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Massive Preparation of Coumarone-indene Resin-based Hyper-crosslinked Polymers for Gas Adsorption

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Chinese Journal of Polymer Science 2018年第10期36卷 1168-1174页

作者： Ke Tian Ting-Ting Zhu Ping Lan Zheng-Chen Wu Wei Hu fei-fei xie Lei Li College of Materials and Fujian Provincial Key Laboratory of Materials Genome Xiamen University Material and Textile College Jiaxing University

Hyper-crosslinked polymers （HCPs） are promising materials for gas capture and storage because of their low cost and easy preparation. In this work, we report the massive preparation of coumarone-indene resin-based hyper-crosslinked polymers via one-step Friedel-Crafts alkylation. Low-cost coumarone-indene resin serves as the new building block and chloroform is employed as both solvent and external crosslinker. A maximum surface area of 966 m2·g-1 is achieved, which is comparable with that of previously-reported coal tar-based porous organic polymers. Most importantly, a large number of heteroatoms including inherent oxygen atoms and introduced chlorine atoms in obtianed HCPs further enhance the interaction between specific sorbate molecule and adsorbent. Therefore, optimal structural and chemical property endow the new coumarone-indene resin-based HCPs with decent gas storage capacity （14.60 wt% at 273 K and 0.1 MPa for CO2; 1.18 wt% at 77.3 K and 0.1 MPa for H2）. These results demonstrate that new HCPs are potential candidates for applications in CO2 and H2 capture.

关键词： Coumarone-indene resin Friedel-Crafts alkylation Gas adsorption Microporous organic polymers

Significance of serum glucagon-like peptide-1 and matrix Gla protein levels in patients with diabetes and osteoporosis

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World Journal of Clinical Cases 2022年第5期10卷 1527-1535页

作者： fei-fei xie Yu-Fang Zhang Yan-Fang Hu Yun-Yun xie Xiao-Ying Wang Shu-Zhen Wang Bao-Qiang xie Department of Endocrinology Guangdong Provincial People’s Hospital Ganzhou Hospital(Ganzhou Municipal Hospital)Ganzhou 341000Jiangxi ProvinceChina

BACKGROUND Osteoporosis is a systemic bone disease characterized by decreased bone mass,impaired bone mass,and reduced bone strength that leads to increased bone fragility and *** 2 diabetes mellitus(T2DM)complicated with osteoporosis is a common systemic metabolic bone disease,and reduced bone mass and bone strength are considered the main clinical features;however,the pathogenesis of this disease has not been fully *** occurrence is considered related to sex,age,and genetic *** are many risk factors for diabetes complicated with ***,exploring these risk factors will help prevent *** To investigate the relationships among serum glucagon-like peptide-1(GLP-1)levels,matrix Gla protein(MGP)levels,and diabetes with *** Sixty patients with T2DM complicated with osteoporosis confirmed by the endocrinology department of our hospital were selected as the case *** T2DM patients with bone loss were selected as the control *** healthy participants were selected as the healthy *** general data,bone mineral density index,and bone metabolic markers of the three groups were *** relationships among GLP-1 levels,MGP levels,and the bone mineral density index of the case group were analyzed using linear correlation analysis and a logistic regression *** Differences in sex,smoking,and drinking among the case group,control group,and healthy group were not statistically significant(P>0.05).The mean age of the case group was older than those of the control and healthy groups(P<0.05).The body mass index,fasting plasma glucose level,HbA1c level,hypertension rate,and coronary heart disease rate of the case and control groups were higher than those of the healthy group(P<0.05).The serum GLP-1 and MGP levels of the case group were lower than those of the control and healthy groups;these differences were statistically significant(P<0.05).The serum GLP-1 and MGP levels of the control gr

关键词： Glucagon-like peptide-1 Matrix Gla protein Diabetes mellitus Osteoporosis Bone mineral density Systemic bone disease

Streptococcus anginosus in the development and treatment of precancerous lesions of gastric cancer

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World Journal of Gastrointestinal Oncology 2024年第9期16卷 3771-3780页

作者： Su-Ting Qian Hao-Yu Zhao fei-fei xie Qing-Sheng Liu Dan-Li Cai Department of Digestive Hangzhou Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical UniversityHangzhou 310007Zhejiang ProvinceChina Science and Education Section Hangzhou Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical UniversityHangzhou 310007Zhejiang ProvinceChina Intensive Care Unit The First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine)Hangzhou 311122Zhejiang ProvinceChina

