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International Journal of Minerals,Metallurgy and Materials 2013年第12期20卷 1208-1213页

作者： Ye Wang Qing-zhi Yan fei-fei zhang Chang-chun Ge Xiao-lu zhang Hai-qin Zhao Laboratory of Special Ceramics and Powder Metallurgy University of Science and Technology Beijing Beijing Railway Star Fortune Technology Co. Ltd. CSR Qingdao Sifang Locomotive & Rolling Stock Co. Ltd.

Copper matrix composites consisting of chromium （Cr） or ferrochrome （Cr-Fe） as strengthening elements and molybdenum disulfide as a lubricant had been sintered in nitrogen and hydrogen atmosphere, respectively. Their morphology and energy-dispersive X-ray spectrometry （EDS） analysis showed that serious interaction occurred between MoS2 and Cr （or Cr-Fe） particles when the samples were sintered in hydrogen atmosphere. Chromium sulfide compound （CrxSy） was formed as a reaction product, which decreased the density and strength of the composites remarkably. This interaction was inhibited when the samples were sintered in nitrogen atmosphere; thus, the mechanical properties of the composites were improved.

关键词： metallic matrix composites microstructure mechanical properties chromium ferrochrome sintering

Metastasis-associated long noncoding RNAs in gastrointestinal cancer: Implications for novel biomarkers and therapeutic targets

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World Journal of Gastroenterology 2016年第39期22卷 8735-8749页

作者： fei-fei zhang Yu-Hao Luo Hui Wang Liang Zhao Department of Pathology Nanfang Hospital Southern Medical University Department of Medical Oncology Affiliated Tumor Hospital of Guangzhou Medical University Department of Pathology School of Basic Medical Sciences Southern Medical University

Long non-coding RNAs(lnc RNAs), a newly discovered class of nc RNA molecules, have been widely accepted as crucial regulators of various diseases including cancer. Increasing numbers of studies have demonstrated that lnc RNAs are involved in diverse physiological and pathophysiological processes, such as cell cycle progression, chromatin remodeling, gene transcription, and posttranscriptional processing. Aberrant expression of lnc RNAs frequently occurs in gastrointestinal cancer and plays emerging roles in cancer metastasis. In this review, we focus on and outline the regulatory functions of recently identified metastasis-associated lnc RNAs, and evaluate the p o t e n t i a l r o l e s o f l n c R N A s a s n o v e l d i a g n o s t i c biomarkers and therapeutic targets in gastrointestinal cancer.

关键词： gastrointestinal cancer Tumor metastasis Long noncoding RNAs epithelial-to-mesenchymal transition MicroR NAs

Over-sampling basis expansion model aided channel estimation for OFDM systems with ICI

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The Journal of China Universities of Posts and Telecommunications 2008年第4期15卷 7-13页

作者： LIU Si-yang LIU Yuan-an WANG fei-fei XIE Gang zhang Ran-ran Key Laboratory of Universal Wireless Communications (Beijing University of Posts and Telecommunications) Ministry of Education Beijing 100876 China

The rapid variation of channel can induce the intercarrier interference in orthogonal frequency-division multiplexing （OFDM） systems. Intercarrier interference will significantly increase the difficulty of OFDM channel estimation because too many channel coefficients need be estimated. In this article, a novel channel estimator is proposed to resolve the above problem. This estimator consists of two parts： the channel parameter estimation unit （CPEU）, which is used to estimate the number of channel taps and the multipath time delays, and the channel coefficient estimation unit （CCEU）, which is used to estimate the channel coefficients by using the estimated channel parameters provided by CPEU. In CCEU, the over-sampling basis expansion model is resorted to solve the problem that a large number of channel coefficients need to be estimated. Finally, simulation results are given to scale the performance of the proposed scheme.

