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A memristive-photoconductive transduction methodology for accurately nondestructive memory readout

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Light(Science & Applications) 2024年第9期13卷 1801-1808页

作者： Zhe Zhou Yueyue Wu Keyuan Pan Duoyi Zhu Zifan Li Shiqi Yan Qian Xin Qiye Wang Xinkai Qian fei xiu Wei Huang Juqing Liu Key Laboratory of Flexible Electronics(KLOFE)&Institute of Advanced Materials(IAM) Nanjing Tech University(NanjingTech)30 South Puzhu RoadNanjing 211816China Shandong Technology Center of Nanodevices and Integration School of MicroelectronicsShandong UniversityJinan 250100China Shaanxi Institute of Flexible Electronics(SIFE) Northwestern Polytechnical University(NPU)127 West Youyi RoadXi’an 710072China

Crossbar resistive memory architectures enable high-capacity storage and neuromorphic computing,accurate retrieval of the stored information is a prerequisite during read ***,conventional electrical readout normally suffer from complicated process,inaccurate and destructive reading due to crosstalk effect from sneak path *** we report a memristive-photoconductive transduction(MPT)methodology for precise and nondestructive readout in a memristive crossbar *** individual devices present dynamic filament form/fuse for resistance modulation under electric stimulation,which leads to photogenerated carrier transport for tunable photoconductive response under subsequently light pulse *** coherent signal transduction can be used to directly detect the memorized on/off states stored in each cell,and a prototype 4*4 crossbar memories has been constructed and validated for the fidelity of crosstalk-free readout in recall process.

关键词： crosstalk precise enable

Investigation of the dynamic characteristics of a dual rotor system and its start-up simulation based on finite element method

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浙江大学学报（英文版）A辑：应用物理与工程 2013年第4期14卷 268-280页

作者： Zhong-xiu fei Shui-guang TONG Chao WEI Institute of Chemical Machinery Engineering Zhejiang University Mechanical Design Institute Zhejiang University Institute of Thermal Engineering and Power Systems Zhejiang University

Recently,the finite element method(FEM) has been commonly applied in the engineering analysis of rotor *** moments,rotary inertia,transverse shear deformation and gravity can be included in computational models of rotor-bearing *** this paper,a finite element model and its solution method are presented for the calculation of the dynamics of dual rotor systems.A typical structure with two rotor shafts is discussed and the procedure for obtaining the coupling motion equations of the subsystems is illustrated.A computer program is developed to solve critical speeds and to simulate the transient *** influence of gyroscopic moments on co-rotation and counter-rotation is analyzed,and the effect of the speed ratio on critical speed is *** dynamic characteristics under different conditions of increasing speed during start-up are demonstrated by comparison with transient nodal *** presented model provides a complete foundation for further investigation of the dynamics of dual rotor systems.

关键词： Dual rotor system Critical speed Transient response Finite element method(FEM)

聚苯乙烯微塑料对污水中胞外耐药基因的影响及其机制

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环境科学 2024年第6期45卷 3671-3678页

作者：周帅黄啊潮黄泽枫李伦福杨锋娟陈安琪修斐晨高媛媛南华大学污染控制与资源化技术湖南省高校重点实验室衡阳421001 南华大学土木工程学院衡阳421001 南华大学稀有金属矿产开发与废物地质处置技术湖南省重点实验室衡阳421001 南华大学衡阳医学院病原生物学研究所衡阳421001

微塑料(MPs)和抗生素耐药基因(ARGs)是共存于污水处理厂中的典型新污染物.MPs已被证明能够改变污泥中ARGs的分布模式,但其对污水中胞外ARGs(fe ARGs)的影响及机制仍不清楚.采用荧光定量PCR技术探究了典型MPs(聚苯乙烯PS)暴露60 d后污水... 详细信息

微塑料(MPs)和抗生素耐药基因(ARGs)是共存于污水处理厂中的典型新污染物.MPs已被证明能够改变污泥中ARGs的分布模式,但其对污水中胞外ARGs(fe ARGs)的影响及机制仍不清楚.采用荧光定量PCR技术探究了典型MPs(聚苯乙烯PS)暴露60 d后污水中fe ARGs(包括tet C、tet O、sul1和sul2)的动态变化特征及机制.结果表明,四环素类fe ARGs绝对丰度在nm级和mm级PS暴露下分别降低了28.4%~76.0%和35.2%~96.2%,在μm级PS暴露下变化了-55.4%~122.4%.PS对磺胺类sul1的促进效果呈nm级>μm级>mm级趋势,且ρ(PS)为50 mg·L^(-1)对sul1丰度扰动幅度更大.磺胺类sul2的相对丰度在μm级和mm级PS暴露后分别削减了25.4%~42.6%和46.1%~90.3%,在nm级PS暴露后增加了1.9~3.9倍;ρ(PS)为50 mg·L^(-1)对sul2的削减作用高于ρ(PS)为0.5 mg·L^(-1).Pearson相关性分析显示,PS暴露下fe ARGs相对丰度与细胞膜通透性和典型可移动遗传元件(int I1)丰度成正相关,与活性氧水平成负相关.研究结果阐明了PS对污水中fe ARGs的影响及其机制,可为污水中MPs与ARGs复合污染的防治提供科学依据.