The microbiota is strongly association with *** have shown significant differences in the gastric microbiota between patients with gastric cancer(GC)patients and noncancer patients,suggesting that the microbiota may play a role in the development of *** Helicobacter pylori(***)infection is widely recognized as a primary risk factor for GC,recent studies based on microbiota sequencing technology have revealed that *** microbes also have a significant impact on GC.A recent study discovered that Streptococcus anginosus(***)is more prevalent in the gastric mucosa of patients with GC than in that of those without *** infection can spontaneously induce chronic gastritis,mural cell atrophy,mucoid chemotaxis,and heterotrophic hyperplasia,which promote the development of precancerous lesions of GC(PLGC).*** also disrupts the gastric barrier function,promotes the proliferation of GC cells,and inhibits ***,*** is underrepresented in the *** reports suggest that it may cause precancerous lesions,indicating its emerging *** novel molecular diagnostic techniques,such as polymerase chain reaction,genetic testing,and Ultrasensitive Chromosomal Aneuploidy Detection,can be used to gastric precancerous lesions via microbial ***,we present a concise summary of the relationship between *** and *** aim was to further investigate new methods of preventing and treating PLGC by exploring the pathogenicity of *** on PLGC.

关键词： Streptococcus anginosus Gastric cancer Precancerous lesions of gastric cancer Microbiota Microbiota sequencing technology

Prospects in the application of ultrasensitive chromosomal aneuploidy detection in precancerous lesions of gastric cancer

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World Journal of Gastrointestinal Surgery 2024年第1期16卷 6-12页

作者： Su-Ting Qian fei-fei xie Hao-Yu Zhao Qing-Sheng Liu Dan-Li Cai Department of Digestive Hangzhou Hospital of Traditional Chinese MedicineHangzhou 310007Zhejiang ProvinceChina Science and Education Section Hangzhou Hospital of Traditional Chinese MedicineHangzhou 310007Zhejiang ProvinceChina Intensive Care Unit The First Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhou 311122Zhejiang ProvinceChina

Gastric cancer(GC)is a prevalent malignant tumor within the digestive system,with over 40%of new cases and deaths related to GC globally occurring in *** advancements in treatment modalities,such as surgery supplemented by adjuvant radiotherapy or chemotherapeutic agents,the prognosis for GC remains *** targeted therapies and immunotherapies are currently under invest-igation,but no significant breakthroughs have been *** have indicated that GC is a heterogeneous disease,encompassing multiple subtypes with distinct biological characteristics and ***,personalized treatment based on clinical features,pathologic typing,and molecular typing is crucial for the diagnosis and management of precancerous lesions of gastric cancer(PLGC).Current research has categorized GC into four subtypes:Epstein-Barr virus-positive,microsatellite instability,genome stability,and chromosome instability(CIN).Technologies such as multi-omics analysis and gene sequencing are being employed to identify more suitable novel testing methods in these *** these,ultrasensitive chromosomal aneuploidy detection(UCAD)can detect CIN at a genome-wide level in subjects using low-depth whole genome sequencing technology,in conjunction with bioinformatics analysis,to achieve qualitative and quantitative detection of chromosomal *** editorial reviews recent research advancements in UCAD technology for the diagnosis and management of PLGC.

关键词： Gastric cancer Precancerous lesions of gastric cancer Molecular typing Ultrasensitive chromosomal aneuploidy detection Adjuvant therapy Application prospects

Therapeutic efficacy of immunotherapy for gastric cancer metastasis

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World Journal of Gastrointestinal Surgery 2024年第12期16卷 3881-3886页

作者： fei-fei xie Su-Ting Qian Hao-Yu Zhao Qing-Sheng Liu Department of Digestive Hangzhou Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical UniversityHangzhou 310007Zhejiang ProvinceChina Science and Education Section Hangzhou Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical UniversityHangzhou 310007Zhejiang ProvinceChina

Gastric cancer(GC)metastasis is the main cause of poor prognosis for GC *** recent years,breakthroughs in immunotherapy have been made in the treatment of many kinds of cancers,providing new hope for patients with GC *** paper reviews the mechanism of immunotherapy in GC meta-stasis and its clinical application,and discusses and compares the research and efficacy of immunotherapy in patients with liver metastasis,lung metastasis,peritoneal metastasis and lymph node metastasis of *** study explores the challenges and future development directions of immunotherapy,and provides a theoretical basis and clinical guidance for the precise treatment of patients with GC metastasis.