关键词： OFDM ICI over-sampling basis expansion model (OBEM)

Constructing robust NiFe LDHs-NiFe alloy gradient hybrid bifunctional catalyst for overall water splitting:one-step electrodeposition and surface reconstruction

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Rare Metals 2023年第7期42卷 2272-2283页

作者： Yi-fei Chen Jia-Hong Li Tian-Tian Liu Si-Hang You Peng Liu Fu-Jin Li Meng-Qi Gao Shu-Guang Chen fei-fei zhang School of Materials Science and Engineering Changsha University of Science and TechnologyChangsha410114China Faculty of Engineering Department of Materials Science and EngineeringNational University of SingaporeSingapore117576Singapore School of Materials Science and Engineering Jilin UniversityChangchun130022China

NiFe layered double hydroxides(NiFe LDHs)have been intensively developed for the oxygen evolution reaction(OER)in alkaline media;however,their unsatisfactory hydrogen evolution reaction(HER)performance limits their practical application in overall water ***,a simple and efficient one-step electrodeposition method is used to accomplish in situ growth of NiFe LDHsNiFe alloy gradient hybrid coatings on a carbon cloth(CC).Within the binder-free electrode,NiFe LDHs nanosheets with a low-crystalline nature exhibit highly active bifunctional OER/HER activities,and the NiFe alloy acts as a stable electron highway and strong skeleton bridge between NiFe LDHs and the *** the electrodes are simultaneously employed as the cathode and anode for overall water splitting,they require low cell potentials of 1.441 V at10 mA·cm^(-2)and 1.703 V at 100 mA·cm^(-2),respectively,and they demonstrate outstanding stability at a current density greater than 100 mA·cm^(-2)for more than 100 *** is one of the best bifunctional OER and HER catalysts for overall water *** lattice defects and surface reconstructions crucially contribute to the bifunctional OER/HER activities of NiFe *** simple and scalable synthesis approach presents an intriguing paradigm for industrial production,and the fabricated electrode has potential application in high-current-density water splitting.

关键词： Bifunctional Electrodeposition Gradient hybrid NiFe layered double hydroxides(NiFe LDHs) Overall water splitting

Highly anti-corrosive NiFe LDHs–NiFe alloy hybrid enables long-term stable alkaline seawater electrolysis

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Rare Metals 2024年第9期43卷 4321-4332页

作者： Jia-Hong Li Hao Chen Si-Hang You Gan-Xin Yang Peng Liu Meng-Qi Gao Shu-Guang Chen fei-fei zhang School of Materials Science and Engineering Changsha University of Science and TechnologyHunan 410114China Department of Materials Science and Engineering Faculty of EngineeringNational University of SingaporeSingapore 117576Singapore School of Materials Science and Engineering Jilin UniversityJilin 130022China

Owing to the significant potential of alkalin seawater electrolysis for converting surplus power into eco friendly hydrogen fuel,we developed bifunctional elec trodes that integrate low-crystalline NiFe LDHs and amorphous NiFe alloy on a Ni foam(NF)substrate to enhance this *** by the battery-like charac teristics of NiFe LDHs,an anti-corrosive and active oute layer of NiFe^(vac)OOH continuously forms over time in th hybrid on the anode for the oxygen evolution reaction(OER),effectively mitigating powder shedding caused by corrosion induced by multiple anions in *** while,the strong bond between the hybrid and the NF substrate maintains intact hybrid coatings to ensure a rel atively high overall conductivity of the electrodes,signif icantly reducing the negative effects of structura degradation during the OER and hydrogen evolution reaction(HER),as well as the accumulation of contami nants on the electrode *** long-term tests,thes bifunctionalhybridelectrodesmaintained stable performance,even at a high current density o500 mA·cm^(-2).The cell voltage increased by only 88 m V over 1000 h to 1.970 V during saline electrolysis and by103 mV over 500 h to 2.062 V during seawater electroly ***,this study provides valuable insights into efficient and stable seawater electrolysis using NiFe LDHs–NiFe alloy hybrids.

关键词： NiFe LDHs Bifunctional Corrosion Stability Seawater electrolysis

Nanocavity enriched CuPd alloy with high selectivity for CO_(2) electroreduction toward C_(2)H_(4)

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Rare Metals 2024年第4期43卷 1513-1523页

作者： Ze-Yu zhang Hai-Bin Wang fei-fei zhang Jing-Wei Li Xin-Zhuo Hu Si-Wei Yan Yi-Ming Bai Xun zhang Gu-Rong Shen Peng-fei Yin Jing Yang Cun-Ku Dong Jing Mao Hui Liu Xi-Wen Du Institute of New-Energy Materials School of Materials Science and EngineeringTianjin UniversityTianjin300350China