关键词：微塑料(MPs) 聚苯乙烯(PS) 胞外耐药基因(feARGs) 污水影响机制

A latent form of essential thrombocythemia presenting as portal cavernoma

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World Journal of Gastroenterology 2009年第42期15卷 5368-5370页

作者： Xiao-Yan Cai Wei Zhou De-fei Hong xiu-Jun Cai Department of General Surgery Sir Run Run Shaw Hospital College of Medicine Sir Run Run Shaw Institute of Clinical Medicine of Zhejiang University Hangzhou 310016 Zhejiang Province China

Essential thrombocythemia with abdominal thrombotic is frequently associated complications including portal cavernoma as a consequence of chronic portal vein thrombosis. Essential thrombocythemia in a latent form is difficult to identify at onset due to the absence of an overt disease phenotype. In the presented case report, the diagnosis of essential thrombocythemia was initially missed because the typical disease phenotype was masked by bleeding and hypersplenism. The correct diagnosis was only reached when the patient experienced persistent thrombocytosis and pseudohyperkalemia after a shunt operation.

关键词： Essential thrombocythemia Portal cavernoma Portal vein thrombosis Pseudohyperkalemia

Discovery of a Homolog of Siderophilin in a Plant

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Journal of Integrative Plant Biology 2005年第12期47卷 1409-1411页

作者： Yun-Biao fei Peng-xiu CAO Su-Qin GAO Ling-Bo WEI Bin WANG Institute of Genetics and Developmental Biology the Chinese Academy of Sciences Beijing 100101 China

Members belonging to the siderophilin family are iron-binding and iron-transporting proteins, which includes transferrin and lactoferrin. They have only been found in animals previously. If siderophilin could be found in and isolated from a plant, its production and subsequent extensive application could be increased. The present study is the first to report the discovery of a homolog of siderophilin in a plant. In order to purify antifreeze proteins from Ammopiptanthus mongolicus （Maxim.） Cheng f., the authors processed the proteins from the leaves using techniques such as column chromatography using DEAE-Cellulose-52, gel filtration via Sephacryl S-100 HR medium, hydrophobic interaction chromatography, and sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Mass spectroscopy was performed on the three proteins purified and the sequence of one of the proteins （containing 32 amino acids） was found to have 97% homology with the corresponding part of one type of human lactoferrin. Moreover, one of the two peptides belongs to an iron-binding domain. So, it is possible that siderophilin also exists in plants and plays a role as an antibacterial and antifungal, among other actions.

关键词： antibacterial iron-binding domain lactoferrin siderophilin transferrin.

New strategies for asymmetric photocatalysis: asymmetric organocatalytic/photoredox relay catalysis for efficient synthesis of polycyclic compounds containing vicinal amino alcohols

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Science China Chemistry 2024年第3期67卷 945-952页

作者： Jia-Lu Zhang Wen-Bo He xiu-Qin Hu Peng-fei Xu State Key Laboratory of Applied Organic Chemistry College of Chemistry and Chemical EngineeringLanzhou UniversityLanzhou 730000China State Key Laboratory of Veterinary Etiological Biology College of Veterinary MedicineLanzhou UniversityLanzhou Veterinary Research InstituteChinese Academy of Agricultural SciencesLanzhou 730000China MOE Frontiers Science Center for Rare Isotopes Lanzhou UniversityLanzhou 730000China

An asymmetric catalytic strategy in photocatalysis utilizing a chirality-induced approach through an organocatalytic/photoredox relay catalysis strategy is successfully achieved for the rapid construction of polycyclic compounds containing vicinal amino alcohols in a one-pot protocol. This methodology facilitates the efficient synthesis of diverse substituted polycyclic tetrahydroquinoline and benzofuran-derived vicinal amino alcohols, each containing five consecutive chiral centers, with high yields,excellent diastereoselectivities and enantioselectivities(up to 95% yield, >20:1 dr and 98% ee), under mild reaction conditions driven by sequential bifunctional squaramide organocatalyst-catalyzed [4+2] annulation and photocatalyst-catalyzed ketyl radical addition cyclization reaction process. Furthermore, investigations into the stereoselectivity mechanism and high-resolution mass spectrometry(HRMS) experiments on free radical trapping have provided evidence for elucidating the detailed mechanism of chirality-induced processes and chiral intermediate conversions in this procedure.

