciences 2012年第7期24卷 1259-1269页

作者： Hua Fang Bin Dong Hu Yan feifan Wang Baichuan Wang Yunlong Yu Institute of Pesticide and Environmental Toxicology College of Agriculture and BiotechnologyZhejiang UniversityHangzhou 310058China Key Laboratory of Molecular Biology of Crop Pathogens and lnsects Ministry of Agriculturel-langzltou JlO038China 3.Agricultural Service CenterQiduWujiang 215234China Agricultural Service Center QiduWujiang 215234China

With the development of transgenic crops, there is an increasing concern about the possible adverse effects of their vegetation and residues on soil environmental quality. This study was carried out to evaluate the possible effects of the vegetation of transgenic Bt rice lines Huachi B6 （HC） and TT51 （TT） followed by the return of their straw to the soil on soil enzymes （catalase, urease, neutral phosphatase and invertase）, anaerobic respiration activity, microbial utilization of carbon substrates and community structure, under field conditions. The results indicated that the vegetation of the two transgenic rice lines （HC and TT） and return of their straw had few adverse effects on soil enzymes and anaerobic respiration activity compared to their parent and distant parent, although some transient differences were observed. The vegetation and subsequent straw amendment of Bt rice HC and TT did not appear to have a harmful effect on the richness, evenness and community structure of soil microorganisms. No different pattern of impact due to plant species was found between HC and TT. It could be concluded that the vegetation of transgenic Bt rice lines and the return of their straw as organic fertilizer may not alter soil microbe-mediated functions.

关键词： anaerobic respiration enzyme activity functional diversity community structure transgenic Bt rice

Stimuli-responsive coordination polymers toward next-generation smart materials and devices

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eScience 2024年第3期4卷 1-31页

作者： feifan Lang Jiandong Pang Xian-He Bu School of Materials Science and Engineering Smart Sensing Interdisciplinary Science CenterTKL of Metal and Molecule-Based Material ChemistryCollaborative Innovation Center of Chemical Science and EngineeringNankai UniversityTianjin 300350China State Key Laboratory of Elemento-Organic Chemistry College of ChemistryNankai UniversityTianjin 300071China Haihe Laboratory of Sustainable Chemical Transformations Tianjin 300192China State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhouFujian 350002China

Stimuli-responsive coordination polymers(CPs)are among one of the most prolific research areas in developing the next-generation functional *** capability of being accurately excited by particular external changes with pre-determined and observable/characterizable behaviors correspond,are the so called“stimuli”and“responsive”.Abundant types of CP compounds,especially metal-organic frameworks(MOFs),are of rocketing interest owing to their compositional diversity,structural tunability,and in essence their highly engineerable *** present review is aimed to sketch several common types of stimulation and the corresponding responses for CPs,accompanied with the broad logic and mechanisms *** further from the aspect of material revolution,some representative progresses together with the latest advances of CP-based materials in various fields are covered in attempt to display a broader picture towards the possible prospects of this topic.

关键词： Coordinationpolymers Metal-organicframeworks Stimuli-responsive Smart materials