Electrocatalysis of CO_(2)reduction reaction is an effective way to convert CO_(2)into high value-added products,but the selectivity of Cu-based catalysts for C2+products needs to be improved due to the high energy barrier of C-C ***,a viable catalyst design strategy to decrease energy barrier of C-C coupling should be put ***,a nanocavity-enriched CuPd single atom alloy(CuPd SAA)catalyst is designed to promote CC coupling *** faradaic efficiency of CuPd SAA for ethylene and C_(2+)reaches 75.6%and 85.7%at-0.7 V versus reversible hydrogen electrode(RHE),*** on the results given by in situ characterization,the porous hollow structure dramatically increases the ratio of the linear-bond*CO,thus enhancing the faradaic efficiency for *** functional theory(DFT)calculation reveals that the Pd doping can regulate the electronic structure of neighboring Cu atoms to decrease the energy barrier of C-C coupling,further improving the faradaic *** work provides a new idea for designing catalyst with high selectivity for ethylene.

关键词： Adsorption configuration C-C coupling CO_(2) electrocatalysis Ethylene Single atom alloy

Heat exposure and hospitalizations for chronic kidney disease in China: a nationwide time series study in 261 major Chinese cities

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Military Medical Research 2024年第4期11卷 469-478页

作者： Fu-Lin Wang Wan-Zhou Wang fei-fei zhang Su-Yuan Peng Huai-Yu Wang Rui Chen Jin-Wei Wang Peng-fei Li Yang Wang Ming-Hui Zhao Chao Yang Lu-Xia zhang Institute of Medical Technology Peking University Health Science CenterBeijing 100191China National Institute of Health Data Science at Peking University Beijing 100191China Department of Occupational and Environmental Health Sciences School of Public HealthPeking UniversityBeijing 100191China Renal Division Department of MedicinePeking University First HospitalPeking University Institute of NephrologyBeijing 100034China Research Units of Diagnosis and Treatment of Immune-Mediated Kidney Diseases Chinese Academy of Medical SciencesBeijing 100034China Advanced Institute of Information Technology Peking UniversityHangzhou 311215China National Climate Center China Meteorological AdministrationBeijing 100081China Peking-Tsinghua Center for Life Sciences Beijing 100034China

Background:Climate change profoundly shapes the population health at the global ***,there was still insufficient and inconsistent evidence for the association between heat exposure and chronic kidney disease(CKD).Methods:In the present study,we studied the association of heat exposure with hospitalizations for cause-specific CKD using a national inpatient database in China during the study period of hot season from 2015 to *** time-series regression models and random-effects Meta-analysis were developed to estimate the city-specific and national averaged associations at a 7 lag-day span,***:A total of 768,129 hospitalizations for CKD was recorded during the study *** results showed that higher temperature was associated with elevated risk of hospitalizations for CKD,especially in sub-tropical *** a 1℃ increase in daily mean temperature,the cumulative relative risks(RR)over lag 0-7 d were 1.008[95% confidence interval(CI)1.003-1.012]for *** attributable fraction of CKD hospitalizations due to high temperatures was 5.50%.Stronger associations were observed among younger patients and those with obstructive *** study also found that exposure to heatwaves was associated with added risk of hospitalizations for CKD compared to non-heatwave days(RR=1.116,95%CI 1.069-1.166)above the effect of daily mean ***:Short-term heat exposure may increase the risk of hospitalization for *** findings provide insights into the health effects of climate change and suggest the necessity of guided protection strategies against the adverse effects of high temperatures.

关键词： Chronic kidney disease Hospitalization Climate change Temperature Time-series study

Efficacy of Medication Directed by Home-Monitoring Cardiac Resynchronization Therapy in Chronic Heart Failure Patients

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Chinese Medical Sciences Journal 2014年第1期29卷 61-62页

作者： Hao Yang fei-fei zhang Xin-hui Peng Dong-hua Zhao Jian Peng Department of Cardiology Nanfang HospitalSouthern Medical University

PATIENTS with chronic heart failure(CHF)have a high incidence of atrial/ventricular arrhythmias which seriously affect life span and quality of *** resynchronization therapy(CRT)can improve cardiac function and reverse myocardial remodeling,therefore improving the quality of life and reducing *** with Home-Monitoring(HM)can be used to monitor cardiac arrhythmias and other