关键词： enantioselective photocatalysis asymmetric organocatalytic/photocatalysis relay catalysis five consecutive chiral centers chirality-induced strategy chirality vicinal amino alcohols

Bleb-associated endophthalmitis treated by sclera patch graft, vitrectomy and endoscopic cyclophotocoagulation

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Chinese Medical Journal 2012年第18期125卷 3344-3345页

作者： ZHENG Peng-fei PANG xiu-qin Beijing Tongren Eye Center Beijing Tongren Hospital CapitalMedical University China Beijing 100730

Background Bleb-associated endophthalmitis （BAE） is a rare but severe complication of trabeculectomy with poor outcome. Various surgical methods were explored to treat such patients. However, there is no defined protocol. The aim of this study was to describe a new combined operation, and to demonstrate the outcome of the treatment. Methods Nine patients with BAE were enrolled in our study. The combined operation including pars plana vitrectomy （PPV）, sclera patch graft （SPG） and endoscopic cyclophotocoagulation （ECP） was used to treat these patients. Results In the follow-up of 18-24 months, all patients with the endophthalmitis were cured, the useful visual acuity was preserved in 7 patients, and the intraocular pressure （lOP） of 8 patients was controlled just after first operation, only one needed another trans-scleral cyclophotocoagulation. Conclusion This combined operation is a useful method for treating the patients with BAE, with SPG and vitrectomy to control the endophthalmitis and ECP to balance the postoperative lOP.

关键词： bleb-associated endophthalmitis sclera patch graft," vitrectomy endoscopic cyclophotocoagulation

玉米秸秆穰叶对肉羊生长性能、养分表观消化率、血清生化指标及免疫指标的影响

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饲料研究 2024年第1期47卷 1-4页

作者：刘海燕李雪龙王彦靖王秀飞张頔赵胜楠杨瑞红吉林省农业科学院吉林吉林130119 洮南市农业技术推广中心吉林洮南137100

试验旨在研究玉米秸秆穰叶对肉羊生长性能、养分表观消化率及血清生化指标的影响。选取健康状况较好、体重(30.0±3.0)kg的母羊30只,按体重相近原则,随机分为2组,每组3个重复,每个重复5只羊。对照组以整株玉米秸秆作为粗饲料,试验组以... 详细信息

试验旨在研究玉米秸秆穰叶对肉羊生长性能、养分表观消化率及血清生化指标的影响。选取健康状况较好、体重(30.0±3.0)kg的母羊30只,按体重相近原则,随机分为2组,每组3个重复,每个重复5只羊。对照组以整株玉米秸秆作为粗饲料,试验组以玉米秸秆穰叶作为粗饲料,试验组和对照组精料一致。预试期10 d,正式试验期90 d。结果显示,与对照组相比,试验组肉羊的平均日增重提高了10.58%,平均日干物质采食量提高了1.01%,料重比降低了8.66%。试验组肉羊对饲粮中干物质、粗蛋白、粗脂肪、中性洗涤纤维、酸性洗涤纤维、钙及磷的表观消化率分别比对照组提高了6.52%、8.69%、9.43%、8.17%、8.43%、5.87%和6.51%。试验组肉羊血清中总蛋白含量、球蛋白含量及碱性磷酸酶活性分别比对照组提高了3.41%、10.70%和12.42%,尿素氮含量降低了5.00%。试验组肉羊血清中免疫球蛋白A、免疫球蛋白M、免疫球蛋白G、补体C3和补体C分别比对照组提高了5.89%、7.90%、7.58%、6.95%和2.66%。研究表明,与整株玉米秸秆相比,玉米秸秆穰叶是草食家畜的一种优质粗饲料。

关键词：玉米秸秆穰叶肉羊生长性能血清生化指标

Association of miRNA-492 rs2289030 G>C and miRNA-938rs2505901 T>C Gene Polymorphisms with Biliary Atresia Susceptibility

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Biomedical and Environmental Sciences 2021年第7期34卷 577-580页

作者： SU Liang TIAN Yan FU Ming ZHANG Rui Zhong OU xiu fei XIA Hui Min LI Rui Zhuo Provincial Key Laboratory of Research in Structure Birth Defect Disease and Department of Pediatric Surgery Guangzhou Women and Children's Medical CenterGuangzhou Medical UniversityGuangzhou 510623GuangdongChina

Biliary atresia(BA)is one of the most common and enigmatic forms of neonatal cholestasis and is characterized by inflammation and obstruction of extrahepatic bile ducts resulting in biliary cirrhosis,which occurs in 1 in 8,000 to 1 in 18,000 live *** of the mechanisms underlying BA is crucial for early diagnosis,intervention,and better *** etiology of BA remains unclear,and currently,noncoding and epigenetic factors,rather than classic genetic alterations,are assumed to be responsible for genetic predisposition to BA.

关键词： res alterations diagnosis