关键词： Gastric cancer Metastasis Immunotherapy Liver metastasis Lung metastasis Peritoneal metastasis

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肺癌患者术后康复自我效能感影响因素研究

中华护理教育 2017年第8期14卷 610-614页

作者：黄菲菲张娟谢莉张静平福建医科大学护理学院福州市350108 南京军区福州总医院福建省立医院中南大学湘雅护理学院护理心理学研究中心

目的探讨肺癌患者术后康复自我效能感的现状,并分析其影响因素,为进一步规范肺癌患者术后康复相关措施的制订提供参考。方法采用一般资料调查表和肺癌患者术后康复管理自我效能感测评量表,对福州市5所三级甲等医院的238例肺癌术后患者... 详细信息

目的探讨肺癌患者术后康复自我效能感的现状,并分析其影响因素,为进一步规范肺癌患者术后康复相关措施的制订提供参考。方法采用一般资料调查表和肺癌患者术后康复管理自我效能感测评量表,对福州市5所三级甲等医院的238例肺癌术后患者进行调查。结果肺癌患者术后康复管理自我效能感得分为(109.77±14.04)分,多元线性回归分析结果显示,患者入院次数、文化程度、负性情绪、应对方式、社会支持、主观幸福感和创伤后成长是肺癌患者术后康复自我效能感的影响因素,可解释40.1%的变异。结论肺癌患者术后康复管理自我效能感水平有待提高;临床医护人员在健康教育及护理干预时要注重患者社会支持系统的建立,改善其主观幸福感,进一步提高其生活质量。

关键词：肺肿瘤康复自我效验

Bimetallic water oxidation: One-site catalysis with two-sites oxidation

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Journal of Energy Chemistry 2021年第12期30卷 1-7,I0001页

作者： fei xie Ming-Tian Zhang Center of Basic Molecular Science(CBMS) Department of ChemistryTsinghua UniversityBeijing 100084China

Water oxidation is the key half reaction to achieve full splitting of water to hydrogen and ***,a binuclear complex,[(L^(4-))Co_(2)~Ⅲ(OH)]ClO_(4),was reported as a stable and efficient homogenous catalyst for electrocatalytic water oxidation in 0.1 M phosphate buffer(pH 7.0).Cyclic voltammetry experiments indicated that the catalytic process proceed via "one-site catalysis with two-sites oxidation" mechanism in which both two metal sites store the required oxidation equivalents for water oxidation and O-O bond formation occurs by single-site water nucleophilic attack(WNA).

关键词： Water oxidation Bimetallic catalysis O-O bond formation Cobalt catalyst Oxygen evolution

新生儿先天性巨结肠的X线诊断(附33例报告)

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实用放射学杂志 2008年第6期24卷 830-832页

作者：王克明孙洁林飞飞谢娜赵彩蕾徐大勇向葵深圳市儿童医院放射科深圳市儿童医院放射科广东深圳518026

目的探讨钡剂灌肠、腹部平片对新生儿先天性巨结肠X线诊断的价值。方法搜集经手术证实、病理诊断的新生儿先天性巨结肠33例,分析钡剂灌肠、腹部平片典型的及不典型的X线表现,对所得的结果进行回顾性地研究。结果本组33例新生儿中,钡剂... 详细信息

目的探讨钡剂灌肠、腹部平片对新生儿先天性巨结肠X线诊断的价值。方法搜集经手术证实、病理诊断的新生儿先天性巨结肠33例,分析钡剂灌肠、腹部平片典型的及不典型的X线表现,对所得的结果进行回顾性地研究。结果本组33例新生儿中,钡剂灌肠发现为先天性巨结肠短段型1例,常见型16例,长段型2例,全结肠型5例;24 h随访钡剂潴留于整个结肠5例,部分结肠21例;直肠、乙状结肠不规则锯齿状改变2例。腹部平片表现为结肠低位不完全性梗阻及肠淤张20例;肠气偏少5例。结论运用钡剂灌肠、腹部平片等方法,检查临床初诊为先天性巨结肠的新生儿,可以提供很有价值的X线诊断。

关键词：新生儿先天性巨结肠钡剂灌肠 X线摄影

Serum zinc level is associated with liver dysfunction caused by white smoke inhalation

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Gastroenterology Report 2018年第4期6卷 304-307,I0002页

作者： fei xie Lixin xie Department of Pulmonary and Critical Care Medicine Chinese PLA General HospitalBeijingChina

Background:White smoke bomb exposure in the military setting could result in organ injuries,which is uncommon and has been rarely described in previous *** aim of this study is to observe whether serum zinc levels are associated with liver function after white smoke ***:Fifteen patients with white smoke exposure were the subjects in this *** clinical manifestations,liver function tests and the serum zinc levels were ***:The level of serum zinc was increased in the moderate or severe group(n=4)compared with that in the mild group(n=11).The four cases in the moderate or severe group had delayed impairment of liver function with an elevation of alanine ***,increased blood concentrations of hyaluronic acid were found in three patients in the moderate or severe *** no hexachloroethane or trichloropropane was ***:This study suggested that serum zinc levels may be associated with the severity of liver injuries after white smoke inhalation.

关键词： Zinc chloride smoke inhalation injury liver function