关键词：监测中心药物治疗心力衰竭心脏患者慢性家庭再同步

Follicle stimulating hormone controls granulosa cell glutamine synthesis to regulate ovulation

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Protein & Cell 2024年第7期15卷 512-529页

作者： Kai-Hui zhang fei-fei zhang Zhi-Ling zhang Ke-fei Fang Wen-Xing Sun Na Kong Min Wu Hai-Ou Liu Yan Liu Zhi Li Qing-Qing Cai Yang Wang Quan-Wei Wei Peng-Cheng Lin Yan Lin Wei Xu Cong-Jian Xu Yi-Yuan Yuan Shi-Min Zhao The Obstetrics&Gynecology Hospital of Fudan University State Key Laboratory of Genetic EngineeringFudan UniversityShanghai 200090China Shanghai Key Laboratory of Metabolic Remodeling and Children’s Hospital of Fudan UniversityShanghai 200032China School of Life Sciences and Institutes of Biomedical Sciences Fudan UniversityShanghai 200438China Department of Nutrition and Food Hygiene School of Public HealthNantong UniversityNantong 226019China Reproductive Medicine Center The Affiliated Drum Tower Hospital of Nanjing University Medical SchoolNanjing 210008China Shanghai Fifth People’s Hospital of Fudan University Fudan UniversityShanghai 200240China Department of Animal Science and Technology Nanjing Agricultural UniversityNanjing 210014China Key Laboratory for Tibet Plateau Phytochemistry of Qinghai Province College of PharmacyQinghai University for NationalitiesXining 810007China Pediatric Research Institute Children’s Hospital Affiliated to Shandong University(Jinan Children’s Hospital)Jinan 250022China

Polycystic ovary syndrome(PCOS)is the leading cause of anovulatory *** understanding of the ovulation drivers hinders PCOS ***,we report that follicle stimulating hormone(FSH)controls follicular fluid(FF)glutamine levels to determine *** ovulation starts from FF-exposing granulosa cell(GC)*** glutamine,which decreases in pre-ovulation porcine FF,elevates in PCOS patients ***-glutamine chow to elevate FF glutamine inhibits mouse GC apoptosis and induces hormonal,metabolic,and morphologic PCOS ***,follicle-development-driving FSH promotes GC glutamine synthesis to elevate FF glutamine,which maintain follicle wall integrity by inhibiting GC apoptosis through inactivating ASK1-JNK apoptotic *** and glutamine inhibit the rapture of cultured murine *** removal or ASK1-JNK pathway activation with metformin or AT-101 reversed PCOS traits in PCOS models that are induced with either glutamine or *** suggest that glutamine,FSH,and ASK1-JNK pathway are targetable to alleviate PCOS.

关键词： ovulation glutamine granulosa cells PCOS FSH

Affective rating ranking based on face images in arousal-valence dimensional space

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Frontiers of Information Technology & Electronic Engineering 2018年第6期19卷 783-795页

作者： Guo-peng XU Hai-tang LU fei-fei zhang Qi-rong MAO School of Computer Science and Communication Engineering Jiangsu University

In dimensional affect recognition, the machine learning methods, which are used to model and predict affect, are mostly classification and regression. However, the annotation in the dimensional affect space usually takes the form of a continuous real value which has an ordinal property. The aforementioned methods do not focus on taking advantage of this important information. Therefore, we propose an affective rating ranking framework for affect recognition based on face images in the valence and arousal dimensional space. Our approach can appropriately use the ordinal information among affective ratings which are generated by discretizing continuous ***, we first train a series of basic cost-sensitive binary classifiers, each of which uses all samples relabeled according to the comparison results between corresponding ratings and a given rank of a binary classifier. We obtain the final affective ratings by aggregating the outputs of binary classifiers. By comparing the experimental results with the baseline and deep learning based classification and regression methods on the benchmarking database of the AVEC 2015 Challenge and the selected subset of SEMAINE database, we find that our ordinal ranking method is effective in both arousal and valence dimensions.

关键词： Ordinal ranking Dimensional affect recognition Valence Arousal Facial image processing